AIとIPFと癒しの音楽

特発性肺線維症 idiopathic pulmonary fibrosis (IPF)患者によるIPF関連学術情報の収集とシェア。癒しの音楽もお届けしています。

2022-01-01から1年間の記事一覧

抗炎症、抗線維化、抗酸化、抗アポトーシス、抗腫瘍、および/または抗SARS-CoV-2として有望な標的とされるピルフェニドンの可能なメカニズムの調査

" Investigating the possible mechanisms of pirfenidone to be targeted as a promising anti-inflammatory, anti-fibrotic, anti-oxidant, anti-apoptotic, anti-tumor, and/or anti … SA Antar, MA Saleh, AA Al-Karmalawy - Life Sciences, 2022 … It i…

米国における特発性肺線維症以外の線維化性間質性肺疾患患者における疾患進行の請求ベースの有病率

" [HTML] Claims-based prevalence of disease progression among patients with fibrosing interstitial lung disease other than idiopathic pulmonary fibrosis in the United States D Singer, LGS Bengtson, CS Conoscenti, M Laouri… - Annals of the …

線維増殖性疾患の治療のための DNM3OS/miR-199a~214 クラスターの標的化

" [PDF] Targeting the DNM3OS/miR-199a~ 214 cluster for the treatment of fibroproliferative diseases F Brousseau, S Bellusci, M Perrais10, F Broly, P Barbry… … therapeutic target for refractory fibrotic diseases such as idiopathic pulmonary…

特発性肺線維症における細胞外小胞:病因と治療

" [HTML] Extracellular vesicles in idiopathic pulmonary fibrosis: pathogenesis and therapeutics Y Fujita - Inflammation and Regeneration, 2022 … Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease that occurs due to increased…

エアロゾル化のための微粉化薬物粒子の修飾

" Modification of Micronized Drug Particles for Aerosolization T Bajaj, VP Kaur, U Anwekar, D Chitkara, C Singh - Organ Specific Drug Delivery and …, 2022 … 10 Inhalation or pulmonary delivery could be a better strategy to treat a variety …

特発性肺線維症の中国人患者における小気道機能障害

" [HTML] Small airway dysfunction in Chinese patients with idiopathic pulmonary fibrosis X Zhang, B Xie, C Ban, Y Ren, Q Ye, M Zhu, Y Liu… - BMC Pulmonary Medicine, 2022 … Idiopathic pulmonary fibrosis (IPF), which is the most common form …

血清ヒト精巣上体タンパク質4の上昇は、特発性肺線維症における疾患の重症度および生存率の低下と関連しする:コホート研究

" [PDF] Elevated serum human epididymis protein 4 is associated with disease severity and worse survival in idiopathic pulmonary fibrosis: a cohort study M Tian, K Meng, Y Gao, J Zhang, M Xie, Y Tian, X Liu… - 2022 … Idiopathic pulmonary f…

特発性肺線維症の合併症を伴うCOVID-19患者におけるニンテダニブの有益な効果:症例報告。

" [PDF] The beneficial effect of Nintedanib in the COVID-19 patient with the complication of Idiopathic Pulmonary Fibrosis: A Case report. SM Besekar - IJCRHS| International Journal of Case Reports for …, 2022 … The greatest threat of seve…

全身性硬化症のブレオマイシン誘発マウスモデルにおける低分子量ヘパリン処理による遊走能および肝細胞増殖因子分泌の増強された脂肪由来間葉系幹/間質細胞の治療効果

" [HTML] Therapeutic effects of adipose-derived mesenchymal stem/stromal cells with enhanced migration ability and hepatocyte growth factor secretion by low … T Suzuka, T Kotani, T Saito, S Matsuda, T Sato… - Arthritis research & …, 2022 -…

間質性肺疾患に対するnintedanibニンテダニブの価値に関する多基準決定分析

" [PDF] A multi-criteria decision analysis on the value of nintedanib for interstitial lung diseases N Zozaya, MIA Basterrechea, E Bollo, I Castellví… - International Journal of …, 2022 … of nintedanib for non-idiopathic progressive fibros…

