ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です！と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この１年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。
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23/12/09
Design, synthesis, and evaluation of pirfenidone-NSAIDs conjugates for the treatment of idiopathic pulmonary fibrosis
X Lu, C Zhu, Y Gao, Z Yu, Q Yan, Y Liu, M Luo, X Shi - Bioorganic Chemistry, 2023
… Idiopathic pulmonary fibrosis (IPF) is a fatal, chronic and progressive lung disease that … Idiopathic pulmonary fibrosis (IPF) is a fatal, chronic and progressive lung disease characterized by … Currently, the prevalence of Idiopathic Pulmonary …
- 特発性肺線維症治療のためのピルフェニドン-NSAIDs複合体の設計、合成、評価
Biomechanical Characteristics of Idiopathic Pulmonary Fibrosis
M SUN, F JIN, J LI, H REN, H LIU - Journal of Medical Biomechanics, 2023
… Idiopathic pulmonary fibrosis (IPF) is a common chronic … of IPF was presented, and the in vitro reproduction of biomechanical features and therapeutic strategies for targeting biomechanics wassummarized, so as to provide references for clinical …
- 特発性肺線維症の生体力学的特徴
Astragaloside IV inhibits epithelial-mesenchymal transition and pulmonary fibrosis via lncRNA-ATB/miR-200c/ZEB1 signaling pathway
Y Guan, J Zhang, X Cai, Y Cai, Z Song, Y Huang… - Gene, 2023
… Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease involving multiple … Epithelial-mesenchymal transition (EMT) is a key driver of the process of pulmonary fibrosis, … IPF were then screened from the miRNet database …
- アストラガロシド IV は、lncRNA-ATB/miR-200c/ZEB1 シグナル伝達経路を介して上皮間葉転換および肺線維症を阻害
[HTML] PTK2-associated gene signature could predict the prognosis of IPF
A Feng, YM Caro, C Gardner, G Grischo, Y Liang… - Respiratory Research, 2023
… Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease with a poor … and accuracy when evaluating clinical outcomes of IPF. Research has shown that focal adhesion kinase … Idiopathic pulmonary fibrosis is the most …
- PTK2関連遺伝子サインはIPFの予後を予測できる可能性がある
Menstrual blood-derived stem cells exosomal miR-let-7 to ameliorate pulmonary fibrosis through inhibiting ferroptosis by Sp3/HDAC2/Nrf2 signaling pathway
L Sun, X He, J Kong, H Yu, Y Wang - International Immunopharmacology, 2024
… Idiopathic pulmonary fibrosis (IPF) is the most common form of idiopathic interstitial pneumonia and one of the most common forms of … strategies for IPF in clinical are single or combinations of nidanib and pirfenidone [3]. Although they can …
- 月経血由来幹細胞エキソソーム miR-let-7 は、Sp3/HDAC2/Nrf2 シグナル伝達経路によるフェロトーシスの阻害を通じて肺線維症を改善
[HTML] Variation in information needs of patients with interstitial lung disease and their family caregivers according to long-term oxygen therapy: a descriptive study
R Sato, T Handa, K Tanizawa, T Hirai - BMC Pulmonary Medicine, 2023
… Fibrotic ILDs included idiopathic pulmonaryfibrosis (IPF), other idiopathic interstitial pneumonias (IIPs) than IPF, connective tissue disease-… Interstitial lung disease (ILD) is a group of diffuse parenchymal lung disorders, including idiopathic …
- 長期酸素療法に応じた間質性肺疾患患者とその家族の介護者の情報ニーズの変化：記述研究
Impact of recipient age on mortality among CMV-seronegative lung transplant recipients with CMV-seropositive donors
S Belga, S Hussain, RK Avery, Z Nauroz, CM Durand… - The Journal of Heart and …, 2023
… Furthermore, idiopathic pulmonary fibrosis(IPF), the leading indication for LT in North America 15 , may be associated with short telomere syndromes that confer impaired CMV immunity 16 ; indeed, shorter telomere length appears associated …
- CMV 血清反応陽性のドナーを持つ CMV 血清陰性肺移植レシピエントの死亡率に対するレシピエントの年齢の影響
