ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です！と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この１年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。
<><><>
<>
24/08/30
[HTML] The burden of cough in idiopathic pulmonary fibrosis and other interstitial lung diseases: a systematic evidence synthesis
R Green, M Baldwin, N Pooley, K Misso, MPMH Mölken… - Respiratory Research, 2024
Cough remains a persistent symptom in patients with idiopathic pulmonary fibrosis (IPF) and other interstitial lung diseases (ILDs). To inform future research, treatment and care models, we conducted the first systematic synthesis of evidence on its …
- 特発性肺線維症およびその他の間質性肺疾患における咳嗽の負担：系統的エビデンス統合
Establishment of prognostic model for severe primary graft dysfunction in patients with idiopathic pulmonary fibrosis after lung transplantation
Z SONG, T DAI, S GU, X LI, M HUANG, S TANG, C HU… - Organ Transplantation, 2024
… (PGD) in patients with idiopathic pulmonaryfibrosis (IPF) after lung transplantation. Methods Clinical data of 226 IPF patients who underwent lung … The overall prediction performance of each model is similar, which may predict the risk of grade …
- 特発性肺線維症患者における肺移植後の重篤な一次移植片機能不全の予後モデルの確立
Toll-like Receptor 9 Inhibition Mitigates Fibroproliferative Responses in Translational Models of Pulmonary Fibrosis
G Trujillo, A Regueiro-Ren, C Liu, B Hu, Y Sun… - American Journal of …, 2024
… Scientific Knowledge on the Subject: Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease for … : Idiopathic pulmonaryfibrosis (IPF) is a fatal lung disease for which current treatment options only slow clinical progression. Previously, we …
- Toll様受容体9阻害は肺線維症のトランスレーショナルモデルにおける線維増殖反応を軽減する
USP7 Promotes TGF-β1 Signaling by De-Ubiquitinating Smad2/Smad3 in Pulmonary Fibrosis
F Tang, H Gong, T Ke, W Yang, Y Yang, Z Liu - Discovery medicine, 2024
… in IPF, thereby providing novel insights for the diagnosis and management of IPF. Methods: We first detected the expression of USP7 in lung tissues of mice with Bleomycin (BLM)-induced pulmonary fibrosis … the effectiveness of USP7-specific …
- USP7 は肺線維症において Smad2/Smad3 を脱ユビキチン化することで TGF-β1 シグナル伝達を促進する
[PDF] A Scoping Review of Factor-Related Cognitive Impairment in Interstitial Lung Disease
H Annaka, K Honma, T Nomura - Cureus, 2024
… Particularly, idiopathic pulmonary fibrosis(IPF), which is an ILD with progressive pulmonary fibrosis, progresses rapidly and has a poor … /ERS/JRS/ALAT clinical practice guidelines for IPF and progressive pulmonaryfibrosis indicate that …
- 間質性肺疾患における因子関連認知障害のスコープレビュー
Triiodothyronine Acts on DAO to Regulate Pulmonary Fibrosis Progression by Facilitating Cell Senescence through the p53/p21 Signaling Pathway
X Guo, K Xu, L Wang, L Ding, W Li, W Zhao, X Zhang… - Frontiers in Pharmacology
… Idiopathic pulmonary fibrosis (IPF) is the result of multiple cycles of epithelial cell injury and fibroblast activation; currently, there is no clear etiology. Increasing evidence suggests that protein metabolism and amino acids play a crucial role in IPF …
- トリヨードチロニンはDAOに作用し、p53/p21シグナル伝達経路を介して細胞老化を促進し、肺線維症の進行を制御する
[PDF] Association between the cardiothoracic ratio on chest X-rays and the respiratory function in patients with interstitial lung diseases: A cross-sectional study
A Hagiwara, I Yamatani, R Kudoh, K Hiramatsu… - Internal Medicine, 2024
… A retrospective cohort study demonstrated that the percent VC (%VC) was a significant prognostic predictor in patients with idiopathicpulmonary fibrosis (IPF) (5). Although FVC is generally smaller than VC in patients with asthma and chronic …
