<><><>
[HTML] Potential Role of Biopeptides in the Treatment of Idiopathic Pulmonary Fibrosis
S Karande, K Sharma, A Kumar, S Charan, C Patil… - Health Sciences Review, 2023
… Idiopathic pulmonary fibrosis (IPF) is a chronic lung disorder marked with lung
tissue thickening and scarring that progresses to respiratory failure. IPF symptoms …
IPF develops in during the fifth or sixth decades of life and affects men frequently …
- 特発性肺線維症の治療におけるバイオペプチドの潜在的な役割
[HTML] Cellular and Molecular Control of Lipid Metabolism in Idiopathic Pulmonary Fibrosis: Clinical Application of the Lysophosphatidic Acid Pathway
Y Nakamura, Y Shimizu - Cells, 2023
… Idiopathic pulmonary fibrosis (IPF) is a representative disease that causes fibrosis
of the … IPF is currently difficult to cure and is known to follow a chronic progressive
course, with the … , and have been reported to intensify pulmonary fibrosis via LPA …
- 特発性肺線維症における脂質代謝の細胞および分子制御：リゾホスファチジン酸経路の臨床応用
[PDF] Causal analysis of the association between gastroesophageal reflux disease and idiopathic pulmonary fibrosis
G Chen, X Gong, S Liu, J Xie, Y Wang, W Guo, W Liao… - 2023
… various factors and IPF [17–19]. This study aimed to use GWAS to evaluate the
potential causal role of GERD in IPF, providing strong … Our ndings indicate that
GERD is signi cantly associated with an increase in IPF risk, and that GERD can …
- 胃食道逆流症と特発性肺線維症の因果関係の解析
[HTML] ILD-GAP Combined with the Charlson Comorbidity Index Score (ILD-GAPC) as a Prognostic Prediction Model in Patients with Interstitial Lung Disease
H Fujii, Y Hara, Y Saigusa, Y Tagami, K Murohashi… - Canadian Respiratory …, 2023
… proposed the GAP index as a mortality prediction model for idiopathic pulmonary
fibrosis (IPF) patients, consisting of four parameters … In addition, to predict mortality
in major chronic ILD subtypes including IPF, idiopathic NSIP (iNSIP), collagen …
- 間質性肺疾患患者の予後予測モデルとしてのチャールソン併存疾患指数スコア（ILD-GAPC）と組み合わせたILD-GAP
[HTML] Inhibition of antiapoptotic BCL-2 proteins with ABT-263 induces fibroblast apoptosis, reversing persistent pulmonary fibrosis
JC Cooley, N Javkhlan, JA Wilson, DG Foster… - JCI insight, 2023
… The PF-ILD phenotype can be seen with idiopathic pulmonary fibrosis (IPF) and
pneumonoconiosis including silicosis, connective tissue disease, hypersensitivity
pneumonitis, sarcoidosis, and nonspecific interstitial pneumonia (1). Regardless of …
Comparative molecular analysis of oral submucous fibrosis and other organ fibrosis based on weighted gene co-expression network analysis.
J Chen, B Liu, X Xie, W Li - Zhong nan da xue xue bao. Yi xue ban= Journal of …, 2022
… A total of 6 057, 10 910, 27 990, 10 480, and 4 801 DEmRNAs were identified in
OSF, kidney intestinal fibrosis (KIF), liver fibrosis (LF), idiopathic pulmonary fibrosis (IPF),
and skin … The common pathways of OSF, KIF, LF, IPF, and SF mainly focus on …
- 加重遺伝子共発現ネットワーク解析に基づく口腔粘膜下線維症と他の臓器線維症の比較分子解析。
[PDF] CYB5R3 in type II alveolar epithelial cells protects against lung fibrosis by suppressing TGF-β1 signaling
M Bueno, J Calyeca, T Khaliullin, M Miller, D Álvarez… - JCI insight, 2023
… Type II alveolar epithelial cell (AECII) redox imbalance contributes to the
pathogenesis of idiopathic pulmonary fibrosis (IPF) – a deadly disease with
restricted and limited treatment options. Here, we show that expression of membrane-bound …
- II型肺胞上皮細胞のCYB5R3は、TGF-β1シグナル伝達を抑制することにより肺線維症から保護
[PDF] The role of lung resident mesenchymal stromal cells in the pathogenesis and repair of chronic lung disease
DF Doherty, L Roets, AD Krasnodembskaya - Stem Cells, 2023
… For example, in idiopathic pulmonary fibrosis, a variety of factors can stimulate
their differentiation into myofibroblasts including tumour necrosis factor-α (TNF-(α),
transforming growth factor-β1 (TGF-β1), endoplasmic reticulum (ER) stress …
- 慢性肺疾患の病因と修復における肺常在間葉系間質細胞の役割
The Effect of Pirfenidone on Idiopathic Pulmonary Fibrosis Patients of Masih Daneshvari Hospital in Tehran, Iran
A Fakharian, Y Gholampour, A Eslaminejad, A Alinejad - Journal of Iranian Medical …, 2022
… Background: Idiopathic Pulmonary Fibrosis (IPF) is the most common form of lung
fibrosis. This chronic and lethal disease is characterized by … Methods: In this study,
