ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です！と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この１年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。
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23/06/08
[PDF] The application of metabolomics toward idiopathic pulmonary fibrosis and potential metabolomic value of diverse samples in interstitial lung diseases
M Liu, ZJ Cheng, M Xue, R Lin, T Zhang, B Sun - Precision Medical Sciences, 2023
… , idiopathic pulmonary fibrosis (IPF) is one of the most prevalent, contributing substantially to morbidity and mortality. However, IPF is … The potential value of metabolomics in idiopathic lung disease (ILD), especially in idiopathic pulmonary …
[PDF] Progressive Pulmonary Fibrosis: Lumping together of the progressive phenotype!!
A Parekh, S Singhal - National Medicos Organisation Journal (एन एम ओ …, 2023
… Among the IIPSs, idiopathic pulmonaryfibrosis is a fibrotic phenotype with rapid progression and poor prognosis. Based on the results … patients with Idiopathic PulmonaryFibrosis [6-8]. However, it was later realized that a subset of IIPs other …
- 進行性肺線維症: 進行性の表現型がまとまって発生!!
[PDF] Macrophage‐based delivery of anti‐fibrotic proteins alleviates bleomycin‐induced pulmonary fibrosis in mice
H Liu, C Yang, Y Gao, X Zhang, M Wang, X Yu… - … & Translational Medicine, 2023
… Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease characterized by chronic, progressive, and fibrotic lung injury. Although remarkable progress has been made toward understanding the pathogenesis of PF, finding more effective …
- マクロファージによる抗線維化タンパク質の送達は、ブレオマイシン誘発マウスの肺線維症を軽減
23/06/06
[PDF] Current Insights into the Role of Antifibrotic Drugs in the Management of Idiopathic Pulmonary Fibrosis (IPF)
VM Thorat, PS Salve, SA Surale-Patil
… Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease that is chronic and progressive and is characterized by an excessive … , is the main emphasis of IPF care. Current information on the use of antifibrotic medications in the treatment of …
- 特発性肺線維症（IPF）の管理における抗線維化薬の役割に関する最新の洞察
Network pharmacology and molecular docking to explore the pharmacological mechanism of Yifei Tongluo granules in treating idiopathic pulmonary fibrosis: A review
Y Hou, G Wang, S Han, H Liu, X Jia - Medicine, 2023
… regulates relevant biological processes to intervene in IPF. This study shows that YTG can treat IPF by inhibiting the epithelial-mesenchymal … YTG can be widely used as an adjuvant therapy for IPF in clinical practice, and this study provides the …
- 特発性肺線維症の治療におけるYifei Tongluo顆粒の薬理学的メカニズムを探索するためのネットワーク薬理学と分子ドッキング：レビュー
Structured exercise training in patients with idiopathic pulmonary fibrosis
T Wallis - 2023
… Idiopathic pulmonary fibrosis (IPF) is the prototypic progressive fibrotic lung disease and is … Exercise training is recommended for patients with IPF with evidence that it leads to short-… training programme (SRETP) in patients with IPF …
- 特発性肺線維症患者における体系的な運動トレーニング
[PDF] Terapeutic Remission of Community Acquired Pneumonia Caused by Rothia Mucilaginosa in an Adult Patient with Idiopathic Pulmonar Fibrosis
SNN Christo, GAA de Jesus, BCR Jesus - American Journal of Internal Medicine, 2023
… We present the case of a 50-year-old adult patient, without neutropenia, without hematological malignancy, with progressive idiopathic pulmonary fibrosis (IPF) of 1 … A 50 years old male, having a diagnosis of idiopathic pulmonary fibrosis a year ago …
- 特発性肺線維症の成人患者におけるロチア・ムシラギノーサによる市中肺炎の治療的寛解
Chronic pulmonary fibrosis alters the functioning of the respiratory neural network
CH Yegen, D Marchant, JF Bernaudin, C Planes… - Frontiers in Physiology
