AIとIPFと癒しの音楽

特発性肺線維症 idiopathic pulmonary fibrosis (IPF)患者によるIPF関連学術情報の収集とシェア。癒しの音楽もお届けしています。

IPF Weekly Update

ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です!と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この1年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。

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23/07/15

 

[HTML] Validation of the recording of idiopathic pulmonary fibrosis in routinely collected electronic healthcare records in England

A Morgan, RS Gupta, PM George, JK Quint - BMC Pulmonary Medicine, 2023

… are lacking for diseases such as idiopathicpulmonary fibrosis (IPF) which are largely managed in … Algorithms were developed based on the literature and IPF diagnostic guidelines using … A total of 17,559 individuals had a least one record …

  • 英国で定期的に収集される電子医療記録における特発性肺線維症の記録の検証   



Long-term exposure to low concentrations of air pollution and decline in lung function in people with idiopathic pulmonary fibrosis: Evidence from Australia.

Q Zheng, IA Cox, L Leigh, B de Graaff, FH Johnston… - Respirology (Carlton, Vic.), 2023

… Little is known about the association between ambient air pollution and idiopathic pulmonaryfibrosis (IPF) in areas with lower levels of exposure. We aimed to investigate the impact of air pollution on lung function and rapid progression of IPF in Australia. …

  • 特発性肺線維症患者における低濃度の大気汚染への長期曝露と肺機能の低下:オーストラリアでの証拠。  



… and weekly paclitaxel in combination with bevacizumab for the treatment of advanced non-small cell lung cancer complicated by idiopathic interstitial pneumonias: A …

M Omori, Y Minegishi, H Uruga, A Fukuizumi, K Isobe… - Respiratory Investigation, 2023

… In particular, patients with idiopathicpulmonary fibrosis (IPF) are at a higher risk of developing lung cancer than the general population, whose relative risk is reportedly 7–14 [[2], [3], [4], [5]]. However, acute exacerbation (AE) of IIPs, caused by …

  • 特発性間質性肺炎を合併した進行性非小細胞肺がんの治療のための、カルボプラチンおよび毎週のパクリタキセルとベバシズマブの併用:実現可能性研究   



Regional Pulmonary Morphology and Function: Photon-counting CT Assessment

SC Scharm, C Schaefer-Prokop, HB Winther… - Radiology, 2023

… In this study, interstitial lung disease, particularly idiopathic pulmonary fibrosis, again showed higher mean values for ventilation in comparison to other lung diseases. The higher demonstrated values of the post–COVID-19 condition group …

  • 肺の局所的な形態と機能: フォトンカウンティング CT 評価   



NMDA receptor activation induces damage of alveolar type II cells and lung fibrogenesis through ferroptosis

H Cheng, D Feng, X Li, L Gao, Y Qiu, X Liang, Y Zhou… - Biochimica et Biophysica …, 2023

Idiopathic pulmonary fibrosis (IPF) is a progressive and ultimately fatal interstitial lung … is considered a new light on the etiology of pulmonary fibrosis. Here, we observed that N-methyl d-… NMDAR inhibition reduced lung injury and pulmonary

  • NMDA受容体の活性化は肺胞II型細胞の損傷とフェロトーシスを介した肺線維形成を誘発する

 

23/07/13



[PDF] COVID-19 progression in hospitalized patients using follow-up in vivo CT and ex vivo microCT

H Beeckmans, M Vermant, C De Fays, A Sacreas… - 2023

… In vivo and ex vivo CT scans were also compared to non-COVID-19 ARDS and idiopathic pulmonary fibrosis (IPF) on the level of to assess differences in disease. We present this article in accordance with the STROBE reporting checklist (available …

  • 追跡調査の in vivo CT および ex vivo microCT を使用した入院患者における COVID-19 の進行   



Regional and Disease-Specific Glycosaminoglycan Composition and Function in Decellularized Human Lung Extracellular Matrix

E Hoffman, Y Song, F Zhang, L Asarian, I Downs… - Acta Biomaterialia, 2023

… , chronic obstructive pulmonary disease (COPD), and idiopathic pulmonary fibrosis(IPF) patients. Significant differences were observed in … IPF lungs. Binding of transforming growth factor β to CS was similar in all three groups but binding to …



[HTML] Atractylodin Ameliorates Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice

Z Wu, J Fu, S Zhang, Y Huang, J Xu, M Zhu, S Chen… - … Research-Modern Chinese …, 2023

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease. The commonly used drugs for the treatment of pulmonaryfibrosis can … whether it could provide a new idea for the treatment of IPF by reducing the inflammatory reaction …

  • アトラクチロジンはマウスのブレオマイシン誘発性肺炎症および線維症を改善する  





23/07/11

 

Recent advances in the genetics of idiopathic pulmonary fibrosis

P Spagnolo, JS Lee - Current Opinion in Pulmonary Medicine, 2023

… Genetics contributes substantially to the susceptibility to idiopathic pulmonary fibrosis(IPF). Genetic studies in sporadic and familial disease have identified several IPF-associated variants, mainly in telomere-related and surfactant protein …

