AIとIPFと癒しの音楽

特発性肺線維症 idiopathic pulmonary fibrosis (IPF)患者によるIPF関連学術情報の収集とシェア。癒しの音楽もお届けしています。

IPF Weekly Update

ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です!と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この1年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。

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24/03/09

 

[PDF] Impact of surgical lung biopsy on lung function and survival in patients with idiopathic pulmonary fibrosis in a multi‐centre registry cohort

V Marcoux, SD Lok, P Mondal, D Assayag, JH Fisher… - Respirology, 2024

… Background and Objective: Establishing an accurate and timely diagnosis of idiopathicpulmonary fibrosis (IPF) is essential for appropriate … accelerated lung function decline in patients with IPF using the Canadian Registry for Pulmonary

  • 多施設登録コホートにおける特発性肺線維症患者の肺機能と生存に対する外科的肺生検の影響



Cognitive Function in Patients With Mild Idiopathic Pulmonary Fibrosis: A Case-Control Pilot Study

H Annaka, T Nomura, H Moriyama - Occupational Therapy In Health Care, 2024

IPF showed decreased cognitive function compared to controls in verbal memory, cognitive flexibility and information processing speed. … in mild IPF, this study suggests that cognitive function declines early in the disease process of IPF. Thus …

  • 軽度の特発性肺線維症患者の認知機能: 症例対照パイロット研究



[PDF] Improvement of idiopathic pulmonary fibrosis through a combination of Astragalus radix and Angelica sinensis radix via mammalian target of rapamycin signaling …

C Sun, H Liu, J Han, B Chi, Y Koga, K Afshar, X Liu - Journal of Thoracic Disease, 2024

… for idiopathic pulmonary fibrosis (IPF) in clinic. Astragalus radix (AR; Huangqi) and Angelica sinensis radix (AS; Danggui) have been frequently used in the treatment of IPFIdiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung …

  • ラットにおけるラパマイシンシグナル伝達経路誘導オートファジーの哺乳類標的を介したレンゲとアンジェリカシネンシスの組み合わせによる特発性肺線維症の改善




Computational and in vitro screening validates the repositioning potential of Coxibs as anti-fibrotic agents

S Karande, B Das, SS Acharya, A Kumar, H Patel… - Journal of Biomolecular …, 2024

Idiopathic pulmonary fibrosis (IPF) is a life-threatening disease with a survival rate of <5 years. The TGF-β plays a significant role in the … have a role in the treatment of IPF. The main objective of the study was to identify promising drug candidates …

  • コンピュータおよびインビトロスクリーニングにより、抗線維化剤としてのコキシブの再配置の可能性が検証される



How Does Rheumatoid Arthritis Increase the Risk of Lung Cancer?

BG Kim, S Yoon, SY Lee, JW Sohn, DW Park - Journal of Thoracic Oncology, 2024

… In addition, ILD, especially idiopathicpulmonary fibrosis, shares several pathogenetic features with lung cancer, and studies have reported … The usual interstitial pneumonia type of RA-ILD, which is very similar to idiopathic pulmonary

  • 関節リウマチは肺がんのリスクをどのように高めるのでしょうか?



Supramolecular Peptide‐based Nanomaterials for the Treatment of Fibrosis

J Liu, Q Zou - Peptide Self‐Assembly and Engineering …, 2024

… Fibrogenesis can occur in a number of chronic inflammatory diseases as a general pathogenic process, such as nonalcoholic steatohepatitis, chronic kidney disease, myocardial infarction, heart failure, and idiopathic pulmonaryfibrosis



[HTML] Pulmonary Effects of Traumatic Brain Injury in Mice: A Gene Set Enrichment Analysis

WH Chan, SM Huang, YL Chiu - International Journal of Molecular Sciences, 2024

… Conditions typified by fibrosis, such as cystic fibrosis and idiopathic pulmonary fibrosis, emerged with … Our results suggest that pulmonary fibrosis could also be considered for targeted screening for … FOSL2 has also been implicated in …

  • マウスにおける外傷性脳損傷の肺への影響: 遺伝子セット濃縮解析



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24/03/05



[PDF] Astragaloside IV inhibits idiopathic pulmonary fibrosis through activation of autophagy by miR-21-mediated PTEN/PI3K/AKT/mTOR pathway

