AIとIPFと癒しの音楽

特発性肺線維症 idiopathic pulmonary fibrosis (IPF)患者によるIPF関連学術情報の収集とシェア。癒しの音楽もお届けしています。

IPF Weekly Update

ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です！と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この１年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。

<><><>

23/10/14

 

[HTML] Polymyxin B-immobilised fibre column treatment for acute exacerbation of idiopathic pulmonary fibrosis patients with mechanical ventilation: a nationwide …

N Awano, T Jo, T Izumo, M Inomata, Y Ito, K Morita… - Journal of Intensive Care, 2023

… IPF were selected as follows. Firstly, we excluded patients with any of the following diagnoses of idiopathic interstitial pneumonias other than IPF recorded in Japanese text: idiopathic … , idiopathic pleuroparenchymal fibroelastosis and …

  • 人工呼吸器を使用している特発性肺線維症患者の急性増悪に対するポリミキシン B 固定化ファイバーカラム治療：全国的な観察研究



[PDF] 4.16 Perfenidone vs Nintedanib for Idiopathic Pulmonary Fibrosis-an Observational study at a Teaching Hospital in Republic of Ireland.

JR Awan, O Shinners, S Shahsavari, O Rahman…

… idiopathic pulmonary fibrosis (IPF) treatments1. In this study we compared the two anti-fibrotic treatment regimens available for the treatment of idiopathic … Pirfenidone vs nintedanib for treatment of idiopathicpulmonary fibrosis in clinical …

  • 特発性肺線維症に対するピルフェニドンとニンテダニブの比較 - アイルランド共和国の教育病院での観察研究。



Genistein alleviates pulmonary fibrosis by inactivating lung fibroblasts

SH Kwon, H Chung, JW Seo, HS Kim - BMB reports

… Pulmonary fibrosis is a serious lung disease that occurs predominantly in men. Genistein is … However, the antifibrotic effects of genistein on pulmonary fibrosis are largely unknown. The … and primary fibroblasts from patients with idiopathic …

  • ゲニステインは肺線維芽細胞を不活化することで肺線維症を軽減



[HTML] Untargeted Metabolomics Reveals Alterations of Rhythmic Pulmonary Metabolism in IPF

W Sun, J Ren, Z Jia, P Liang, S Li, M Song, Y Cao… - Metabolites, 2023

… Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive condition characterized by the impairment of alveolar epithelial cells. Despite continued research efforts, the effective therapeutic medication is still absent due to an …

  • 非標的メタボロミクスにより、IPF における律動的な肺代謝の変化が明らかに



[PDF] Surgical Treatment of Secondary Pneumothorax-Complicated Interstitial Lung Disease

R Yoshino, N Yoshida, N Ujiie, A Ito, M Nakatsubo… - Cureus, 2023

… -induced, three cases of idiopathicpulmonary fibrosis (IPF)/cryptogenic fibrosing alveolitis, … or associations such as drugs or occupational ILD, idiopathic ILDs (IILDs), connective tissue … ILDs with fibrosis, such as idiopathic pulmonary fibrosis (IPF) …

  • 続発性気胸合併間質性肺疾患の外科的治療



Preliminary Findings of an Adapted Nurse-Led Palliative Care Intervention

D Layne, N Milano, T Kelechi, M Madsetti, K Lindell - Journal of Palliative Medicine, 2023

… care intervention for people with idiopathicpulmonary fibrosis and caregivers (A Program of … in caregivers of patients with idiopathicpulmonary fibrosis. Ann Am Thorac Soc 2021;18(11):… (SUPPORT) for patients with idiopathic pulmonary …

  • 適応した看護師主導の緩和ケア介入の予備的所見





23/10/12

 

[HTML] 99mTc-Labeled FAPI SPECT Imaging in Idiopathic Pulmonary Fibrosis: Preliminary Results

Y Liu, Q Zhang, Y Zhang, J Wang, Y Wu, G Yang, J Shi… - Pharmaceuticals, 2023

Aim: Idiopathic pulmonary fibrosis (IPF) is associated with a poor prognosis, presenting the most aggressive form of interstitial lung diseases (ILDs). Activated fibroblasts are crucial for pathological processes. Fibroblast activation protein (FAP) …

  • 特発性肺線維症における 99mTc 標識 FAPI SPECT イメージング: 暫定結果



[PDF] Bioinformatics approach to identify the hub gene associated with COVID‐19 and idiopathic pulmonary fibrosis

W Shi, T Li, H Li, J Ren, M Lv, Q Wang, Y He, Y Yu… - IET Systems Biology, 2023

… on the mechanisms by which COVID‐19 and IPF act concertedly. In the field of … IPF patients by transcriptomic analysis of severe SARS‐CoV‐2 infection and IPF patients. Hub genes were identified to discover the molecular mechanisms in …



Transcriptome Sequencing of lncRNAs, circRNAs, miRNAs, mRNAs, and Interaction Network Constructing in Acute Exacerbation of Idiopathic Pulmonary Fibrosis.

