ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です！と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この１年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。
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24/06/15
[HTML] Clinical, radiological and histopathological features of patients with familial pulmonary fibrosis
H Jaula, L Mattila, E Lappi-Blanco, J Salonen… - Respiratory Research, 2024
… According to the 2022 guidelines for idiopathic pulmonary fibrosis (IPF), the patients were categorized as UIP (31/45.6%), probable UIP (20/… relatives are affected in familial pulmonary fibrosis (FPF) [1, 2]. FPF is a strong risk factor for …
- 家族性肺線維症患者の臨床的、放射線学的および組織病理学的特徴
[PDF] Changes in T‐cell subsets occur in interstitial lung disease and may contribute to pathology via complicated immune cascade
MA Karaselek, T Duran, S Kuccukturk, H Vatansev… - APMIS
… Twenty ILDs patients were included in the study, comprising those with idiopathicpulmonary fibrosis (IPF) (n:8), autoimmune-related ILDs (auto-… differences among the ILDs groups [idiopathic (IPF), autoimmune-related (auto-ILD), and orphan …
- 間質性肺疾患ではT細胞サブセットの変化が起こり、複雑な免疫カスケードを介して病理に寄与する可能性がある。
[HTML] Design, Synthesis, and Evaluation of a New Chemotype Fluorescent Ligand for the P2Y2 Receptor
R Knight, LE Kilpatrick, SJ Hill, MJ Stocks - ACS Medicinal Chemistry Letters, 2024
… The P2Y 2 receptor (P2Y 2 R) is a target for diseases including cancer, idiopathicpulmonary fibrosis, and atherosclerosis. However, there are insufficient P2Y 2 R antagonists available for validating P2Y 2 R function and future drug development …
- P2Y2受容体に対する新しい化学型蛍光リガンドの設計、合成、評価
24/06/14
Causal effect of immune cells on idiopathic pulmonary fibrosis: A mendelian randomization study
X Li, B Zhou, F Xu, H Liu, X Jia - Heart & Lung, 2024
… idiopathic pulmonary fibrosis (IPF) is the involvement of immune cells. However, the causal interaction between different immune cell signatures and IPF … T cells showed a protective effect against IPF, providing effective insights for preventing and …
- 特発性肺線維症に対する免疫細胞の因果効果：メンデルランダム化研究
[PDF] POS0556 DNA METHYLATION ESTIMATES OF HYPER-AGING IN SYSTEMIC SCLEROSIS AND IDIOPATHIC PULMONARY FIBROSIS
K Keen, B Zhuang, M Fritzler, C Ryerson, P Wilcox… - 2024
… idiopathic pulmonary fibrosis (IPF) are both considered to be diseases of early aging. As well, disorders of epigenetic processes are implicated in SSc-ILD, which is predominantly female, and IPF… sclerosis, ILD for interstitial lung disease, and IPF …
- POS0556 全身性硬化症および特発性肺線維症におけるDNAメチル化による超老化の推定
99mTc-3PRGD2 SPECT/CT imaging for the Diagnosis and Monitoring of Pulmonary Fibrosis: A Feasibility Study
X Zhao, H Gao, Y Sun, Y Yu, Q Luo, L Xu, G Yang… - 2024
… Introduction: Idiopathic pulmonary fibrosis(IPF) is a chronic and progressive lung disease with a high mortality rate. The current diagnostic … of pulmonary fibrosis. Methods: The preclinical study evaluated the increased expression of integrin β 3 in …
