AIとIPFと癒しの音楽

特発性肺線維症 idiopathic pulmonary fibrosis (IPF)患者によるIPF関連学術情報の収集とシェア。癒しの音楽もお届けしています。

2023-03-01から1ヶ月間の記事一覧

マクロファージでの TIM-3 の過剰発現は、マウスの肺線維症の病因を悪化させる

" Overexpression of TIM-3 in macrophages aggravates pathogenesis of pulmonary fibrosis in mice Y Wang, Q Kuai, F Gao, Y Wang, M He… - American journal of …, 2019 - atsjournals.org … TIM-3 expression was increased both in patients with IPF …

組織線維症における抗炎症性サイトカイン インターロイキン 10 の役割

" The role of the anti-inflammatory cytokine interleukin-10 in tissue fibrosis EH Steen, X Wang, S Balaji, MJ Butte… - Advances in wound …, 2020 - liebertpub.com … IL-10 signaling mechanisms. We then discuss literature on fibrosis and IL-1…

IL-10のヒドロゲルベースの送達は、マウスのブレオマイシン誘発肺線維症の治療を改善

" Hydrogel-based delivery of Il-10 improves treatment of bleomycin-induced lung fibrosis in mice EA Shamskhou, MJ Kratochvil, ME Orcholski, N Nagy… - Biomaterials, 2019 - Elsevier … delivery system for IL-10 attenuates lung fibrosis in an …

TNF-αおよびIL-10は、ヒトマクロファージにおけるCXCL13発現を制御

" TNF-α and IL-10 control CXCL13 expression in human macrophages N Bellamri, R Viel, C Morzadec, V Lecureur… - The Journal of …, 2020 - journals.aai.org … especially increased in IPF patients who had inflammation … with IPF have substantia…

IL-10/IL-10受容体1経路は、間質性肺炎組織に由来する肺線維芽細胞の生存率とコラーゲン合成を促進

" IL‑10/IL‑10 receptor 1 pathway promotes the viability and collagen synthesis of pulmonary fibroblasts originated from interstitial pneumonia tissues H Ye, J Pan, X Cai, Z Yin, L Li… - Experimental and …, 2022 - spandidos-publications.com…

IPF Weekly Update

<><><> 23/03/23 [HTML] No increased prevalence of autoantibodies neutralizing type I IFNs in idiopathic pulmonary fibrosis patients Q Philippot, P Bastard, A Puel, JL Casanova, A Cobat… - Respiratory Research, 2023 … some auto-Abs in IPF p…

胚性肺発生および特発性肺線維症におけるインスリン様成長因子シグナル伝達コンポーネントの転写プロファイリング

" Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis V Kheirollahi, A Khadim, G Kiliaris, M Korfei… - Cells, 2022 - mdpi.com … Our gene expression pr…

慢性過敏性肺炎の呼吸器マイクロバイオームは、特発性肺線維症のそれとは異なる

" The respiratory microbiome in chronic hypersensitivity pneumonitis is distinct from that of idiopathic pulmonary fibrosis R Invernizzi, BG Wu, J Barnett, P Ghai… - American Journal of …, 2021 - atsjournals.org … IPF and did not associate…

肺線維症における肺マイクロバイオームの進化する役割

" The evolving role of the lung microbiome in pulmonary fibrosis JH Lipinski, BB Moore… - American Journal of …, 2020 - journals.physiology.org … lung microbiome in IPF, … microbiome-based therapies in pulmonary fibrosis. This reviewwill f…

特発性肺線維症におけるマイクロバイオームとバイロームの役割

" The role of microbiome and virome in idiopathic pulmonary fibrosis P Ntolios, V Tzilas, E Bouros, E Avdoula… - Biomedicines, 2021 - mdpi.com … incidence of both sporadic and familial IPF [16,17]. In this review, we summarize the availabl…

