ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です！と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この１年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。
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24/08/09
Usefulness of serum transthyretin for prediction of the 1-year outcome in idiopathic pulmonary fibrosis: An evaluation of sarcopenic and nutritional indicators
K Fujita, A Okada, H Ohkubo, A Nakano, K Ito, Y Mori… - Respiratory Investigation, 2024
… Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic pulmonary disease with high mortality [1,2]. Although two antifibrotic drugs (pirfenidone and nintedanib) are approved for IPF treatment, they only slow down fibrosis progression [1]. IPF is …
[HTML] Induced pluripotent stem cell-derived mesenchymal stem cells reverse bleomycin-induced pulmonary fibrosis and related lung stiffness
A Chakraborty, C Wang, M Hodgson-Garms… - Biomedicine & …, 2024
… Idiopathic pulmonary fibrosis (IPF) is characterised by lung scarring and stiffening, for which … in a bleomycin (BLM)-induced model of pulmonary fibrosis. Adult male C57BL/6 mice received a … Idiopathic pulmonary fibrosis(IPF) is a chronic …
- 誘導多能性幹細胞由来間葉系幹細胞はブレオマイシン誘発性肺線維症および関連する肺硬化を改善します
[PDF] Computed Tomography Spectrum of Complications in Usual Interstitial Pneumonia Pattern in a Tertiary Care Hospital: A Descriptive Cross-sectional Study
U Debi, S Devkota, SR Choudhary, S Sagar, T Karki…
… Introduction: Idiopathic pulmonary fibrosisis the most prevalent form of interstitial lung disease, which presents as usual interstitial … Many complications are associated with idiopathic pulmonary fibrosis, which further increases the morbidity …
[HTML] Recognition and Management of Occupational Lung Diseases Associated With Environmental Changes
C Lemiere, DI Bernstein - The Journal of Allergy and Clinical Immunology: In …, 2024
… review the different respiratory diseases such as chronic bronchitis, chronic obstructive pulmonary disease, asthma, asthma-like syndrome, byssinosis, hypersensitivity pneumonitis, and idiopathic pulmonaryfibrosis linked to organic …
- 環境変化に伴う職業性肺疾患の認識と管理
24/08/08
Nintedanib and miR-29b Co-Loaded Lipoplexes in Idiopathic Pulmonary Fibrosis: formulation, characterization, and in vitro evaluation
C Duraloglu, I Baysal, S Yabanoglu-Ciftci, B Arica - Drug Development and Industrial …, 2024
Objective The present study was aimed to develop a cationic lipoplex formulation loaded with Nintedanib and miR-29b (LP-NIN-miR) as an alternative approach in the combination therapy of Idiopathic Pulmonary Fibrosis (IPF) by proving its …
- 特発性肺線維症におけるニンテダニブと miR-29b 共負荷リポプレックス: 処方、特性評価、および in vitro 評価
[PDF] CIResDiff: A Clinically-Informed Residual Diffusion Model for Predicting Idiopathic Pulmonary Fibrosis Progression
C Jiang, X Xing, Z Ou, M Liu, W Simon, G Yang… - arXiv preprint arXiv …, 2024
The progression of Idiopathic PulmonaryFibrosis (IPF) significantly correlates with higher patient mortality rates. Early detection of IPF … To this end, in this paper, we develop a novel diffusion model to accurately predict the progression of IPF by …
- CIResDiff: 特発性肺線維症の進行を予測するための臨床情報に基づく残留拡散モデル
Effect of Peitu Yifei Granules on autophagy mechanism in rats with idiopathic pulmonary fibrosis based on PI3K/Akt/mTOR signaling pathway
ZK Fan, XY Niu, YY Niu, LJ Wang, X Wang, YQ Wu… - Zhongguo Zhong yao za zhi …, 2024
… idiopathic pulmonary fibrosis(IPF) in rats, fifty specific-pathogen-free(SPF) grade male Wistar rats were randomly divided into blank group and modeling group. IPF … the phosphoinositide 3-kinase(PI3K)/Akt/mTOR signaling pathway and delay the …
- PI3K/Akt/mTORシグナル伝達経路に基づく特発性肺線維症ラットのオートファジー機構に対するPeitu Yifei Granulesの効果
