AIとIPFと癒しの音楽

特発性肺線維症 idiopathic pulmonary fibrosis (IPF)患者によるIPF関連学術情報の収集とシェア。癒しの音楽もお届けしています。

IPF Weekly Update

ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です!と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この1年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。



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24/05/02

 

Incidence, prevalence and mortality of idiopathic pulmonary fibrosis in England from 2008 to 2018: a cohort study

R Gupta, AD Morgan, PM George, JK Quint - Thorax, 2024

idiopathic pulmonary fibrosis (IPF) is diagnosed it is challenging to establish a consistent understanding of the disease burden In the UK, over 10 years ago, the incidence and prevalence of IPF … and prevalence of IPF in England from 2008 to …

  • 2008年から2018年までのイギリスにおける特発性肺線維症の発生率、有病率、死亡率:コホート研究 




Involvement of E3 ubiquitin ligase NEDD4-mediated YY1 ubiquitination in alleviating idiopathic pulmonary fibrosis

L Chen, Q Sun, R Yue, H Yan, X Huang, H Yu, Y Yang - International Journal of …, 2024

Idiopathic pulmonary fibrosis (IPF) is a chronic and lethal lung disease characterized by progressive lung … of IPF. Through bioinformatics analysis and both in vitro and in vivo experiments, we observed differential expression levels of …

  • 特発性肺線維症の緩和におけるE3ユビキチンリガーゼNEDD4媒介YY1ユビキチン化の関与




Epidemiology of idiopathic pulmonary fibrosis: opportunities and hurdles for population-level studies of rare disease

DC Marinescu, AW Wong - Thorax, 2024

Idiopathic pulmonary fibrosis Idiopathicpulmonary fibrosis (IPF) is a rare condition for which reliable disease trends over time can be difficult to obtain. Understanding the epidemiology of IPF is crucial given its impact on quality of life …

  • 特発性肺線維症の疫学: 希少疾患の集団レベルの研究の機会とハードル




[PDF] Aspergilloma Coexisting With Idiopathic Pulmonary Fibrosis: A Rare Clinical Entity

KK Athish, TJ Guruprasad, S Padmanabha… - Cureus, 2024

… Here, we have a rare case of idiopathicpulmonary fibrosis (IPF) with bilateral bronchiectasis complicated by aspergilloma. Although the … between aspergilloma and complex lung pathologies like IPF. The rare coexistence of aspergilloma with IPF

  • 特発性肺線維症と共存するアスペルギルス:まれな臨床実体




[HTML] Clinical behaviour and mortality in idiopathic vs secondary nonspecific interstitial pneumonia

T Wijayaratne, J Owen, A Fahim - Lung India, 2024

… Future research into the management strategies would be paramount for an evidence base management of this subtype of ILD on similar lines to IPF, as the fibrotic variant of NSIP can have a prognosis fairly similar to IPF [ 12 ] and it may be …

  • 特発性対二次性非特異的間質性肺炎における臨床行動と死亡率




[PDF] Exploring the Common Genetic Underpinnings of Chronic Pulmonary Disease and Esophageal Carcinoma Susceptibility

D Zhang, Y Zhou, T Lu, J Li, L Zhu, S Li, Y Li, X Duan - Journal of Cancer, 2024

… and asthma, COPD, and idiopathicpulmonary fibrosis leveraging extensive GWAS datasets. … COPD and asthma, but not idiopathic pulmonary fibrosis. Further analyses identified 13 … , while cancer liability reciprocally raised pulmonary

  • 慢性肺疾患と食道癌感受性の共通の遺伝的基盤を探る




Study of lung fibrogenesis induced by several noxae in vivo and in vitro models

C Goracci - 2024

idiopathic pulmonary fibrosis (IPF), are chronic and progressive disorders that severely affect the airways and other structures of the respiratory system. COPD and IPF… Pulmonary diseases, like chronic obstructive pulmonary disease (COPD) and …

