ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です！と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この１年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。
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24/03/22
Idiopathic Pulmonary Fibrosis Incidentally Detected by CT Scan as Interstitial Lung Abnormalities
T Bando, R Takei, J Fukihara, H Sasano, Y Yamano… - Annals of the American …, 2024
… In conclusion, patients with incidentally detected IPF, even those with preclinical IPF, had a similar FVC decline to those with clinical IPF. When an ILA is detected, it is desirable to evaluate the possibility of IPF and to consider early referral and …
- 偶然、CTスキャンで間質性肺異常として発見される特発性肺線維症、
[HTML] Association between nintedanib adherence trajectory and healthcare use among idiopathic pulmonary fibrosis patients
M Nili, AJ Epstein, D Nunag, A Olson, BJ Borah - BMC Pulmonary Medicine, 2024
… these relationships for patients with idiopathic pulmonary fibrosis (IPF) initiating nintedanib. … This analysis used 100% Medicare data and included beneficiaries with IPF who initiated … All-cause and IPF-related hospitalization events and total …
- 特発性肺線維症患者におけるニンテダニブアドヒアランスの軌跡と医療利用との関連性
[PDF] Acute Exacerbation of Idiopathic Pulmonary Fibrosis With Concurrent Cardiac Amyloidosis: A Technetium Pyrophosphate Study
T Yanagihara, H Hatashima, H Ogata, Y Moriuchi… - Cureus, 2024
… exacerbations of idiopathic pulmonaryfibrosis (IPF). In this report, we detail the case of a 73-year-old patient with acute exacerbation of IPF and … The therapeutic strategy for acute exacerbation of IPF encompassed methylprednisolone pulse …
Toll-Like Receptor 9 Aggravates Pulmonary Fibrosis by Promoting NLRP3-Mediated Pyroptosis of Alveolar Epithelial Cells
C Ren, Q Wang, S Fan, T Mi, Z Zhang, D He - Inflammation, 2024
… Gene expression microarray related to Idiopathic pulmonary fibrosis(IPF) was obtained from the Gene Expression Omnibus(GEO) database. In the mouse model of bleomycin-induced PF, adeno-associated virus(AAV6) was used to interfere with …
- Toll様受容体9はNLRP3を介した肺胞上皮細胞のピロトーシスを促進することにより肺線維症を悪化させる
Cystatin C and cystatin M/E: New regulators of the proteolytic balance in pulmonary fibrosis?
G Lalmanach, A David, R Allouche, B Rigoux… - Revue des Maladies …, 2024
… Pulmonary fibrosis (PF) is a chronic disease characterized by fibrous thickening in the interstitial spaces of the lung. Specifically, idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible PF of unknown etiology (median survival: 2–4 years) …
- シスタチン C およびシスタチン M/E: 肺線維症におけるタンパク質分解バランスの新しい調節因子?
TUDCA alleviates the worsening effect of intermittent hypoxia on pulmonary fibrosis
Z Ghlissi, L Haine, D Marchant, KDC Ferreira… - Revue des Maladies …, 2024
… associated with idiopathic pulmonaryfibrosis (IPF). Nocturnal Intermittent hypoxia (IH), the main pathogenic trait of OSA, has been shown to be a pejorative prognostic factor in IPF. Previous studies from our lab demonstrated that the severity of mouse …
- TUDCAは肺線維症に対する断続的な低酸素症の悪化効果を軽減
Anti-fibrotic effect of a FGF ligands trap in pulmonary fibrosis
D Gonçalves, C Scribe, P Dellugat, G Rignol, C Ghilain… - Revue des Maladies …, 2024
… Lung fibrosis, including idiopathic pulmonaryfibrosis (IPF), results from dysfunctional wound repair involving different cell types, including … In order to better understand the complex functions of FGFs on pulmonary fibrosis, we …
- 肺線維症におけるFGFリガンドトラップの抗線維化効果
[PDF] O‐GlcNAc regulates anti‐fibrotic genes in lung fibroblasts through EZH2
QP Wu, S Vang, JQ Zhou, S Krick, JW Barnes… - Journal of Cellular and …, 2024
… Epigenetic modifications are involved in fibrotic diseases, such as idiopathic pulmonaryfibrosis (IPF), … IPF or non-IPF lung fibroblasts with or without EZH2 inhibitor EZP6438, O-GlcNAc transferase (OGT) inhibitor (OSMI-1) or O-GlcNAcase (OGA) …
- O-GlcNAcはEZH2を介して肺線維芽細胞の抗線維化遺伝子を制御
Laryngeal Dysfunction Manifesting as Chronic Refractory Cough and Dyspnea Laryngeal Physiology in Respiratory Health and Disease
KM Sundar, A Stark, MJ Morris - CHEST, 2024
… cough in idiopathic pulmonary 338 fibrosis (IPF) is particularly high and significantly impacts quality of life70. The basis of chronic cough in 339 IPF is unclear and even though IPF … in IPFpatients to 341 capsaicin and mechanical …
24/03/18