N Zang, J Wang, T Li, P Li, Y Liu, J Pan, L Pang, X Lv - Discovery Medicine, 2023

… Five IPF patients with LHCS and five IPFpatients with LDCS were recruited in this study to perform RNA sequencing and miRNA sequencing. Further analysis was carried out on the differential expression profiles of lncRNAs, circRNAs, miRNAs …

  • 特発性肺線維症の急性増悪における lncRNA、circRNA、miRNA、mRNA および相互作用ネットワークのトランスクリプトーム配列決定。



Real World Experience on the Effectiveness and Safety of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis in Taiwan

CY Chang, YF Wei, CY Chen, YC Lai, PW Hu, JC Hung… - Frontiers in Medicine

… a reduced risk of acute exacerbation in patients with idiopathic pulmonary fibrosistreated with the antifibrotic prifenidone. The present study … IPF in Taiwan. Methods: Between January 1, 2019 and December 31, 2020, we enrolled 50 patients who …

  • 台湾の特発性肺線維症患者におけるピルフェニドンの有効性と安全性に関する実際の経験



L Zeng, Y Tang, Y Zhang, L Yue, G Ma, X Ye, L Yang… - Frontiers in Immunology

… Idiopathic pulmonary fibrosis (IPF) belongs to the broader spectrum of ILD and evidence shows that common pathologic pathways might lie between IPF and DM-ILD.We retrieved gene expression profiles of DM and IPF from the Gene Expression …



Up-regulation by overexpression of c-MET in fibroblastic foci of usual interstitial pneumonia.

L Melocchi, G Cervi, G Sartori, L Gandolfi, G Jocollé… - Pathologica, 2023

… Usual interstitial pneumonia (UIP) is the radiologic and histologic hallmark of idiopathicpulmonary fibrosis (IPF) and the commonest … ) is one of the main molecular pathways recently identified by transcriptomic studies in IPF. Fibroblastic …

  • 通常の間質性肺炎の線維芽細胞病巣におけるc-METの過剰発現による上方制御。



Evaluation of multiple immunoassay formats for detection of anti-drug antibodies to zinpentraxin alfa

X Yang, K Siradze, G Sperinde, A Arjomandi, S Fischer - Journal of Immunological …, 2023

… Zinpentraxin alfa (rhPTX-2; PRM-151) is currently being developed for the treatment of fibrotic diseases such as idiopathic pulmonaryfibrosis and myelofibrosis. Notably, because it is administered chronically and has an endogenously expressed …

  • ジンペントラキシン アルファに対する抗薬物抗体を検出するための複数のイムノアッセイ形式の評価



Granger Causality and Information Transfer in Physiological Systems: Basic Research and Applications

S Charleston-Villalobos, M Javorka, L Faes, A Voss - Frontiers in Network Physiology

… analyses on cardiorespiratory signals obtained from patients with idiopathic pulmonaryfibrosis (IPF) before and during oxygen supplementation to characterize cardiovascular control and cardiorespiratory interactions [15]. In IPF patients, a shift …

  • 生理システムにおけるグレンジャーの因果関係と情報伝達: 基礎研究と応用



23/10/10

 

An up-to-date review of approved and emerging antibody therapies for idiopathic pulmonary fibrosis

J Simonetti, G Sgalla, L Richeldi - Expert Opinion on Biological Therapy, 2023

… in treating Idiopathic Pulmonary Fibrosis(IPF) has shown significant slowing down of the progressive functional decline in these patients. In recent times, antibody-based therapies with precise molecular targets have also been explored as alternative …

  • 特発性肺線維症に対する承認済みおよび新興の抗体療法に関する最新のレビュー



[HTML] Dietary intake and incidence risk of idiopathic pulmonary fibrosis: a Mendelian randomization study

Y Zhang, Y Gan, H Zhang - BMC Pulmonary Medicine, 2023

… However, the causal relationship between dietary intake and idiopathic pulmonaryfibrosis (IPF) remains unclear… Idiopathicpulmonary fibrosis (IPF) is a chronic progressive interstitial lung disease of unknown etiology. In Europe, there …

