AIとIPFと癒しの音楽

特発性肺線維症 idiopathic pulmonary fibrosis (IPF)患者によるIPF関連学術情報の収集とシェア。癒しの音楽もお届けしています。

IPF Weekly Update

ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です!と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この1年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。

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24/03/15

 

[PDF] The Role of Proton Pump Inhibitors in the Realm of Idiopathic Pulmonary Fibrosis and its Associated Comorbidities: A Systematic Review

S Iftikhar, SF Alhaddad, CN Paulsingh, MF Riaz… - Cureus, 2024

… As the global incidence of idiopathicpulmonary fibrosis (IPF) is on the rise, … ) in IPF and answers the question, “Does proton pump inhibitor improve only the prognosis of gastroesophageal associated idiopathicpulmonary fibrosis or for other …

  • 特発性肺線維症およびその関連併存症の領域におけるプロトンポンプ阻害剤の役割:系統的レビュー



[PDF] Immunological Similarities and Differences between Post-COVID-19 Lung Sequelae and Idiopathic Pulmonary Fibrosis

S Gangi, L Bergantini, P Cameli, I Paggi, M Spalletti… - Biomedicines, 2024

… The expression of PD-1 and TIGIT was abundant on T and NK cell subsets of the two lung fibrotic groups, IPF … of pulmonaryfibrosis, idiopathic and secondary to SARS-CoV-2 infection. We observed a significant imbalance not only in CD4, CD8 …



Mesenchymal stem cells-derived exosomes carrying microRNA-30b confer protection against pulmonary fibrosis by downregulating Runx1 via Spred2

L Zhu, Y Xu, J Wang, Y Zhang, J Zhou, H Wu - Molecular Genetics and Genomics, 2024

Idiopathic pulmonary fibrosis (IPF) is a chronic pulmonary fibrosis disease that is fatal. Mesenchymal stem cells (MSCs)-secreted … IPFwho underwent pulmonary transplantation. This suggests that miR-30b plays an important role in both the …

  • マイクロRNA-30bを運ぶ間葉系幹細胞由来のエクソソームは、Spred2を介してRunx1を下方制御することにより肺線維症に対する防御を与える



[PDF] Regulation of Interstitial Lung Diseases by Pulmonary Endothelial Cells via PLVAP

X Zhang, L Jia, R Hou, Y Zhao, L Zhang, X Tong, Y Mo… - bioRxiv, 2024

… for Idiopathic Pulmonary Fibrosis (IPF) and non- 2 IPF progressive fibrotic interstitial lung diseases (non-IPF-PF) highlights the need for 3 identifying common therapeutic targets. We utilize single-cell RNA sequencing data 4 from six disease …

  • PLVAP を介した肺内皮細胞による間質性肺疾患の制御



[PDF] Inhibition of fatty acid synthase in fibroblasts alleviates pulmonary fibrosis through the regulation of β-catenin

H Lian, R Wan, K Yang, S Ma, Y Wang, K Xu, L Cheng… - 2024

Idiopathic pulmonary brosis (IPF) is a progressive and fatal interstitial lung disease with poor therapeutic options while the pathogenesis keeps elusive. Herein we demonstrated that the expression of FASN was increased in broblasts of IPF

  • 線維芽細胞における脂肪酸合成酵素の阻害は、β-カテニンの制御を通じて肺線維症を軽減



Sumatriptan Mitigates Bleomycin-induced Lung Fibrosis in Male Rats: Involvement of Inflammation, Oxidative Stress and α-SMA

A Bahramifar, RM Jafari, M Sheibani, MA Manavi… - Tissue and Cell, 2024

Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung condition that produces symptoms including coughing which may cause by excessive … of serotonin, playing a pivotal role in regulating both inflammation and oxidative stress which is …

  • スマトリプタンは雄ラットのブレオマイシン誘発肺線維症を軽減:炎症、酸化ストレス、α-SMAの関与



H Yu, X Zhang, B Wen, S Hu, B Ni - All Life, 2024

… the usage of statin therapy in lung diseases like idiopathic pulmonary fibrosis (IPF) (Richeldi et al. Citation2014; Kang et al. Citation2021). … evidence to conclude the effect of statin therapy on disease-related outcomes in IPF (Kim et al. Citation2021 …

  • 脂質低下薬の標的と肺関連疾患: メンデルランダム化研究



[HTML] The lungs

P Scrivani, T Schwarz, T Liuti - BSAVA Manual of Canine and Feline Thoracic …, 2024

… High-resolution dorsal thoracic CT image through the dorsal part of the lungs of a 13-year-old West Highland White Terrier with idiopathicpulmonary fibrosis. In the cranial aspect of the left lung, there is a small (4 mm) soft tissue nodule (arrowed) …



24/03/08

 

[HTML] Exosomal circRNAs in the plasma serve as novel biomarkers for IPF diagnosis and progression prediction

W Gan, W Song, Y Gao, X Zheng, F Wang, Z Zhang… - Journal of Translational …, 2024

… circRNAs in idiopathic pulmonary fibrosis(IPF). Therefore, identifying the differentially-expressed exosomal circRNAs in IPF could provide … prediction in patients with IPF. Initially, we investigated the expression profile of circRNAs in …

  • 血漿中のエクソソームcircRNAはIPFの診断と進行予測のための新規バイオマーカーとして機能





[HTML] Drug-Gene Risk Stratification in Patients with Suspected Drug-Induced Interstitial Lung Disease

M Drent, PA Wijnen, NT Jessurun, AM Harmsze… - Drug Safety, 2024

… The causes of fibrotic ILD vary from identifiable causes, including autoimmune or exposure-related causes, to those classified as idiopathic, ie., idiopathic interstitial pneumonias [1]. The pathological pattern, usual interstitial pneumonia or idiopathic

