ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です！と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この１年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。
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23/11/11
Assessment and Management of Cough in Idiopathic Pulmonary Fibrosis: A Narrative Review
S Liu, X Ye - Lung, 2023
… with IPF-related cough [11], it was observed that 31% of IPF patients exhibited a notable reduction in day time cough frequency. Conversely, in patients with chronic idiopathic… This suggests that the etiology of IPF cough and chronic cough may not …
- 特発性肺線維症における咳の評価と管理: 解説レビュー
[HTML] Effects of comorbid chronic kidney disease on mortality in idiopathic pulmonary fibrosis patients and influence of pirfenidone
YS Jo, KJ Kim, CK Rhee, YH Kim - Scientific Reports, 2023
… in idiopathic pulmonary fibrosis (IPF), and managing IPF with CKD is challenging due to limited options for antifibrotic therapy. The aim of this study was to examine the prevalence of CKD and prescription status of pirfenidone in IPF … IPF and CKD …
- 特発性肺線維症患者の死亡率に対する慢性腎臓病の合併の影響とピルフェニドンの影響
Effects of short-term air pollution exposure on symptoms development in the course of idiopathic pulmonary fibrosis
K Dimakopoulou, I Tomos, ED Manali, SA Papiris… - Expert Review of …, 2023
… of idiopathic pulmonary fibrosis (IPF) representing also a significant risk factor for the development of acute exacerbation of IPF (AE-IPF), a … IPF represents a chronic and irreversibly progressive interstitial lung disease with an ominous prognosis [Citation10] …
- 特発性肺線維症の経過における症状発現に対する短期大気汚染曝露の影響
Efficacy and safety of Kangxian Huanji Granule as adjunctive treatment in acute exacerbation of idiopathic pulmonary fibrosis: an exploratory randomized controlled …
J Li, H Zhang, W Guo, L Wang, D Zhang, L Zhao… - Journal of Integrative …, 2023
… Acute exacerbation of idiopathic pulmonaryfibrosis (AE-IPF) is an important occurrence in the natural history of idiopathic pulmonaryfibrosis (IPF), associated with … At present, there is no effective treatment for AE-IPF. Chinese herbal …
- 特発性肺線維症の急性増悪における補助治療としての康仙黄基顆粒の有効性と安全性：探索的ランダム化対照試験
[HTML] Signs of Alveolar Collapse in Idiopathic Pulmonary Fibrosis, Hypersensitivity Pneumonitis and Systemic Sclerosis Revealed by Inspiration and Expiration Computed …
MF Wittwer, SY Kim, A Leichtle, S Berezowska… - BioMed, 2023
… According to our study, not only patients with idiopathic pulmonary fibrosis (IPF) but also those with hypersensitivity pneumonitis (HP) exhibit a greater increase in expiratory density in the non-fibrotic appearing lung tissue compared to healthy …
- 特発性肺線維症、過敏性肺炎、全身性硬化症における肺胞虚脱の兆候が吸気および呼気コンピュータ断層撮影によって明らかに
[HTML] Collagen type XIV is proportionally lower in the lung tissue of patients with IPF
M Nizamoglu, ML Koloko Ngassie, RA Meuleman… - Scientific Reports, 2023
… Abnormal deposition of extracellular matrix (ECM) in lung tissue is a characteristic of idiopathic pulmonary fibrosis (IPF). Increased collagen deposition is also accompanied by altered collagen organization. Collagen type XIV, a fibril-associated …
- IPF患者の肺組織ではXIV型コラーゲンが比例して低下している
Vanadium Carbide Nanosheets with Broad-Spectrum Antioxidant Activity for Pulmonary Fibrosis Therapy
Q Liu, Y Ren, H Jia, H Yuan, Y Tong, S Kotha, X Mao… - ACS nano, 2023
… Idiopathic pulmonary fibrosis is a chronic and highly lethal lung disease that largely results … as a potential antioxidant for treatment of pulmonary fibrosis by scavenging reactive oxygen and … Idiopathic pulmonary fibrosis(IPF) is a chronic …
- 肺線維症治療のための広範囲の抗酸化活性を有する炭化バナジウムナノシート
Genetic deficiency of the transcription factor NFAT1 confers protection against fibrogenic responses independent of immune influx
R Vittal, NM Walker, APP McLinden, RR Braeuer, F Ke… - American Journal of …, 2023
… first assessed NFAT1 expression in human IPF lung tissues and mesenchymal cells (MCs) … NFAT1 in control and IPF cells with increased nuclear concentration in IPF. NFAT1 activation … a useful tool to investigate treatment options for …
