IPF Weekly Update
ChatGPTなどを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です！と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。
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24/12/22
Complement factor H drives idiopathic pulmonary fibrosis by autocrine C3 regulation, suppressing macrophage phagocytosis and enhancing fibrotic progression
D Ma, Y Hua, Y Lu - Biochemical and Biophysical Research …, 2024
… Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung disease with limited therapeutic options. In this study, we … Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung disease [1]. The complexity …
- 補体因子HはオートクリンC3調節によって特発性肺線維症を促進し、マクロファージの貪食を抑制し、線維化の進行を促進する。
[HTML] Overlapping Systemic Proteins in COVID-19 and Lung Fibrosis Associated with Tissue Remodeling and Inflammation
B Svobodová, A Löfdahl, A Nybom, J Wigén… - Biomedicines, 2024
… To identify patients at risk of developing post-COVID-19 lung fibrosis, we here aimed to identify systemic proteins that overlap with fibrotic markers identified in patients with idiopathic pulmonary fibrosis (IPF) and may predict COVID-19-induced …
- COVID-19 と肺線維症における重複する全身タンパク質は組織のリモデリングと炎症に関連している
The bronchoalveolar lavage fluid CD44 as a marker for pulmonary fibrosis in diffuse parenchymal lung diseases
V Leksa, M Suchankova, E Zsemlye, J Urban, P Baráth… - Frontiers in Immunology
… Among many pathological phenotypes, pulmonary fibrosis is the most devastating and represents a characteristic sign of idiopathicpulmonary fibrosis (IPF). Despite a poor prognosis brought by pulmonary fibrosis, there are no specific diagnostic …
- びまん性実質性肺疾患における肺線維症のマーカーとしての気管支肺胞洗浄液 CD44
[PDF] Senolytics and Dietary Phytochemicals: Exploring Anti-Aging Strategies and Mechanisms in Aging and Disease
E Dias, DD Poojary
… Recent studies link chronic obstructive pulmonary disease (COPD) and idiopathicpulmonary fibrosis (IPF) to accelerated aging mechanisms, including cellular senescence. COPD's diversity, with its range of phenotypes, implies that lung aging …
- 老化防止薬と食事性植物化学物質：老化と疾患における抗老化戦略とメカニズムの探究
24/12/21
[PDF] Impact of lung-resident Mesenchymal Stem Cells on Epithelial Wound Healing in Idiopathic Pulmonary Fibrosis
A Martin-Medina, J Truyols-Vives, A Jahn, C Rio… - 2024
… (AEC) are hallmarks of the initiation and progression of idiopathic pulmonary brosis (IPF), a lethal interstitial lung disease with very … in IPF, thereby promoting disease pathogenesis. Although IPF LRMSC closely interact with alveolar epithelial …
- 特発性肺線維症における上皮創傷治癒に対する肺常在間葉系幹細胞の影響
[HTML] Diagnostic and prognostic implications of family history of fibrotic interstitial lung diseases
D Duminy-Luppi, A Alcaide-Aldeano… - Respiratory Research, 2024
… Current guidelines do not consider family aggregation or genetic information in the diagnostic algorithm for idiopathic pulmonaryfibrosis or other fibrotic ILDs. Better characterizing familial cases could help in diagnostic and treatment decision-making. …
- 線維性間質性肺疾患の家族歴の診断と予後への影響
[PDF] Circ0066187 promotes pulmonary fibrogenesis through targeting STAT3-mediated metabolism signal pathway
B Liu, W Liu, H Li, N Zhai, C Lv, X Song, S Yang - 2024
… Idiopathic pulmonary fibrosis (IPF) is a fatal and progressive interstitial lung disease of unknown cause. It is one of the most common and severe forms of idiopathic … The US Food and Drug Administration has approved only two drugs …
- Circ0066187はSTAT3を介した代謝シグナル経路を標的として肺線維形成を促進する
Pulmonary Immunocompromise in Solid Organ Transplantation
EA Lendermon, CA Hage - Clinics in Chest Medicine, 2024
… In addition, alemtuzumab induction was associated with a higher risk of epstein–barr virus (EBV)-associated posttransplant lymphoproliferative disorder in lung transplant patients with idiopathic pulmonary fibrosis(IPF) particularly in the context of primary …
- 固形臓器移植における肺の免疫不全
24/12/19
Association between the HAL score and the development of progressive pulmonary fibrosis in idiopathic interstitial pneumonia: A prospective observational study
H Nakayasu, M Karayama, N Enomoto, Y Inoue… - Respiratory Investigation, 2025
… (L), can predict acute exacerbations in patients with idiopathic interstitial pneumonia (IIP). This study aims to evaluate … idiopathicpulmonary fibrosis (IPF), the HAL score was significantly associated with PPF development (p = 0.021), while …
- 特発性間質性肺炎におけるHALスコアと進行性肺線維症の発症との関連性：前向き観察研究
Comprehensive analyses of immune activity in COVID-19-vaccinated Idiopathic Pulmonary Fibrosis patients
A Maciejewska, P Czernia, M Piotrowska-Mieczkowska… - Frontiers in Immunology
… Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease, characterized by impaired wound repair, tissue remodeling and … activity in IPF sufferers.This study investigates the immune response to the BNT162b2 COVID-19 …
- COVID-19ワクチン接種を受けた特発性肺線維症患者の免疫活動の包括的分析
The potential lipid biomarker 5-HETE for acute exacerbation identified by metabolomics in patients with idiopathic pulmonary fibrosis
Y Zhao, Y Shi, J Zhang, H Zhang, Z Wang, S Wu… - Respirology (Carlton, Vic.)