  • 薬剤誘発性間質性肺疾患が疑われる患者における薬剤遺伝子リスク層別化




24/03/12

 

[PDF] Transcriptomics in Idiopathic Pulmonary Fibrosis Unveiled: A New Perspective from Differentially Expressed Genes to Therapeutic Targets

W Hu, Y Xu - Frontiers in Immunology, 2024

… This study provides a detailed analysis of Idiopathic Pulmonary Fibrosis, identifying 459 key genes and pathways using advanced bioinformatics and statistical methods. It 460 emphasizes the importance of immune cells and genetic …

  • 特発性肺線維症におけるトランスクリプトミクスの解明: 発現差のある遺伝子から治療標的までの新たな視点



Association Between High Levels of Nitrogen Dioxide and Increased Cumulative Incidence of Lung Cancer in Patients with Idiopathic Pulmonary Fibrosis

HY Yoon, SY Kim, JW Song - European Respiratory Journal, 2024

… of idiopathic pulmonary fibrosis (IPF) with a poor prognosis. However, the association between individual exposure to air pollutants and lung cancer development in patients with IPF is … Idiopathic pulmonary fibrosis (IPF) is a chronic …

  • 特発性肺線維症患者における高レベルの二酸化窒素と肺がんの累積発生率の増加との関連




[PDF] A Long and Winding Road: Drug Development in Idiopathic Pulmonary Fibrosis

P Spagnolo, TM Maher - American Journal of Respiratory and Critical Care …, 2024

Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive fibrotic lung disease of unknown origin associated with high morbidity, … systems biology of pulmonary fibrosis, the inefficiency of current IPF trial design and endpoints and the …

  • 長く曲がりくねった道: 特発性肺線維症の薬剤開発



[HTML] Age at menarche and idiopathic pulmonary fibrosis: a two-sample mendelian randomization study

J Cao, Y Ma, W Zhao, C Feng - BMC Pulmonary Medicine, 2024

… Sex difference in the incidence rate of idiopathic pulmonary fibrosis (IPF) indicates that estrogen has a certain protective effect on the … , and IPF. Our study intended to employ Mendelian randomization (MR) method to elucidate the causal …

  • 初経年齢と特発性肺線維症:2サンプルのメンデルランダム化研究



[PDF] Exploring the role and association of monocytes with progression of Idiopathic Pulmonary Fibrosis

AKN Achaiah - 2024

… : Idiopathic pulmonary fibrosis (IPF) is a chronic fibroproliferative disease characterised by accumulation of scar tissue within the lung parenchyma. The clinical course of IPFIdiopathic Pulmonary fibrosis (IPF) is a chronic progressive

  • 単球の役割と特発性肺線維症の進行との関連性を探る



[PDF] Treatment patterns and patient journey in progressive pulmonary fibrosis: a cross-sectional survey

N Chaudhuri, P Spagnolo, C Valenzuela, VC Amatto… - 2024

Idiopathic pulmonary brosis (IPF), the archetypal progressive brosing ILD (PF-ILD) and the most common idiopathic interstitial pneumonia, … Approximately one third of patients with brosing ILDs other than IPF may experience disease progression, de …

  • 進行性肺線維症における治療パターンと患者の経過: 横断的調査



TB and interstitial lung disease: a systematic review and meta-analysis

M Rezaee, N Azizi, B Danaei, A Davari… - The International Journal of …, 2024

… In the subgroup analysis, the TB rate among patients with silicosis and idiopathic pulmonaryfibrosis (IPF) was respectively 35.6% (95% CI … studies with idiopathic pulmonary fibrosis(IPF).The remaining three articles described patients with …

  • 結核と間質性肺疾患:系統的レビューとメタ分析



Glasgow prognostic score and body mass index predict short-term discontinuation of the antifibrotic agents pirfenidone and nintedanib

K Takehara, Y Koga, Y Hachisu, M Utsugi, Y Sawada… - Respiratory Investigation, 2024

… The antifibrotic agents pirfenidone and nintedanib have been shown to be effective in patients with idiopathic pulmonary fibrosis(IPF). However, discontinuation of antifibrotic drugs is a major clinical concern because of the lack of …

  • グラスゴー予後スコアとBMIは、抗線維化剤ピルフェニドンとニンテダニブの短期中止を予測 



Bibliometric and Visual Analysis of Fibrotic Pulmonary Sarcoidosis

N WEI, X Fang, X Zhao, F Zeng, C Yu, NTT Huyen, F Li… - 2024

… Current hot research topics mainly include FPS-relevant diseases (interstitial lung disease, idiopathic pulmonary fibrosis and pulmonaryfibrosis), complications (pulmonary hypertension, chronic obstructive pulmonary disease, and lung cancer), commonly …

  • 線維性肺サルコイドーシスの書誌学的および視覚的分析



[PDF] An in vivo screening platform identifies senolytic compounds that target p16 INK4a+ fibroblasts in lung fibrosis

JY Lee, NS Reyes, S Ravishankar, M Zhou… - The Journal of Clinical …, 2024

… fibroblasts isolated from patients with idiopathic pulmonary fibrosis (IPF), and reduced 13 p16INK4a+ fibroblasts from IPFPCLS ex vivo. This study provides proof of concept for a 14 … histologic evidence of p16INK4a+ cells in IPF and animal …

  • in vivo スクリーニングプラットフォームは、肺線維症における p16 INK4a+ 線維芽細胞を標的とする老化細胞破壊化合物を特定



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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。

当面、毎週アラートの内容をアップしていこうと思います。

 

癒しの音楽をお届けいたします。 

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