ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です！と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この１年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。
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24/07/12
[PDF] A fibroblast-dependent TGFβ1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis
ML Cohen, AN Brumwell, TC Ho, K Garakani, G Montas… - The Journal of Clinical …, 2024
… -specific TGFβ1 signaling in ILD, the therapeutic potential of EGCG in reducing IPF-related transcriptional changes, and identify TGFβ1-noncanonical Wnt pathway crosstalk via sFRP2 as a mechanism for dysfunctional epithelial signaling in …
- 線維芽細胞依存性TGFβ1/sFRP2非典型的Wntシグナル伝達軸は特発性肺線維症における上皮化生を促進する
… Society/Associatión Latinoamericana de Tórax (ATS/ERS/JRS/ALAT) idiopathic pulmonary fibrosis and progressive pulmonary fibrosis clinical practice guideline to a …
A Tyker, J Morisset, CJ Ryerson - Canadian Journal of Respiratory, Critical Care, and …, 2024
… and management of idiopathic pulmonaryfibrosis (IPF), also defining and making treatment recommendations for progressive pulmonary fibrosis (PPF)… New recommendations in IPF include the use of transbronchial lung cryobiopsy as an …
- 2022 年版アメリカ胸部/欧州呼吸器学会/日本呼吸器学会/ラテンアメリカ胸部協会 (ATS/ERS/JRS/ALAT) 特発性肺線維症および進行性肺線維症臨床診療ガイドラインのカナダ人への適用: 意見記事
BMSCs promote alveolar epithelial cell autophagy to reduce pulmonary fibrosis by inhibiting core fucosylation modifications
J Hu, N Wang, Y Jiang, Y Li, B Qin, Z Wang, L Gao - Stem Cells, 2024
… Background: Idiopathic pulmonary fibrosisis a chronic progressive interstitial lung disease characterized by alveolar epithelial cell (AEC) … Mesenchymal stem cells derived from bone marrow (BMSCs) have the ability to regenerate damaged tissue …
- BMSCは肺胞上皮細胞のオートファジーを促進し、コアフコシル化修飾を阻害することで肺線維症を軽減する
24/07/11
Occupational and Environmental Risk Factors for Idiopathic Pulmonary Fibrosis: A Case-control Study
Y Park, HJ Kim, YW Kim, BS Kwon, YJ Lee, YJ Cho… - Respiratory Medicine, 2024
… Smoking is an important risk factor for idiopathic pulmonary fibrosis (IPF). … Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease of unknown etiology. The aim of this study was to evaluate the environmental and …
- 特発性肺線維症の職業的および環境的危険因子：症例対照研究
[HTML] Single-cell RNA sequencing reveals special basal cells and fibroblasts in idiopathic pulmonary fibrosis
C Jin, Y Chen, Y Wang, J Li, J Liang, S Zheng, L Zhang… - Scientific Reports, 2024
… Idiopathic pulmonary fibrosis (IPF) is the most predominant type of idiopathic interstitial … In order to investigate the molecular mechanisms underlying IPF further, we performed … Idiopathic pulmonary fibrosis(IPF) is the predominant form of …
- 単一細胞RNA配列解析により特発性肺線維症における特殊な基底細胞と線維芽細胞が明らかに
[PDF] Decoding Molecular Heterogeneity in Idiopathic Pulmonary Fibrosis
SM Matson - American Journal of Respiratory and Critical Care …, 2024
… of idiopathic pulmonary fibrosis (IPF) heavily rely on subjective clinical and visual radiographic or histologic features (1). Despite the grim survival associated with IPF, no … and innovative use of the technologies that can be leveraged for patients with …
- 特発性肺線維症における分子の異質性の解読
[PDF] Late to the Game: Cancer Screening Guidelines and Nodule Surveillance in Idiopathic Interstitial Pneumonias
V Santibanez, M Salvatore, M Padilla - American Journal of Respiratory and Critical …, 2024
… Idiopathic interstitial pneumonias (IIPs) constitute a diverse spectrum of inflammatory and … Brown’s meta-analysis showed that patients with idiopathic pulmonary fibrosis(IPF) had 6.4 … Two IPF cohorts demonstrated a cumulative …
N‐Phenyl‐2‐Pyridone‐Derived Endoperoxide Suppressing both Lung Cancer and Idiopathic Pulmonary Fibrosis Progression by Three‐Pronged Action
L Wang, H Wu, Z Liu, R Sun, Y Li, Y Si, Y Nie, Y Qiao… - Angewandte Chemie International …
… to the anti-IPF efficacy in vivo. Despite the specific role of triplet oxygen in anti-idiopathicpulmonary fibrosis has not been determined in this work, its potential benefits are clear based on the widespread use of supplemental oxygen therapy in IPF …
- N-フェニル-2-ピリドン由来エンドペルオキシドは3つの作用により肺癌と特発性肺線維症の進行を抑制する
