AIとIPFと癒しの音楽

特発性肺線維症 idiopathic pulmonary fibrosis (IPF)患者によるIPF関連学術情報の収集とシェア。癒しの音楽もお届けしています。

IPF Weekly Update

ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です!と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この1年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。

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23/08/05

 

The effect of CALIPER-derived parameters for idiopathic pulmonary fibrosis in predicting prognosis, progression, and mortality: a systematic review

X Jiao, H Song, W Liu, J Yang, Z Wang, D Yang… - European Radiology, 2023

idiopathic pulmonary fibrosis (IPF), is characterized by subjective variability among radiologists and insensitivity to subtle changes. Recently, a few studies have aimed to decrease subjective bias by assessing the severity of IPF… the effect of …

  • 予後、進行、死亡率の予測における特発性肺線維症のCALIPER由来パラメータの効果:系統的レビュー   



[HTML] Idiopathic pulmonary fibrosis in the United States: time to diagnosis and treatment

MB Herberts, TT Teague, V Thao, LR Sangaralingham… - BMC Pulmonary Medicine, 2023

… A total of 44,891 with IPF were identified. The most common diagnoses prior to diagnosis of IPF were upper respiratory infections (47%), acute bronchitis … Our retrospective cohort demonstrates that IPF is often diagnosed late, usually preceded …

  • 米国の特発性肺線維症:診断と治療にかかる時間   



[HTML] Acute exacerbation of idiopathic pulmonary fibrosis model in the rats using bleomycin and lipopolysaccharides

SV Kurniawan, M Louisa, J Zaini, S Surini, V Soetikno… - Journal of Advanced …, 2023

… a rat model of acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) using the combination of bleomycin … Idiopathicpulmonary fibrosis (IPF) is a chronic and progressive disease of unknown etiology of the respiratory system that is limited to …

  • ブレオマイシンとリポ多糖を用いたラットにおける特発性肺線維症の急性増悪モデル   



Genetic Association of Circulating Adipokines with Risk of Idiopathic Pulmonary Fibrosis: A Two-Sample Mendelian Randomization Study

D Huang, L Gong, Z Wu, Y Shi, Z Liang - Lung, 2023

idiopathic pulmonary fibrosis (IPF) are yet to be established. We performed a two-sample Mendelian randomization (MR) study to investigate the causal roles of adipokines on IPF… It remains unclear whether aberrant adipokines cause IPF or IPF

  • 循環アディポカインと特発性肺線維症のリスクとの遺伝的関連:2サンプルのメンデルランダム化研究   



Progress in Understanding and Treating Idiopathic Pulmonary Fibrosis: Recent Insights and Emerging Therapies

H Guo, J Sun, S Zhang, Y Nie, S Zhou, Y Zeng - Frontiers in Pharmacology

… exacerbations among IPF patients. Nonetheless, these pharmacological interventions do not present a definitive solution to IPF, … This comprehensive review encapsulates the recent advancements in IPFresearch, spanning from …

  • 特発性肺線維症の理解と治療の進歩:最近の洞察と新しい治療法   



[PDF] Economic Burden of Idiopathic Pulmonary Fibrosis in Spain: A Prospective Real-World Data Study (OASIS Study)

RN MARIA JESUS, E Cano‑Jiménez, AD Romero Ortiz… - 2023

… Background Idiopathic pulmonary fibrosis(IPF) is a progressive and fatal lung disease … of IPF according to forced vital capacity (FVC) % predicted level in adult patients. Methods We conducted a prospective, observational, multicentric study of …

  • スペインにおける特発性肺線維症の経済的負担:前向きな実世界データ研究(OASIS研究)   



Variations in S100A8/A12 Gene Expression Are Associated with the Efficacy of Nintedanib and Acute Exacerbation Development in Idiopathic Pulmonary Fibrosis

N Arai, M Nakajima, M Matsuyama, S Matsumura… - American Journal of …, 2023

… with idiopathic pulmonary fibrosis (IPF). In INPULSIS-2 (Safety and Efficacy of BIBF 1120 at High Dose in Idiopathic Pulmonary Fibrosis … nintedanib and the development of acute exacerbations in patients with idiopathicpulmonary fibrosis. (A) …

  • S100A8/A12遺伝子発現の変動は、ニンテダニブの有効性と特発性肺線維症患者の急性増悪の発症に関連している   



Integration and application of radiologic patterns from clinical practice guidelines on idiopathic pulmonary fibrosis and fibrotic hypersensitivity pneumonitis

DC Marinescu, CJ Hague, NL Muller, D Murphy… - CHEST, 2023

… was idiopathic pulmonary fibrosis (IPF) in 26%, fHP in 12%, connective tissue disease-associated ILD (CTD-ILD) in 34%, idiopathicpneumonia with … Typical and probable UIP patterns corresponded to a diagnosis of IPF in 66 and 57% of …

