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特発性肺線維症 idiopathic pulmonary fibrosis (IPF)患者によるIPF関連学術情報の収集とシェア。癒しの音楽もお届けしています。

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[HTML] Endothelin-1 as a Biomarker of Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Associated with Autoimmune Diseases

V Pulito-Cueto, F Genre, R López-Mejías… - International Journal of …, 2023

… , as well as its use for the differential diagnosis between idiopathic pulmonary 

fibrosis (IPF) and ILD associated with autoimmune diseases (AD-… A total of 112 

patients with IPF, 91 patients with AD-ILD (28 rheumatoid arthritis (RA), 26 systemic …

 

  • 自己免疫疾患に関連する特発性肺線維症および間質性肺疾患のバイオマーカーとしてのエンドセリン-1  



[PDF] Ambulatory oxygen therapy in lung transplantation candidates with idiopathic pulmonary fibrosis referred for pulmonary rehabilitation

A Paula, J Florian - J Bras Pneumol, 2023

… and the oxygen flow rate in idiopathic pulmonary fibrosis (IPF) patients placed on 

a lung … ) data from lung transplant candidates with IPF referred for PR and 

receiving ambulatory oxygen … PR in lung transplant candidates with IPF and …

 



Idiopathic pulmonary fibrosis: from monocyte and macrophage inflammation to a novel, non-invasive measurement of pulmonary density

F Patrucco - 2022

… Results: we included 10 IPF patients and 5 healthy volunteers. For in vitro 

experiments, we used increasing concentrations of NTD up to … in M2 

macrophages of IPF subjects after NTD stimulation. Conclusions: Our results could …

 

  • 特発性肺線維症: 単球およびマクロファージの炎症から肺密度の新しい非侵襲的測定まで 



Usual interstitial pneumonia as a stand-alone diagnostic entity: the case for a paradigm shift?

M Selman, A Pardo, AU Wells - The Lancet Respiratory Medicine, 2023

… Usual interstitial pneumonia (UIP) is characterised by a distinctive morphological 

and radiological appearance that was considered the pathognomonic hallmark of 

idiopathic pulmonary fibrosis (IPF). However, this peculiar lung remodelling pattern …

 

 

Transcriptomic and proteomic profiling of young and old mice in the bleomycin model reveals high similarity

S Klee, S Picart-Armada, K Wenger, G Birk, K Quast… - American Journal of …, 2023

… Although this model resembles key aspects of idiopathic 28 pulmonary fibrosis (IPF), 

there are limitations in its predictability for the human disease. One of the 29 main 

differences is the juvenile age of animals that are commonly used in experiments …

 

  • ブレオマイシンモデルにおける若いマウスと古いマウスのトランスクリプトームおよびプロテオミクスプロファイリングは、高い類似性を明らかに 



Indocyanine-enhanced mouse model of bleomycin-induced lung fibrosis with hallmarks of progressive emphysema

A Grandi, E Ferrini, L Mecozzi, R Ciccimarra, M Zoboli… - American Journal of …, 2023

… The development of new drugs for Idiopathic Pulmonary Fibrosis strongly relies 

on preclinical … ICG, with a significantly 38 more severe pulmonary fibrosis

accompanied by the progressiveIdiopathic Pulmonary Fibrosis (IPF) is a …

 

  • 進行性肺気腫の特徴を有するブレオマイシン誘発肺線維症のインドシアニン増強マウスモデル 



Silencing FHL2 inhibits bleomycin-induced pulmonary fibrosis through the TGF-β1/Smad signaling pathway

M Shi, H Cui, J Shi, Y Mei - Experimental Cell Research, 2023

… The mRNA expression of FHL2 in pulmonary fibrosis tissues was analyzed by 

bioinformatics. … on pulmonary fibrosis were validated in cellular and animal 

models of pulmonary fibrosis. … of pulmonary fibrosis, were detected to further …

 

  • FHL2のサイレンシングは、TGF-β1 / Smadシグナル伝達経路を介してブレオマイシン誘発肺線維症を阻害  



Using a Two-Sample Mendelian Randomization Study Based on Genome-Wide Association Studies to Assess and Demonstrate the Causal Effects of Allergic Rhinitis …

Z Zhang, G Li, L Yu, J Jiang, S Zhou, Y Jiang - International Archives of Allergy and …

