AIとIPFと癒しの音楽

特発性肺線維症 idiopathic pulmonary fibrosis (IPF)患者によるIPF関連学術情報の収集とシェア。癒しの音楽もお届けしています。

IPF Weekly Update

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[PDF] Multi-Step Extracellular Matrix Remodelling and Stiffening in the Development of Idiopathic Pulmonary Fibrosis

C Júnior, A Ulldemolins, M Narciso, I Almendros… - International Journal of …, 2023

Idiopathic pulmonary fibrosis (IPF), the most common and severe form of 

pulmonary fibrosis, is a chronic and progressive disease affecting the lungs, which 

commonly results in fatal outcomes. It is characterised by irreversible loss of …

 



A combined CNN-LSTM and LSTM-QRNN model for prediction of Idiopathic Pulmonary Fibrosis Progression using CT Scans and Clinical Data

HBT Anh, TT Dinh, LT Van, H Le Minh - 2022 RIVF International Conference on …, 2022

Idiopathic Pulmonary Fibrosis (IPF), which causes scarred tissues and lung function 

damage over time, is a serious progressive lung disease. In addition, this chronic 

disease is irreversible, with unknown cures and unknown causes, so it is difficult to …

 

  • CT スキャンと臨床データを使用した特発性肺線維症の進行を予測するための CNN-LSTM と LSTM-QRNN の組み合わせモデル  



Duvelisib attenuates bleomycin-induced pulmonary fibrosis via inhibiting the PI3K/Akt/mTOR signalling pathway

X Li, X Ma, Y Miao, J Zhang, B Xi, W Li, Q Zhang… - Journal of cellular and molecular …

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial lung 

disease that … -induced pulmonary fibrosis to evaluate the effects of Duvelisib on 

pulmonary fibrosis in vivo and … of pulmonary fibrosis and provide potential drugs …

 

  • デュベリシブは、PI3K/Akt/mTORシグナル伝達経路を阻害することにより、ブレオマイシン誘発性肺線維症を軽減



[HTML] The uPA/uPAR System Orchestrates the Inflammatory Response, Vascular Homeostasis, and Immune System in Fibrosis Progression

Y Kanno - International Journal of Molecular Sciences, 2023

… Fibrotic diseases, such as systemic sclerosis (SSc), idiopathic pulmonary fibrosis

renal fibrosis and liver cirrhosis are characterized by tissue overgrowth due to 

excessive extracellular matrix (ECM) deposition. Fibrosis progression is caused by …

 

  • uPA/uPAR システムは、線維症の進行における炎症反応、血管恒常性、および免疫系を調整  



[PDF] Interleukin-11 in idiopathic pulmonary fibrosis: predictive value of prognosis and acute exacerbation

T Arai, M Hirose, T Kagawa, K Hatsuda, Y Inoue - 2023

… • In this study, we measured the serum interleukin (IL)-11 level in patients with 

idiopathic pulmonary fibrosis (IPF) and investigated its predictive … predictor of 

prognosis and AE occurrence in patients with IPF, and the IL-11 level appeared to …

 

  • 特発性肺線維症におけるインターロイキン-11:予後と急性増悪の予測値   



[PDF] Mass cytometry identifies characteristic immune cell subsets in bronchoalveolar lavage fluid from interstitial lung diseases

K Hata, T Yanagihara, K Matsubara, K Kunimura… - bioRxiv, 2023

… 4 Idiopathic pulmonary fibrosis (IPF) is the most common form of ILD and has a 

median 5 survival rate of 3–5 years (2). Connective tissue disease (CTD), defined as 

systemic 6 disorders characterized by autoimmune-mediated organ damage and …

 

  • マスサイトメトリーは、間質性肺疾患の気管支肺胞洗浄液中の特徴的な免疫細胞サブセットを特定  



Nintedanib in Asian patients with progressive fibrosing interstitial lung diseases: Results from the INBUILD trial

Y Inoue, AU Wells, JW Song, Z Xu, H Kitamura, T Suda… - Respirology (Carlton, Vic.)

… Methods: Subjects with fibrosing ILDs other than idiopathic pulmonary fibrosis 

who had shown progression of ILD at any time within the prior 24 months despite 

management deemed appropriate in clinical practice were randomized to receive …

 

  • 進行性線維化間質性肺疾患のアジア人患者におけるニンテダニブ:INBUILD試験の結果 



[HTML] Lipid nanoparticle-mediated mRNA delivery in lung fibrosis

M Massaro, S Wu, G Baudo, H Liu, S Collum, H Lee… - European Journal of …, 2023

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterized by 

excessive extracellular matrix (ECM) deposition and subsequent alveolar 

remodeling. Alveolar epithelial type 2 cells (AEC2) and fibroblasts represent …

 

  • 肺線維症における脂質ナノ粒子媒介mRNA送達  

 

[HTML] Alamandine/MrgD axis prevents TGF-β1-mediated fibroblast activation via regulation of aerobic glycolysis and mitophagy

W Wang, Y Zhang, W Huang, Y Yuan, Q Hong, Z Xie… - Journal of Translational …, 2023

… Aerobic glycolysis has a crucial role in the development of idiopathic pulmonary 

fibrosis (IPF) and … degraded by this pathway, but whether they affect LF activation 

in IPF is unknown [13, 14]. … Although it is tempting to postulate a single driver …

 

  • アラマンジン/MrgD軸は、好気性解糖とマイトファジーの調節を介してTGF-β1を介した線維芽細胞の活性化を防ぐ

 

Molecular and Clinical Aspects in The Concept of Healthy Ageing

CM Gavrilescu, R Stanescu, I Bueulei, C Vicol… - 2022 E-Health and …, 2022

… Multiple studies has shown correlations between the presence of short telomeres 

and premature onset of diseases normally occurring at advanced age, such as type 

2 diabetes mellitus, cardiovascular diseases, idiopathic pulmonary fibrosis, aplastic …

 

  • 健康な老化の概念における分子的および臨床的側面 

 

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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。

当面、毎週アラートの内容をアップしていこうと思います。

 

癒しの音楽をお届けいたします。

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