  • 食事摂取量と特発性肺線維症の発生リスク：メンデルランダム化研究



Fraxetin alleviates BLM-induced idiopathic pulmonary fibrosis by inhibiting NCOA4-mediated epithelial cell ferroptosis

X Zhai, J Zhu, J Li, Z Wang, G Zhang, Y Nie - Inflammation Research, 2023

… Idiopathic pulmonary fibrosis (IPF) is a debilitating lung condition with few available treatments. The early driver of wound repair that contributes to IPF has been extensively identified as repetitive alveolar epithelial damage. According to …

  • フラキセチンはNCOA4媒介上皮細胞のフェロトーシスを阻害することにより、BLM誘発性の特発性肺線維症を軽減



Non-peptidic immunoproteasome β5i-Selective inhibitor as potential treatment for idiopathic pulmonary fibrosis: Virtual screening, hit evolution and lead identification

Y Li, G Nan, X Hou, Y Yan, Y Yang, Y Yang, K Li… - European Journal of …, 2023

… for idiopathic pulmonary fibrosis (IPF). We report herein our efforts to discover novel non-peptidic immunoproteasome inhibitors as potential treatment for IPF. … Notably, when administered at 30 mg/kg in a bleomycin-induced IPF mouse model …

  • 特発性肺線維症の潜在的な治療法としての非ペプチド性免疫プロテアソーム β5i 選択的阻害剤: バーチャル スクリーニング、ヒット進化およびリード同定



DEUPIRFENIDONE (LYT-100) DOSE-SELECTION RATIONALE FOR A PHASE 2B IDIOPATHIC PULMONARY FIBROSIS (IPF) STUDY-ELEVATE

TM MAHER, MC CHEN, C KORTH, E ELENKO… - CHEST, 2023

PURPOSE: Pirfenidone (PIRF) is an approved antifibrotic that slows progression of lung function decline in IPF and in a real-world study improved 3-year survival. Current antifibrotics are poorly tolerated, leading to suboptimal dosing or …

  • 第 2B 相特発性肺線維症 (IPF) 研究におけるデュピルフェニドン (LYT-100) の用量選択理論的根拠



EFFICACY OF COMPREHENSIVE TELE-HEALTH REHABILITATION PROGRAM IN IDIOPATHIC PULMONARY FIBROSIS

R BANSAL, K BLIDEN, A GARG, S SINGH, P KUNDAN… - CHEST, 2023

… of TPR in the Idiopathic Pulmonary Fibrosis(IPF) population is uncertain. This study assesses the efficacy of TPR in patients with IPF. We … METHODS: A prospective observational study was conducted in stable IPFpatients meeting ATS/ERS …



A MISFIRED WEAPON: A RARE CASE OF IDIOPATHIC PULMONARY FIBROSIS ASSOCIATED WITH AGENT ORANGE EXPOSURE IN A VIETNAM VETERAN

A PURI, C LAU, S IUSIM - CHEST, 2023

… Here we present a rare case of idiopathicpulmonary fibrosis (IPF) associated with Agent Orange exposure in a Vietnam War veteran. … of usual interstitial pneumonia (UIP) pattern/idiopathic pulmonary fibrosis. DISCUSSION: IPF associated with Agent …



DETERMINANTS OF PULMONARY HYPERTENSION GROUP 3 IN IDIOPATHIC PULMONARY FIBROSIS

K EL GHARIB, R GROVU, F SAKR, S ASMAR… - CHEST, 2023

… We included patients between the ages of 18 and 90, diagnosed with Idiopathic PulmonaryFibrosis … RESULTS: A total of 12221 patients with IPF were included in the study, of which 3001 … not however correlate with the development of …

  • 特発性肺線維症における肺高血圧症グループ 3 の決定因子



A CASE REPORT OF SEVERE PULMONARY HYPERTENSION DUE TO IDIOPATHIC PULMONARY FIBROSIS

P CHOW, B VEFALI, W AIMAN, HOM SHARMA… - CHEST, 2023

… Idiopathic pulmonary fibrosis, a highly morbid and progressive disease, further complicates treatment. CASE PRESENTATION: A 79-year-old female with severe right and left heart failure due to idiopathic pulmonaryfibrosis (IPF), … comorbidities …

  • 特発性肺線維症による重度肺高血圧症の症例報告



 

 

<><><>

 

特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。

当面、毎週アラートの内容をアップしていこうと思います。

 

癒しの音楽をお届けいたします。 

youtu.be

###