AIとIPFと癒しの音楽

特発性肺線維症 idiopathic pulmonary fibrosis (IPF)患者によるIPF関連学術情報の収集とシェア。癒しの音楽もお届けしています。

IPF Weekly Update

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23/03/23

 

[HTML] No increased prevalence of autoantibodies neutralizing type I IFNs in idiopathic pulmonary fibrosis patients

Q Philippot, P Bastard, A Puel, JL Casanova, A Cobat… - Respiratory Research, 2023

… some auto-Abs in IPF patients, we hypothesize that the prevalence of auto-Abs 

neutralizing type I IFNs might be increased in the IPF population and then explained 

specific poor outcome after COVID-19. We screened the plasma of 247 consecutive …

  • 特発性肺線維症患者における I 型 IFN を中和する自己抗体の有病率の増加なし  



Protective role of baicalin in the dynamic progression of lung injury to idiopathic pulmonary fibrosis: A meta-analysis

J Jiang, T Kao, S Hu, Y Li, W Feng, X Guo, J Zeng… - Phytomedicine, 2023

… injury (LI) to idiopathic pulmonary fibrosis (IPF) is a common feature of the 

development of lung disease. At present, effective strategies for preventing this 

progression are unavailable. Baicalin has been reported to specifically inhibit the …

  • 特発性肺線維症への肺損傷の動的進行におけるバイカリンの保護的役割:メタ分析  



[HTML] Geniposide improves bleomycin-induced pulmonary fibrosis by inhibiting NLRP3 inflammasome activation and modulating metabolism

Y Wei, C Liu, L Li - Journal of Functional Foods, 2023

… action in idiopathic pulmonary fibrosis (IPF) have not been well studied. Recent 

studies have found that the progression of IPF is influenced … Gen significantly 

ameliorated pathological injury in the IPF mouse model. Gen reduced the …

  • ジェニポシドは、NLRP3インフラマソームの活性化を阻害し、代謝を調節することにより、ブレオマイシン誘発性肺線維症を改善  



Unsupervised learning for texture based prediction on longitudinal medical imaging data

J Pan - 2023

Idiopathic pulmonary fibrosis (IPF) is a severe and lethal disease. The median 

survival outcome is between 3-5 years for patients without a … In this thesis we 

develop and evaluate a methodology to quantitatively assess changes associated …

  • 縦方向の医用画像データに対するテクスチャ ベースの予測のための教師なし学習   




[HTML] Enhanced immune complex formation in the lungs of patients with dermatomyositis

Y Zaizen, M Okamoto, K Azuma, J Fukuoka, H Hozumi… - Respiratory Research, 2023

… We examined 18 and 19 patients with dermatomyositis-related interstitial lung 

disease and idiopathic pulmonary fibrosis (control), respectively. Lung tissues 

obtained from these patients were semi-quantitatively evaluated by …

  • 皮膚筋炎患者の肺における免疫複合体形成の増強

 

23/03/21

 

[HTML] Pulmonary vessel volume in idiopathic pulmonary fibrosis compared with healthy controls aged> 50 years

J John, AR Clark, H Kumar, AC Vandal, KS Burrowes… - Scientific Reports, 2023

Idiopathic pulmonary fibrosis (IPF) is characterised by progressive fibrosing 

interstitial pneumonia with an associated irreversible decline in lung function and 

quality of life. IPF … to be an independent predictor of mortality in IPF and other …

  • 50歳以上の健康な対照と比較した特発性肺線維症の肺血管容積  



[HTML] A Narrative Review of Real-World Data on the Safety of Nintedanib in Patients with Idiopathic Pulmonary Fibrosis

AJ Podolanczuk, V Cottin - Advances in Therapy, 2023

… Nintedanib is a tyrosine kinase inhibitor approved for the treatment of idiopathic 

pulmonary fibrosis (IPF) and other progressive fibrosing … We review the data from 

all published real-world studies of the safety of nintedanib in patients with IPF. These …

  • 特発性肺線維症患者におけるニンテダニブの安全性に関するリアルワールドデータのナラティブレビュー  



Prognostic value of the qSOFA in patients with acute exacerbation of idiopathic pulmonary fibrosis

R Yamazaki, O Nishiyama, K Yoshikawa, Y Tohda… - Respiratory Investigation, 2023

Idiopathic pulmonary fibrosis (IPF), the most common type of idiopathic interstitial 

pneumonia, is a chronic and progressive lung … idiopathic and triggered AE is 

complicated, we did not examine the causes of AE-IPF in our study. Additionally, the …