… Some patients with idiopathic pulmonaryfibrosis present impaired ventilatory variables … The lung stiffness observed in pulmonaryfibrosis may also have an effect on the functioning … To this end, we sought to uncover the consequences of …
- 慢性肺線維症は呼吸神経ネットワークの機能を変化させる
[HTML] Respiratory and non-respiratory symptoms in patients with IPF or sarcoidosis and controls
AEM Bloem, S Houben-Wilke, RLM Mostard, N Stoot… - Heart & Lung, 2023
… Besides dyspnoea and cough, patients with idiopathic pulmonary fibrosis (IPF) or sarcoidosis may experience distressing non-respiratory symptoms, such as fatigue or muscle weakness. However, whether and to what extent symptom burden differs …
- IPFまたはサルコイドーシス患者および対照患者における呼吸器症状および非呼吸器症状
Prevalence of diaphragm dysfunction in patients with interstitial lung disease (ILD): The role of diaphragmatic ultrasound
N Bernardinello, E Cocconcelli, A Boscolo, G Castelli… - Respiratory Medicine, 2023
… patients with COPD, pulmonary fibrosisassociated with emphysema (CPFE), and idiopathic pulmonary fibrosis (IPF), the presence of … ), including Connective Tissue Disease-associated ILD (CTD-ILD) and IPF, are scarce. In one such study in patients …
- 間質性肺炎 (ILD) 患者における横隔膜機能不全の有病率: 横隔膜超音波の役割
[HTML] Identification of paired-related Homeobox Protein 1 as a key mesenchymal transcription factor in pulmonary fibrosis
E Marchal-Duval, M Homps-Legrand, A Froidure… - eLife, 2023
… Matrix remodeling is a salient feature of idiopathic pulmonary fibrosis (IPF). Targeting cells driving matrix remodeling could be a promising avenue for IPF treatment. Analysis of transcriptomic database identified the mesenchymal …
- 肺線維症における重要な間葉転写因子としてのペア関連ホメオボックスタンパク質 1 の同定
23/06/02
[PDF] Searching for Novel Candidate Small Molecules for Ameliorating Idiopathic Pulmonary Fibrosis: a Narrative Review
K Kim, R Hossain, X Li, HJ Lee, CJ Lee - Biomolecules & Therapeutics, 2023
… The strategy for the development of a novel therapeutic agent eradicating the core of the disease and/or managing the clinical symptoms of pulmonary fibrosis. We tried to find a potential of managing the clinical symptoms of idiopathic …
- 特発性肺線維症を改善するための新規候補小分子の探索: 物語的レビュー
[HTML] Economic Burden of Idiopathic Pulmonary Fibrosis in Spain: A Prospective Real-World Data Study (OASIS Study)
MJ Rodríguez-Nieto, E Cano-Jiménez… - PharmacoEconomics, 2023
Background Idiopathic pulmonary fibrosis(IPF) is a progressive and fatal lung disease associated with dyspnoea, cough and impaired quality of life affecting around 7500 patients in Spain. Objective Our aim was to estimate the economic …
- スペインにおける特発性肺線維症の経済的負担: 前向きの実世界データ研究 (OASIS 研究)
[HTML] Exploratory phase 2 study of the novel oral multi-kinase inhibitor TAS-115 in patients with idiopathic pulmonary fibrosis
Y Nishioka, S Homma, T Ogura, S Sato, N Arai, K Tomii… - Respiratory Investigation, 2023
… Idiopathic pulmonary fibrosis (IPF) is the most common type of idiopathic interstitial pneumonia, showing chronic, progressive fibrogenesis in the lungs [1,2]. The incidence of IPF has been reported to be 2.8–18 per 100,000 worldwide [[1], [2], [3]] …
- 特発性肺線維症患者を対象とした新規経口マルチキナーゼ阻害剤TAS-115の探索的第2相試験
Idiopathic Pulmonary Fibrosis Misdiagnosed as Sputum-Negative Tuberculosis
A Khan, JL Ferrero - The Misdiagnosis Casebook in Clinical Medicine: A …, 2023
… Idiopathic pulmonary fibrosis (IPF) is a devastating pulmonary disease characterized by … Idiopathic pulmonary fibrosis (IPF) is an ILD with an unknown underlying cause characterized … Regardless of the numerous advancements in …
- 特発性肺線維症が喀痰陰性結核と誤診される
Variations in mechanical stiffness alter microvascular sprouting and stability in a PEG hydrogel model of idiopathic pulmonary fibrosis.