  • いくつかの悪菌によって誘発される肺線維形成の in vivo および in vitro モデルの研究




Molecular Mechanisms and Roles of MiR-136-5p in Human Cancer and Other Disorders

X Chen, T Lu, Y Zheng, Z Lin, C Liu, D Yuan, C Yuan - Current medicinal chemistry

… MiR-136-5p represents a class of microRNAs (miRNAs) that are involved in various human maladies, encompassing cancers, cardio-cerebrovascular disease, diabetes, inflammatory disease, tuberous sclerosis, idiopathicpulmonary fibrosis

  • ヒトのがんおよびその他の疾患における MiR-136-5p の分子機構と役割




24/05/01

 

[HTML] Smoking status and clinical outcome in idiopathic pulmonary fibrosis: a nationwide study

HY Yoon, H Kim, Y Bae, JW Song - Respiratory Research, 2024

… Smoking status has been linked to the development of idiopathic pulmonary fibrosis(IPF). However, the effect of smoking on the prognosis of patients with IPF is unclear. We aimed to investigate the association between smoking status and all-cause …

  • 特発性肺線維症における喫煙状況と臨床転帰:全国的研究




How are the mechanisms that drive Idiopathic pulmonary fibrosis similar or different to other types of fibrosis

TM Sietsma - 2024

… It has been hard to diagnose people with IPFsince many of the symptoms of IPF are very similar … Among the other types of fibrosis that have similar pathologies with IPF they also tend to … Herein, I review the most important pathways and …

  • 特発性肺線維症を引き起こすメカニズムは他の種類の線維症とどのように似ているのか、それとも違うのか




Identification of CFH and FHL2 as biomarkers for idiopathic pulmonary fibrosis

X Liu, M Yang, J Li, H Liu, Y Dong, J Zheng, Y Huang - Frontiers in Medicine

… in the pathogenesis of IPF is significant, yet remains inadequately understood. This study aimed to identify potential key genes in IPF and their … In this study, CFH and FHL2 have been identified as novel potential biomarkers for IPF, with potential …

  • 特発性肺線維症のバイオマーカーとしてのCFHおよびFHL2の同定




[PDF] Mortality prediction in IPF: evaluation of automated CT analysis with conventional severity measures

B Bartholmai, M Srinivasan Kokosi

… Computer-based CT analysis can provide objective quantitation of disease in idiopathicpulmonary fibrosis (IPF). A computer algorithm, CALIPER, was compared with conventional CT and pulmonary function measures of disease severity for …

  • IPF における死亡率予測: 従来の重症度測定による自動 CT 解析の評価




[HTML] Aerosol delivery in interstitial lung diseases-breakthrough or lost cause?

C Ehrhardt - Expert Opinion on Drug Delivery, 2024

… Nintedanib is a kinase inhibitor, also inhibiting growth factors implicated in the pathogenesis of idiopathic pulmonary fibrosis (IPF), ie platelet-derived growth factor, vascular endothelial growth factor and fibroblast growth factor. Both drugs are given …

  • 間質性肺疾患におけるエアロゾル送達 - 画期的な治療法か、それとも失われた原因か?



24/04/30

 

Quantitative Analysis of Lung Shape in Idiopathic Pulmonary Fibrosis: Insights Into Disease-and Age-Associated Patterns

J John, AR Clark, H Kumar, KS Burrowes, AC Vandal… - Academic Radiology, 2024

… Fibrotic scarring in idiopathic pulmonaryfibrosis (IPF) typically develops first in the posterior-basal lung tissue before advancing to involve … understanding IPF risk and its staging. We hypothesized that lung and lobe shape in IPFwould have …

  • 特発性肺線維症における肺の形状の定量的分析: 疾患と年齢に関連するパターンについての洞察




24/04/29

 

Smoking and idiopathic pulmonary fibrosis: A meta-analysis

M Fang, B He, J Xiao - Nicotine and Tobacco Research, 2024

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibrotic interstitial lung disease that manifests as alveolar epithelial cell damage with abnormal repair mechanisms [1, 2]. IPF is one of the most severe and common idiopathicIPF

  • 喫煙と特発性肺線維症: メタ分析




[PDF] The Roles of Neuropeptide Y in Respiratory Disease Pathogenesis via the Airway Immune Response