  •  特発性肺線維症の遺伝学の最近の進歩   



ATAC-ing single nucleus in idiopathic pulmonary fibrosis: TWIST1 strives back for myofibroblasts

O Burgy, AA Mailleux - European Respiratory Journal, 2023

Idiopathic pulmonary fibrosis (IPF) is the most common form of pulmonary fibrosis and is defined as a specific form of chronic, progressive fibrosing interstitial pneumonia of unknown cause. IPF … The current paradigm suggests that IPF is a …

  • 特発性肺線維症における単核のATAC化:TWIST1は筋線維芽細胞を取り戻そうとする   



Transcriptomic and Proteomic Changes Driving Pulmonary Fibrosis Resolution in Young and Old Mice

J Weckerle, CH Mayr, K Fundel-Clemens, B Lämmle… - American Journal of …, 2023

… -induced pulmonary fibrosis in mice mimics major hallmarks of idiopathic pulmonaryfibrosis, … Idiopathic pulmonary fibrosis(IPF) is characterized by epithelial damage, excessive fibroblast … the Bleomycin model of pulmonary fibrosis

  • トランスクリプトームおよびプロテオームの変化が若年および老マウスの肺線維症の解決を促進する   



Anti-UBE2T antibody: A novel biomarker of progressive-fibrosing interstitial lung disease

M Ujike-Hikichi, Y Gon, T Ooki, T Morisawa… - Respiratory Investigation, 2023

… We investigated the utility of the anti-UBE2T antibody in diagnosing IPF and idiopathic fNSIP by enrolling healthy participants (n = 61), patients with IPF (n = 43), and fNSIP (n = 21) (Fig. 1). The patients' baseline characteristics are presented in Table 1. …

  • 抗 UBE2T 抗体: 進行性線維化性間質性肺疾患の新規バイオマーカー   



Boosting therapeutic efficacy of mesenchymal stem cells in pulmonary fibrosis: The role of genetic modification and preconditioning strategies

M Mehrabani, S Mohammadyar, MA Rajizadeh… - Iranian Journal of Basic …, 2023

Idiopathic pulmonary fibrosis (IPF) is the most prevalent form of PF, with no reasonable etiology. However, some factors are believed to be behind the etiology of PF, including prolonged administration of several medications (eg, bleomycin and …

  • 肺線維症における間葉系幹細胞の治療効果の増強:遺伝子改変とプレコンディショニング戦略の役割   



[HTML] Learnings from clinical trials in patients with connective tissue disease-associated interstitial lung disease

JPH Sevilla, A Memon, M Hinchcliff - Arthritis Research & Therapy, 2023

Idiopathic pulmonary fibrosis (IPF) has the most evidence to guide therapy. Antifibrotic therapy showed benefit in slowing progression of IPF as assessed by pulmonary function tests (PFTs) [10, 11]. The combination of prednisone and …



[HTML] Nicotinamide N-methyltransferase Mediates Lipofibroblast-Myofibroblast Transition and Apoptosis Resistance

M Rehan, B Deskin, AR Kurundkar, S Yadav… - Journal of Biological …, 2023

… In this report, we demonstrate that NNMT is upregulated in human fibrotic disorders, specifically idiopathic pulmonary fibrosis(IPF), and is induced by TGF-β1 in human lung fibroblasts. Our studies indicate that NNMT functions as a critical …

  • ニコチンアミド N-メチルトランスフェラーゼは脂肪線維芽細胞から筋線維芽細胞への移行とアポトーシス抵抗性を媒介します   



[HTML] A computational approach for the identification of key genes and biological pathways of chronic lung diseases: a systems biology approach

H Rezaeeyan, NM Gh, B Fatemeh, M Arabfard - BMC Medical Genomics, 2023

… , idiopathic pulmonary fibrosis (IPF), … pulmonary fibrosis due to MUC5B expression. Furthermore, TGF-β has been shown to inhibit C3 by inhibiting CD46 and CD55. Therefore, TGF-β, despite causing pulmonary fibrosis in IPF, can prevent …

  • 慢性肺疾患の重要な遺伝子と生物学的経路を同定するための計算的アプローチ: システム生物学的アプローチ   



Ixekizumab-induced Interstitial Lung Disease

A Ahmed, P Khanna, O Al Omari, C Jani, D Patel… - American Journal of Therapeutics

… exposures, connective tissue diseases, and idiopathic causes, can cause them. The overall … pneumonitis, whereas the rest are classified as idiopathic ILD. Drug-induced ILD (DIILD) … opacities with bronchiectasis were consistent with pulmonary fibrosis (Figure …

  • イクセキズマブ誘発性間質性肺疾患   


 

 

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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。

当面、毎週アラートの内容をアップしていこうと思います。

 

癒しの音楽をお届けいたします。 

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