  • 特発性肺線維症および線維性過敏性肺炎に関する診療ガイドライン放射線パターンの統合と適用   



Improving Idiopathic Pulmonary Fibrosis Damage Prediction with Segmented Images in a Deep Learning Model

S Leyva-López, G Hernández-Nava, E Mena-Camilo… - 2023 IEEE Conference on …, 2023

This work introduces a semantic segmentation model, UNet, as a preprocessing module to an algorithm predicting lung damage caused by Idiopathic Pulmonary Fibrosis. By modifying the model input through the incorporation of a guide image (a …

  • 深層学習モデルのセグメント化画像による特発性肺線維症の損傷予測の改善   



Maximal respiratory pressures: Measurements at functional residual capacity in individuals with different health conditions using a digital manometer

BMF Silveira, HR Martins, GA Ribeiro-Samora… - Brazilian Journal of Physical …, 2023

idiopathic pulmonary fibrosis (IPF), with chronic heart failure (CHF), as well as individuals affected by stroke and, ii) to compare the mean differences between the measurements at FRC and at RV /TLC among the five groups. We hypothesized that …

  • 最大呼吸圧:デジタル圧力計を使用して、さまざまな健康状態を持つ個人の機能的残気量を測定する 




23/08/03

 

F Yang, Wendusubilige, J Kong, Y Zong, M Wang… - EPMA Journal, 2023

Idiopathic pulmonary fibrosis (IPF) is a rare interstitial lung disease with a poor prognosis that currently lacks effective treatment methods. … den Lungen-6, can diagnose IPF but do not distinguish the degree of pulmonary fibrosis[11]. More …

  • 統合オミクスアプローチと機械学習戦略を使用して、予測、予防、個別化医療の文脈における特発性肺線維症における酸化ストレス関連バイオマーカーの同定   



A role for the terminal C5-C9 complement pathway in idiopathic pulmonary fibrosis

LIB Sikkeland, T Ueland, MB Lund, MT Durheim… - Frontiers in Medicine

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial lung disease characterized by damage to the alveolar epithelium, … lavage (BAL) from IPF patients and controls, and found that the complement pathway was highly …

  • 特発性肺線維症における末端C5-C9補体経路の役割   



[HTML] Idiopathic bronchiolocentric interstitial pneumonia: A rare presentation

R Chetambath, R Shanavas, M Krishnaprasad… - Journal of Advanced Lung …, 2023

… It is considered an aggressive disease with a prognosis somewhere between idiopathicpulmonary fibrosis and NSIP. Here, we report a case of idiopathic bronchiolocentric interstitial pneumonia, which was initially suspected as chronic …



[HTML] The deubiquitinase UCHL3 mediates p300-dependent chemokine signaling in alveolar type II cells to promote pulmonary fibrosis

SY Lee, SY Park, SH Lee, H Kim, JH Kwon, JY Yoo… - Experimental & Molecular …, 2023

Idiopathic pulmonary fibrosis (IPF), one of the most common manifestations of idiopathicinterstitial pneumonia, is a chronic, fatal, fibrotic, interstitial lung disease of unknown cause 1 . Many studies have attempted to elucidate the molecular mechanisms …

  • 脱ユビキチン化酵素UCHL3は、肺胞II型細胞のp300依存性ケモカインシグナル伝達を媒介して肺線維症を促進する   



Time course of histopathology of bleomycin-induced pulmonary fibrosis using an intratracheal sprayer in mice

K Hideyuki, T Ayami, H Sumihiko - 実験動物彙報, 2023

… <p>Idiopathic pulmonary fibrosis (IPF) is a poor prognosis disease that affects approximately 5 million people worldwide, and the detailed … of IPF remain unclear. Bleomycin-induced pulmonary fibrosis has been widely used as a representative …

  • マウスの気管内噴霧器を用いたブレオマイシン誘発肺線維症の病理組織学的経時変化   



Investigating the Use of Translational Methods to Characterize Therapeutic Interventions in Models of Pulmonary Disease

AR Chang - 2023

Idiopathic Pulmonary Fibrosis (IPF) is an interstitial lung disease with no known cause or cure. IPF has an incidence of 75/1,000,000 of the … Our use of translatable methodologies in the bleomycin mouse model of IPF led to the novel identification of …

  • 肺疾患モデルにおける治療介入を特徴付けるトランスレーショナル技術の使用の研究   



[HTML] ER Stress Receptor

X Chen, M Li, M Li, D Wang, J Zhang

… Nintedanib (BIBF1120), a triple angiokinase inhibitor, was first approved for idiopathicpulmonary fibrosis (IPF) therapy and is also … Unlike most VEGFR, PDGFR and FGFR inhibitors, nintedanib was first approved by the FDA for idiopathic