[HTML] Identifying a survival-associated cell type based on multi-level transcriptome analysis in idiopathic pulmonary fibrosis
F Xu, Y Tong, W Yang, Y Cai, M Yu, L Liu, Q Meng - Respiratory Research, 2024
… Idiopathic pulmonary fibrosis (IPF) is a progressive disease with a five-year survival rate of less than 40%. There is significant variability in … Idiopathic pulmonary fibrosis (IPF) is a severe chronic interstitial lung disease [1]. IPFpatients …
- 特発性肺線維症におけるマルチレベルトランスクリプトーム解析に基づく生存関連細胞型の同定
[PDF] Potential role of SIRT-1 and SIRT-3 as biomarkers for the diagnosis and prognosis of idiopathic pulmonary fibrosis
F Perrotta, V D'Agnano, DF Mariniello, G Castaldo… - 2024
… Background: Idiopathic pulmonary fibrosis(IPF) is a debilitating and … including pulmonary fibrosis. Methods: A cross-sectional, prospective, observational single-center study was conducted to investigate the potential role of serum SIRTs levels as …
- 特発性肺線維症の診断および予後におけるバイオマーカーとしての SIRT-1 および SIRT-3 の潜在的な役割
[PDF] Interstitial lung diseases: never forget to think about it in primary care
G Bermudo, M Roman-Rodriguez, M Molina-Molina - Expert Review of Respiratory …, 2024
… Idiopathic pulmonary fibrosis (IPF) is the most lethal and frequent fibrotic ILD. But many other non-IPF fibrotic ILDs may present a similar disease behavior to IPF … factors have been identified in idiopathic interstitial pneumonias, including IPF. The …
- 間質性肺疾患: プライマリケアで考慮することを忘れないでください
[PDF] Trillin Protects Against Bleomycin-Induced Pulmonary Fibrosis via Suppressing Oxidative Stress and IL-1β/NLRP3 Inflammasome Positive Cycle
X Li, S Wei, S Liu, S Xie, J Liu, Y Yang, Y Chen… - Natural Product …, 2024
… Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterized by chronicity, progressiveness, and fibrosis. Unfortunately, IPF … Current guidelines recommend pirfenidone and nintedanib as treatments for IPF due to their pleiotropic …
- トリリンは酸化ストレスとIL-1β/NLRP3インフラマソーム陽性サイクルを抑制することでブレオマイシン誘発性肺線維症を防ぐ
[HTML] Insights into Disease Progression of Translational Preclinical Rat Model of Interstitial Pulmonary Fibrosis through Endpoint Analysis
AH Kadam, JE Schnitzer - Cells, 2024
… Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease characterized by … Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease characterized by the … Persistent injury leads to the development of …
- エンドポイント分析による間質性肺線維症のトランスレーショナル前臨床ラットモデルの疾患進行に関する洞察
[HTML] Clinical characteristics and outcome of lung cancer in patients with fibrosing interstitial lung disease
SJ Han, HH Kim, D Hyun, W Ji, CM Choi, JC Lee… - BMC Pulmonary Medicine, 2024
… idiopathic pulmonary fibrosis (IPF) and non-IPF ILD … Idiopathic pulmonary fibrosis(IPF), the most common type of fibrosing ILD, is a type of chronic and progressive disease of unknown cause [3] with a median survival of 3–5 years from …
- 線維化性間質性肺疾患患者における肺がんの臨床的特徴と転帰
[PDF] New Updates in Sarcoidosis Research: Defining and Renewing the Quest
CA Bonham, M Sharp - American Journal of Physiology-Lung Cellular and …, 2024
… shared genetic risk factors with idiopathicpulmonary fibrosis. Like some forms 19 of familial pulmonary fibrosis, patients with fibrotic … results are exciting and support hypotheses 22 that progressive pulmonary fibrosis (PPF) shares biological factors …
- サルコイドーシス研究の新たな最新情報: 探求の定義と更新
[PDF] Automating literature search and integrating meta-GWAS and eQTL data to uncover variants of interest in IPF
E Croot - 2024
… In the second part of this project, meta-GWAS and eQTL data were integrated to uncover variants of interest in the lung disease idiopathicpulmonary fibrosis (IPF). IPF is a lung disease with poor prognosis, increasing diagnosis rates, and limited …
- 文献検索を自動化し、メタ GWAS データと eQTL データを統合して、IPF で関心のあるバリアントを明らかにする
[PDF] A novel therapy for intractable chronic cough
M Bricknell, CZF Zhao, N Smallwood, N Goh - Respirology Case Reports, 2024
… A 67-year-old never-smoking woman with idiopathic pulmonary fibrosis (IPF), was referred with progressive debilitating chronic cough for several … She was diagnosed with IPFafter multi-disciplinary team discussion. She was subsequently …
- 難治性の慢性咳嗽に対する新たな治療法
24/03/17
[PDF] Advancing Drug Development in Idiopathic Pulmonary Fibrosis: Tomorrow Is Now
YH Khor, CJ Ryerson - American Journal of Respiratory and Critical Care …, 2024