特発性肺線維症の急性増悪における感染と呼吸器マイクロバイオームの寄与

" [HTML] The contribution of infection and the respiratory microbiome in acute exacerbations of idiopathic pulmonary fibrosis R Invernizzi, PL Molyneaux - European Respiratory Review, 2019 - Eur Respiratory Soc … microbiome plays a role in…

特発性肺線維症における生活の質、不安、抑うつに対する緩和ケアの影響:無作為化比較パイロット研究

" [HTML] The impact of palliative care on quality of life, anxiety, and depression in idiopathic pulmonary fibrosis: a randomized controlled pilot study K Janssen, D Rosielle, Q Wang… - Respiratory …, 2020 - respiratory-research.biomedcent…

IPF Weekly Update

<><><> 23/03/18 [PDF] 111 A systematic review exploring factors associated with palliative care utilisation in patients with Idiopathic Pulmonary Fibrosis H Amin, T Gatheral, A Gadoud, A Khan - BMJ Supportive & Palliative Care, 2023 … with…

ピルフェニドンは、Wnt/GSK-3β/β-カテニンおよび TGF-β1/Smad2/3 シグナル伝達経路を調節することにより、in vitro および in vivo で肺線維症を軽減

" [HTML] Pirfenidone alleviates pulmonary fibrosis in vitro and in vivo through regulating Wnt/GSK-3β/β-catenin and TGF-β1/Smad2/3 signaling pathways Q Lv, J Wang, C Xu, X Huang, Z Ruan, Y Dai - Molecular Medicine, 2020 - Springer … In sum…

TGF-β-WNTクロストークの阻害による肺線維症に対するヒト気管支上皮細胞由来の細胞外小胞療法

" Human bronchial epithelial cell‐derived extracellular vesicle therapy for pulmonary fibrosis via inhibition of TGF‐β‐WNT crosstalk T Kadota, Y Fujita, J Araya, N Watanabe… - Journal of …, 2021 - Wiley Online Library … )-β and WNT, has be…

ベツリン酸は、Wnt / β-カテニンシグナル伝達に効果的に介入することにより、ブレオマイシン誘発肺線維症を軽減

" Betulinic acid attenuated bleomycin-induced pulmonary fibrosis by effectively intervening Wnt/β-catenin signaling X Li, X Liu, R Deng, S Gao, Q Jiang, R Liu, H Li, Y Miao… - Phytomedicine, 2021 - Elsevier … pulmonary fibrosis remain uncl…

非標準的な Wnt シグナル伝達は、肺線維症における筋線維芽細胞の分化を促進

" Noncanonical Wnt Signaling Promotes Myofibroblast Differentiation in Pulmonary Fibrosis T Liu, F Gonzalez De Los Santos, M Hirsch… - American Journal of …, 2021 - atsjournals.org … and human idiopathic pulmonary fibrosis, wherein Wnt/β-……

ポリスチレンマイクロプラスチックの気管内投与は、マウスの酸化ストレスと Wnt/β-カテニンシグナル伝達経路を活性化することにより肺線維症を誘発

" [HTML] Intratracheal administration of polystyrene microplastics induces pulmonary fibrosis by activating oxidative stress and Wnt/β-catenin signaling pathway in mice X Li, T Zhang, W Lv, H Wang, H Chen, Q Xu… - Ecotoxicology and …, 2022…

タバコの煙で不活性化されたSIRT1は、肺胞上皮2型細胞のオートファジー依存性老化を促進して肺線維症を誘発

" Cigarette smoke-inactivated SIRT1 promotes autophagy-dependent senescence of alveolar epithelial type 2 cells to induce pulmonary fibrosis Y Zhang, W Huang, Z Zheng, W Wang, Y Yuan… - Free Radical Biology …, 2021 - Elsevier … /autophagy …

IPF Weekly Update

<><><> [HTML] Wilms Tumor 1-Driven Fibroblast Activation and Subpleural Thickening in Idiopathic Pulmonary Fibrosis PR Gajjala, P Singh, V Odayar, HH Ediga… - International Journal of …, 2023 … Idiopathic pulmonary fibrosis (IPF) is a prog…