インターロイキン 31 は、全身性硬化症における線維症と T ヘルパー 2 分極を促進

" [HTML] Interleukin-31 promotes fibrosis and T helper 2 polarization in systemic sclerosis A Kuzumi, A Yoshizaki, KM Matsuda, H Kotani… - Nature …, 2021 - nature.com … increased in fibrotic lungs of BLM-SSc mice 33 . Furthermore, … fibros…

肺線維症 (PF) におけるカルシウム感知受容体 (CASR) の役割と、in vitro PF モデルにおける線維化促進性変化を逆転させる CASR 阻害剤の能力の決定

" [PDF] Determining the role of the calcium-sensing receptor (CASR) in pulmonary fibrosis (PF) and the ability of a CASR inhibitor to reverse profibrotic changes in an in vitro … KL Wolffs - 2022 … Idiopathic pulmonary fibrosis (IPF) is a …

フェロトーシス (ferroptosis)と鉄蓄積の阻害は、ブレオマイシンモデルで肺線維症を軽減する

" [HTML] Inhibition of ferroptosis and iron accumulation alleviates pulmonary fibrosis in a bleomycin model Z Pei, Y Qin, X Fu, F Yang, F Huo, X Liang, S Wang… - Redox Biology, 2022 … Idiopathic pulmonary fibrosis (IPF) is a chronic progre…

進行性線維性間質性肺疾患の日本人患者における疾患の進行と安全性に対するニンテダニブの効果:INBUILD試験全体からのさらなるサブセット分析

" [HTML] Effects of nintedanib on disease progression and safety in Japanese patients with progressive fibrosing interstitial lung diseases: Further subset analysis from the … T Ogura, T Suda, N Inase, Y Nishioka, A Azuma… - Respiratory In…

COVID-19ワクチン接種後の間質性肺疾患患者における急性増悪の発生率

" Incidence of acute exacerbation in patients with interstitial lung disease after COVID-19 vaccination M Sakayori, E Hagiwara, T Baba, H Kitamura, A Sekine… - Journal of Infection and …, 2022 … idiopathic pulmonary fibrosis (IPF) criteria…

線維症との戦い

" [HTML] Fighting fibrosis M Senior - Nature Biotechnology … Two recent sets of positive clinical data have bucked the trend in the failure-strewn idiopathic pulmonary fibrosis (IPF) field: BI’s phase 2 data for phosphodiesterase 4B (PDE4B…

特発性肺線維症治療のための病理学的コラーゲン標的化および浸透性リポソーム

" Pathological collagen targeting and penetrating liposomes for idiopathic pulmonary fibrosis therapy MY Yang, YJ Lin, MM Han, YY Bi, XY He, L Xing… - Journal of Controlled …, 2022 … Idiopathic pulmonary fibrosis (IPF) is a fibrotic inters…

臨床応用におけるポリファーマコロジー:呼吸器ポリファーマコロジー

" Polypharmacology in Clinical Applications: Respiratory Polypharmacology Z Wang, B Yang - Polypharmacology, 2022 … diseases include cystic fibrosis and idiopathic pulmonary fibrosis (IPF). IPF is characterized by a chronic progressive dec…

MAD2L1の阻害は、ミトコンドリア機能の障害と細胞老化の誘導を介して肺線維症を媒介

" [HTML] Inhibition of MAD2L1 Mediates Pulmonary Fibrosis through Impairment of Mitochondrial Function and Induction of Cell Senescence L Wang, R Wan, X Chen, X Guo, Z Li, W Zhao, P Yan… - Canadian Respiratory …, 2022 … In this study, we a…

スピロノラクトン, ミネラルコルチコイド受容体 (MR) 拮抗薬 IPF の潜在的な新しい治療法

" Elucidation of the Anti-Fibrotic Activity of a Repurposed Drug for Idiopathic Pulmonary Fibrosis J Reardon - 2022 … , has been identified as a potential novel therapy for IPF. Spironolactone is an off-patent drug for … Thus, we aimed to …