  • 特発性肺線維症の急性増悪患者におけるqSOFAの予後的価値   



Prognostic value of deep learning–based fibrosis quantification on chest CT in idiopathic pulmonary fibrosis

JG Nam, Y Choi, SM Lee, SH Yoon, JM Goo, H Kim - European Radiology, 2023

… from chest CT taken from 161 patients diagnosed with idiopathic pulmonary 

fibrosis. … -old man diagnosed with idiopathic pulmonary fibrosis shows extensive 

honeycombing (normal … a 71-year-man with idiopathic pulmonary fibrosis shows …



A novel mutation (p. Y24N) in NHP2 leads to idiopathic pulmonary fibrosis and lung carcinoma chronic obstructive lung disease by disrupting the expression and …

L Liu, Y Sheng, CY Wang, X Liu, T Guo, H Peng, H Luo… - Biochimica et Biophysica …, 2023

Idiopathic pulmonary fibrosis (IPF) is a kind of chronic interstitial lung disease and 

can be caused by mutations in NHP2 ribonucleoprotein … in IPF patients in recent 

years, surpassing that of many types of cancer [3]. However, the pathogenesis and …

  • NHP2 の新規変異 (p.Y24N) は、NHP2 の発現と核細胞質局在を破壊することにより、特発性肺線維症と肺癌慢性閉塞性肺疾患を引き起こす   



Y Li, Y Deng, J He - Medicine, 2023

Idiopathic pulmonary fibrosis (IPF) is a lung disease that is both chronic and 

progressive and is characterized by glycolysis. However, glycolysis’s function and its 

clinical significance in IPF … in glycolysis showing differential expression in …

  • 特発性肺線維症における解糖関連遺伝子の解析に基づく新たな予後指標   



Multiscale SHG/THG analysis of collagen architecture alterations in human idiopathic pulmonary fibrosis tissues and in vitro models (Conference Presentation)

PJ Campagnola, N Sandbo, DS James, E Shelton… - Multiphoton Microscopy in …, 2023

… in idiopathic pulmonary fibrosis (IPF) in human tissues and in vitro models. 

Texture analysis successfully classified the fiber morphology in normal and IPF … 

SHG polarization measurement indicated reduced chirality in the collagen triple …

  • ヒト特発性肺線維症組織および in vitro モデルにおけるコラーゲン構造変化のマルチスケール SHG/THG 解析 (会議発表) 



[PDF] Perioperative pirfenidone treatment as prophylaxis against acute exacerbation of idiopathic

K Sekihara, K Aokage, T Miyoshi, K Tane, G Ishii…

… [Purposes]Lung cancer in patients with idiopathic pulmonary fibrosis (IPF) is 

associated with a … A phase 3 trial of pirfenidone in patients with idiopathic 

pulmonary fibrosis. The … AE-IPF: acute exacerbation of idiopathic pulmonary

  • 特発性疾患の急性増悪に対する予防としての周術期ピルフェニドン治療 



Multiple Fibroblast Subtypes Contribute to Matrix Deposition in Pulmonary Fibrosis

X Liu, K Dai, X Zhang, G Huang, H Lynn, A Rabata… - American Journal of …, 2023

… We identified and confirmed the novel fibroblast subtypes we reported recently 

across all samples of both mouse models and human lung fibrotic diseases 

including idiopathic pulmonary fibrosis, systemic sclerosis associated interstitial lung …

  • 複数の線維芽細胞サブタイプが肺線維症におけるマトリックス沈着に寄与する 



[HTML] Telomere length associates with chronological age and mortality across racially diverse pulmonary fibrosis cohorts

A Adegunsoye, CA Newton, JM Oldham, B Ley, CT Lee… - Nature Communications, 2023

… (PF) is a complex group of lung diseases characterized by scarring in the 

interstitium of the lung; median survival in its most common subtype, idiopathic PF (IPF), 

is only 3–5years 1,2,3 . While numerous investigations over the past decade have …

  • テロメアの長さは、人種的に多様な肺線維症コホート全体の実年齢および死亡率と関連しています




 

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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。

当面、毎週アラートの内容をアップしていこうと思います。

 

癒しの音楽をお届けいたします。 

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