J Leonard-Duke, AC Bruce, SM Peirce, LJ Taite - Microcirculation (New York, NY …, 2023
Objective Microvascular remodeling is governed by biomechanical and biochemical cues which are dysregulated in idiopathic pulmonaryfibrosis. Understanding how these cues impact endothelial cell-pericyte interactions necessitates a model system …
- 機械的剛性の変化により、特発性肺線維症のPEGヒドロゲルモデルにおける微小血管の発芽と安定性が変化します。
Interstitial lung disease: a decade of progress and hope
A Adegunsoye - The Lancet Respiratory Medicine, 2023
… Pulmonary fibrosis, a progressive form of ILD, is characterised by inflammation and fibrosis of the lung parenchyma. 1 Among ILDs, idiopathic pulmonary fibrosis (IPF) … 5, 6 Two novel antifibrotic therapies, nintedanib and pirfenidone, have transformed …
- 間質性肺炎: 進歩と希望の 10 年
23/06/01
[PDF] Influence of miR-142-3p on Pulmonary Fibrosis Through Regulation of p53/NF-κB
Y Sen, HJ Li, K Zhang, SQ Li, YG Xu - Journal of Pharmacology and …, 2023
… bleomycin-induced idiopathic pulmonaryfibrosis (IPF) mouse model … , IPF mainly occurs in the elderly, and the incidence of IPF is positively correlated with age. Damage to alveolar epithelial cells (AECs) is known to play a critical role in the …
- p53/NF-κBの制御を介した肺線維症に対するmiR-142-3pの影響
An Adult Case of Idiopathic Pulmonary Hemosiderosis Associated with Pulmonary Fibrosis and Emphysematous Change
K Masato, O Yuiko, K Megumi, H Ryutaro, T Kenichiro… - Japanese Journal of …, 2023
… This patient was diagnosed with idiopathicpulmonary hemosiderosis (IPH) that progressed to end-stage pulmonary fibrosis despite treatment. Autopsy demonstrated DAH with pulmonary fibrosis and emphysematous change …
- 肺線維症と気腫性変化を伴う特発性肺ヘモジデラ症の成人例
Plasma Wnt7b Protein in Rheumatoid Arthritis: Detection of Interstitial Lung Disease
M Rabie, HI Abd El-Hady, DA Ibrahim, TH Hassan… - Immunobiology, 2023
… (RA) patients (with and without interstitial lung disease (ILD)) and in idiopathic pulmonaryfibrosis (IPF) patients and its relationship with RA disease activity and/or severity of pulmonaryfibrosis. To assess the validity of plasma Wnt7b for the …
- 関節リウマチにおける血漿 Wnt7b タンパク質: 間質性肺疾患の検出
Exosomal miR-218 derived from mesenchymal stem cells inhibits endothelial-to-mesenchymal transition by epigenetically modulating of BMP2 in pulmonary fibrosis
Y Zhao, L Du, J Sun, X Wang, Z Cong, S Chen, F Wang… - Cell Biology and Toxicology, 2023
… phenotypes, participates in the pathogenic mechanism of idiopathic pulmonary fibrosis. Recently, exosomes derived from human umbilical cord … -Exo in pulmonary fibrosis. The intravenous administration of hucMSC-Exos alleviated …
- 間葉幹細胞由来のエキソソーム miR-218 は肺線維症における BMP2 をエピジェネティックに調節することにより内皮から間葉への移行を阻害する
23/05/30
Chronic Expression of a Clinical SFTPC Mutation Causes Murine Lung Fibrosis with Idiopathic Pulmonary Fibrosis Features.
L Rodriguez, Y Tomer, P Carson, T Dimopoulos… - American Journal of …, 2023
… , a feature of the IPF lung (26), and then sought to analyze the BALF for the presence of known IPF biomarkers. The profibrotic protein Osteopontin (SPP1) and the matrix metalloproteinase MMP7 have been shown to differentiate IPF from other …
- 臨床的 SFTPC 変異の慢性発現は、特発性肺線維症の特徴を伴うマウス肺線維症を引き起こします。
[PDF] Exploration of the shared genes and signaling pathways between lung adenocarcinoma and idiopathic pulmonary fibrosis
H Li, W Wang, Z Huang, P Zhang, L Liu, X Sha, S Wang… - 2023
Background: Idiopathic pulmonary fibrosis(IPF), a type of interstitial lung disease (ILD), is a chronic disease with an unknown etiology. The occurrence of lung cancer (LC) is one of the main causes of death in patients with IPF. However, the pathogenesis …
- 肺腺癌と特発性肺線維症の間の共通遺伝子とシグナル伝達経路の探索
Chinese Herbal Medicine for Idiopathic Pulmonary Fibrosis: An Overview of Systematic Review.
