AIとIPFと癒しの音楽

特発性肺線維症 idiopathic pulmonary fibrosis (IPF)患者によるIPF関連学術情報の収集とシェア。癒しの音楽もお届けしています。

IPF Weekly Update

ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です!と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この1年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。

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23/12/23

 

Safety and efficacy of CT-guided percutaneous microwave ablation for stage I non-small cell lung cancer in patients with comorbid idiopathic pulmonary fibrosis

JZ Peng, ZX Bie, YM Li, RQ Guo, XG Li - European Radiology, 2023

… of idiopathic pulmonary fibrosis and death in patients with idiopathic pulmonary fibrosis. … with idiopathic pulmonary fibrosis and those without idiopathic pulmonary fibrosisafter … The treatment of non-small cell lung cancer (NSCLC) patients with …

  • 特発性肺線維症を合併する患者におけるステージ I 非小細胞肺がんに対する CT ガイド下経皮マイクロ波アブレーションの安全性と有効性



Deep learning-based prognostication in idiopathic pulmonary fibrosis using chest radiographs

T Lee, SY Ahn, J Kim, JS Park, BS Kwon, SM Choi… - European Radiology, 2023

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung disease of … Thus, predicting the prognosis is important in developing management plans for patients with IPF. … diagnosis and prognostication of the patients with IPF



CA Newton, I Noth, G Raghu - European Respiratory Journal, 2023

Idiopathic pulmonary fibrosis (IPF) is a devastating condition that confers substantial morbidity and significantly reduces lifespan. Because of this, investigators have searched for modifiable risk factors to reduce the burden of IPF

  • 胃食道逆流症と特発性肺線維症:遺伝的つながりによる鶏と卵の分類  



[PDF] Gazing into the Proteomic Crystal Ball: Predicting Survival in Idiopathic Pulmonary Fibrosis

JS Lee, T Maher - American Journal of Respiratory and Critical Care …, 2023

… In many respects, idiopathic pulmonaryfibrosis (IPF) is a predictable disease. It is a condition … relatively indolent disease, with a small proportion living with IPF for 10 years or beyond[2]. Further, … Men and older individuals with IPF have worse …

  • プロテオミクスの水晶玉を見つめる: 特発性肺線維症の生存を予測 



Epigenetics of Idiopathic Pulmonary Fibrosis

SK Singh, SS Tanwar, D Patel, P Yadav, S Rajput… - Targeting Epigenetics in …, 2023

pulmonary fibrosis, available treatment and the pathways that involved in IPF progression and may develop into lung cancer. Furthermore, this highlights epigenetic and molecular mechanism of IPF … The most prevalent form of idiopathic

 

 

 

The Regulation of FASN by Exosomal miR-143-5p and miR-342-5p in Idiopathic Pulmonary Fibrosis

H Hayek, O Rehbini, B Kosmider, T Brandt, W Chatila… - American Journal of …, 2023

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive disease caused by an aberrant repair of injured … IPF and IPF patients taking pirfenidone and nintedanib and organ donors. MiRNAs expression was analyzed to study their …

  • 特発性肺線維症におけるエキソソーム miR-143-5p および miR-342-5p による FASN の制御 



Clinical course of suspected familial and sporadic idiopathic pulmonary fibrosis: Data from the PROOF-Next registry

A Froidure, B Bondue, C Dahlqvist, J Guiot, N Gusbin… - Respirology (Carlton, Vic.)

… We compared characteristics and clinical course of patients with suspected familial pulmonary fibrosis (FPF) and sporadic IPF. … Conclusion: Although younger and exposed to less tobacco, patients with FPF show an equally aggressive …

  • 家族性および散発性特発性肺線維症が疑われる場合の臨床経過:PROOF-Next レジストリからのデータ   



[PDF] Analysis of expression profile of long non-coding RNA in patients with idiopathic and COVID-19-induced pulmonary fibrosis

GF Korytina, IA Gibadullin, SR Zulkarneev… - ХИРУРГИЯ и, 2023

Idiopathic pulmonary fibrosis (IPF) comprises an interstitial lung disease with unclear pathogenesis, rapid progression, and no effective treatment. Pulmonary fibrosis … The mechanisms triggering pulmonary fibrosis and leading to its rapid …



Progressive pulmonary fibrosis: where are we now?

HK Kang, JW Song - Tuberculosis and respiratory diseases

pulmonary fibrosis (PPF) is a distinct form of progressive and fibrotic disease, occurring in ILD cases other than in idiopathic pulmonaryfibrosis (IPF). It is … Although the precise mechanisms of PPF remain unclear, there is evidence of …

  • 進行性肺線維症: 私たちは今どうなっているのでしょうか?