オートファジー阻害を介した上皮間葉転換は、肺線維症における局所筋線維芽細胞分化を増強

" [HTML] Autophagy inhibition-mediated epithelial–mesenchymal transition augments local myofibroblast differentiation in pulmonary fibrosis C Hill, J Li, D Liu, F Conforti, CJ Brereton, L Yao… - Cell death & …, 2019 - nature.com … IPF. How…

特発性肺線維症におけるオートファジー、アポトーシス、変性タンパク質応答、および肺機能

" Autophagy, apoptosis, the unfolded protein response, and lung function in idiopathic pulmonary fibrosis P Sharma, J Alizadeh, M Juarez, A Samali, AJ Halayko… - Cells, 2021 - mdpi.com … We also hypothesized that co-localized markers of UP…

肺感染症および炎症性疾患におけるオートファジーの保護機能

" Protective features of autophagy in pulmonary infection and inflammatory diseases K Wang, Y Chen, P Zhang, P Lin, N Xie, M Wu - Cells, 2019 - mdpi.com … in human IPF pathogenesis. Interestingly, human IPF fibroblasts show reduced autopha…

オートファジーと肺線維症

" Autophagy and pulmonary fibrosis X Lv, K Li, Z Hu - Autophagy: Biology and Diseases: Clinical Science, 2020 - Springer … with IPF shows obstructed autophagic flux and decreased autophagy function which ischaracterized by the decrease in …

肺線維症疾患の重要な治療標的であるオートファジー

" Autophagy, an important therapeutic target for pulmonary fibrosis diseases H Zhao, Y Wang, T Qiu, W Liu, P Yao - Clinica Chimica Acta, 2020 - Elsevier … pulmonary fibrosis. In this review, the role and signalling mechanisms of autophagy …

肺線維症におけるストレス活性化プロテインキナーゼの病態生理学的役割

" Pathophysiological roles of stress-activated protein kinases in pulmonary fibrosis Y Kasuya, JD Kim, M Hatano, K Tatsumi… - International Journal of …, 2021 - mdpi.com … the stepwise elevation of intrinsic p38 signaling in the lungs … pa…

肺疾患における調整された壊死。 necroptosisとferroptosisに焦点:

" Regulated necrosis in pulmonary disease. A focus on necroptosis and ferroptosis S Minagawa, M Yoshida, J Araya, H Hara… - American Journal of …, 2020 - atsjournals.org … Epithelial–mesenchymal interactions are believed to be important in…

特発性肺線維症患者の末梢血単核細胞におけるサーチュイン 1 (SIRT1)レベルの評価

" [HTML] Evaluation of Sirtuin 1 Levels in Peripheral Blood Mononuclear Cells of Patients With Idiopathic Pulmonary Fibrosis K Deskata, F Malli, R Jagirdar, GD Vavougios… - Cureus, 2022 - cureus.com … in plasma and PBMCs of IPF subjects. S…

サーチュイン 6 は、ヒト胎児肺線維芽細胞のトランスフォーミング増殖因子 -β1/Smad2 および核因子 -κB シグナル伝達経路を不活性化することにより、筋線維芽細胞の分化を阻害

" Sirtuin 6 inhibits myofibroblast differentiation via inactivating transforming growth factor‐β1/Smad2 and nuclear factor‐κB signaling pathways in human fetal lung … Q Zhang, W Tu, K Tian, L Han, Q Wang… - Journal of cellular …, 2019 - Wi…

特発性肺線維症の診断における老化防止タンパク質サーチュイン(Sirt)の標的化 概要

" Targeting anti‐aging protein sirtuin (Sirt) in the diagnosis of idiopathic pulmonary fibrosis SB Shaikh, A Prabhu… - Journal of cellular …, 2019 - Wiley Online Library … approach for IPF. In this prospect, we have discussed the role of S…