The Accumulation of Senescent Cells and Diseases
G Bennett - Senotherapy: A Potential Pharmacological Strategy for …, 2024
… The diseases explored in this chapter included type 2 diabetes, idiopathic pulmonary fibrosis, obesity-induced metabolic dysfunction, viral infections, and Parkinson’s disease. An appraisal of the research examined suggests that the …
- 老化細胞の蓄積と疾患
[PDF] Bystander No More: Small Airway Involvement in IPF
K Berger, AJ Podolanczuk - American Journal of Respiratory and Critical Care …, 2024
… In the current paradigm of idiopathicpulmonary fibrosis (IPF) pathogenesis, repetitive injury to … Accordingly, the usual interstitial pneumonia (UIP) pattern that defines IPF in the … , has been recognized as one of the strongest risk factors for …
- もはや傍観者ではない：IPF における小気道の障害
Fasting alleviates bleomycin-induced lung inflammation and fibrosis via decreased Tregs and monocytes
Y Zhao, J Yang, Q Zhang, X Chen, W Liang, Y Zheng… - Advances in Medical …, 2024
… Idiopathic pulmonary fibrosis (IPF), a chronic and progressively worsening condition characterized by interstitial lung inflammation and fibrosis of unknown etiology, has a grim prognosis. The treatment options for IPF … Idiopathic pulmonary …
- 断食はTregと単球の減少によりブレオマイシン誘発性肺炎症と線維症を軽減する
Modulating in vitro lung fibroblast activation via senolysis of senescent human alveolar epithelial cells
JS Spina, TL Carr, LA Phillips, HL Knight, NE Crosbie… - Aging
… Idiopathic pulmonary fibrosis (IPF) is an age-related disease with poor prognosis and limited … that resembles aberrant epithelial cells of the IPF lung. Fibroblast activation by CM transfer is … system for profiling novel senescence-targeting …
- 老化したヒト肺胞上皮細胞のセノリシスによるin vitro肺線維芽細胞の活性化の調節
[HTML] Patient Perception of Cough in Interstitial Lung Disease; Impact of Cough Hypersensitivity
B Hirons, K Rhatigan, L Wright, H Kesavan, E Mackay… - Lung, 2024
… There are over 200 aetiologies of ILD, of which idiopathic pulmonary fibrosis (IPF) is the most common, accounting for up to 39% [4]. CC is common in ILD, particularly IPF, and affects 50–90% of patients [5,6,7,8]. The mechanism of cough in ILD is …
- 間質性肺疾患における咳嗽に対する患者の認識; 咳嗽過敏症の影響
24/07/10
[PDF] Global Burden of Lung Cancer: Prognosis, Symptom Management, And Challenges with Pulmonary Fibrosis
AM Jha, A Kumar, J Abraham, H Firdaus - International Journal of Trends in …, 2024
… Patients with idiopathic pulmonary fibrosis(IPF) face exacerbated challenges when they also develop lung cancer, impacting their … pirfenidone, in treatment of progressive pulmonary fibrosis in both idiopathicpulmonary fibrosis (IPF) and non-IPF …
- 肺がんの世界的負担：予後、症状管理、肺線維症の課題
Innovative Phytoceutical-Based Drug Delivery in the Management of Pulmonary Fibrosis: A Roadmap Towards Inhaled Therapeutics
SL Wong, JS Gan, G De Rubis, KR Paudel, S Yeung… - Journal of Drug Delivery …, 2024
… There are several type of pulmonary fibrosissuch as pneumoconiosis, drug-induced interstitial lung disease (DIILD), fibrotic hypersensitivity pneumonitis and idiopathic pulmonary fibrosis(IPF). Pneumoconiosis is a lung illness caused through inhaling …
- 肺線維症の管理における革新的な植物薬ベースの薬物送達：吸入治療へのロードマップ
Chemoreflex Sensitization Occurs in both Male and Female Rats during Recovery from Acute Lung Injury
K Kamra, IH Zucker, HD Schultz, H Wang - Frontiers in Physiology
… Introduction-Sex-specific patterns in respiratory conditions, such as asthma, COPD, cystic fibrosis, obstructive sleep apnea, and idiopathic pulmonary fibrosis, have been previously documented. Animal models of acute lung injury (ALI) have …
- 急性肺損傷からの回復中に雄と雌のラットの両方で化学反射感作が起こる
24/07/09
The importance of SII and FIB-4 scores in predicting mortality in idiopathic pulmonary fibrosis patients
GB Koyun, S Berk, OT Dogan - Clinical Biochemistry, 2024
… needed to predict mortality in patients with idiopathic pulmonary fibrosis (IPF). In this way, risky … -4) and systemic immune inflammation index (SII) are associated with mortality in IPF patients. … in the pathogenesis of IPF, we examined the FIB-4 …
- 特発性肺線維症患者の死亡率を予測する上でのSIIおよびFIB-4スコアの重要性
24/07/08
[PDF] Pirfenidone use in fibrotic diseases: What do we know so far?