40 patients with IPF participated in two groups. Pulmonary indicators such as TLC …
- イラン、テヘランのMasih Daneshvari病院の特発性肺線維症患者に対するピルフェニドンの効果
[PDF] Decreased Survival and Lung Function in Progressive Pulmonary Fibrosis
MGJP Platenburg, JJ van der Vis, JC Grutters… - Medicina, 2023
… (PPF) is a recently described term reserved for patients with fibrotic ILD other than
idiopathic pulmonary fibrosis (IPF) with fast clinical deterioration. Here, survival and
prognostic biomarkers at the time of diagnosis for PPF are investigated in a fibrotic …
- 進行性肺線維症における生存率と肺機能の低下
Angiogenesis and pulmonary fibrosis
Y Wu, J Zhang, JX Zheng - Zhonghua jie he he hu xi za zhi= Zhonghua Jiehe he …, 2023
… Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and irreversible lung
interstitial disease characterized by repeated damage and … of IPF has not been
fully elucidated, and among the many mechanisms, angiogenesis may also be one …
- 血管新生と肺線維症
[HTML] Dach1 Deficiency Drives Alveolar Epithelium Apoptosis in Pulmonary Fibrosis via Modulating C-Jun/Bim Activity
Y Lu, K Tang, S Wang, Z Tian, Y Fan, B Li, M Wang… - Translational Research, 2023
… idiopathic pulmonary fibrosis … The pathogenic mechanisms of IPF are poorly
understood (20). In this study, we first performed a bioinformatics analysis of a
human IPF dataset (GSE47460) to screen DEGs between patients with IPF and HC (Supplemental …
- Dach1欠乏は、C-Jun / Bim活性の調節を介して肺線維症の肺胞上皮アポトーシスを促進
Adipocytes, adipokines and metabolic alterations in pulmonary fibrosis
K El Husseini, N Poté, M Jaillet, P Mordant, H Mal… - Revue des Maladies …, 2023
… Idiopathic pulmonary fibrosis (IPF) is a fatal respiratory disease characterized by
severe … IPF pathophysiology. In this mini-review, we will discuss the potential
involvement of the adipocyte secretome and its paracrine or endocrine-based …
- 肺線維症における脂肪細胞、アディポカインおよび代謝変化
[PDF] Risk Stratifying Interstitial Lung Abnormalities to Guide Early Diagnosis of Interstitial Lung Diseases
D Gern - 2023
… Studies in idiopathic pulmonary fibrosis (IPF) demonstrated that antifibrotic
therapies also … ILDs which share with untreated idiopathic pulmonary fibrosis (IPF)
a natural course characterized … In two early cohorts, including patients with both …
- 間質性肺疾患の早期診断を導くための間質性肺異常のリスク層別化
[HTML] Plant miRNA osa-miR172d-5p suppressed lung fibrosis by targeting Tab1
M Kumazoe, F Ogawa, A Hikida, Y Shimada… - Scientific Reports, 2023
… Lung fibrosis, including idiopathic pulmonary fibrosis, is an intractable disease …
a potent candidate for the treatment of lung fibrosis, including idiopathic pulmonary
fibrosis. … plays an indispensable role in pulmonary fibrosis 26 , including …
- 植物miRNA osa-miR172d-5pはTab1を標的として肺線維症を抑制
[HTML] Small-molecule-mediated OGG1 inhibition attenuates pulmonary inflammation and lung fibrosis in a murine lung fibrosis model
L Tanner, AB Single, RKV Bhongir, M Heusel… - Nature Communications, 2023
… as idiopathic pulmonary fibrosis (IPF) are caused by persistent micro-injuries to
alveolar epithelial tissues accompanied by aberrant repair processes. IPF is …
Idiopathic pulmonary fibrosis (IPF) is an irreversible disorder characterized by …
- 低分子媒介OGG1阻害は、マウス肺線維症モデルにおける肺炎症と肺線維症を軽減
Pleuroparenchymal Fibroelastosis (PPFE)
B Seth, SK Danoff - Rare Lung Diseases, 2023
… In 2013, PPFE was listed as a rare idiopathic interstitial pneumonia, in the revised
multidisciplinary consensus classification of Idiopathic … Poorer prognosis of
idiopathic pleuroparenchymal fibroelastosis compared with idiopathic pulmonary …
- 胸膜実質線維弾性症（PPFE）
Hyaluronan in the Pathogenesis of Acute and Post-Acute COVID-19 Infection
HW Barnes, S Demirdjian, NL Haddock, G Kaber… - Matrix Biology, 2023
… The severity of ARDS and the duration of illness seem to be important predictors
of pulmonary fibrosis in COVID-19 [119,120]. For a subset … COVID-19 pulmonary
fibrosis appears to be distinct from idiopathic pulmonary fibrosis (IPF) and other …
- 急性および急性後のCOVID-19感染の病因におけるヒアルロン酸
[HTML] Wilms Tumor 1-Driven Fibroblast Activation and Subpleural Thickening in Idiopathic Pulmonary Fibrosis
PR Gajjala, P Singh, V Odayar, HH Ediga… - International Journal of …, 2023
… Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease that is
often fatal due to the formation of irreversible scar tissue in the distal areas of the