- 転写因子NFAT1の遺伝的欠損により、免疫流入とは独立して線維形成反応に対する防御が与えられる
[PDF] PGF2α signaling drives fibrotic remodeling and fibroblast population dynamics in mice
LR Rodriguez, SY Tang, WR Barboza, A Murthy… - JCI insight, 2023
… Idiopathic Pulmonary Fibrosis (IPF) is a chronic parenchymal lung disease characterized by repetitive alveolar cell injury, myofibroblast proliferation, and excessive extracellular matrix deposition for which unmet need persists for effective …
- PGF2αシグナル伝達はマウスの線維性リモデリングと線維芽細胞集団の動態を促進
23/11/09
Association of the lung immune prognostic index with the survival of patients with idiopathic interstitial pneumonias
T Suzuki, M Karayama, Y Aoshima, K Mori… - Respirology, 2023
… had idiopathic pulmonary fibrosis [IPF], and 301 and 255 had non-IPF, respectively). In the exploratory cohort, patients with IPF and a low … In the current study, a high LIPI was associated with a poor prognosis in patients with IPF, but not …
- 肺免疫予後指数と特発性間質性肺炎患者の生存との関連
Increased Expression of CXCL6 in Secretory Cells Drives Fibroblast Collagen Synthesis and is Associated With Increased Mortality in Idiopathic Pulmonary Fibrosis.
H Bahudhanapati, J Tan, RM Apel, B Seeliger… - The European Respiratory …, 2023
… Recent data suggest that the localization of airway epithelial cells in the distal lung in idiopathic pulmonary fibrosis (IPF) may drive … IPF patients and air-liquid interface (ALI) cultures. We employed ex vivo donor and IPFlung fibroblasts and an …
- 分泌細胞におけるCXCL6の発現増加は線維芽細胞のコラーゲン合成を促進し、特発性肺線維症の死亡率の増加と関連しています。
Arrhythmia Burden, Associated Outcomes, and Cost Implications in Patients Hospitalized With Idiopathic Pulmonary Fibrosis
P Benjamin, O Oyenubi, B Gitler, AC Stan, J ROBLES - Circulation, 2023
… of idiopathic pulmonary fibrosis (IPF), however, associated costs and hospital outcomes are unknown. We aim to determine the impact of cardiac arrhythmias on outcomes and costs among hospitalized IPF … IPF-associated hospitalizations with …
[PDF] Differentiating Connective Tissue Disease-Associated Interstitial Lung Disease from Idiopathic Pulmonary Fibrosis Using CT Characteristics of the usual Interstitial …
RAJ Abdulazeez, FA Albaghdadi, SG Shati
… This finding is consistent with the fact that IPFis a disease that primarily affects older adults. Our findings are consistent with a study done by [14], which revealed IPF is a form of interstitial lung disease that primarily affects older people. IPF is …
- CT を使用した結合組織病関連間質性肺疾患と特発性肺線維症の鑑別 通常の間質性肺炎パターンの特徴
Identification and Validation of Genes Exhibiting Dynamic Alterations in Response to Bleomycin-Induced Pulmonary Fibrosis
D Li, J Wang, J Zeng, S Li, D Sun, L Qiu, Z Huang… - Molecular Biotechnology, 2023
… Idiopathic pulmonary fibrosis (IPF) carries a high mortality rate and has a poor prognosis. The pathogenesis of pulmonary fibrosis (PF) is … The results will provide therapeutic targets for patients suffering from IPF. Whole transcriptomic profiles of …
- ブレオマイシン誘発性肺線維症に応答して動的変化を示す遺伝子の同定と検証
Detection of Pulmonary Fibrosis with a Collagen-Mimetic Peptide
IM Borgula, S Shuvaev, E Abston, NJ Rotile… - ACS Sensors, 2023
… Idiopathic pulmonary fibrosis (IPF) is a disease of unknown etiology that is characterized by excessive deposition and abnormal remodeling of collagen. IPF has a mean survival time of only 2–5 years from diagnosis, creating a need to detect …
- コラーゲン模倣ペプチドによる肺線維症の検出
[HTML] ADRB2 inhibition combined with antioxidant treatment alleviates lung fibrosis by attenuating TGFβ/SMAD signaling in lung fibroblasts
R Wan, L Wang, Y Duan, M Zhu, W Li, M Zhao, H Yuan… - Cell Death Discovery, 2023
… Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung disease that is characterized by excessive fibroblast activation and extensive accumulation of extracellular matrix, ultimately leading to the deterioration of lung …
- ADRB2 阻害と抗酸化治療を組み合わせると、肺線維芽細胞における TGFβ/SMAD シグナル伝達が減弱するため、肺線維症が軽減されます。
U-net Convolutional Neural Network applied to progressive fibrotic interstitial lung disease: is progression at CT scan associated with a clinical outcome?
