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[HTML] Epigenetics Approaches toward Precision Medicine for Idiopathic Pulmonary Fibrosis: Focus on DNA Methylation
WI Effendi, T Nagano - Biomedicines, 2023
… the development of idiopathic pulmonary fibrosis (IPF). Among all the epigenetic
marks, DNA methylation modifications have been the most widely studied in IPF.
This review summarizes the current knowledge concerning DNA methylation …
- 特発性肺線維症のプレシジョン・メディシンに向けたエピジェネティックス・アプローチ：DNAメチル化に焦点を当てる
Weight loss in nintedanib-treated patients with idiopathic pulmonary fibrosis
H Tomioka, M Iwabayashi, M Yokota, R Hashimoto… - Pulmonary Pharmacology & …, 2023
… Nintedanib is approved for the treatment of idiopathic pulmonary fibrosis (IPF).
Weight loss is recognized as an adverse event during … of IPF. Here, we report a
single-center, retrospective cohort study to assess body weight changes during …
- ニンテダニブ治療を受けた特発性肺線維症患者の体重減少
Evaluating the consistency with guideline recommendations for diagnosis and management of idiopathic pulmonary fibrosis in non-academic settings.
J De Andrade, T Luckhardt, S Sonavane, DR Crowe… - Sarcoidosis, Vasculitis, and …, 2023
… Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with elevated
mortality. Delay in diagnosis lead to worse outcomes. Guidelines developed at
academic medical … Our findings suggest that consistency with the IPF guidelines is …
- 非学術的設定における特発性肺線維症の診断と管理に関するガイドラインの推奨事項との一貫性の評価。
[PDF] Identification of Novel Necroptosis and Immune Infiltration in the Progression of Idiopathic Pulmonary Fibrosis
H Fan, L Luo - 2023
… In this study, we used bioinformatic methods to analyze the biological pathways
and hub genes associated with necroptosis, which are linked to the progression of
IPF. Our goal was to create a unique prognostic signature using these genes and to …
- 特発性肺線維症の進行における新規ネクロプトーシスと免疫浸潤の同定
Origins of Pathological Myofibroblasts in Lung Fibrosis: Insights from Lineage Tracing Mouse Models in the Single Cell RNA Sequencing Era
M Homps-Legrand, B Crestani, AA Mailleux - … Journal of Physiology-Lung Cellular and …, 2023
… pathological myofibroblasts in pulmonary fibrosis is not fully understood to date.
Lineage 49 … An official ATS/ERS/JRS/ALAT statement: 517 idiopathic pulmonary
fibrosis: evidence‐based guidelines for diagnosis and management. Am J 518 …
- 肺線維症における病理学的筋線維芽細胞の起源: 単一細胞 RNA シーケンシング時代の系統追跡マウスモデルからの洞察
[PDF] Validation of a Novel Clinical Dyspnea Scale–A Retrospective Pilot Study
M Kalluri, Y Cui, T Wang, JA Bakal - American Journal of Hospice and Palliative …, 2023
… Over 90% of patients with Idiopathic Pulmonary Fibrosis (IPF), the most common
form of … In this study, we examine the validity of EDI scores for assessing dyspnea
in patients with IPF. … with IPF; specifically, item scores would be associated with …
- 新しい臨床呼吸困難スケールの検証 - レトロスペクティブ パイロット研究
[PDF] Peculiarities of pulmonary rehabilitation in patients with chronic respiratory diseases in palliative and hospice care
ОМ Разнатовська, ВІ Петренко - Туберкульоз, легеневі хвороби, ВІЛ-інфекція, 2023
… It was found that today pulmonary rehabilitation in palliative patients is used only
for chronic obstructive pulmonary diseases, interstitial lung diseases, cystic fibrosis,
sarcoidosis, idiopathic pulmonary fibrosis and bronchiectasis. At the same time, the …
[HTML] COVID-19 Vaccine-Associated Pneumonitis in the Republic of Korea: A Nationwide Multicenter Survey Study
H Yoo, SY Kim, MS Park, SH Jeong, SW Park, HL Lee… - Journal of Korean Medical …, 2023
… ten patients with acute exacerbation of idiopathic pulmonary fibrosis from their
center, acute … with acute exacerbation of IPF and other ILDs such as idiopathic
nonspecific interstitial … The result suggests that COVID-19 vaccine may be a …
- 韓国におけるCOVID-19ワクチン関連肺炎：全国多施設調査研究
[HTML] Absence of HDAC3 by Matrix Stiffness Promotes Chromatin Remodeling and Fibroblast Activation in Idiopathic Pulmonary Fibrosis
F Toscano-Marquez, Y Romero, M Espina-Ordoñez… - Cells, 2023
… Therefore, the aim of this project was to determine the influence of HDAC3 on
chromatin remodeling and gene expression associated with idiopathic pulmonary
fibrosis. Our results show that HDAC3 is decreased in the nucleus of IPF fibroblasts …
[PDF] Multiple complications of advanced IPF in an individual patient presentation
T Ledger, S Braude - Respirology Case Reports, 2023
… We report a patient with advanced idiopathic pulmonary fibrosis (IPF), who in a
single presentation experienced three complications of the … This case also