Interactions between fibroblasts and monocyte-derived cells in chronic lung injuries induced by real-ambient particulate matter exposure
Y Zeng, R Zhang, Y Jiang, D Li, L Chen, G Dong… - Mutation Research-Genetic …, 2024
… 2D, we pinpointed PM exposure-induced disruptions in pro-fibrotic pathways (eg, pulmonary fibrosis idiopathic signaling pathway, inhibition of matrix metalloproteases) and inflammatory pathways (eg, pathogen-induced cytokine storm signaling pathway …
- 実際の大気中の粒子状物質への曝露によって誘発される慢性肺障害における線維芽細胞と単球由来細胞の相互作用
IL6 Receptor Inhibitors: Exploring the Therapeutic Potential Across Multiple Diseases through Drug Target Mendelian Randomization
C Fu, L Wang, W Cai - Frontiers in Immunology
… IL-6 inhibitors significantly reduced the risk of idiopathic pulmonary fibrosis (OR= 0.278, 95% [CI], 0.138-0.558; P <0.001), Parkinson's disease (OR … IL-6Ri may represent a promising therapeutic avenue for idiopathicpulmonary fibrosis …
- IL6 受容体阻害剤: 薬物標的メンデルランダム化による複数の疾患に対する治療可能性の探究
[HTML] SCIENTIFIC COLLECTIVE and ARTIFICIAL INTELLIGENCE
EC Scientists, P Khedoe
Irreversible pulmonary damage, including remodeling, fibrosis and emphysema are characteristic features of respiratory diseases, including systemic sclerosis-associated interstitial lung disease (SSc-ILD)(1), idiopathicpulmonary fibrosis (IPF) and chronic …
- 科学的集合と人工知能
24/08/05
[HTML] Therapeutic effects of MEL-dKLA by targeting M2 macrophages in pulmonary fibrosis
I Choi, IH Han, N Cha, HY Kim, H Bae - Biomedicine & Pharmacotherapy, 2024
… Idiopathic pulmonary fibrosis is a progressive lung disease characterized by excessive extracellular matrix accumulation and myofibroblast proliferation with limited treatment options available. M2 macrophages are pivotal in pulmonary …
- 肺線維症におけるM2マクロファージを標的としたMEL-dKLAの治療効果
Krebs von den Lungen-6 as biomarker of the new progressive fibrotic phenotype of interstitial lung disease
M d'Alessandro, E Conticini, L Bergantini, MA Mazzei… - Tissue and Cell, 2024
… Among idiopathic interstitial lung disease (ILD), the most common is idiopathicpulmonary fibrosis (IPF), characterized by a progressive clinical course, sometimes interrupted by high mortality events, defined as “acute exacerbation” (Agustí et al …
- 間質性肺疾患の新たな進行性線維性表現型のバイオマーカーとしてのクレブス・フォン・デン・ルンゲン-6
The role of IL-6 in pulmonary emphysema with recurrent primary spontaneous pneumothorax in a young woman: A case report
P Pratiwy, D Maranatha - Journal of Medicinal and Pharmaceutical Chemistry …, 2024
… The erratic secretion of IL-6 has been associated with the development of various respiratory conditions, encompassing asthma, COPD, and idiopathic pulmonary fibrosis(IPF). Various mediators have been shown to increase in the lungs of patient …
[HTML] The potential role of lung microbiota and lauroylcarnitine in T-cell activation associated with checkpoint inhibitor pneumonitis
W Yu, K Wang, Y He, Y Shang, X Hu, X Deng, L Zhao… - eBioMedicine, 2024
… We recruited thirteen hospitalized CIP patients, eleven idiopathic pulmonary fibrosis(IPF) patients, and ten new-onset non-small cell lung cancer patients. Bronchoalveolar lavage fluid samples were collected for 16S rRNA gene sequencing …
[HTML] Sustained amphiregulin expression in intermediate alveolar stem cells drives progressive fibrosis
R Zhao, Z Wang, G Wang, J Geng, H Wu, X Liu, E Bin… - Cell Stem Cell, 2024
… Idiopathic pulmonary fibrosis (IPF) represents one of the most common types of pulmonary fibrosis, in which fibrotic lesions and tissue thickening begin in the lung periphery and gradually progress toward the center, eventually affecting the entire …
- 中間肺胞幹細胞における持続的なアンフィレグリンの発現が進行性線維症を引き起こす
24/08/04
[HTML] Exploring the causal effect between lipid-modifying drugs and idiopathic pulmonary fibrosis: a drug-target Mendelian randomization study