… Methods: The data for AR, asthma, chronic obstructive pulmonary disease (COPD), 

bronchiectasis, idiopathic pulmonary fibrosis (IPF), and the forced expiratory volume 

in 1 s (FEV1)/forced vital capacity (FVC) ratio were obtained from genome-wide …

 

  • 慢性下部呼吸器疾患および肺機能に対するアレルギー性鼻炎の因果関係を評価および実証するためのゲノムワイド関連研究に基づく 2 サンプル メンデル無作為化研究の使用 





[PDF] A Systematic Review of the Prognostic Significance of the Body Mass Index in Idiopathic Pulmonary Fibrosis

A Zinellu, C Carru, P Pirina, AG Fois, AA Mangoni - Journal of Clinical Medicine, 2023

… with idiopathic pulmonary fibrosis (IPF). Although several patient characteristics are 

currently used to predict outcomes, the prognostic significance of the body mass index 

(BMI), a surrogate measure of excess fat mass, has not been specifically investigated …

 

  • 特発性肺線維症におけるBMIの予後的意義の系統的レビュー 



[HTML] Genetic association of circulating C-reactive protein levels with idiopathic pulmonary fibrosis: a two-sample Mendelian randomization study

K Zhang, A Li, J Zhou, C Zhang, M Chen - Respiratory Research, 2023

idiopathic pulmonary fibrosis (IPF) is often accompanied by elevated circulating C-reactive 

protein (CRP) levels. However, the causal relationship between them remains to be 

determined. Therefore, our study aimed to explore the causal effect of circulating …

 

  • 循環C反応性タンパク質レベルと特発性肺線維症との遺伝的関連:2サンプルのメンデル無作為化研究  



The impact of sleep duration on physical activity in daily life in patients with idiopathic pulmonary fibrosis

H Silva, LC Mantoani, WF Aguiar, AFL Gonçalves… - Physiotherapy Theory and …, 2023

… Despite the high prevalence of sleep disturbances in idiopathic pulmonary 

fibrosis (IPF), the relationship between physical activity in daily life (… Factors 

associated with daily physical activity in idiopathic pulmonary fibrosis patients (univariate …

 

  • 特発性肺線維症患者の日常生活における身体活動に対する睡眠時間の影響   



The Genetic Landscape of Familial Pulmonary Fibrosis

Q Liu, Y Zhou, JD Cogan, DB Mitchell, Q Sheng… - American Journal of …, 2023

… We defined FPF as the presence of idiopathic ILD in at least two bloodline 

relatives and a diagnosis of IPF in at least one of these individuals. This study was 

approved by the IRB at Vanderbilt University Medical Center (IRB#020343). Signed …

 

  • 家族性肺線維症の遺伝的景観  



[HTML] Radiological Patterns In Interstitial Lung Disease (ILD) And Changes In Six Minute Walk Test (6MWT)

M Francis, M Sajitha, VK Parameswaranpillai… - International Journal of …, 2022

Idiopathic pulmonary fibrosis with the Usual interstitial pneumonitis pattern is 

known to progress in worsening exercise capacity, spirometry and radiology. But 

ILDs with other radiological patterns like NSIP may also progress in function and …

 

  • 間質性肺疾患 (ILD) の放射線パターンと 6 分間歩行テスト (6MWT) の変化  



Silica-associated lung disease in developing countries

S Dhooria, IS Sehgal, R Agarwal - Current Opinion in Pulmonary Medicine

idiopathic pulmonary fibrosis and might be useful for progressive silicosis too [100]. 

Antifibrotic agents may be used to treat advanced silicosis on compassionate 

grounds, but must only be used in the purview of a registry or research study with …

 




Magnetic liposome as a dual-targeting delivery system for idiopathic pulmonary fibrosis treatment

X Wang, Y Wang, Z Xue, W Wan, Y Li, H Qin, Y Zhu… - Journal of Colloid and …, 2023

Idiopathic pulmonary fibrosis (IPF) is the most common form of idiopathic 

interstitial pneumonia, where M2 macrophages play an … treatment strategy for IPF

Herein, we designed a magnetic liposome based dual-targeting delivery system for …

 

  • 特発性肺線維症治療のための二重標的送達システムとしての磁性リポソーム  



[PDF] Exploring the Potential of Serum Periostin as a Predictive biomarker for Early-Onset Idiopathic Pulmonary Fibrosis: A Follow-Up Study