highlights the importance in IPF patients of considering pneumomediastinum as a …
- 個々の患者のプレゼンテーションにおける進行した IPF の複数の合併症 ング
Imaging Fibrosis
A Sviridenko, G di Santo, I Virgolini - PET Clinics, 2023
… Another recent study has evaluated the potential of FAPI tracer in detecting of IPF
in a murine model. Pulmonary fibrosis was induced by … One recent case report
revealed a potential role for 68 Ga-FAPI-04 in idiopathic retroperitoneal fibrosis. In …
- 線維症のイメージ
[HTML] Thalidomide interaction with inflammation in idiopathic pulmonary fibrosis
NN Dsouza, V Alampady, K Baby, S Maity… - Inflammopharmacology, 2023
… inflammation by repurposing thalidomide for the treatment of idiopathic
pulmonary fibrosis (IPF). Articles were searched from the Scopus … thalidomide
relevant to IPF. Inflammation, oxidative stress, and epigenetic mechanisms are …
- 特発性肺線維症における炎症とサリドマイドの相互作用
[HTML] Prognostic role of CHA2DS2-VASc score for mortality risk assessment in non-advanced idiopathic pulmonary fibrosis: a preliminary observation
A Sonaglioni, A Caminati, M Re, D Elia, R Trevisan… - Internal and Emergency …, 2023
… However, no previous study considered this score as a prognostic indicator in non-AF
patients with mild-to-moderate idiopathic pulmonary fibrosis (IPF). All consecutive
non-AF patients with mild-to-moderate IPF, diagnosed between January 2016 and …
- 非進行性特発性肺線維症における死亡リスク評価のためのCHA2DS2-VAScスコアの予後的役割：予備的観察
Disease stage-related survival in idiopathic pulmonary fibrosis patients treated with nintedanib and pirfenidone: an exploratory study
M BOCCHINO, D BRUZZESE, G SCIOSCIA… - Respiratory Medicine and …, 2023
Background GAP (gender-age-physiology) and TORVAN are multi-parametric
prognostication scores for idiopathic pulmonary fibrosis (IPF). We compared their
prognostic value in patients treated with nintedanib or pirfenidone and explored their …
- ニンテダニブとピルフェニドンで治療された特発性肺線維症患者の病期に関連した生存率：探索的研究
Variability in MUC5B Expression Is Dependent on Genotype and Endotype in Idiopathic Pulmonary Fibrosis
AJ Ghosh, M Moll, BD Hobbs, J Cardwell, A Saferali… - American Journal of …, 2023
… obstructive pulmonary disease and idiopathic pulmonary fibrosis. Respir Res
2022;23:97. 7. … Genetic variants associated with susceptibility to idiopathic
pulmonary fibrosis in people of … Genome-wide association study of susceptibility …
- MUC5B 発現の変動性は、特発性肺線維症の遺伝子型とエンドタイプに依存する
Change in gait speed and adverse outcomes in patients with idiopathic pulmonary fibrosis: A prospective cohort study
CM Nolan, SJ Schofield, M Maddocks, S Patel… - Respirology, 2023
… Gait speed is associated with survival in individuals with idiopathic pulmonary
fibrosis (IPF). The extent to which four-metre gait speed (4MGS) decline predicts
adverse outcome in IPF remains unclear. We aimed to examine longitudinal 4MGS …
[HTML] An explainable machine learning-driven proposal of pulmonary fibrosis biomarkers.
D Fanidis, V Pezoulas, D Fotiadis, V Aidinis - Computational and Structural …, 2023
… Research of idiopathic pulmonary fibrosis, the most lethal among the interstitial
lung diseases, is in need for new biomarkers and potential disease targets, a goal
that could be accelerated using machine learning techniques. In this study, we have …
- 肺線維症バイオマーカーの説明可能な機械学習主導の提案。
[HTML] Transbronchial lung cryobiopsy and pulmonary fibrosis: A never-ending story?
B Ruaro, S Tavano, P Confalonieri, R Pozzan… - Heliyon, 2023
… Idiopathic pulmonary fibrosis (IPF) is the most common type of PF, with about
50,000 new cases diagnosed each year. The … in Idiopathic Pulmonary Fibrosis.
The following keywords or synonyms were used to carry out the search: “IPF …
- 経気管支肺凍結生検と肺線維症：終わりのない物語？
GB0139 (formerly TD139): A potential therapeutic for IPF?
RD WAB
… Idiopathic pulmonary fibrosis (IPF) is a lung disorder characterized by … IPF is TD-139.
Here, we delve deeper into the mechanism by which this drug functions and its
current status within clinical trials, aiming to simplify concepts and provide hope for …
- IPFの潜在的な治療法は?
[PDF] Vascular BMPRs Strike Out the Rolling Ball of Fibrosis
PL Brazee, RS Knipe - American Journal of Respiratory and Critical Care …, 2023
… Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease in which normal
lung tissue is progressively replaced with persistent scar, resulting in shortness of
breath, reduced lung function, and death with a median survival of approximately 4 …
- 血管 BMPR は線維症のローリング ボールを攻撃する
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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
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