G Cai, J Liu, M Cai, L Shao - Lipids in Health and Disease, 2024
… Idiopathic pulmonary fibrosis (IPF) is a … risk of IPF, the evidence is inconsistent. The present Mendelian randomization (MR) study aims to determine the association between circulating lipid traits and IPF and to assess the potential influence of lipid-modifying …
- 脂質修飾薬と特発性肺線維症の因果関係の調査：薬物標的メンデルランダム化研究
[HTML] Antifibrotics and mortality in idiopathic pulmonary fibrosis: external validity and avoidance of immortal time bias
H Hozumi, K Miyashita, E Nakatani, Y Inoue, H Yasui… - Respiratory Research, 2024
… trials reported that antifibrotics improved survival in patients with idiopathic pulmonaryfibrosis (IPF), but the results were only based on short-… Therefore, whether antifibrotics truly improve long-term survival in patients with IPF in the real …
- 特発性肺線維症における抗線維化薬と死亡率：外部妥当性と不死時間バイアスの回避
[HTML] Oxygen saturation recovery after 6-minute walk test in patients with idiopathic pulmonary fibrosis
MS Oğuz, Z Bingöl, A Pıhtılı, P Karaca Özer… - BMC Pulmonary Medicine, 2024
… The six-minute walk test (6MWT) is widely used to assess functional capacity and prognosis in patients with idiopathic pulmonary fibrosis(IPF). However, studies on oxygen saturation recovery after the 6MWT in patients with IPF are rare. In our study …
- 特発性肺線維症患者における6分間歩行テスト後の酸素飽和度の回復
[PDF] CHARACTERISTICS OF INTERSTITIAL LUNG DISEASES AND FACTORS DETERMINING PROGRESSION-FOCUS ON LUNG DISEASES WITH AUTOIMMUNE …
A Nagy - 2024
… BAL fluid lymphocytosis (>15%) might indicate NSIP, sarcoidosis, HP, drug-induced pneumonitis or CTD-ILD, while neurophil pattern might suggest idiopathic pulmonary fibrosis (IPF) (>3%), or possibly CTD-ILD. Usually macrophage …
- 間質性肺疾患の特徴と進行を規定する因子 - 自己免疫性肺疾患に焦点を当てる
A systematic review and meta-analysis of the clinical benefits and adverse reactions of anti-fibrotics in non-IPF progressive fibrosing ILD
WH Chong, D Agrawal, ZY Tan, S Venkateswaran… - Heart & Lung, 2024
… in idiopathic pulmonary fibrosis (IPF). However, its effectiveness in non-IPFprogressive fibrosing interstitial lung disease (non-IPF PF-ILD) … Idiopathic pulmonaryfibrosis (IPF) is a subtype of chronic progressive fibrosing interstitial lung …
- 非IPF進行性線維化性ILDにおける抗線維化薬の臨床的利点と副作用に関する系統的レビューとメタアナリシス
Lung Microbiota: Implications and Interactions in Chronic Pulmonary Diseases
J Zhou, W Hou, H Zhong, D Liu - Frontiers in Cellular and Infection Microbiology
… Evidence has demonstrated that changes in lung microbiota contribute to the development of major chronic lung diseases, including chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), asthma, and lung …
- 肺微生物叢：慢性肺疾患における影響と相互作用
Lactylation signature identifies liver fibrosis phenotypes and traces fibrotic progression to hepatocellular carcinoma
LN Li, WW Li, L Xiao, WN Lai - Frontiers in Immunology
… The regulatory networks of the core genes shared several transcription factors, and certain core DEGs also presented dysregulation in other liver fibrosis and idiopathic pulmonary fibrosis(IPF) cohorts, indicating that lactylation may exert …
[HTML] Predictors for acute exacerbation of interstitial pneumonia following lung cancer surgery: a multicenter study
L Yin, R Xu, X Liu, L Fu, G Qiang - BMC Pulmonary Medicine, 2024
… 91.7% (44/48) of the patients were diagnosed with idiopathic ILD of unknown etiology, including 35 cases of IPF, 8 cases of NSIP, and 1 case of desquamative interstitial pneumonia. One case of patient was diagnosed with hypersensitivity …
- 肺癌手術後の間質性肺炎の急性増悪の予測因子：多施設共同研究
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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
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