M Li, R Wu, Y Zhao, L Li, G Li, S Liu, H Li - Alternative Therapies in Health and …, 2023
… Herbal Medicines (CHMs) for IdiopathicPulmonary Fibrosis (IPF) and provide high-level … Published SRs and meta-analyses evaluating CHM use in IPF and reporting clinically-relevant … CHM has potential benefits for patients with IPF …
- 特発性肺線維症に対する漢方薬：系統的レビューの概要。
[PDF] Evaluation of Brilaroxazine (RP5063) in a Bleomycin-Induced Rodent Model of Idiopathic Pulmonary Fibrosis
L Bhat, MC Nault, SR Bhat, M Biernat, SM Labbe - Medical Research Archives, 2023
Idiopathic pulmonary fibrosis pathology involves serotonin (5-HT), with an increased expression of 5-HT 2A/2B/7 receptors in the lungs. This study tests the hypothesis that brilaroxazine (RP5063), an agent with a potent binding affinity for serotonin 5-HT …
- 特発性肺線維症のブレオマイシン誘発齧歯動物モデルにおけるブリラロキサジン (RP5063) の評価
Elderly idiopathic pulmonary fibrosis patients remain on therapy despite higher incidence of adverse events and dose reductions
A Cilli, N Ocal, F Uzer, F Coskun, C Sevinc, A Ursavas… - Respiratory Investigation, 2023
… Idiopathic pulmonary fibrosis (IPF) predominantly affects people over the age of 60 years and its incidence increases with age. Limited data is available on the use of antifibrotics in the elderly IPF … Idiopathicpulmonary fibrosis (IPF) is a chronic …
- 高齢の特発性肺線維症患者は、有害事象の発生率が高く、用量が減量されているにもかかわらず、治療を続けている
[PDF] The experiences of patients with idiopathic pulmonary fibrosis: A descriptive review
T Cen, S Yang - 2023
… Background: Idiopathic pulmonary fibrosiswas previously considered a rare disease, but now … of the study was to describe the experiences of patients with idiopathicpulmonary fibrosis. … study was to describe the experiences of patients …
- 特発性肺線維症患者の経験: 記述的レビュー
[PDF] Modern Concepts of Idiopathic Pulmonary Fibrosis
OA Zokirovna - American Journal of Pediatric Medicine and Health …, 2023
… Idiopathic pulmonary fibrosis (IPF) is a specific form of chronic lung disease characterized by progressive fibrosis of the lung tissue, an … IPF is the most common form of idiopathic interstitial pneumonia (IIP). According to modern registries …
- 特発性肺線維症の現代の概念
Corrigendum: BI 1015550 is a PDE4B inhibitor and a clinical drug candidate for the oral treatment of idiopathic pulmonary fibrosis
FE Herrmann, C Hesslinger, L Wollin, P Nickolaus - Frontiers in Pharmacology
Corrigendum on: Herrmann FE, Hesslinger C, Wollin L, Nickolaus P. BI 1015550 is a PDE4B inhibitor and a clinical drug candidate for the oral treatment of idiopathic pulmonary fibrosis. Front Pharmacol 2022; 13: 838449. doi: 10.3389/fphar …
- 訂正事項: BI 1015550 は PDE4B 阻害剤であり、特発性肺線維症の経口治療の臨床薬候補です
Is there a role for specialized pro-resolving mediators in pulmonary fibrosis?
TH Thatcher, MAT Freeberg, YPA Myo, PJ Sime - Pharmacology & Therapeutics, 2023
… culture and animal models of pulmonaryfibrosis, and we will consider future therapeutic implications of SPMs in fibrosis. … idiopathicpulmonary fibrosis (IFP), progressive scarring of the lung can lead to respiratory failure and even death …
- 肺線維症において特殊な解決促進メディエーターの役割はあるのでしょうか?
The relationship between gastro-oesophageal reflux and pulmonary fibrosis: a never-ending story
M Molina-Molina - European Respiratory Journal, 2023
… Factors involved in the relationship between idiopathic pulmonary fibrosis (IPF) and gastro-oesophageal reflux disease (GORD). The … . The interplay of the genetic architecture, aging, and environmental factors in the pathogenesis of …
- 胃食道逆流症と肺線維症の関係: 終わりのない物語
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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
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