X GUERRA, S RENNOTTE, C FETITA, M BOUBAYA… - Respiratory Medicine and …, 2023
… Idiopathic pulmonary fibrosis (IPF) is the most common and severe progressive fibrotic ILD [4]. Other idiopathic interstitial pneumonias (IIP), such as idiopathic … Progressive pulmonary fibrosis is defined as at least two of three criteria occurring …
- U-net 畳み込みニューラル ネットワークを進行性線維性間質性肺疾患に適用: CT スキャンでの進行は臨床転帰と関連しているか?
Edn1 is a Disease-Specific Marker in Endothelial Cells During Atherosclerosis
D Dy - Circulation, 2023
… This analysis also predicted upregulation of pulmonary fibrosis idiopathic signaling, wound healing signaling, pathogen induced cytokine storm signaling, and hepatic fibrosis signaling pathways. This EndMT process, characterized by a single …
[HTML] Role of Multidisciplinary Team Meetings in the Diagnosis and Management of Diffuse Parenchymal Lung Diseases in a Tertiary Care Hospital
MA Khan, N Sherbini, S Alyami, A Al-Harbi, S Alrajhi… - Avicenna Journal of …, 2023
… The most common consensus clinical diagnosis after an ILD-MDT discussion was chronic hypersensitivity pneumonitis/idiopathicpulmonary fibrosis in 17 patients (14%), followed by idiopathic pulmonary fibrosis and connective tissue disease associated …
- 三次医療病院におけるびまん性肺実質肺疾患の診断と管理における多職種チーム会議の役割
23/11/07
Inhalation of taraxasterol loaded mixed micelles for the treatment of idiopathic pulmonary fibrosis
T Zhang, C Sun, S Yang, Z Cai, S Zhu, W Liu, Y Luan… - Chinese Chemical Letters, 2023
… Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal lung disease characterized by … Current anti-fibrotic drugs for IPF treatment in the clinic lack selectivity and demonstrate … An IPF model was constructed through the pulmonary …
- 特発性肺線維症の治療のためのタラキサステロール含有混合ミセルの吸入
EP06. 06-07 Surveying for Lung Cancer after Idiopathic Pulmonary Fibrosis at Pham Ngoc Thach Hospital-Viet Nam in 5 year (2017-2021)
NS Lam - Journal of Thoracic Oncology, 2023
… Introduction: Idiopathic pulmonary fibrosiswill be leading to many sequelae, including lung cancer. Especially in patients with idiopathicpulmonary fibrosis who have … mination of the proportion of patients with lung cancer occurring after …
- ベトナムのファムゴックタック病院における特発性肺線維症後の肺がんに関する5年間の調査（2017～2021年）
A comprehensive cuproptosis score and associated gene signatures reveal prognostic and immunological features of idiopathic pulmonary fibrosis
C Jing, R Fu, X Liu, G Zang, X Zhu, CAN WANG… - Frontiers in Immunology
… Copper regulates the pathogenesis of Idiopathic pulmonary fibrosis (IPF), but the mechanism of action underlying cuproptosis in IPF remains … ssGSEA and the Cibersort algorithm assessed the immune profile of IPFpatients. GSEA and GSVA …
- 包括的な白銅症スコアと関連遺伝子サインにより、特発性肺線維症の予後および免疫学的特徴が明らかに
EP01. 01-20 Evaluation of Perioperative Nintedanib for Lung Cancer with Idiopathic Pulmonary Fibrosis
R Sumiya, T Banno, H Ueno, S Hirayama, K Suzuki - Journal of Thoracic Oncology, 2023
… Idiopathic pulmonary fibrosis (IPF) is a progressive diffuse lung disease, and patients with IPF sometimes develop an acute exacerbation of IPF … In this retrospective study, nintedanib, an antifibrotic agent, was perioperatively administered to IPF …