23/12/21

 

[PDF] Physical activity in idiopathic pulmonary fibrosis: Longitudinal change and minimal clinically important difference

K Shingai, T Matsuda, Y Kondoh, T Kimura, K Kataoka… - Chronic Respiratory …, 2023

… Reference values of physical activity to interpret longitudinal changes are not available in patients with idiopathic pulmonary fibrosis(IPF). This study aimed to define the minimal clinical important difference (MCID) of longitudinal changes in …

  • 特発性肺線維症における身体活動:長期的な変化と臨床的に重要な最小限の差異 



The mechanism of Shenlong Jianji treatment of idiopathic pulmonary fibrosis inhibits fibroblast-to-myofibroblast transformation via the TGF-β1/smads signaling …

J Pan, Y Li, X Wu, X Pan, C Liu, H Zhang, L Wang… - Journal of …, 2023

… It is widely used to treat idiopathicpulmonary fibrosis (IPF) in China. However, the underlying mechanism of SLJJ remains unclear. … Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease characterized by fibrosis. In this condition …

  • 特発性肺線維症のShenlong Jianji治療のメカニズムは、TGF-β1/smadsシグナル伝達経路を介した線維芽細胞から筋線維芽細胞への変換を阻害 



The impact of switching to a second antifibrotic in patients with idiopathic pulmonary fibrosis: a retrospective multicentre study from the EMPIRE registry

J Gregor, Y Adir, M Šterclová, N Mogulkoc, MR Kramer… - Archivos de …, 2023

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease characterised by … The introduction of antifibrotic (AF) treatment has led to significant improvements in IPF patients… Both can slow the progression of IPF but …

  • 特発性肺線維症患者における 2 番目の抗線維症への切り替えの影響: EMPIRE レジストリからの後ろ向き多施設研究 



[PDF] Causal relationship between immune cells and idiopathic pulmonary fibrosis based on Mendelian randomization analysis

CJ Carla - 2023

Idiopathic pulmonary brosis (IPF) is a progressive and irreversible … for IPF disease progression and treatment. However, studies on immune cells have limitations, and there are no concrete conclusions at present, limiting to some extent …

  • メンデルランダム化解析に基づく免疫細胞と特発性肺線維症の因果関係   



Endocrine and metabolic factors and the risk of idiopathic pulmonary fibrosis: A Mendelian randomization study

Y Jiang, R Chen, S Xu, Y Ding, M Zhang, M Bao, B He… - Frontiers in Endocrinology

… factors and idiopathic pulmonary fibrosis(IPF), yet … IPF. Methods: The instrumental variables (IVs) for 53 endocrine and metabolic factors were sourced from publicly accessible genome-wide association study (GWAS) databases, with …

  • 内分泌および代謝因子と特発性肺線維症のリスク: メンデルランダム化研究 



[PDF] Phytomedicine Plus

A Tripathi, D Tripathi, M Shukla, M Sharma

… for idiopathic pulmonary fibrosis (IPF) induction in elderly population. Stimulation of Aryl hydrocarbon receptor (AhR) under physiological stress is largely associated with Akt/mTORC1 inhibition upon aging. This in turn restores the normal autophagy …

  • フィトメディシン プラス 



S Barril, P Acebo, P Millan-Billi, A Luque, O Sibila… - Respiratory Research, 2023

… Here, we have analyzed the levels of a panel of cytokines and chemokines in BAL from PLCH patients, in order to identify a distinct immune profile to discriminate PLCH from other smoking related-ILD (SR-ILD), and comparing the results with …

  • 気管支肺胞サイトカインプロファイルにより、肺ランゲルハンス細胞組織球症患者と他の喫煙関連間質性肺疾患とが区別される 



No drug-drug interactions between selective prolyl-trna synthetase inhibitor, bersiporocin, and pirfenidone or nintedanib in healthy participants

W Shin, MY Park, J Kim, J Kim, JH Nam, J Choi… - Clinical and translational science

… Bersiporocin, a potent and selective prolyl-tRNA synthetase inhibitor, is expected to show a synergistic effect with pirfenidone or nintedanib in patients with idiopathic pulmonary fibrosis. To validate the combination therapy of bersiporocin with …

  • 健康な参加者において、選択的プロリル-trna合成酵素阻害剤であるベルシポロシンとピルフェニドンまたはニンテダニブの間に薬物間相互作用は見られない 

 

 

 

[PDF] Unagi: Deep Generative Model for Deciphering Cellular Dynamics and In-Silico Drug Discovery in Complex Diseases

