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特発性肺線維症 idiopathic pulmonary fibrosis (IPF)患者によるIPF関連学術情報の収集とシェア。癒しの音楽もお届けしています。

IPF Weekly Update

ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です!と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この1年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。

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23/06/17

 

Y Lin, X Lai, T Lei, Y Qiu, Q Deng, Q Liu, Z Wang… - Journal of Inflammation …, 2023

Idiopathic pulmonary fibrosis (IPF) is a disease with unclear etiology and a poor prognosis. Although the involvement of neutrophils in IPFIdiopathic pulmonaryfibrosis (IPF) is a chronic and progressive interstitial lung disease characterized by …

  • 特発性肺線維症における好中球関連遺伝子発現サイン:疾患の特徴と診断ハブ遺伝子の同定への影響   



Contributing factor for the pirfenidone dose reduction in patients with idiopathic interstitial pneumonia in real-world settings—A dose-specific analysis

Y Takeshita, N Sugimoto, K Kobayashi, H Toyota, A Ito… - 2023

Idiopathic pulmonary fibrosis (IPF) is a disease with a poor prognosis and a median survival time (MST) from the diagnosis of 35 months, … Effects of low-dose pirfenidone on survival and lung function decline in patients with idiopathic

  • 現実世界の特発性間質性肺炎患者におけるピルフェニドン用量減量の寄与因子—用量特異的分析   



Interstitial Lung Diseases

R Abrencillo, IC Mira-Avendano, RM Estrada-Y-Martin… - The Thorax: Medical …, 2023

Idiopathic pulmonary fibrosis (IPF) is the most common form of idiopathic interstitial pneumonias [3]. Estimates of the true incidence and prevalence of IPFIPF also appears to be more common in men and rare in individuals below the age …

  • 間質性肺疾患   



[HTML] Reciprocal interactions between alveolar progenitor dysfunction and aging promote lung fibrosis

G Huang, X Liu, N Liu, F Taghavifar, K Dai, C Yao… - eLife, 2023

idiopathic pulmonary fibrosis (IPF). Dysfunction and loss of type 2 alveolar epithelial cells (AEC2s) with failed regeneration is a seminal causal event in the pathogenesis of IPF, … the interactions between aging and lung injury with …

  • 肺胞前駆細胞の機能不全と老化の相互作用が肺線維症を促進  



Low-dose vanadium pentoxide perturbed lung metabolism associated with inflammation and fibrosis signaling in male animal and in vitro models

X He, ZR Jarrell, MR Smith, VLT Ly, X Hu… - American Journal of …, 2023

… Alterations in lipid metabolism included leukotrienes and prostaglandins involved in 28 inflammatory signaling, which have been associated with the pathogenesis of idiopathic29 pulmonary fibrosis (IPF) and other disease processes. Elevated …

  • 低用量の五酸化バナジウムは、雄の動物モデルおよび in vitro モデルにおける炎症および線維症シグナル伝達に関連する肺代謝を混乱させた   





23/06/15

 

SPECT Imaging of Lysyl Oxidase-like 2 in a Model of Idiopathic Pulmonary Fibrosis

R Vizier, AR Garnier, A Dias, M Moreau, M Claron… - Molecular Pharmaceutics, 2023

Idiopathic pulmonary fibrosis (IPF) is a chronic and irreversible lung disease characterized by an alteration of the pulmonary architecture, … progress, IPF diagnosis is still difficult. While a standard high-resolution computed tomography (HRCT) …

  • 特発性肺線維症モデルにおけるリシルオキシダーゼ様 2 の SPECT イメージング   



Customizable Resveratrol Spray-dried Micro-composites for Inhalation as a Promising Contender for Treatment of Idiopathic Pulmonary Fibrosis

S Ahmed, M Mansour, RAH Ishak, ND Mortada - International Journal of …, 2023

… The past decades have witnessed tremendous expansion in utilization of plant-derived medicines as resveratrol (RES) in treating several diseases like idiopathicpulmonary fibrosis (IPF). RES can exhibit its role in treating IPF via its outstanding …

  • 特発性肺線維症治療の有望な候補としての吸入用のカスタマイズ可能なレスベラトロール噴霧乾燥マイクロ複合材料   



Ultrasound evaluation of diaphragmatic function in patients with idiopathic pulmonary fibrosis: a retrospective observational study

