ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です！と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この１年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。
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23/09/23
[HTML] Increased expression of OPN contributes to idiopathic pulmonary fibrosis and indicates a poor prognosis
J Ji, S Zheng, Y Liu, T Xie, X Zhu, Y Nie, Y Shen, X Han - Journal of Translational …, 2023
… Precision-cut lung slices and lentivirus-treated mice with pulmonary fibrosis were used to examine the therapeutic effect of OPN and its downstream pathways on pulmonary fibrosis. We demonstrate that the content of OPN in IPFbronchoalveolar …
- OPN の発現増加は特発性肺線維症の一因となり、予後不良を示す
H3K18 lactylation promotes the progression of arsenite-related idiopathic pulmonary fibrosis via YTHDF1/m6A/NREP
P Wang, D Xie, T Xiao, C Cheng, D Wang, J Sun, M Wu… - Journal of Hazardous …, 2023
… been proven to induce idiopathic pulmonaryfibrosis (IPF). However, the molecular mechanisms of lactylation and m6A methylation are unclear in arsenite-related IPF (As-IPF). In view of the limited understanding of molecular mechanism of m6A …
- H3K18 ラクチル化は YTHDF1/m6A/NREP を介して亜ヒ酸関連特発性肺線維症の進行を促進する
[PDF] Identification of MDK as a diagnostic biomarker for idiopathic pulmonary fibrosis and its association with immune cell infiltration
Y Bai, K Zhan, D You - 2023
… for IPF and evaluate the contribution of immune cell infiltration in IPF pathogenesis. Methods: Differentially expressed genes (DEGs) were analyzed between IPF patients and healthy controls, and functional analyses were performed. Diagnostic …
- 特発性肺線維症の診断バイオマーカーとしてのMDKの同定および免疫細胞浸潤との関連
Core fucosylation regulates alveolar epithelial cells senescence through activating of transforming growth factor-β pathway in pulmonary fibrosis.
Y Jiang, Z Wang, J Hu, W Wang, N Zhang, L Gao - Aging, 2023
… Idiopathic pulmonary fibrosis (IPF), a fatal disorder associated with aging, has a terrible prognosis. However, the potential causes of IPF… This study reveals that CF is a crucial interventional target for the treatment of pulmonary fibrosis. Blocking CF …
- コアのフコシル化は、肺線維症におけるトランスフォーミング成長因子β経路の活性化を通じて肺胞上皮細胞の老化を調節します。
23/09/21
[PDF] Alcohol septal ablation for hypertrophic obstructive cardiomyopathy and bilateral lung transplantation for idiopathic pulmonary fibrosis: a case report
V Puchnerova, J Bonaventura, R Lischke, J Veselka - European Heart Journal-Case …, 2023
… We present a unique case report of an idiopathic pulmonary fibrosis (IPF) patient with 14 hypertrophic obstructive cardiomyopathy (obstructive HCM) that demonstrates the 15 importance of pretransplant cardiology workup and …
- 肥大型閉塞性心筋症に対するアルコール中隔アブレーションと特発性肺線維症に対する両側肺移植：症例報告 繊維誘発における細胞間相互作用を考慮した代替 in vitro モデル
[PDF] An alternative in vitro model considering cell-cell interactions in fiber-induced
J Pantzke, J Pantzke, S Offer, J Pantzke, CX EJ… - Toxicology Mechanisms and …
… Until to date, there is no cure for pulmonaryfibrosis and the only treatment is to ease the … In such cases it is referred to idiopathicpulmonary fibrosis (IPF). It is estimated that the latter … evidences for a direct relationship between the …
- 肥大型閉塞性心筋症に対するアルコール中隔アブレーションと特発性肺線維症に対する両側肺移植：症例報告 繊維誘発における細胞間相互作用を考慮した代替 in vitro モデル
23/09/19
Idiopathic pulmonary fibrosis (IPF): disease pathophysiology, targets, and potential therapeutic interventions
P Saha, P Talwar - Molecular and Cellular Biochemistry, 2023
… -α) are the major modulators of IPF that mediate myofibroblast differentiation and promote fibrotic … promotes ER stress, which is predominant in IPF. This phenomenon further results in excess … In this study, we focus on the IPF and …
- 特発性肺線維症 (IPF): 疾患の病態生理学、標的、および潜在的な治療介入
[HTML] The Role of Mitochondrial Dysfunction in Idiopathic Pulmonary Fibrosis: New Perspectives for a Challenging Disease
JD Cala-Garcia, GJ Medina-Rincon, PA Sierra-Salas… - Biology, 2023
Simple Summary Idiopathic pulmonaryfibrosis (IPF) presents a significant challenge. Despite extensive research, our understanding of its underlying causes remains limited. One intriguing hypothesis proposes that disruptions in mitochondrial …
- 特発性肺線維症におけるミトコンドリア機能不全の役割：困難な疾患に対する新たな視点
Beyond epithelial damage: vascular and endothelial contributions to idiopathic pulmonary fibrosis.