  • ERストレス受容体  




Mass cytometry analysis of B-cell populations in extranodal marginal-zone lymphoma of mucosa-associated lymphoid tissue of the lung

T Yanagihara, K Hata, K Matsubara, K Kunimura… - Annals of Hematology, 2023

… The mass cytometry analysis of BALF cells from the patient revealed distinctive patterns of B-cell populations in comparison to other lung diseases, such as idiopathic pulmonaryfibrosis (IPF), connective tissue disease-related interstitial lung …

  • 肺の粘膜関連リンパ組織の節外辺縁帯リンパ腫におけるB細胞集団のマスサイトメトリー分析   



Novel opportunities from bioimaging to understand the trafficking and maturation of intracellular pulmonary surfactant and its role in lung diseases

MJ Garcia, L Amarelle, L Malacrida, A Briva - Frontiers in Immunology

… Furthermore, PS alterations play a significant role in chronic lung diseases such as chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF). The intracellular stage involves storing and releasing a specialized subcellular …

  • 細胞内肺サーファクタントの輸送と成熟、および肺疾患におけるその役割を理解するためのバイオイメージングからの新たな機会   



23/08/01

 

Imaging Features of Idiopathic Interstitial Lung Diseases

K Batra, TN Adams - Journal of Thoracic Imaging, 2023

… The 2013 American Thoracic Society (ATS)/European Respiratory Society (ERS) guidelines are the most widely accepted classification of IIPs and include the following diagnoses: idiopathic pulmonary fibrosis(IPF), idiopathic nonspecific …

  • 特発性間質性肺疾患の画像上の特徴   



[PDF] The Added Power of Synthetic Control Groups: Challenging Conventional Wisdom and Trial Design in Idiopathic Pulmonary Fibrosis Research

TM Dempsey, AH Limper - American Journal of Respiratory and Critical Care …, 2023

… disease like idiopathic pulmonary fibrosis(IPF), which is in part why the antifibrotic drugs pirfenidone and nintedanib remain the only two approved medications for use in patients with IPF.While the data for the effectiveness of the …

  • 合成対照群のさらなる力:特発性肺線維症研究における従来の知恵と試験デザインへの挑戦   



RNA binding proteins in Idiopathic Pulmonary Fibrosis

L Arnold - 2023

… For this, explanted lungs and interstitial fibroblasts isolated from IPF patients or healthy donors, mouse model of fibrosis as well as an in vitro … of RBPs and SG proteins in IPF. Our results also imply, that patient lungs and therapeutic targeting of …

  • 特発性肺線維症におけるRNA結合タンパク質   




[HTML] Concordance between transbronchial lung cryobiopsy and surgical lung biopsy for interstitial lung disease in the same patients

T Baba, T Takemura, K Okudela, A Hebisawa… - BMC Pulmonary Medicine, 2023

… Similar to SLB, TBLC increases diagnostic confidence in the multidisciplinary diagnosis of idiopathic pulmonary fibrosis (IPF) [7]. Recent IPF clinical practice guideline has conditionally recommended TBLC as an acceptable alternative to SLB

  • 同じ患者における間質性肺疾患に対する経気管支肺凍結生検と外科的肺生検との一致   




Dysregulated cross-talk between alveolar epithelial cells and stromal cells in IPF reduces epithelial regenerative capacity

M Wisman, M Nizamoglu, JA Noordhoek, W Timens… - Frontiers in Medicine

… In idiopathic pulmonary fibrosis (IPF) constant epithelial micro-injury and aberrant interactions within the stromal micro-environment lead to abnormal alveolar repair and fibrosis. We hypothesized that alveolar epithelial regenerative responses in IPF

  • IPFにおける肺胞上皮細胞と間質細胞間のクロストークの調節不全により、上皮の再生能力が低下する   



Interstitial Lung Disease and Sarcoidosis

M Sharp, AM Mustafa, N Farah, CA Bonham - Clinics in Chest Medicine, 2023

… of the lung interstitium, also termed pulmonary fibrosis. 1, 2 Causes of ILD vary from known etiologies, such as connective-tissue disease (CTDILD) and hypersensitivity pneumonitis (HP), to unknown etiologies such as idiopathic

  • 間質性肺疾患とサルコイドーシス  



[PDF] A Truck Driver With Progressive Dyspnea and Cough

AMA Hameed, AA Sayf, K Thavarajah, DR Ouellette - 2023

Background A 66-year-old man presents to his primary care physician with a 12-month history of progressive dyspnea and nonproductive cough. Six months earlier, his respiratory symptoms worsened after he had COVID-19; he received no treatment …

  • 進行性の呼吸困難と咳を伴うトラック運転手

 

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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。

当面、毎週アラートの内容をアップしていこうと思います。

 

癒しの音楽をお届けいたします。 

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