ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です！と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この１年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。
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23/07/22
… of HDAC6, HDAC8, and 6/8 Inhibitors and Development of Cell-Based Drug Screening Models for the Treatment of TGF-β-Induced Idiopathic Pulmonary Fibrosis
WC Yu, TY Yeh, CH Ye, PCT Chong, YH Ho, DK So… - Journal of Medicinal …, 2023
Idiopathic pulmonary fibrosis is incurable, and its progression is difficult to control and thus can lead to pulmonary deterioration. Pan-histone deacetylase inhibitors such as SAHA have shown potential for modulating pulmonaryfibrosis yet with off-target …
- HDAC6、HDAC8、および 6/8 阻害剤の発見と、TGF-β 誘発性特発性肺線維症治療のための細胞ベースの薬物スクリーニング モデルの開発
[HTML] UBQLN1 deficiency mediates telomere shortening and IPF through interacting with RPA1
H Zhou, C Xie, Y Xie, Y He, Y Chen, C Zhang, Y Zhang… - PLoS genetics, 2023
… If these genes were deficient by mutation or loss, it would cause premature telomere shortening, which then lead to accumulate senescent cell and degenerative disorders such as idiopathic pulmonary fibrosis (IPF), cardiovascular …
- UBQLN1欠損はRPA1との相互作用を通じてテロメア短縮とIPFを媒介する
Pleuroparenchymal Fibroelastosis (PPFE)—An Update
P Evans - Current Pulmonology Reports, 2023
… Lung transplant outcomes comparable with those in idiopathic pulmonary fibrosis (IPF) have … The true incidence and prevalence of idiopathic PPFE (iPPFE) is uncertain with varying figures … Finally, an analysis of 445 cases of idiopathic …
- 胸膜実質線維弾性症 (PPFE) - 最新情報
Role of GSDM family members in airway epithelial cells of lung diseases: a systematic and comprehensive transcriptomic analysis
X Liu, L Zhang, B Zhu, Y Liu, L Li, J Hou, M Qian… - Cell Biology and Toxicology, 2023
… Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), lung adenocarcinoma … in subtypes of lung epithelia from healthy subjects and patients with COPD, IPF, SSC, LUAD, and para-tumor …
- 肺疾患の気道上皮細胞におけるGSDMファミリーメンバーの役割：系統的かつ包括的なトランスクリプトーム解析
Etiology and Pathophysiology of AVN
T Thami, A Dadra - Insights into Avascular Necrosis of the Femoral Head …, 2023
… idiopathic … , idiopathic pulmonaryfibrosis, and optic neuritis, which explains the increased incidence of AVN of the femoral head seen in patients suffering from these disorders [2]. A definitive cause remains elusive in a vast majority of cases; …
- AVNの病因と病態生理学
23/07/20
[PDF] Plasma extracellular vesicle proteins as promising noninvasive biomarkers for diagnosis of idiopathic pulmonary fibrosis
RSR Adduri, K Cai, K Velasco‐Alzate, R Vasireddy… - Journal of Extracellular …, 2023
… for diagnostic evaluation of IdiopathicPulmonary Fibrosis (IPF). However, several other interstitial lung diseases (ILDs) often exhibit radiologic pattern similar to IPF on HRCT making the diagnosis of the disease difficult. Therefore, biomarkers that …
- 特発性肺線維症の診断における有望な非侵襲性バイオマーカーとしての血漿細胞外小胞タンパク質
[PDF] Prognostic significance of peripheral blood S100A12, S100A8, S100A9 concentrations in idiopathic pulmonary fibrosis
D Ding, R Luan, Q Xue, J Yang - 2023
… idiopathic pulmonary brosis (IPF) remain unclear. In this study, the levels of S100A12, S100A8, and S100A9 in the serum of patients with IPF … This study provides further insights into the molecular mechanisms underlying IPFand …
- 特発性肺線維症における末梢血S100A12、S100A8、S100A9濃度の予後的意義
[HTML] Inhibition of tyrosine kinase Fgr prevents radiation-induced pulmonary fibrosis (RIPF)
A Mukherjee, MW Epperly, R Fisher, W Hou, D Shields… - Cell Death Discovery, 2023
… Lung fibrosis can occur for a variety of reasons such as idiopathic pulmonary fibrosis(IPF), radiation-induced pulmonary fibrosis(RIPF), exposure to toxic agents such as silica, and after COVID-19 infection [1,2,3,4]. RIPF is incurable, and current …
[HTML] Analytic Morphomics in Myositis-Related Interstitial Lung Disease
AT O'Mahony, PJ Henry, P Coghlan, M Waldron… - Lung, 2023
… In our study, we assessed a cohort of patients diagnosed with idiopathic inflammatory … Specifically, in ILD, and the IPF subtype, a decrease in muscle CSA can potentially predict … exposed to treatment as described by Wells 2013 in …
- 筋炎関連間質性肺疾患における解析的形態学
Senescence of Alveolar Epithelial Progenitor Cells: A Critical Driver of Lung Fibrosis
T Parimon, P Chen, BR Stripp, J Liang, D Jiang… - American Journal of …, 2023