J May, JA Mitchell, RG Jenkins - The Journal of Clinical Investigation, 2023
… Idiopathic pulmonary fibrosis (IPF) is a progressive scarring disease of the lung with poor survival. The incidence and mortality of IPFare rising, but … A better understanding of mechanisms underlying IPF is likely to lead to improved therapies …
- 上皮損傷を超えて: 特発性肺線維症への血管および内皮の寄与。
Disease progression in idiopathic pulmonary fibrosis under anti-fibrotic treatment.
A Cilli, F Uzer - Sarcoidosis, Vasculitis, and Diffuse Lung Diseases …, 2023
… Idiopathic pulmonary fibrosis (IPF) is the most common progressive interstitial disease of unknown etiology. The course of … of IPF, but the disease can progress even under anti-fibrotic treatment. The goal of this review is to examine and …
- 抗線維化治療下における特発性肺線維症の疾患の進行。
Regulatory effect and mechanism of LncRNA SOX2OT in idiopathic pulmonary fibrosis: Effect of LncRNA SOX2OT on lung fibers
D Li, Y He, H Chi, X Li, Q Cui, M Qiao - Cellular and Molecular Biology, 2023
… This study discusses the role played by long noncoding RNA (lncRNA) SOX2OT (SOX2OT) in idiopathic pulmonary fibrosis (IPF). By inducing … In conclusion, SOX2OT is closely related to the occurrence and development of IPF, and silencing its …
- 特発性肺線維症における LncRNA SOX2OT の調節効果とメカニズム: 肺線維に対する LncRNA SOX2OT の影響
[HTML] Multi-omics analysis reveals the mechanism of action of Ophiopogonin D against pulmonary fibrosis
S Bao, T Chen, J Chen, J Zhang, G Zhang, Y Hui, J Li… - Phytomedicine, 2023
… Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease with limited therapeutic strategies. Therefore, there is an urgent need to search for safe and effective drugs to treat this condition. Ophiopogonin D (OP-D), a steroidal …
- マルチオミクス解析により、肺線維症に対するオフィオポゴニン D の作用機序が明らかに
[HTML] TGFβ1-RCN3-TGFBR1 loop facilitates pulmonary fibrosis by orchestrating fibroblast activation
M Wu, Z Wang, X Shi, D Zan, H Chen, S Yang, F Ding… - Respiratory Research, 2023
… Idiopathic pulmonary fibrosis (IPF) bears high mortality due to unclear pathogenesis and … Idiopathic pulmonary fibrosis (IPF) is the most aggressive fibrotic intestinal lung disease (ILD) … The inevitable progression of IPF is linked to …
- TGFβ1-RCN3-TGFBR1 ループは線維芽細胞の活性化を調整することで肺線維症を促進
[PDF] Risk factors associated with COVID‐19 pneumonia in Chinese patients with pre‐existing interstitial lung disease during the SARS‐CoV‐2 pandemic
C Shao, Y Shi, R Chen, X Liu, H Huang, Y Zhao, K Xu… - Journal of Medical Virology, 2023
… IPF and non-IPF-IIP were diagnosed with the updated IIP International Multidisciplinary Classification statement. The non-IPF-IIP in our study was defined as iNSIP, cryptogenic OP, and idiopathic … male who was diagnosed with idiopathic …
Pulmonary fibrosis: from pathogenesis to clinical decision-making
T Koudstaal, M Funke-Chambour, M Kreuter… - Trends in Molecular …, 2023
… The most common form of PF is idiopathicpulmonary fibrosis (IPF), which is more prevalent in men over 60 years than in younger people. IPF is universally progressive and carries a poor prognosis with a life expectancy of 3–5 years when …
- 肺線維症: 病因から臨床上の意思決定まで
[HTML] Potential Therapeutic Targets of Resveratrol in the Prevention and Treatment of Pulmonary Fibrosis
I Ramli, T Cheriet, AM Posadino, R Giordo, H Zayed… - Frontiers in Bioscience …, 2023
… [20], which includes idiopathic pulmonaryfibrosis (IPF) [21]. PF … IPF patients develop preferentially in the peripheral adjacent zones rather than in the fibrotic areas, thereby showing different histologic distributions and immunohistochemical …
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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
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