J Ding, Y Zheng, J Schupp, T Adams, G Clair, A Justet… - 2023

… When applied to a dataset from 29 patients with Idiopathic Pulmonary Fibrosis (IPF), UNAGI learns disease-informed cell embeddings that 30 sharpen our understanding of disease progression, leading to the identification of potential therapeutic drug 31 …

  • Unagi: 複雑な疾患における細胞動態の解読とインシリコ創薬のための深層生成モデル 



23/12/19

 

Deciphering the role of fibrosis-specific alveolar basal cells in idiopathic pulmonary fibrosis

S Blumer - 2023

… Their precise role in IPF is incompletely understood; some studies suggest a regenerative potential in animal models, while others … towards innovative therapeutic approaches for IPF patients. While the increased presence of alveolar …

  • 特発性肺線維症における線維症特異的な肺胞基底細胞の役割の解読 



Neural Network Based Methods for the Survival Analysis of Idiopathic Pulmonary Fibrosis Patients from a Baseline CT Acquisition

AC Whitehead, AH Shahin, A Zhao, DC Alexander… - 2023 IEEE Nuclear Science …, 2023

… Neural Network Based Methods for the Survival Analysis of Idiopathic PulmonaryFibrosis Patients from a Baseline CT Acquisition Abstract: Idiopathic pulmonary fibrosis is an interstitial lung disease that causes scarring of the lungs, leading to a …



Therapeutic strategies to target connective tissue growth factor in fibrotic lung diseases

T Isshiki, S Naiel, M Vierhout, K Otsubo, P Ali… - Pharmacology & …, 2023

… The treatment of interstitial lung diseases, including idiopathic pulmonary fibrosis (IPF), remains … in IPF and other pulmonary fibrotic conditions. This review provides a comprehensive overview of the current evidence on the pathogenic role of CTGF in …

  • 線維性肺疾患における結合組織成長因子を標的とする治療戦略 



[PDF] YTHDC1 delays cellular senescence and pulmonary fibrosis by activating ATR in an m6A-independent manner

C Zhang, L Chen, C Xie, F Wang, J Wang, H Zhou… - The EMBO Journal, 2023

… Accumulation of DNA damage in the lung induces cellular senescence and promotes age-related diseases such as idiopathic pulmonary fibrosis (IPF). Hence, understanding the mechanistic regulation of DNA damage repair is important for anti-aging …

  • YTHDC1はm6A非依存的にATRを活性化することで細胞老化と肺線維症を遅らせる  



Anti-mutated citrullinated vimentin antibodies are increased in IPF patients

T Coralie, L Cédric, D Marie-Pierre, NR Pascale… - Respiratory Medicine and …, 2023

… : An increased prevalence of serum anti-MCV antibody is observed in the serum of patients with idiopathic pulmonary fibrosis (IPF) but the … Idiopathic pulmonary fibrosis (IPF) is a chronic and severe pathology characterized by progressive

  • IPF患者では抗変異シトルリン化ビメンチン抗体が増加している



[PDF] 特発性肺線維症をもつ人々の尊厳に着目したケア (ディグニティ・センタード・ケア) と基盤理論の開発

猪飼やす子 - 日本呼吸ケア・リハビリテーション学会誌, 2023

… 線維症(IPF; idiopathic pulmonary fibrosis)療養者の 生活の質は,低い傾向にあると 国内外の研究で報告されている.各国の呼吸器学会の IPF合同… 筆者は,特発性肺線維症 (idiopathicpulmonary fibrosis; IPF)の予後と生活の質に関心をもち,看護実践の開発 研究 …




[PDF] Navigating Compassion: A Comprehensive Review of Palliative Care in Respiratory Medicine

U Jadhav, J Bhanushali, A Sindhu, BSK Reddy… - Cureus, 2023

… The significance of integrating palliative care into the fabric of respiratory medicine lies in its ability to enhance the quality of life for patients facing the challenges of diseases, such as chronic obstructive pulmonary disease (COPD) …

  • 思いやりをナビゲートする: 呼吸器内科における緩和ケアの包括的なレビュー 



[PDF] Pro-Fibrotic Effects of CCL18 on Human Lung Fibroblasts Are Mediated via CCR6

K Höhne, A Wagenknecht, C Maier, P Engelhard… - 2023

… Fibrogenesis is a key pathomechanism in various pulmonary diseases, particularly idiopathic pulmonary fibrosis (IPF) [1–3] and non-specific interstitial pneumonia (NSIP); but occurs also in endstage disease lungs of patients with …

  • ヒト肺線維芽細胞に対するCCL18の線維化促進効果はCCR6を介して媒介される 



 

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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。

当面、毎週アラートの内容をアップしていこうと思います。

 

癒しの音楽をお届けいたします。 

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