J Milesi, A Boussuges, P Habert, J Bermudez… - 2023

… We retrospectively included idiopathicpulmonary fibrosis (IPF) patients followed in our center (Marseille, France) between January 2020 and February 2023 who underwent diaphragmatic ultrasound. Our objectives were to describe the …

  • 特発性肺線維症患者における横隔膜機能の超音波評価:後ろ向き観察研究   



A case of welder's lung with end-stage pulmonary fibrosis

X Baur - Pneumologie, 2023

… Conclusion In the absence of a systemic disorder and the failure to meet the criteria for diagnosis of idiopathic pulmonary fibrosis(IPF), … The statutory accident insurance institution had denied acceptance of an occupational disease by …

  • 末期肺線維症を伴う溶接工肺の1例   



Efficacy and safety of antifibrotic agents in the treatment of CTD-ILD and RA-ILD: A systematic review and meta-analysis

M Yang, YQ Wu, XM Liu, C Zhao, T Li, TQ Li, XW Zhang… - Respiratory Medicine, 2023

… antifibrotics in idiopathic pulmonaryfibrosis. This study … Idiopathic pulmonaryfibrosis (IPF) is considered a common and classical progressive fibrosing ILD in a non-autoimmune form. Two antifibrotic agents have received marketing approval as …

  • CTD-ILD および RA-ILD の治療における抗線維化剤の有効性と安全性:系統的レビューとメタ分析 



[PDF] Covid19 Vaccine Induced Interstitial Lung Disease

AJ Cincotta - J Clin Nur Rep 2 (2), 01, 2023

… , including those of unknown etiology such as idiopathic pulmonary fibrosis (IPF), [1]. … This is typically a progressive disorder of lung scarring, best known as pulmonary fibrosis. As … When the origin cannot be found it is called idiopathic pulmonary



23/06/13

 

Lipid metabolism in idiopathic pulmonary fibrosis: From pathogenesis to therapy

R Chen, J Dai - Journal of Molecular Medicine, 2023

Idiopathic pulmonary fibrosis (IPF) is a chronic irreversible interstitial lung disease … etiology of IPF is unknown, which poses a significant challenge to the treatment of IPF. Recent studies have identified a strong association between lipid metabolism …

  • 特発性肺線維症における脂質代謝:病因から治療まで   



[PDF] The association between idiopathic pulmonary fibrosis and diabetes mellitus: a clinical retrospective study

T Ji, R Chen, G Zhong, W Lyu, Q Xu, H Jiang, Y Gao… - 2023

idiopathic pulmonary brosis (IPF) remains uncertain. In this study, we aimed to determine the prevalence of DM in IPF and whether DM is associated with survival in IPF… in IPF patients, and whether DM affected the outcomes of IPFpatients …

  • 特発性肺線維症と糖尿病の関連性:臨床遡及研究   






“The will to live!” The perceptions of patients with idiopathic pulmonary fibrosis in relation to antifibrotic treatment: a qualitative study

LN Generoso, MG Assis, PLB de Leucas, MB Luz… - 2023

… Patients with idiopathic pulmonary fibrosis(IPF) are typically treated with antifibrotic drugs, which act by slowing the progression of the disease, thus reducing the frequency of … In this study, we discuss the perceptions of individuals with IPF in …

  • 「生きる意志!」 抗線維化治療に対する特発性肺線維症患者の認識:定性的研究   



Endothelial cells in pulmonary fibrosis: more than a bystander

T Yanagihara, C Guignabert, MRJ Kolb - European Respiratory Journal, 2023

… , resulting in a significant contribution to the pathogenesis of pulmonary fibrosis, and this process is redirected through induction of FoxA2 https://bit.ly/3YQvSIX Pulmonary fibrosis, including idiopathic pulmonary fibrosis (IPF), is a debilitating and …

  • 肺線維症における内皮細胞:単なる傍観者ではない   

 

 

 

[HTML] Targeting pathogenic macrophages by the application of SHP-1 agonists reduces inflammation and alleviates pulmonary fibrosis

SY Hong, YT Lu, SY Chen, CF Hsu, YC Lu, CY Wang… - Cell Death & Disease, 2023

Idiopathic pulmonary fibrosis is a progressive fibrotic disorder with no cure that is characterized by deterioration of lung … of pulmonary fibrosis. Herein, we investigated whether employing a SHP-1 agonist ameliorates pulmonary fibrosis in …