T Li, X Gao, R Jia, Y Sun, Y Ding, F Wang, Y Wang - Cellular and Molecular Biology, 2024

… In this experiment, we studied how AS-IV reduces idiopathic pulmonary fibrosis (IPF). Bleomycin (BLM) or TGF‐β1 was treated in mice or alveolar epithelial cells to mimic IPF in vivo as well as in vitro. ASV-IV alleviated levels of inflammatory cytokines and …

  • アストラガロシド IV は、miR-21 媒介 PTEN/PI3K/AKT/mTOR 経路によるオートファジーの活性化を通じて特発性肺線維症を阻害




Tetrandrine alleviates pulmonary fibrosis by inhibiting alveolar epithelial cell senescence through PINK1/Parkin-mediated mitophagy

L Chu, J Zhuo, H Huang, W Chen, W Zhong, J Zhang… - European Journal of …, 2024

Idiopathic pulmonary fibrosis (IPF) is a fatal and insidious interstitial lung disease. So far, there are no effective drugs for preventing the disease process. Cellular senescence plays a critical role in the development of IPF, with … Idiopathic

  • テトランドリンは、PINK1/パーキン媒介マイトファジーを介して肺胞上皮細胞の老化を阻害することにより、肺線維症を軽減



[HTML] Neighborhood Disparities in Interstitial Lung Disease: How Do We Capture the Most Vulnerable?

GC Goobie - Annals of the American Thoracic Society, 2024

… (ADI) score for all patients with idiopathicpulmonary fibrosis (IPF) included in the University of California, … patients with IPF who are likely missing from this cohort. (B) The natural history of … Delayed access and survival in idiopathic pulmonary fibrosis

  • 間質性肺疾患における近隣格差: 最も脆弱な人々をどのように捕捉するか?



THE ROLE OF miRNA IN PRE-CAPILLARY PULMONARY HYPERTENSION: A COMPARISON BETWEEN GROUP 1 AND GROUP 3 PH

E Salvaterra - 2024

… 27 patients diagnosed with idiopathicpulmonary arterial hypertension (IPAH), idiopathic pulmonary fibrosis, or chronic obstructive … were found in comparison to group 3 pulmonary hypertension associated with IPFand COPD. Statically …

  • 前毛細管状肺高血圧症における miRNA の役割: グループ 1 とグループ 3 PH の比較



Machine Learning of Plasma Proteomics Classifies Diagnosis of Interstitial Lung Disease

Y Huang, SF Ma, JM Oldham, A Adegunsoye, D Zhu… - American Journal of …, 2024

… Among these many syndromes, connective tissue disease (CTD-ILD) involves autoimmune mechanisms and must meet American College of Rheumatology (ACR) criteria (2), whereas idiopathic pulmonary fibrosis (IPF) is a diagnosis requiring …



BBT-877, a Novel Autotaxin Inhibitor, Abrogates Drug Resistance in Epithelial Ovarian Cancer Stem Cells

JS Kim, MJ Shin, SY Lee, SM Choi, KU Choi, DS Suh… - Anticancer Research, 2024

… BBT-877 is a novel ATX inhibitor used in clinical treatment of idiopathic pulmonaryfibrosis. However, the effects of BBT-877 on drug resistance and metastasis in ovarian CSCs remain unknown. In this study, we aimed to investigate …

  • 新規オートタキシン阻害剤BBT-877は上皮卵巣がん幹細胞の薬剤耐性を無効にする



[PDF] Cluster analysis identifies novel real-world lung disease-pulmonary hypertension sub-phenotypes: implications for treatment response

SW Johnson, RS Wang, MR Winter, KR Gillmeyer… - ERJ Open Research, 2024

… Right ventricular systolic pressure by echocardiography as a predictor of pulmonary hypertension in idiopathic pulmonary fibrosis. Respir … Prevalence and outcomes of pulmonary arterial hypertension in advanced idiopathic pulmonary

  • クラスター分析により、現実世界の肺疾患と肺高血圧症の新たなサブ表現型が特定: 治療反応への影響




 

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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。

当面、毎週アラートの内容をアップしていこうと思います。

 

癒しの音楽をお届けいたします。 

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