… Among these, idiopathic 29 pulmonaryfibrosis (IPF), a disease of aging, is the most common and most severe form 30 of ILD and is treated largely by lung transplantation. The lack of effective treatments to 31 stop or reverse lung fibrosis …
- 肺胞上皮前駆細胞の老化：肺線維症の重大な要因
[HTML] The lung mesenchyme in development, regeneration, and fibrosis
E El Agha, VJ Thannickal - The Journal of Clinical Investigation, 2023
… , including bronchopulmonary dysplasia, idiopathic pulmonary fibrosis, and chronic obstructive … idiopathic pulmonary fibrosis(IPF) exhibited an invasive phenotype that was dependent on hyaluronan synthase 2 (HAS2) and the …
- 発生、再生、線維化における肺間葉
Lysyl Oxidase Like 2 (LOXL2) in fibrosis and cardiovascular disease
A Poe, M Martinez Yus, H Wang, L Santhanam - American Journal of Physiology-Cell …, 2023
… FF are associated with poor prognosis for 225 cancers(76) and are responsible for the fibrotic destruction and distortion of the lungs in 226 idiopathic pulmonary fibrosis (IPF)(77-80). Managing and suppressing the formation of FF has 227 the …
- 線維症および心血管疾患におけるリシルオキシダーゼ様 2 (LOXL2)
22/07/18
Insight into the relationship between forced vital capacity and transfer of the lungs for carbon monoxide in patients with idiopathic pulmonary fibrosis
T Soumagne, S Quétant, A Guillien, L Falque, D Hess… - Respiratory Medicine and …, 2023
… Forced vital capacity (FVC) is routinely used to quantify the severity and identify the progression of idiopathic pulmonary fibrosis(IPF). Although less commonly used, lung transfer of carbon monoxide (TLCO) correlates better with the severity of IPF …
- 特発性肺線維症患者における努力肺活量と一酸化炭素の肺への移動との関係についての洞察
BAG3: An enticing therapeutic target for idiopathic pulmonary fibrosis.
S Chillappagari, A Guenther, P Mahavadi - Journal of Cellular Biochemistry, 2023
… Idiopathic pulmonary fibrosis (IPF) is a dreadful and fatal disease of unknown etiology, for which no cure exists. Autophagy, a lysosomal … in IPF and discuss about how repurposing drugs that modulate this pathway may emerge as a …
- BAG3: 特発性肺線維症の魅力的な治療標的。
Pulmonary Fibrosis: Unveiling the Pathogenesis, Exploring Therapeutic Targets, and Advancements in Drug Delivery Strategies
K Aggarwal, S Arora, K Nagpal - AAPS PharmSciTech, 2023
… pulmonary fibrosis (PF), also considered idiopathic pulmonary fibrosis (IPF). Idiopathicpulmonary fibrosis, considered the most prevalent form of idiopathic … (ILD) India registry reported that the occurrence of IPF in a total number of 1084 patients …
- 肺線維症：病因の解明、治療標的の探索、薬物送達戦略の進歩
Cellular mechanisms in the pathogenesis of interstitial lung diseases
P Singh, SN Ali, S Zaheer, M Singh - Pathology-Research and Practice, 2023
… , analysing the roles of various cells in the pathogenesis of Idiopathic pulmonary fibrosis. … Pulmonary Fibrosis is no longer considered to be idiopathic because of its interaction between various causal factors which ends in a deformed repair …
- 間質性肺疾患の発症における細胞機構
[PDF] Interstitial lung disease characterization using high resolution computed tomography in tertiary care facilities
D Kalariya, S Akhani
… as idiopathic interstitial lung disease and 40 patients were diagnosed as non-idiopathicinterstitial … Idiopathic pulmonary fibrosispredicting response to therapy and survival. Am J Respir Crit … The sensitivity of highresolution CT in detecting …
- 三次医療施設における高解像度コンピューター断層撮影法を使用した間質性肺疾患の特性評価
Mitochondrial Quality Control in Lung Diseases: Current Research and Future Directions
J Liu, J Wang, A Xiong, L Zhang, Y Zhang, Y Liu… - Frontiers in Physiology
… obstructive pulmonary disease (COPD), lung cancer, and idiopathic pulmonary fibrosis(IPF). In this review, we summarize recent findings … In IPF, it appears to be involved in the disease process by participating in the cellular senescence process.Mitochondrial …
- 肺疾患におけるミトコンドリアの品質管理：現在の研究と将来の方向性
Myeloid-Derived Suppressor Cells in Inflammation and its Complications and Cancers
X Li - Frontiers in Immunology
… reported that idiopathic pulmonary fibrosis(IPF) related MDSC actually promoted IPF by activating lung fibroblasts and myofibroblast … ) to IPF lesions, which in turn activated lung fibroblasts and myofibroblast differentiation. The mechanism of B7H3-dependent …
- 炎症とその合併症および癌における骨髄由来抑制細胞
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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
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