lung. Although the pathological and radiological features of IPF … the survival of …
- 特発性肺線維症におけるウィルムス腫瘍1駆動の線維芽細胞活性化と胸膜下肥厚
Now we know: chronic exposure to air pollutants is a risk factor for the development of idiopathic pulmonary fibrosis
L Sesé, S Harari - European Respiratory Journal, 2023
… Idiopathic pulmonary fibrosis (IPF) is the most common and most severe form of
idiopathic interstitial pneumonia, characterised by progressive deterioration of
respiratory function, few treatment options and poor outcomes [1]. Its natural history …
- 大気汚染物質への慢性的な曝露は、特発性肺線維症の発症の危険因子
[HTML] Epidemiology and comorbidities in idiopathic pulmonary fibrosis: a nationwide cohort study
JH Lee, HJ Park, S Kim, YJ Kim, HC Kim - BMC Pulmonary Medicine, 2023
Idiopathic pulmonary fibrosis (IPF) is frequently accompanied by comorbidities, with
the management of these comorbidities crucial for clinical outcomes. This study
investigated the prevalence, incidence, changes over time, and clinical impact of …
- 特発性肺線維症の疫学と合併症：全国コホート研究
[HTML] Russian Registry of Idiopathic Pulmonary Fibrosis: Clinical Features, Treatment Management, and Outcomes
S Chikina, A Cherniak, Z Merzhoeva, I Tyurin… - Life, 2023
… Idiopathic pulmonary fibrosis (IPF) is a specific variant of chronic progressive
interstitial pneumonia of unknown etiology. IPF occurs prevalently in elderly patients
and is characterized by the rapid development of progressive respiratory failure and …
- 特発性肺線維症のロシアのレジストリ: 臨床的特徴、治療管理、および結果
[HTML] Factors associated with dose reduction of pirfenidone in patients with idiopathic pulmonary fibrosis: A study based on real-world clinical data
J Kim, C Chung, HS Cho, HC Kim - Plos one, 2023
Introduction Although pirfenidone slows disease progression in patients with
idiopathic pulmonary fibrosis (IPF), in clinical practice, patients often cannot tolerate
the recommended dose because of several adverse events. This study aimed to …
- 特発性肺線維症患者におけるピルフェニドンの減量に関連する要因：実際の臨床データに基づく研究
Idiopathic Pulmonary Fibrosis Presenting with Concurrent Hypereosinophilic Syndrome: A Case Report
A Ashraf, W Lam - Journal of Allergy and Clinical Immunology, 2023
… Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterized by
worsening dyspnea, decline in forced vital capacity, and … of concurrent IHES with
IPF. There is a need for research to evaluate the role of eosinophilia in the …
- 同時性好酸球増多症候群を呈する特発性肺線維症：症例報告
Idiopathic pleuroparenchymal fibroelastosis
T Franquet, AG Palleiro - Radiología (English Edition), 2022
… pleural “cap”, a term applied to a pattern of focal pulmonary fibrosis characterised
by irregular pleural thickening of less than 5 mm located at … Compared with
idiopathic pulmonary fibrosis (IPF), the frequency of spontaneous pneumothorax is …
- 特発性胸膜実質線維弾性症
[PDF] Serum KL-6 as a Biomarker of Progression at Any Time in Fibrotic Interstitial Lung Disease
LB Jehn, U Costabel, E Boerner, J Wälscher… - Journal of Clinical Medicine, 2023
… develops over time in patients with idiopathic pulmonary fibrosis (IPF) and in 18–32%
of … a validated prediction tool for mortality risk in idiopathic pulmonary fibrosis (IPF)
[6] and other … slightly better prediction of mortality, especially in IPF and …
- 線維性間質性肺疾患における任意の時点での進行のバイオマーカーとしての血清 KL-6
New Frontiers in Therapeutics for Interstitial Lung Diseases
N Mesfin, R Sangani, DA Shankar, C Reardon - American Journal of Respiratory and …, 2023
… However, extrapolating these benefits to other lung diseases such as idiopathic
pulmonary fibrosis (IPF) remains an open question. This question becomes more
salient in light of the fact that perturbed lung microbiomes are implicated in both the …
- 間質性肺疾患治療の新境地
[PDF] WNT Through the Ranks: A Mesenchymal FOXF1-WNT5A Axis Sways Hierarchical Decisions in Alveolar Epithelial Development
E El Agha - American Journal of Respiratory Cell and Molecular …, 2023
… In this context, AEC2 hyperplasia is a feature of lung pathologies such as
idiopathic pulmonary fibrosis (IPF) and alveolar capillary dysplasia with
misalignment of pulmonary veins (ACDMPV). The latter is a rare congenital disorder …
- ランクを介したWNT：間葉FOXF1-WNT5A軸は、肺胞上皮発生における階層的決定を揺るがす
<><><>
特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
癒しの音楽をお届けいたします。
###