A Torre, FD Martínez‐Sánchez, SM Narvaez‐Chávez… - Immunity, Inflammation and …, 2024
… 5.1 Idiopathic pulmonary fibrosis and other pulmonary fibrotic diseases treatment Idiopathicpulmonary fibrosis (IPF) is a progressive and … The latest update from the ATS/ERS/JRS/ALAT for managing idiopathicpulmonary fibrosis and progressive …
- 線維性疾患におけるピルフェニドンの使用：これまでにわかっていることは何ですか?
24/07/07
[HTML] A clinical study to monitor prescription patterns, clinical outcomes, and adverse drug reactions among patients of various interstitial lung diseases attending respiratory …
S Hasan, A Verma, S Haque, F Asif, R Nath, S Kant… - Perspectives in Clinical …, 2024
… Clubbing and rhonchi were reported maximum in idiopathic pulmonary fibrosis. It was found that psychological, breathlessness and activities, chest symptoms, and total KBILD reduced significantly after 3 months as compared to baseline with a …
Evidence from recent clinical trials in fibrotic interstitial lung diseases
V Cottin, C Valenzuela - Current Opinion in Pulmonary Medicine, 2024
… Idiopathic pulmonary fibrosis (IPF) is the prototype of fibrosing interstitial lung diseases. It is mirrored by progressive pulmonary fibrosis(PPF), an … the results of the recent clinical trials conducted in pulmonary fibrosis, especially idiopathic …
- 線維性間質性肺疾患に関する最近の臨床試験からの証拠
Proteolysis and Contractility Regulate Tissue Opening and Wound Healing by Lung Fibroblasts in 3D Microenvironments
H Xiao, K Sylla, X Gong, B Wilkowski… - Advanced Healthcare Materials
… diseases, advanced stages of idiopathicpulmonary fibrosis (IPF) and several other lung … vivo as a main profibrogenic cytokine in the progression of IPF. [ 7, 8 ] Hydrogel openings by … and newly formed collagen and are commonly observed in …
- タンパク質分解と収縮性が3D微小環境における肺線維芽細胞による組織開放と創傷治癒を制御する
Rheumatoid arthritis extra-articular lung disease: new insights on pathogenesis and experimental drugs
M Sebastiani, A Manfredi, S Croci, P Faverio… - Expert Opinion on …, 2024
… rate similar to idiopathic pulmonary fibrosis(IPF): in a CT comparison between IPF and rheumatoid lung disease, patients with IPF and patients with RA-UIP both had a 4-year survival of approximately 35% [Citation60]. A shared genetic …
- 関節リウマチの関節外肺疾患：病因と実験薬に関する新たな知見
Prognostic impact of cytokines and chemokines in bronchoalveolar lavage fluid on acute exacerbation of fibrosing interstitial lung disease
K Furuta, D Fujimoto, A Matsunashi, R Shibaki… - Respiratory Medicine, 2024
… Of the idiopathic ILD cases, 19 were diagnosed as IPF (17 and two cases in the survival and non-… idiopathic FILD cases were not categorized as either IPF or non-IPF. Moreover, there was no significant difference in the 90-day mortality rate between …
- 気管支肺胞洗浄液中のサイトカインとケモカインが線維化性間質性肺疾患の急性増悪に及ぼす予後的影響
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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
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