  • SHP-1 アゴニストの適用による病原性マクロファージの標的化は炎症を軽減し、肺線維症を軽減します   



Geranylgeranylacetone, an inducer of heat shock protein 70, attenuates pulmonary fibrosis via inhibiting NF-κB/NOX4/ROS signalling pathway in vitro and in vivo

R Zhou, C Jin, L Jiao, S Zhang, M Tian, J Liu, S Yang… - Chemico-Biological …, 2023

… In this study, the results suggested that HSP70 may be a potential therapeutic target for idiopathic pulmonary fibrosis. However, further research is needed to determine whether this target will affect pulmonary fibrosis through other signaling pathways. …

  • 熱ショックタンパク質 70 の誘導物質であるゲラニルゲラニルアセトンは、インビトロおよびインビボで NF-κB/NOX4/ROS シグナル伝達経路を阻害することで肺線維症を軽減します   



Association between Parenchymal B-Cell Follicles and CT-Proven Enlarged Mediastinal Lymph Nodes in Patients with Pulmonary Fibrosis.

S Kronborg-White, E Bendstrup, LB Madsen… - … ; International Review of …, 2023

… Mediastinal lymph node enlargement (MLNE) is a finding described in a subset of patients with idiopathic pulmonary fibrosis (IPF) and other … between MLNE and B-cell follicles in lung tissue, another aspect detectable in the lung tissue of patients with …

  • 肺線維症患者における実質B細胞濾胞とCTで証明された縦隔リンパ節の拡大との関連。   



[HTML] Acute exacerbation of interstitial lung disease in the intensive care unit: Principles of diagnostic evaluation and management

MKH Syed, O Bruck, A Kumar, S Surani - World Journal of Critical Care Medicine, 2023

… with idiopathic pulmonary fibrosis with usual interstitial pneumonia pattern; B: A 54-year-old male with non-specific interstitial pneumonia. Chest CT showed faint ground glass opacity and mild reticulations (non-specific interstitial pneumonia); C: Idiopathic

  • 集中治療室における間質性肺疾患の急性増悪: 診断評価と管理の原則  



23/06/10

 

[PDF] Oral Health and Wellbeing of Patients with Idiopathic Pulmonary Fibrosis

A Barczyk, A Białas, W Piotrowski, S Kłosek… - 2023

Idiopathic pulmonary fibrosis (IPF) is the most common type of idiopathic interstitial … Many risk factors for IPF have been identified, with male gender and smoking being the most … An inevitable adverse prognosis in IPF is mostly due to limited …

  •  特発性肺線維症患者の口腔の健康と幸福   



Changes in patient-reported outcomes in patients with non-idiopathic pulmonary fibrosis fibrotic interstitial lung disease and progressive pulmonary fibrosis

R Takei, T Matsuda, J Fukihara, H Sasano, Y Yamano… - Frontiers in Medicine

… However, little is known about how HRQoL changes in patients with non-idiopathicpulmonary fibrosis (IPF) FILD, especially in those with progressive pulmonary fibrosis(PPF). The aim of this study is to clarify whether HRQoL deteriorates in …

  • 非特発性肺線維症、線維性間質性肺疾患および進行性肺線維症の患者における患者報告転帰の変化   



[HTML] Impact of partial pressure of arterial oxygen and radiologic findings on postoperative acute exacerbation of idiopathic interstitial pneumonia in patients with lung …

Y Azuma, S Sakamoto, S Homma, T Sakai, S Koezuka… - Surgery Today, 2023

… Among the classifications of ILD, idiopathicinterstitial pneumonia (IIP) including idiopathicpulmonary fibrosis (IPF) is the most frequent, … infiltrates during the chronic course of IPF, a concept identified first in Japan [4]. To date, AE of IPF has …

  • 肺癌患者における特発性間質性肺炎の術後急性増悪に対する動脈血酸素分圧と放射線所見の影響   



[HTML] Pharmacological inhibition of MDM4 alleviates pulmonary fibrosis

Q Mei, Z Yang, Z Xiang, H Zuo, Z Zhou, X Dong… - Theranostics, 2023

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease of unknown etiology … will benefit the development of effective therapies for IPF. We previously reported that MDM4 … Human idiopathicpulmonary fibrosis (IPF) is a …

  • MDM4 の薬理学的阻害は肺線維症を軽減します   

 

 

 

 

 

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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。

当面、毎週アラートの内容をアップしていこうと思います。

 

癒しの音楽をお届けいたします。 

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