- 間質性肺疾患患者における胸部X線上の心胸郭比と呼吸機能との関連性：横断的研究
[PDF] Lipid-based drug delivery systems for inflammatory and fibrosis therapies
M Carone
… The second unit addresses the scarcity of effective antifibrotic therapies, specifically targeting idiopathic pulmonary fibrosis. Investigational use of pirfenidone (PFD) across organs showed promise, leading to the development of ultra-high …
- 炎症および線維症治療のための脂質ベースの薬物送達システム
24/08/29
[HTML] Automated 3D-Body Composition Analysis as a Predictor of Survival in Patients With Idiopathic Pulmonary Fibrosis
L Salhöfer, F Bonella, M Meetschen, L Umutlu… - Journal of Thoracic Imaging, 2024
… Purpose: Idiopathic pulmonary fibrosis(IPF) is the most common interstitial lung disease, … muscle mass in patients with idiopathic pulmonary fibrosis according to a multidisciplinary … changes in idiopathicpulmonary fibrosis and idiopathic …
- 特発性肺線維症患者の生存予測因子としての自動 3D 体組成分析
Imaging Pulmonary Fibrosis and Treatment Efficacy In Vivo with Autotaxin-Specific PET Ligand [18F] ATX-1905
X Deng, J Liu, J Zhou, Y Shi, S Song, J Chen, Y Li… - Molecular Pharmaceutics, 2024
… Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by unpredictable progression and limited therapeutic options. Current diagnosis relies on high resolution computed tomography (HRCT), which may not adequately …
- オートタキシン特異的PETリガンド[18F] ATX-1905を用いた肺線維症および治療効果の生体内画像化
[HTML] Causal associations of obstructive sleep apnea with Chronic Respiratory Diseases: a Mendelian Randomization study
PY Hong, D Liu, A Liu, X Su, XB Zhang, YM Zeng - BMC Pulmonary Medicine, 2024
… idiopathic pulmonary fibrosis (IPF). Data were sourced from the FinnGen Consortium (OSA, n = 375,657) and UK Biobank, focusing on genome-wide associations between single-nucleotide polymorphisms (SNPs) and the diseases …
- 閉塞性睡眠時無呼吸と慢性呼吸器疾患の因果関係：メンデルランダム化研究
Iron-laden macrophage-mediated paracrine pro-fibrotic signaling induces lung fibroblast activation
Y Li, X Du, Y Hu, D Wang, L Duan, H Zhang, R Zhang… - American Journal of …, 2024
… Idiopathic pulmonary fibrosis (IPF) is a devastating condition characterized by 31 progressive lung scarring and uncontrolled fibroblast … during pulmonary fibrosis using both 37 in vivo and in vitro approaches. In murine bleomycin- and amiodarone-induced …
- 鉄を含んだマクロファージを介した傍分泌線維化促進シグナル伝達が肺線維芽細胞の活性化を誘導する
[HTML] Clinical implications of nintedanib pharmacokinetics in patients with pulmonary fibrosis
BC Agema, M Berrich, L Seuren, SDT Sassen… - Biomedicine & …, 2024
… Nintedanib is used to treat both idiopathicand progressive pulmonary fibrosis (IPF/PPF). Evidence of both an exposure-response relationship and an exposure-toxicity relationship has been found, suggesting the potential value of therapeutic drug …
- 肺線維症患者におけるニンテダニブの薬物動態の臨床的意義
PDE4B inhibition by nerandomilast: Effects on lung fibrosis and transcriptome in fibrotic rats and on biomarkers in human lung epithelial cells
D Reininger, K Fundel-Clemens, CH Mayr, L Wollin… - British journal of pharmacology
… relevant parameters of idiopathic pulmonaryfibrosis (IPF; lung … of pulmonary fibrosiswere analysed by next-generation sequencing (NGS). Data were matched with public domain data derived from human IPF samples to investigate how well the …
- ネランドミラストによるPDE4B阻害：線維化ラットの肺線維症およびトランスクリプトーム、ならびにヒト肺上皮細胞のバイオマーカーへの影響
24/08/27
Differences in Healthcare and Palliative Care Utilization at the End of Life: a Comparison Study Between Lung Cancer, COPD, and IPF