- 肺線維症の診断とモニタリングのための 99mTc-3PRGD2 SPECT/CT イメージング: 実現可能性研究
[HTML] Pulmonary fibroblast-specific delivery of siRNA exploiting exosomes-based nanoscaffolds for IPF treatment
H Lu, X Liu, M Zhang, H Bera, W Xu, H Jiang, X Zhao… - Asian Journal of …, 2024
… Idiopathic pulmonary fibrosis (IPF) is a progressive pulmonary disease that leads to … involved in the progression and exacerbation of IPF. It mediates nuclear transfer of Smad2/… might be a promising therapeutic strategy for IPF. Herein, we …
- IPF治療のためのエクソソームベースのナノスキャフォールドを利用した肺線維芽細胞特異的siRNA送達
Autotaxin-Specific PET/CT Imaging in a Preclinical Model of Pulmonary Fibrosis
X Deng, J Liu, J Zhou, Y Shi, J Chen, B Yu, S Liang… - 2024
… Introduction: Idiopathic pulmonary fibrosis(IPF) is a fatal disease with unpredictable progression and limited therapeutic … of IPFprogression. The enzyme Autotaxin (ATX) emerges as a prominently expressed extracellular …
- 肺線維症の前臨床モデルにおけるオートタキシン特異的 PET/CT 画像
Comparative Analysis of FDG and FAPI PET/CT Imaging in Interstitial Lung Disease: Focused on Progressive Pulmonary Fibrosis Prediction
Q Fang, R Zhao, J Cui, Q Han, Y Li, P Hou, S Liu, M Ke… - 2024
… Except for idiopathic pulmonary fibrosis(IPF), some ILDs, despite regular treatment, manifest progressive pulmonary fibrosis (PPF), leading to heightened mortality. Early diagnosis of PPF is pivotal for prognosis; however, conventional …
- 間質性肺疾患におけるFDGとFAPI PET/CT画像の比較分析：進行性肺線維症の予測に焦点を当てる
Hypermetabolic lung nodules in patients with fibrotic lung diseases
G Khawaja, N Emamifar, SP Aciu, M Kumaran… - 2024
… : idiopathic pulmonary fibrosis, sarcoidosis, asbestosis, and unspecified interstitial lung disease. 28 patients were categorized in sarcoidosis, 10 patients in idiopathicpulmonary fibrosis, … sarcoidosis patients, 6 out of 10 idiopathic pulmonary fibrosis …
- 線維性肺疾患患者における代謝亢進性肺結節
[PDF] AB0383 IL11, A GENETIC BIOMARKER FOR THE ACCURATE DIAGNOSIS OF INTERSTITIAL LUNG DISEASE ASSOCIATED WITH AUTOIMMUNE DISEASES
V Pulito-Cueto, DI Fernández, VM Mora-Cuesta… - 2024
… partially to the similarity with other diseases such as idiopathic pulmonary fibrosis (IPF) and interstitial pneumonia with autoimmune features (… stimulates their excessive collagen deposition in tissues, is linked to the pathogenesis of IPF, the …
- AB0383 IL11、自己免疫疾患に関連する間質性肺疾患の正確な診断のための遺伝子バイオマーカー
24/06/12
[PDF] A targeted literature review of lung function decline in idiopathic pulmonary fibrosis to improve survival predictions in cost-effectiveness analyses
OM Dong, WL Herring, P Chopra, B Elpers…
… a Suspected acute exacerbation was defined in the study by an idiopathic acute respiratory … , or hospitalizations to determine whether they were related to an IPF acute exacerbation. … to review the IPF disease progression literature for …
- 特発性肺線維症における肺機能低下に関する文献レビューをターゲットとし、費用対効果分析における生存予測の改善を図る
[HTML] Idiopathic Pulmonary Fibrosis.