- 特発性肺線維症を伴う肺がんに対する周術期ニンテダニブの評価
MA18. 08 A Phase 2 Study of Carboplatin, Etoposide and Nintedanib for Unresectable Small-Cell Lung Cancer with Idiopathic Pulmonary Fibrosis
Y Agemi, S Ikeda, T Ogura, T Tokito, H Kenmotsu, K Ito… - Journal of Thoracic …, 2023
… idiopathic pulmonary fibrosis (IPF). The objective of this study is to assess the safety and efficacy of carboplatin, etoposide, and nintedanib combination therapy for unresectable SCLC with comorbid IPF… limited or extensive disease SCLC with IPF …
EP06. 06-10 Cancer-Associated Fibroblasts and Estrogen Receptor Beta in Lung Cancer with Idiopathic Pulmonary Fibrosis
E Nakajima - Journal of Thoracic Oncology, 2023
… Idiopathic pulmonary fibrosis (IPF) is associated with an increased risk of lung cancer, and lung cancer with IPF has poor prognosis. Transforming growth factor (TGF) β is a profibrogenic cytokine in the … We investigated the relation between CAFs …
- 特発性肺線維症を伴う肺がんにおけるがん関連線維芽細胞とエストロゲン受容体ベータ
EP06. 05-12 Histopathologic Changes of the Perioperative Pirfenidone Therapy in Lung Cancer with Idiopathic Pulmonary Fibrosis
H Oeda, Y Sakairi, M Ota, Y Sata, T Toyoda, T Inage… - Journal of Thoracic …, 2023
… Idiopathic pulmonary fibrosis (IPF) is a progressive diffuse pulmonary disease prone to lung cancer complications and can cause acute exacerbations with a high mortality rate. The antifibrotic agent, pirfenidone (PFD), has proven to slow the …
- 特発性肺線維症を伴う肺癌における周術期ピルフェニドン療法の組織病理学的変化
[HTML] Cluster features in fibrosing interstitial lung disease and associations with prognosis
Y Wang, D Sun, J Wang, S Yu, N Wu, Q Ye - BMC Pulmonary Medicine, 2023
… etiology, including idiopathic pulmonaryfibrosis (IPF), connective tissue disease-associated interstitial lung disease (CTD-ILD), idiopathic non-specific interstitial pneumonia (iNSIP), fibrotic hypersensitivity pneumonitis (FHP); unclassifiable idiopathic interstitial …
- 線維化性間質性肺疾患におけるクラスターの特徴と予後との関連
EP07. 02-07 Prospective Study of Hypofractionated Proton Therapy for Inoperable Early Stage Non-small Cell Lung Cancer
K Yang, JM Noh, W Lee, HY Park, H Yoo, SH Shin… - Journal of Thoracic …, 2023
… The two third patients had underlying lung disease; idiopathic pulmonary fibrosis (IPF) in 7 (25.9%), combined pulmonary fibrosis and emphysema in 4 (14.8%), and chronic obstructive pulmonary disease in 7 (25.9%) patients. Clinical T-stages were …
- 手術不能な早期非小細胞肺がんに対する低分割陽子線治療の前向き研究
Pulmonary Fibroelastosis-A Review
DJK Yombo, S Madala, CP Vemulapalli, HH Ediga… - Matrix Biology, 2023
… PPFE can be idiopathic or associated with prior initiating factors, including bone marrow … A study of 419 patients with idiopathic interstitial pneumonia detected radiologic PPFE in 24%[… Among a cohort of 445 patients with idiopathic …
- 肺線維弾性症 - レビュー
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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
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