AO Suen, K Bischoff, AS Iyer, K Radhakrishnan… - CHEST, 2024
… Background: Patients with lung cancer, idiopathic pulmonary fibrosis (IPF), and chronic obstructive pulmonary disease (COPD) have high … have been adopted in COPD and IPF care. Research Question: Do patients with COPD and IPF have …
- 終末期の医療と緩和ケアの利用の違い：肺がん、COPD、IPFの比較研究
24/08/26
[HTML] Clinical implications of six-minute walk test in patients with idiopathic pulmonary fibrosis: a retrospective cohort study
MJ Kim, SD Nathan, HH Kim, HC Kim - Therapeutic Advances in Respiratory Disease, 2024
Background: A six-minute walk test (6MWT) is a reproducible, easily performed test, and is widely used to determine functional exercise capacity in patients with idiopathic pulmonary fibrosis(IPF). However, there is currently a paucity of data on …
- 特発性肺線維症患者における6分間歩行テストの臨床的意義：後ろ向きコホート研究
[PDF] Lung cell transplantation for pulmonary fibrosis
I Milman Krentsis, Y Zheng, C Rosen, SY Shin… - Science Advances, 2024
… Idiopathic pulmonary fibrosis (IPF) has an estimated prevalence of 13 to 20 per 100,000 people worldwide. About 100,000 people are affected in the United States, and 30,000 to 40,000 new cases are diagnosed each year (World Health …
- 肺線維症に対する肺細胞移植
[PDF] Diagnostic Value of Serum KL-6 in Interstitial Lung Diseases
L Zuo, W Zhang, Y Wang, X Qi - International Journal of General Medicine, 2024
… more than 200 types of diseases, including idiopathic interstitial pneumonias (IIPs), collagen … further classified into several types, including idiopathic pulmonary fibrosis (IPF), as well as usual … develop into pulmonaryfibrosis or honeycomb lung …
- 間質性肺疾患における血清KL-6の診断価値
24/08/25
Idiopathic pulmonary fibrosis mortality: update on trends in the modern treatment era
AJ Podolanczuk, G Raghu - European Respiratory Journal, 2024
… A downward trend of mortality rates in patients with IPF in the modern treatment era https://bit.ly/3Y1XJcb Idiopathic pulmonaryfibrosis (IPF… Studies indicate that the global incidence and prevalence of IPF are increasing [2–8]. The reasons for this …
- 特発性肺線維症による死亡率：現代治療時代の最新動向
Deciphering the role of oxidative stress genes in idiopathic pulmonary fibrosis: a multi-omics mendelian randomization approach
X Liu, D Zhang, F Zhao, S Li, H Zhu, X Zhang - Genes & Immunity, 2024
Oxidative stress (OS) is crucial in idiopathicpulmonary fibrosis (IPF) pathogenesis, with its genes potentially acting as both causes and consequences of the disease. We identified OS-related genes from GeneCards and performed a meta-analysis on …
- 特発性肺線維症における酸化ストレス遺伝子の役割の解明：マルチオミクスメンデルランダム化アプローチ
[HTML] Investigation of Aberrant Basaloid Cells in a Rat Model of Lung Fibrosis
E Bocchi, V Pitozzi, S Pontis, PL Caruso, S Beghi… - Frontiers in Bioscience …, 2024
… Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung disease (ILD) whose cause and pathogenesis are not yet well understood. Until now, no animal model of lung fibrosis succeeds in recapitulating all IPF … Idiopathic …
- ラット肺線維症モデルにおける異常な基底細胞に関する研究
Lung fibrosis in sarcoidosis. Is there a place for antifibrotics?
KK Bączek, WJ Piotrowski - Frontiers in Pharmacology
… in idiopathic pulmonary fibrosis (IPF) and systemic sclerosis-related interstitial lung disease (SSc-ILD), has shown promise in patients with various progressive fibrosing interstitial lung diseases (PF-ILD), including those with sarcoidosis …
- サルコイドーシスにおける肺線維症。抗線維化薬は有効か？
<>
<><><>
特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
###
