ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です！と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この１年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。
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23/08/19
Long-circulating thiolated chitosan nanoparticles of nintedanib with N-acetyl cysteine for treating idiopathic pulmonary fibrosis: In vitro assessment of cytotoxicity …
S Singh, S Wairkar - International Journal of Pharmaceutics, 2023
… to treat idiopathic pulmonary fibrosis (IPF). This study aimed to formulate a long-circulating injection of Nintedanib to treat bedridden patients with IPF. Nintedanib … Therefore, NAC-NIN-NP could be a promising treatment option for IPFpatients and can be …
- 特発性肺線維症治療のためのN-アセチルシステインを含むニンテダニブの長期循環チオール化キトサンナノ粒子：細胞毒性、抗酸化物質、および抗線維化の可能性のin vitro評価
[PDF] Three-Dimensional Fractal Analysis of Idiopathic Pulmonary Fibrosis
W Wright
… The characterization of lung tissue architecture in Idiopathic Pulmonary Fibrosis(IPF) can … and peripheral fibrosis in the BLM groups, consistent with IPF. Due to our small sample size of only … prove to be an effective mode for differentiating and/or …
- 特発性肺線維症の三次元フラクタル解析
Inhaled nintentanib, pirfenidone and macitentan for pulmonary fibrosis: a laboratory experiment
P Zarogoulidis, D Petridis, H Huang, C Bai… - Therapeutic Delivery, 2023
… Aim: Idiopathic pulmonary fibrosis is a rare disease with few efficient drugs in the market. The consequences of this disease are mainly respiratory failure and pulmonary hypertension. Materials & methods: In our experiment we used the drugs …
- 肺線維症に対する吸入ニンテンタニブ、ピルフェニドン、マシテンタン: 室内実験
Exploring the Therapeutic Effects of Synthetic, Semi-synthetic and Naturally Derived Compounds Against Cancer
L Feng, J Gu, Y Yang, B Yang, R Shi - Frontiers in Pharmacology
… In a case report study by Shen et al., they described a rare case of idiopathic pulmonaryfibrosis associated with the use of nab-paclitaxel and carboplatin in ovarian cancer. During treatment, it is necessary to maintain a high level of vigilance …
- 合成、半合成、天然由来の化合物のがんに対する治療効果の探求
23/08/17
[PDF] Worldwide Idiopathic Pulmonary Fibrosis Prevalence
KR Dudhat - Morbidity and Mortality. International Journal of Clinical …, 2023
… Idiopathic Pulmonary Fibrosis The morphologic spectrum that has historically been referred to as IPF includes four histologically different types of idiopathic … and GIP are excluded from the IPF category since they are typically not idiopathic; …
- 世界的な特発性肺線維症の有病率
A fibroblast-dependent TGFβ1/sFRP2 noncanonical Wnt signaling axis underlies epithelial metaplasia in idiopathic pulmonary fibrosis
ML Cohen, AN Brumwell, TC Ho, G Montas, JA Golden… - bioRxiv, 2023
… TGFβ1 signaling in ILD, the therapeutic potential of EGCG in reducing IPF-related transcriptional changes, and identify the TGFβ1-non-canonical Wnt pathway crosstalk via sFRP2 as a novel mechanism for dysfunctional epithelial signaling in …
- 特発性肺線維症における上皮化生の根底にある線維芽細胞依存性のTGFβ1/sFRP2非標準的Wntシグナル伝達軸
[PDF] ANT1 and the SASP: Beyond the Bioenergetic Void
S Rangarajan - American Journal of Respiratory Cell and Molecular …, 2023
… Abnormal lung aging in chronic obstructive pulmonary disease and idiopathic pulmonaryfibrosis. Am J Respir Crit Care Med 2012; 186: 306-313… Mitochondria dysfunction and metabolic reprogramming as drivers of idiopathic pulmonary fibrosis …
- ANT1 と SASP: 生体エネルギーの空白を超えて
Association between chronic lung diseases and the risk of lung cancer in UK Biobank: observational and Mendelian randomization analyses
J Zhang, ZM Ma, H Wang, YT Fu, C Ji, M Zhu, HB Shen… - Zhonghua yu fang yi xue za …, 2023
… obstructive pulmonary disease and idiopathicpulmonary fibrosis were associated with the … obstructive pulmonary disease and idiopathicpulmonary fibrosis were associated with the … scores for chronic obstructive pulmonary disease and …
- 英国バイオバンクにおける慢性肺疾患と肺がんリスクとの関連性：観察分析とメンデルランダム化分析
[PDF] The Role of Osteopontin in Respiratory Health and Disease
GI Barkas, OS Kotsiou - J. Pers. Med, 2023
… Idiopathic pulmonary fibrosis (IPF) is a destructive lung disease characterized by rapid progression leading to lung fibrosis [44]. It is the most common idiopathic … IPF leads to scarring of the lung parenchyma, which results in reduced quality of life …
- 呼吸器の健康と病気におけるオステオポンチンの役割
23/08/15
Elevated serum mitochondrial DNA levels were associated with the progression and mortality in idiopathic pulmonary fibrosis