… and pirfenidone slow progression of idiopathic pulmonary fibrosis (IPF) has sparked further … -2, zinpentraxin alfa, in 664 patients with IPF (2). Although study enrolment was complete, the … The STARSCAPE trial adds another failed …
- 特発性肺線維症における医薬品開発の進歩: 明日は今です
Japanese guidelines for the treatment of idiopathic pulmonary fibrosis 2023: Revised edition
M Bando, S Homma, H Date, K Kishi, H Yamauchi… - Respiratory Investigation, 2024
… Idiopathic pulmonary fibrosis (IPF) has the poorest prognosis among idiopathic interstitial pneumonias (IIPs), with no established standard treatment. With respect to the treatment of IPF, an international consensus statement [1] concerning the …
- 特発性肺線維症治療ガイドライン2023年版 改訂版
[PDF] Current and Novel Treatment Modalities of Idiopathic Pulmonary Fibrosis
M Arshad, ZM Athar, T Hiba - Cureus, 2024
… Idiopathic pulmonary fibrosis (IPF) presents a clinical challenge characterized by progressive fibrosis and destruction of lung tissue. Despite recent advancements, including antifibrotic medications like pirfenidone and nintedanib, IPF … Idiopathic …
- 特発性肺線維症の現在および新規の治療法
Phase 2, Double-Blind, Placebo-controlled Trial of a c-Jun N-Terminal Kinase Inhibitor in Idiopathic Pulmonary Fibrosis
WLLD Mattos, N Khalil, LG Spencer, F Bonella, RJ Folz… - American Journal of …, 2024
… Idiopathic pulmonary fibrosis (IPF) is a progressive … IPF (4, 5), but they do not halt or reverse the decline in lung function (2, 3). In addition, both therapies are associated with adverse events (AEs) that can lead to treatment discontinuation or …
- 特発性肺線維症におけるc-Jun N末端キナーゼ阻害剤の第2相二重盲検プラセボ対照試験
Idiopathic pulmonary fibrosis: Desperately seeking a model
N Hennion, C Chenivesse, S Humez, F Gottrand… - Revue des Maladies …, 2024
… Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and fatal lung disease of which the origin and development mechanisms … of IPF. The aim of this mini-review is to provide an overview of the most commonly used experimental …
- 特発性肺線維症: 必死のモデル探し
Patients with idiopathic pulmonary fibrosis and refractory cough have traction bronchiectasis and distorted airway architecture: a retrospective case review study
K Yamamura, J Hara, S Watanabe, T Kobayashi… - Journal of Thoracic Disease
Patients with idiopathic pulmonary fibrosisand refractory cough have traction bronchiectasis and distorted airway architecture: a retrospective case review study - Yamamura - Journal of Thoracic Disease … Patients with idiopathicpulmonary …
- 特発性肺線維症と難治性咳嗽の患者には牽引性気管支拡張症と気道構造の歪みがある：遡及的症例レビュー研究
Adoptive Transfer of CD49a+ Tissue Resident memory cells reverses pulmonary fibrosis in mice.
SL Collins, Y Chan-Li, K Shenderov, AM Nelson… - bioRxiv, 2024
… with idiopathic pulmonary fibrosis (IPF) results in the down regulation of IPF fibroblast collagen production. Lastly, we demonstrate in human IPF lung histologic samples that CD49a+ CD4+ TRMs, which can down regulate human IPF fibroblast …
- CD49a+ 組織常駐記憶細胞の養子移植は、マウスの肺線維症を逆転させます。
The Role of Inflammation and Fibrosis in ILD Treatment Decisions
J Behr, ML Salisbury, SLF Walsh, AJ Podolanczuk… - American Journal of …, 2024
… Some ILDs have identifiable causes or associated conditions, while others are considered idiopathic. Idiopathic pulmonaryfibrosis (IPF) is a distinct ILD subtype defined by clinical, radiological, and histological criteria (1). Recently, a subgroup of …
- ILDの治療決定における炎症と線維症の役割
[PDF] A novel biomimetic probe for galectin‐3 recognition: Chemical synthesis and structural characterization of a β‐galactose branched sodium hyaluronate
S Nizzolo, E Esposito, MH Ni, L Bertocchi, G Bianchini… - Proteoglycan Research, 2024
… idiopathic pulmonary fibrosis (IPF), a rare disease characterized by rapid fibrosis progression leading to respiratory failure and death. HYLACH® is a HA derivative designed to bind specifically galectin-3 (Gal-3), a key protein in fibrosis documented …
Untreated Obstructive Sleep Apnea in Interstitial Lung Disease and Impact on Interstitial Lung Disease Outcomes
AS Melani, S Croce, M Messina, E Bargagli - Sleep Medicine Clinics, 2024
… Should we routinely screen patients with idiopathic pulmonary fibrosis for nocturnal hypoxemia?. … Disordered breathing during sleep and exercise in idiopathic pulmonaryfibrosis. … OSA is now identified as an important comorbidity …
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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
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