M Liu, ZJ Cheng, H Li, R Lin, M Xue, Y Li, J Wang… - 2023

… A total of 78 participants were involved in this study, including 51 patients with 

idiopathic pulmonary brosis (IPF) who were twice diagnosed and treated with anti- 

brotic therapy for a maximum follow-up period of 407 days according to international …

 

  • 早期発症特発性肺線維症の予測バイオマーカーとしての血清ペリオスチンの可能性を探る: フォローアップ研究  



[HTML] Idiopathic pulmonary fibrosis-novel approach on future treatment

K Pacek, M Piekarska, A Pikulicka, K Jedlina, I Szulc… - Journal of Education, Health …, 2023

Idiopathic pulmonary fibrosis (IPF) is a fatal pulmonary disease that leads to 

progressive fibrosis and extremely poor resaults.. Since the … treatment of 

idiopathic pulmonary fibrosis and point out the promising targets that could lead the …

 

  • 特発性肺線維症 - 将来の治療に対する新しいアプローチ  



Idiopathic Pulmonary Fibrosis Is Associated with Common Genetic Variants and Limited Rare Variants

AL Peljto, RZ Blumhagen, AD Walts, J Cardwell… - American Journal of …, 2023

… been reported to associate with IPF, but the extent to which rare variants genome-wide 

may contribute to the risk of IPF remains unknown. … in idiopathic pulmonary fibrosis

using an agnostic analysis strategy. These results have advanced our …

 

  • 特発性肺線維症は、一般的な遺伝子バリアントと限られたまれなバリアントに関連  



Identification of a Genetic Susceptibility Locus for Idiopathic Pulmonary Fibrosis in the 16p Subtelomere Using Whole Genome Sequencing

LJ Donoghue, AD Stockwell, M Neighbors, RX Sheng… - American Journal of …, 2023

Idiopathic pulmonary fibrosis (IPF) is a severe lung disease characterized by 

progressive interstitial fibrosis. The etiology of IPF is complex … , ancestrally-diverse 

cohorts have identified >20 common variant signals for IPF(1), and rare variant …

 

  • 全ゲノム配列決定を使用した 16p サブテロメアにおける特発性肺線維症の遺伝的感受性遺伝子座の同定  



[PDF] Aspirin alleviates pulmonary fibrosis through PI3K/AKT/mTOR-mediated autophagy pathway

J Peng, X Xiao, S Li, X Lyu, H Gong, S Tan, L Dong… - Experimental Gerontology, 2023

Idiopathic pulmonary fibrosis (IPF) is a chronic and irreversible lung disease with 

limited therapeutic options. Aspirin can alleviate liver, … of aspirin on lung fibroblast 

differentiation and pulmonary fibrosis. TGF-β1induced human embryonic lung …

 

  • アスピリンは、PI3K/AKT/mTOR を介したオートファジー経路を介して肺線維症を軽減  




[HTML] The miR-15b-Smurf2-HSP27 axis promotes pulmonary fibrosis

S Jeon, H Jin, JM Kim, Y Hur, EJ Song, YJ Lee, Y Na… - Journal of Biomedical …, 2023

Pulmonary fibrosis (PF) is a chronic and fatal interstitial lung disease involving 

deposition of … The most common type of PF is idiopathic pulmonary fibrosis (IPF), 

with a median survival of … Moreover, lung tissues of IPF patients have been shown …

 

  • miR-15b-Smurf2-HSP27軸は肺線維症を促進  





[HTML] New data showed OFEV®(nintedanib) slows decline of lung function in broad range of chronic fibrosing interstitial lung diseases with a progressive phenotype

S McClelland, R Walsh

… to be presented at the ERS Congress in Madrid, Spain, the study has met its 

primary endpoint and demonstrated the efficacy and safety of nintedanib in patients 

with a broad range of progressive fibrosing interstitial lung diseases other than …

 

  • 新しいデータは、OFEV®(ニンテダニブ)が進行性表現型を伴う広範囲の慢性線維性間質性肺疾患において肺機能の低下を遅らせることを示す



 

 

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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。

当面、毎週アラートの内容をアップしていこうと思います。

 

癒しの音楽をお届けいたします。

演奏は私のハープの師匠の邊見先生です。

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