miR-146a-Modified Lung Fibroblast Attenuates Transforming Growth Factor Beta-Induced Fibrosis Progress via Downregulation of Early Growth Response Factor 1
M Li, Y Liang, Y Wen, Y Chen, J Liu - Journal of Biomedical Nanotechnology, 2023
… This study investigated the role of miR-146a in lung fibrosis, specifically focusing on idiopathicpulmonary fibrosis (IPF), which is characterized by excessive alveolar fibrosis and collagen synthesis. The study aimed to explore the impact and …
- miR-146a 修飾肺線維芽細胞は、初期成長応答因子 1 の下方制御を介して、形質転換成長因子ベータ誘発性線維症の進行を軽減
Commensal Oral Microbiota, Disease Severity and Mortality in Fibrotic Lung Disease
DN O'Dwyer, JS Kim, SF Ma, P Ranjan, P Das… - American Journal of …, 2023
… and disease severity and death in idiopathicpulmonary fibrosis. Methods: We analyzed 16S rRNA gene and shotgun metagenomic sequencing data of buccal swabs from 511 patients with idiopathic pulmonary fibrosis in the multicenter …
- 共生口腔微生物叢、線維性肺疾患の重症度および死亡率
[HTML] Derazantinib Inhibits the Bioactivity of Keloid Fibroblasts via FGFR Signaling
S Xu, Y Zhu, P Wang, S Qi, B Shu - Biomedicines, 2023
… Studies have shown that fibroblast growth factor receptor-1 (FGFR1) was enhanced in pathological fibrous proliferation diseases, such as cirrhosis and idiopathic pulmonary fibrosis(IPF), suggesting the FGFR1 pathway has potential for …
- デラザンチニブは FGFR シグナル伝達を介してケロイド線維芽細胞の生物活性を阻害
23/12/07
Mechanism of Active Components of Chinese Medicine in Treatment of Idiopathic Pulmonary Fibrosis: A Review
LI Zhihui, YU Xueqing, Y Shuguang, YU Ningxia… - Chinese Journal of …, 2023
… Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with unknown etiology and poor prognosis. At present, there are few antifibrotic drugs, which have limited efficacy and cause diverse side effects in the treatment of IPF …
[PDF] LncRNA SNHG8 upregulates MUC5B to induce idiopathic pulmonary fibrosis progression by targeting miR-4701-5p
X Zhang, R Shao - Heliyon, 2023
… Long noncoding RNAs (lncRNAs) play a critical role in idiopathic pulmonary fibrosis(IPF); … an opposite role in reducing BLM-induced pulmonary fibrosis. With regard to the mechanism, … In conclusion, SNHG8 knockdown attenuated …
- LncRNA SNHG8 は miR-4701-5p を標的とすることで MUC5B を上方制御し、特発性肺線維症の進行を誘導
Effect of donor age on short-term survival of patients with idiopathic pulmonary fibrosis after lung transplantation
J WANG, C HU, H YU, X LI, B XU, D HUANG, C HU… - Organ Transplantation, 2023
… Methods Clinical data of 235 IPF donors and recipients of lung … of IPF patients after lung transplantation. Kaplan-Meier was used to draw the survival curve. Results Univariate Cox regression analysis showed that donor age was correlated …
- 肺移植後の特発性肺線維症患者の短期生存に対するドナーの年齢の影響
[PDF] Assessing the Impact of Triiodothyronine Treatment on the Lung Microbiome of Mice with Pulmonary Fibrosis
X Guo, K Xu, Q Wang, Z Han, G Yu - 2023
… Idiopathic pulmonary brosis (IPF) is an interstitial lung disease characterized by progressive pulmonary brosis (PF) exacerbation. IPF primarily affects older individuals and can lead to respiratory failure. This study aimed to assess the effects …
- 肺線維症マウスの肺マイクロバイオームに対するトリヨードチロニン治療の影響の評価
Development and characterization of inhaled nintedanib-loaded PLGA nanoparticles using scalable high-pressure homogenization technique
X Wang, D Gadhave, G Chauhan, V Gupta - Journal of Drug Delivery Science and …, 2023
… Presently, non-invasive targeted drug delivery to the lungs represents a routinely investigated approach to treat challenging disorders such as pulmonary fibrosis. Nintedanib (Nint) is an FDA-approved drug for treating idiopathicpulmonary fibrosis …
- スケーラブルな高圧均質化技術を使用した吸入ニンテダニブ担持PLGAナノ粒子の開発と特性評価