J Itano, K Kiura, Y Maeda, N Miyahara - Acta Medica Okayama, 2024

… 3 The role of NPY in the pathogenesis of idiopathic pulmonary fibrosis (IPF). In healthy lungs, neuropeptide Y (NPY) is secreted from bronchial epithelial cells and maintains lung homeostasis via the Y1 receptor (Y1R) on type II alveolar epithelial …

  • I気道免疫応答を介した呼吸器疾患の発症における神経ペプチド Y の役割




Pirfenidone and Nintedanib exert additive antifibrotic effects by the SPP1-AKT pathway in macrophages and fibroblasts

C Meng, G Fan, J Liu, N Tao, T Sun - Biochemical and Biophysical Research …, 2024

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive disease with high mortality … Idiopathic pulmonary fibrosis (IPF) is a prevalent pulmonary disorder characterized by an … The incidence of IPF varies across different geographical …

  • ピルフェニドンとニンテダニブは、マクロファージと線維芽細胞の SPP1-AKT 経路によって相加的な抗線維化効果を発揮します




24/04/28

 

A preoperative use of manual therapy in a patient with idiopathic pulmonary fibrosis awaiting lung transplant: a case report

B Moody Jones, A Walsh, KL Bishop - Physiotherapy Theory and Practice, 2024

… This case report describes the outcomes of a patient with idiopathic pulmonary fibrosis (IPF) treated with manual therapy (MT) in an outpatient physical therapy setting. IPF is a life-threatening interstitial lung disease, often … There is little …

  • 肺移植を待つ特発性肺線維症患者における術前徒手療法の使用:症例報告




Antifibrotic treatment adherence, efficacy and outcomes for patients with idiopathic pulmonary fibrosis in Spain: a real-world evidence study

ADR Ortiz, BM Jiménez-Rodríguez, C López-Ramírez… - BMJ open respiratory …, 2024

Idiopathic pulmonary fibrosis (IPF) is a rare disorder associated with increased mortality and morbidity. There are currently two drugs approved for IPF … Methods: An observational, multicentre, prospective study was carried out among patients with …

  • スペインにおける特発性肺線維症患者に対する抗線維化治療のアドヒアランス、有効性、転帰:現実世界での証拠研究




Protection of Qingfei Xieding prescription from idiopathic pulmonary fibrosis by regulating renin-angiotensin and ferroptosis in MLE-12 cells

L Sun, X He, J Kong, J Zhou - Histology and histopathology

Idiopathic pulmonary fibrosis (IPF) is a lifelong lung disease, but there is no specific drug for treatment. … idiopathic pulmonary fibrosisby regulating renin-angiotensin through blocking ferroptosis. This research offers evidence for the potentiality of QF …

  • MLE-12細胞におけるレニン・アンジオテンシンおよびフェロトーシスの制御による特発性肺線維症からのQingfei Xieding処方の保護




Update on extraesophageal manifestations of gastroesophageal reflux

AM Fernandez, WW Chan - Current Opinion in Gastroenterology, 2024

… In a recent study of 124 idiopathicpulmonary fibrosis (IPF) patients who underwent MII-pH … Indeed, prior studies of bronchoalveolar lavage (BAL) fluid of IPF and lung transplant patients … of 125 mildmoderate IPF patients who underwent …

  • 胃食道逆流症の食道外症状に関する最新情報




[HTML] Elucidating the Molecular Pathways and Therapeutic Interventions of Gaseous Mediators in the Context of Fibrosis

A Li, S Wu, Q Li, Q Wang, Y Chen - Antioxidants, 2024

… Among idiopathic interstitial pneumonia, idiopathic pulmonary fibrosis (IPF) stands out as the most frequently encountered subtype, characterized by chronic and progressive fibrogenesis, primarily affecting individuals of advanced age [24] …

  • 線維症におけるガス状メディエーターの分子経路と治療介入の解明





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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。

当面、毎週アラートの内容をアップしていこうと思います。

 

癒しの音楽をお届けいたします。 

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