A Sankari, K Chapman, S Ullah
… Idiopathic pulmonary fibrosis (IPF) is a progressive lung disorder characterized by scarring of the lungs from an unknown cause. The condition has a poor long-term prognosis. Classic features of IPF include the gradual onset of shortness of breath …
- 特発性肺線維症
24/06/10
[PDF] Multiplexed and volumetric imaging of human organs to characterize capillary cell plasticity in lung injury and fibrogenesis
L Yang, H Munich
… One of the archetypal examples of an organ fibrosis is the lethal disease IdiopathicPulmonary Fibrosis (IPF… pulmonary fibrosisin IPF patients. For instance, recent single-cell transcriptomic analysis has revealed the appearance of similar …
- 肺損傷および線維形成における毛細血管細胞の可塑性を特徴付けるためのヒト臓器の多重化および体積画像化
24/06/09
Fibroblast growth factor 21 alleviates idiopathic pulmonary fibrosis by inhibiting PI3K-AKT-mTOR signaling and stimulating autophagy
J Qi, Y Wu, Z Guo, S Zhu, J Xiong, F Hu, X Liang, X Ye - International Journal of …, 2024
… Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive pulmonary disease with an unclear … Here, we have demonstrated that fibroblast growth factor 21 (FGF21) ameliorates IPF via the … We conclude that FGF21 ameliorates IPF by inhibiting the …
- 線維芽細胞増殖因子21はPI3K-AKT-mTORシグナル伝達を阻害し、オートファジーを刺激することで特発性肺線維症を軽減する
Fibrin-PET Imaging Reveals Ongoing Lung Injury in Idiopathic Pulmonary Fibrosis
JK Munchel, AK Misra, SA Collins, R DiGregorio… - American Journal of …, 2024
… Idiopathic pulmonary fibrosis (IPF) is thought to represent the culmination of aberrant wound healing responses to repetitive lung injury1-2… established in IPF. We hypothesized that lung fibrin deposition, as a marker of ongoing lung injury …
- フィブリンPET画像により特発性肺線維症における進行中の肺損傷が明らかに
[PDF] Potential natural hydrosol blend TGLON suppresses the proliferation of five cancer cell lines and also ameliorates idiopathic pulmonary fibrosis in mouse model
WH Huang, ML Chang, CC Lin, CP Wang, FJ Tsai… - 2024
Background: Previous studies on natural substances for tumor cell inhibition have predominantly concentrated on efficacy, often overlooking safety concerns. This research utilizes" The Greatest Love of Nature (TGLON), a proprietary blend of plant …
Outcomes of idiopathic pulmonary fibrosis patients with high body mass index undergoing extracorporeal membrane oxygenation support
J Tian, Y Dong, T Zhou, J Zhang, H Xu - Zhonghua wei zhong bing ji jiu yi xue, 2024
[Outcomes of idiopathic pulmonary fibrosispatients with high body mass index undergoing extracorporeal membrane oxygenation support] [Outcomes of idiopathic pulmonary fibrosispatients with high body mass index undergoing extracorporeal …
Lung Fibrosis Is Linked to Increased Endothelial Cell Activation and Dysfunctional Vascular Barrier Integrity
E Fließer, K Jandl, T Lins, A Birnhuber, F Valzano… - American Journal of …, 2024
… What have we learned from basic science studies on idiopathic pulmonary fibrosis? Eur Respir Rev 2019: 28(153). 5. … Increased level of soluble E-selectin in the serum from patients with idiopathic pulmonary fibrosis. Inflammation 2004: 28(1): 1-5. 27. …
- 肺線維症は内皮細胞の活性化の増加と血管バリアの機能不全に関連している
Pirfenidone improves voiding function by suppressing bladder fibrosis in underactive bladder rats
IG Ko, L Hwang, JJ Jin, SH Kim, CJ Kim, YH Choi… - European Journal of …, 2024
… Pirfenidone is a powerful anti-fibrotic agent that inhibits the progression of fibrosis in people with idiopathic pulmonary fibrosis. In the current study, we evaluated the efficacy of pirfenidone in the treatment of bladder fibrosis in a UAB rat model. UAB …
- ピルフェニドンは低活動膀胱ラットの膀胱線維症を抑制することで排尿機能を改善する
[HTML] The Role of Eosinophilic Inflammation in Inflammatory Bowel Diseases: Conductor or “First” Violin?
GH Babayeva, HI Ibrahimli, FV Guliyev, GV Asadova… - 2024
… This cytokine promotes pulmonary fibrosis, and an increase in IL-4 and IL-13 receptors on lung fibroblasts was observed in patients with idiopathic pulmonary fibrosis [60]. IL-13 is also involved in intestinal fibrosis. Fibrosis in mice chronically …
- 炎症性腸疾患における好酸球性炎症の役割：指揮者か「第一」バイオリンか？
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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
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