Medicated Serum of Bupleuri Radix Regulates HFL1 Apoptosis and Fibroblast-myofibroblast Transition via Smad3/Rheb Axis
LI Da, S Xiao, WU Quhui, L ZHENG, Z Silin… - Chinese Journal of …, 2023
… ObjectiveTransforming growth factor-β1 (TGF-β1) was used to stimulate human fetal lung fibroblast 1 (HFL1) for simulating the pathological process of idiopathic pulmonary fibrosis (IPF) and thereby the effects and mechanism of medicated serum …
[HTML] Optimisation of the air fraction correction for lung PET/CT: addressing resolution mismatch
F Leek, C Anderson, AP Robinson, RM Moss, JC Porter… - EJNMMI Physics, 2023
… There has been an increased interest in studying lung diseases, such as idiopathicpulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and coronavirus, with positron emission tomography/computed tomography ( PET/CT) …
- 肺 PET/CT の空気分率補正の最適化: 解像度の不一致に対処
Development of fibroblast activation protein-targeted molecular probes in non-neoplastic diseases
K XU, C LI, Y HE - Chinese Journal of Nuclear Medicine and Molecular …, 2023
… FAP is also highly expressed in some non-neoplastic diseases related to chronic inflammation and tissue remodeling, including arthritis, atherosclerosis, fibrosis of myocardial infarction, cirrhosis, and idiopathic pulmonaryfibrosis. FAPI imaging …
- 非腫瘍性疾患における線維芽細胞活性化タンパク質を標的とした分子プローブの開発
PICTORIAL REVIEW OF FIBROTIC ILD ON HRCT AND UPDATED CLASSIFICATION
AG Brixey, AS Oh, A Alsamarraie, JH Chung - CHEST, 2023
… However, the most common scenario is idiopathic UIP, in which the term idiopathicpulmonary fibrosis (IPF) is used. IPF is most common in … In a 2005 study on IPF by Lynch et al, the most prevalent CT features present on scans “consistent …
- HRCT における線維性 ILD の画像レビューと最新の分類
23/12/05
Efficacy and safety of combination therapy with pirfenidone and nintedanib in patients with idiopathic pulmonary fibrosis
JY Huh, JH Lee, JW Song - Frontiers in Pharmacology
… idiopathic pulmonary fibrosis (IPF). However, data from real-world practice are limited. Thus, we aimed to investigate the safety and efficacy of this combination therapy in patients with IPF … pirfenidone and nintedanib in 45 patients with IPF …
- 特発性肺線維症患者におけるピルフェニドンとニンテダニブの併用療法の有効性と安全性
Nintedanib-associated enterocolitis with intractable diarrhea: a case report
K Miyaguchi, Y Tsuzuki, H Uemuara, K Ishizawa… - Clinical Journal of …, 2023
… Idiopathic pulmonary fibrosis (IPF) is an intractable disease with a poor prognosis and chronic progressive course, resulting in severe fibrosis and irreversible cellulite lung formation [1]. Nintedanib is an antifibrotic agent known to bind to growth factor …
- 難治性の下痢を伴うニンテダニブ関連腸炎：症例報告
Diabetes and Obesity Effects on Lung Function-Volume II
H Zheng, W Ma, X Tang, A Lecube, LJ Yan - Frontiers in Endocrinology
… obstructive pulmonary disease (COPD) (6), idiopathic pulmonary fibrosis (IPF) (7), OVID-19 (8)… obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), and COVID-19, … effects on many lung diseases including TB, asthma, IPF …
- 糖尿病と肥満の肺機能への影響 - ボリューム II
[PDF] Toll‐interacting protein inhibits transforming growth factor beta signaling in mouse lung fibroblasts
YH Chow, C López‐Martínez, WC Liles, WA Altemeier… - FASEB BioAdvances, 2023
… Variations in the Toll-interacting protein (TOLLIP) gene have been identified in genome-wide association studies to correlate with risk of disease, mortality, and response to N-acetylcysteine therapy in idiopathic pulmonaryfibrosis. Although …
- Toll相互作用タンパク質はマウス肺線維芽細胞におけるトランスフォーミング成長因子βシグナル伝達を阻害
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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
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