Y Liang, S Fan, Y Jiang, T Ji, R Chen, Q Xu, Y Liu… - International …, 2023
… ) was implicated in idiopathic pulmonaryfibrosis (IPF), but the association between circulating mtDNA levels with clinical parameters in IPF was unclear. In this study, we investigate the relationship between serum mtDNA levels with the …
- 血清ミトコンドリア DNA レベルの上昇は、特発性肺線維症の進行と死亡率に関連していた
[HTML] Determinants of Daily Physical Activity Limitation in Patients with Idiopathic Pulmonary Fibrosis
M Sikora, D Jastrzębski, K Pilzak, G Osiadło, D Ziora… - Respiratory Physiology & …, 2023
The purpose of the study was to determine the level of physical fitness assessed based on the physiological parameters and intensity of daily physical activity (PA) of patients with idiopathicpulmonary fibrosis (IPF). Additionally, we aimed to determine …
- 特発性肺線維症患者における日常の身体活動制限の決定要因
A Manganese (Ⅱ) complex as high-order multiphoton fluorescent probe for detecting nitric oxide content change in idiopathic pulmonary fibrosis mice
L Liu, L Zhang, M Li, Y Li, Q Wang, X Wang, S Li… - Sensors and Actuators B …, 2023
… idiopathic pulmonary fibrosis (IPF) patients. In this work, a high-order multiphoton fluorescent probe FS-MnCl 2 is designed and synthesized for detecting NO level in mice model of IPF. … monitor changes in NO levels in living cells and IPF mice. This …
- 特発性肺線維症マウスにおける一酸化窒素含有量の変化を検出するための高次多光子蛍光プローブとしてのマンガン (II) 錯体
[PDF] Efficacy of N-acetylcysteine plus pirfenidone in the treatment of idiopathic pulmonary fibrosis: a systematic review and meta-analysis
XL Zhang, Y Cao, B Zheng - 2023
… Numerous studies have demonstrated the potential of pirfenidone to enhance the prognosis of patients a icted with idiopathic pulmonary brosis (IPF). Although N-acetylcysteine (NAC) is utilized as an antioxidant in IPF treatment, the combination of NAC and …
- 特発性肺線維症の治療におけるN-アセチルシステインとピルフェニドンの有効性：系統的レビューとメタアナリシス
Deciphering the underlying mechanisms of Sanleng-Ezhu for the treatment of idiopathic pulmonary fibrosis based on network pharmacology and single-cell RNA …
X Zhou, F Tan, S Zhang, T Zhang - Current computer-aided drug design
… Background: Idiopathic pulmonary fibrosis(IPF) is the most common type of interstitial lung disease. Although the combination of herbs Sanleng … Notably, we obtained 2 IPFsubgroups by contrasting the most significantly up- and down-regulated …
End-Stage Idiopathic Pulmonary Fibrosis Lung Microenvironment Promotes Impaired NK Activity
T Cruz, PA Agudelo Garcia, JA Chamucero-Millares… - The Journal of Immunology
… Idiopathic pulmonary fibrosis (IPF) is a fibrotic age-related chronic lung disease characterized by the accumulation of senescent cells. … of senescent cells in the IPF lung remains unknown. In this study, we characterized the NK phenotype in IPF …
- 末期特発性肺線維症 肺微小環境がNK活性低下を促進
Dysfunctional Epithelial Barrier Is Characterized by Reduced E‐Cadherin in Idiopathic Subglottic Stenosis
AJ Berges, R Ospino, L Mafla, S Collins, Y Chan‐Li… - The Laryngoscope, 2023
… Idiopathic subglottic stenosis (iSGS) is a rare disease of the upper airways characterized by pathologic narrowing of the subglottis and … a subset of patients who develop idiopathicpulmonary fibrosis (IPF), another fibroproliferative disease.In …
- 特発性声門下狭窄症における上皮バリアの機能不全はE-カドヘリンの減少によって特徴付けられる
Flavokawain A ameliorates pulmonary fibrosis by inhibiting the TGF-β signaling pathway and CXCL12/CXCR4 axis
T Xiao, D Gao, X Gu, Y Zhang, Y Zhu, Z Zhang, Y He… - European Journal of …, 2023
… effect of FKA on pulmonary fibrosis using an animal model of bleomycin-induced pulmonaryfibrosis and showed that FKA alleviated the development of pulmonary fibrosis in a dose-… IPF (idiopathic pulmonary fibrosis) is the most common form of …
- フラボカイン A は、TGF-β シグナル伝達経路と CXCL12/CXCR4 軸を阻害することにより肺線維症を改善します。
[HTML] Integrating bioinformatic resources to identify characteristics of rheumatoid arthritis-related usual interstitial pneumonia
Y Qiu, C Liu, Y Shi, N Hao, W Tan, F Wang - BMC genomics, 2023
… We use the keyword “rheumatoid arthritis” or “idiopathic pulmonary fibrosis” to search for gene expression profiling tested by microarray or high-throughput sequencing from the National Center for Biotechnology Information (NCBI) Gene …
- バイオインフォマティクスリソースを統合して関節リウマチ関連の通常の間質性肺炎の特徴を特定する
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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
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