… of idiopathic pulmonary fibrosis (IPF). Emerging evidence indicates that metabolic reprogramming and dysregulation of lipid metabolism are distinctive characteristics of IPF. However, the lipid metabolic mechanisms that underlie the pathophysiology …
- 特発性肺線維症患者の急性増悪の潜在的な脂質バイオマーカー5-HETEがメタボロミクスによって特定された
[PDF] Can the haemoglobin-albumin-lymphocyte-platelet (HALP) index be used as a prognostic marker in patients diagnosed with idiopathic pulmonary fibrosis?
ES Akkurt, K Ensarioglu, BA Ozyurek, TŞ Özdemirel… - 2024
… with prognosis in patients diagnosed with IPFis unknown. In our study, we aimed to evaluate the usability of the HALP score as a prognostic marker in patients diagnosed with IPF. Material and methods Our study included 224 IPFpatients who …
- 特発性肺線維症と診断された患者の予後マーカーとして、ヘモグロビン・アルブミン・リンパ球・血小板（HALP）指数を使用できますか？
[PDF] Application of Proteomics and Metabolomics in Interstitial Lung Disease Research
B Xi, X Meng, L Zhang, W Liu, B Chen - Progress in Applied Microbiology, 2024
Interstitial lung disease (ILD) is a heterogeneous group of disorders characterized by pathological changes such as inflammatory infiltration, fibrosis, and cell proliferation involving the lung interstitium. The clinical etiology of this disease is not …
- 間質性肺疾患研究におけるプロテオミクスとメタボロミクスの応用
Coagulation and Fibrinolysis in the Diseased Lung
PMMWC Ruppert, M Korfei - perfusion
… idiopathic pulmonary fibrosis (IPF). It has been known for long that fibrin formation within the pulmonary vasculature induces ventilation-perfusion (V/Q) mismatch and propagates pulmonary vascular remodelling. Consequently, anticoagulant …
- 病変肺における凝固と線溶
Colchicine Alleviates Interstitial Lung Disease in an Experimental Autoimmune Myositis Murine Model by Inhibiting the Formation of Neutrophil Extracellular Traps
F Li, P Zhao, L Zhao, L Bai, Q Su, Y Feng, W Ma, J Zhu… - Inflammation, 2024
… The degree of interstitial pneumonia and pulmonary fibrosis were scored on the collected panoramic lung tissue pathological staining … Masson’s staining was used to assess pulmonary fibrosis. According to the area of fibrosis, pulmonary …
- コルヒチンは好中球細胞外トラップの形成を阻害することで実験的自己免疫性筋炎マウスモデルにおける間質性肺疾患を軽減する
24/12/18
What rationale for treatment of occupational interstitial lung diseases with the drugs approved for idiopathic pulmonary fibrosis?
S Bellani, P Spagnolo - Current Opinion in Allergy and Clinical Immunology
… Idiopathic pulmonary fibrosis (IPF), the prototypical progressive fibrosis ILD, is the most common and severe of the idiopathic interstitial pneumonia with a median survival of 3–5years from diagnosis without treatment [1… Proposed pathogenesis of idiopathic …
- 特発性肺線維症に承認されている薬剤で職業性間質性肺疾患を治療する根拠は何ですか?
A feasibility, wait-list design randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF)
M Crooks, C Wright, S Hart, V Allgar, A English, F Swan… - BMJ Open Respiratory …, 2024
… IntroductionBreathlessness is common and impairs the quality of life of people with idiopathic pulmonary fibrosis (IPF) and non-IPF fibrotic … breathlessness intervention in breathless IPF and non-IPF fibrotic-ILD patients.MethodsBreathless …
- 特発性肺線維症における複雑な息切れ介入の実現可能性、待機リスト設計ランダム化比較試験 (BREEZE-IPF)
Deep Learning for Predicting Acute Exacerbation and Mortality of Interstitial Lung Disease
R Teramachi, T Furukawa, Y Kondoh, M Karasuyama… - Annals of the American …, 2024
… 2018 idiopathic pulmonary fibrosis (IPF) guidelines, the 2013 idiopathic interstitial pneumonia … Predicting survival in newly diagnosed idiopathic pulmonary fibrosis: a 3-year prospective … respiratory deterioration in idiopathic pulmonary fibrosis …
- 間質性肺疾患の急性増悪と死亡率を予測するためのディープラーニング
New therapeutic approaches for fibrosis: harnessing translational regulation
SK Gill, RH Gomer - Trends in Molecular Medicine, 2024
… regulation in the context of fibrosis with an emphasis on idiopathic pulmonary fibrosis(IPF). We highlight RNA binding proteins (RBPs) as … By helping elucidate these mechanisms, this review aims to guide a novel class of therapeutics to …
- 線維症に対する新たな治療法：翻訳制御の活用
24/12/16
… in the evaluation of Sjogren's syndrome associated with interstitial lung disease, interstitial pneumonia with autoimmune features, and idiopathic pulmonary fibrosis
G Sargin, K Baris, ST Gulen - Advances in Medical Sciences, 2024
… ILDs like Sjogren’s syndrome (SjS)-ILD, interstitial pneumonia with autoimmune features (IPAF), and idiopathic pulmonary fibrosis(IPF). … -ILD, and IPF patients, and were correlated with CRP in IPAF and SjS-ILD. The cut-off value of the SII …
- 間質性肺疾患を伴うシェーグレン症候群、自己免疫性特徴を伴う間質性肺炎、特発性肺線維症の評価における全身免疫炎症指数
[HTML] Progression from nonradiographic to radiographic axial spondyloarthritis evaluated in multinational study
P Harrison
… The same is also true for patients with idiopathic pulmonary fibrosis (IPF) for whom an AE is … , which occurs during the clinical course of idiopathic pulmonary fibrosis (IPF), also occurs in … The same is also true for patients with idiopathic …
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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
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