特発性肺線維症に対する優先的なホスホジエステラーゼ4B阻害剤の試験

" Trial of a Preferential Phosphodiesterase 4B Inhibitor for Idiopathic Pulmonary Fibrosis List of authors. Luca Richeldi, M.D., Ph.D., Arata Azuma, M.D., Ph.D., Vincent Cottin, M.D., Ph.D., Christian Hesslinger, Ph.D., Susanne Stowasser, …

特発性肺線維症と比較した関節リウマチ - 間質性肺疾患の血清プロテオミクスプロファイリング

" Serum proteomic profiling of rheumatoid arthritis–interstitial lung disease with a comparison to idiopathic pulmonary fibrosis X Wu, Y Jeong, SP de Frías, I Easthausen, K Hoffman… - Thorax, 2022 … Much of our knowledge regarding the path…

間質性肺疾患における在宅モニタリング

" Home monitoring in interstitial lung diseases MS Wijsenbeek, CC Moor, KA Johannson, PD Jackson… - The Lancet Respiratory …, 2022 … Disease behaviour is one of the most useful parameters for an accurate diagnosis of idiopathic pulmonary f…

HSP90阻害剤であるPimitespibは、bleomycin-ラットモデルのIL-6 / STAT3 / HIF-1α自己分泌ループのnifuroxazide誘発破壊を増強:肺線維症の管理における進化的展望

" [HTML] Pimitespib, an HSP90 inhibitor, augments nifuroxazide-induced disruption in the IL-6/STAT3/HIF-1α autocrine loop in rats with bleomycin-challenged lungs … DH El-Kashef, ME Youssef, M Nasr, M Alrouji… - Biomedicine & …, 2022 … Idio…

Fysisk aktivitet kan reducera dyspné vid KOL och 肺線維: [運動トレーニングは、COPD および IPF 患者の呼吸困難を改善可能]

" Fysisk aktivitet kan reducera dyspné vid KOL och lungfibros:[Exercise training can improve dyspnea among persons with COPD and IPF] M Emtner, M Nykvist, M Sköld, K Larsson, K Wadell - Läkartidningen, 2022 … obstructive pulmonary disease …

細胞外HSP90αは、肺線維症におけるTGF-βシグナル伝達を調節することにより細胞老化を促進する

" [PDF] Extracellular HSP90α promotes cellular senescence by modulating TGF‐β signaling in pulmonary fibrosis W Zhong, W Chen, Y Liu, J Zhang, Y Lu, X Wan, Y Qiao… - The FASEB Journal, 2022 … Aging, especially cellular senescence, is a cri…

ミエロペルオキシダーゼ抗好中球細胞質抗体陽性間質性肺疾患患者の臨床的差異

" Clinical differences among patients with myeloperoxidase–antineutrophil cytoplasmic antibody–positive interstitial lung disease K Yamaguchi, A Yamaguchi, M Ito, I Wakamatsu, M Itai… - Clinical Rheumatology, 2022 … Patients with ANCA-asso…

間質性肺炎の急性増悪に対するserum hemeoxygenase-1測定の診断的有用性の評価

" [HTML] Assessment of diagnostic utility of serum hemeoxygenase-1 measurement for acute exacerbation of interstitial pneumonias Y Kata, Y Hara, Y Tagami, A Yabe, K Murohashi… - Scientific Reports, 2022 … of idiopathic pulmonary fibrosis (…

EVs-miRNA: 慢性呼吸器疾患の新しい分子マーカー

" [PDF] EVs-miRNA: The New Molecular Markers for Chronic Respiratory Diseases P Soccio, G Moriondo, D Lacedonia, P Tondo… - Life, 2022 … The main chronic respiratory diseases are asthma, chronic obstructive pulmonary disease (COPD), sleep …

ERK / p38 MAPKシグナル伝達経路を介したマウス肺線維芽細胞のTGF-β1誘導細胞増殖、アポトーシス、活性化および分化に対する骨形成タンパク質4の影響

" [HTML] Effects of bone morphogenetic protein 4 on TGF-β1-induced cell proliferation, apoptosis, activation and differentiation in mouse lung fibroblasts via ERK/p38 MAPK … Z Cai, H Guo, J Qian, W Liu, Y Li, L Yuan, Y Zhou, R Lin… - PeerJ…