ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です！と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この１年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。
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24/01/20
Unraveling the interplay between vital organelle stress and oxidative stress in idiopathic pulmonary fibrosis
A Mohanan, KR Washimkar, MN Mugale - … et Biophysica Acta (BBA)-Molecular Cell …, 2024
… Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease … of IPF. ER stress occurs when the protein folding capacity of the ER is overwhelmed, triggering the unfolded protein response (UPR) and contributing to protein …
- 特発性肺線維症における重要な細胞小器官ストレスと酸化ストレスの間の相互作用の解明
Integrating network pharmacology, experimental validation and molecular docking to reveal the alleviation of Yinhuang granule on idiopathic pulmonary fibrosis
Z Wu, R Shi, S Yan, S Zhang, B Lu, Z Huang, L Ji - Phytomedicine, 2024
Background Idiopathic pulmonary fibrosis(IPF) is a chronic disease characterized by the abnormal proliferation of fibroblast and excessive deposition of extracellular matrix (ECM), accompanied by inflammation and ultimately respiratory failure …
- ネットワーク薬理学、実験的検証、分子ドッキングを統合して、特発性肺線維症に対する銀黄顆粒の軽減を明らかにする
The tolerability and efficacy of antifibrotic therapy in patients with idiopathic pulmonary fibrosis: Results from a real-world study
R Zhao, B Xie, X Wang, X Zhang, Y Ren, C Wang… - Pulmonary Pharmacology & …, 2024
… We recruited patients with idiopathicpulmonary fibrosis treated with pirfenidone or nintedanib at China-Japan Friendship Hospital from February 2017 to February 2022. We investigated the medication situation, adverse reactions, tolerability and …
- 特発性肺線維症患者における抗線維化療法の忍容性と有効性: 実世界研究の結果
[HTML] Functional Progression after Dose Suspension or Discontinuation of Nintedanib in Idiopathic Pulmonary Fibrosis: A Real-Life Multicentre Study
B Ruaro, A Salotti, N Reccardini, S Kette, B Da Re… - Pharmaceuticals, 2024
… Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial … , IPF clinical features, NTD therapeutic dosage, tolerability and adverse events, pulmonary function tests (PFTs), the duration of treatment upon discontinuation, and the causes of interruption …
- 特発性肺線維症におけるニンテダニブの休薬または中止後の機能的進行：実際の多施設共同研究
Research Progress in experimental models of Idiopathic Pulmonary Fibrosis
李智慧， 余学庆， 杨曙光， 于宁霞， 臧丹阳 - 中国实验动物学报 (英文版)
… The incidence of IPF is increasing year by year, with high mortality and poor prognosis. At present, the pathogenesis of IPF is still unclear, and its treatment measures are limited. The experimental model is a key tool for further studying the …
- 特発性肺線維症の実験モデルにおける研究の進歩
Retrospective analysis of patients hospitalized with acute exacerbation of idiopathic pulmonary fibrosis
HÇ Erten, EE Gülşen, A Fidan, E Ay Talan, AC Şen… - Eurasian Journal of Pulmonology
… Idiopathic pulmonary fibrosis (IPF) is a disease of unknown etiology, chronic, and progressive lung disease. Acute exacerbation of IPF (AE-IPF) can cause sudden deterioration in the prognosis of the disease and is responsible for a significant …
- 特発性肺線維症の急性増悪で入院した患者の遡及的分析
The Spectrum of Sleep-related Breathing Disorders in Idiopathic Pulmonary Fibrosis
G Vayısoğlu Şahin, Ö Yalnız, G Polat, E Yalnız… - Eurasian Journal of Pulmonology
… in patients with idiopathic pulmonaryfibrosis (IPF) compared to … in IPF patients with and without SRBD is highly needed. The purpose of this study is to analyze the prevalence and types of SRBD in IPF patients, and to investigate and compare the …
- 特発性肺線維症における睡眠関連呼吸障害のスペクトル
Diagnostic value of combining high resolution computed tomography with pulmonary artery systolic pressure for assessment of idiopathic pulmonary fibrosis
AM Ali, MA Abdelnaaem, S Ragaey - Minia Journal of Medical Research, 2024
… for evaluating individuals with idiopathicinterstitial pneumonia (IIP). Individuals diagnosed with idiopathic pulmonary fibrosis (IPF) commonly … Methods: Our study involved a thorough examination of 40 individuals who had been diagnosed with …
- 特発性肺線維症の評価における高解像度コンピューター断層撮影と肺動脈収縮期圧の組み合わせの診断価値
Lactate accumulation induced by Akt2‐PDK1 signaling promotes pulmonary fibrosis
Z Sun, Z Ji, W He, R Duan, J Qu, G Yu - The FASEB Journal, 2024
… Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease with an abnormal accumulation of fibrotic tissue in the lung parenchyma and elevated glycolysis level in associated cells without effective therapy options. Lactate accumulation …
- Akt2-PDK1シグナル伝達によって誘導される乳酸蓄積は肺線維症を促進する
24/01/17
[HTML] In Vivo and In Vitro Pro-Fibrotic Response of Lung-Resident Mesenchymal Stem Cells from Patients with Idiopathic Pulmonary Fibrosis
G Escarrer-Garau, A Martín-Medina, J Truyols-Vives… - Cells, 2024
… Lung-resident mesenchymal stem cells (LR-MSC) are thought to participate in idiopathicpulmonary fibrosis (IPF) by differentiating into … IPF patients were included in this study according to the guidelines followed for IPFdiagnosis based …
- 特発性肺線維症患者由来の肺常在間葉系幹細胞の in vivo および in vitro 線維化促進反応
[HTML] Morphine for treatment of cough in idiopathic pulmonary fibrosis (PACIFY COUGH): a prospective, multicentre, randomised, double-blind, placebo-controlled, two-way …
Z Wu, LG Spencer, W Banya, J Westoby, VA Tudor… - The Lancet Respiratory …, 2024
… Background Idiopathic pulmonary fibrosisis a progressive fibrotic lung disease, with most … with placebo as an antitussive therapy in individuals with idiopathic pulmonary fibrosis. … Eligible patients aged 40–90 years had a diagnosis of …
[HTML] Idiopathic pulmonary fibrosis-specific Bayesian network integrating extracellular vesicle proteome and clinical information
M Tomoto, Y Mineharu, N Sato, Y Tamada… - Scientific Reports, 2024
… Idiopathic pulmonary fibrosis (IPF) is a progressive disease characterized by severe lung fibrosis and a poor prognosis. Although the biomolecules related to IPF … , and clinical findings from 206 patients with IPF and 36 controls. Differential protein …
- 細胞外小胞プロテオームと臨床情報を統合した特発性肺線維症特異的ベイジアンネットワーク
Leech extract alleviates idiopathic pulmonary fibrosis by TGF-β1/Smad3 signaling pathway
Y Zhang, YB Lu, WJ Zhu, X Gong, R Qian, YJ Lu, Y Li… - Journal of …, 2024
… Leech, as a traditional Chinese medicine for the treatment of blood circulation and blood stasis, was also widely used to cure pulmonaryfibrosis … in patients with idiopathicpulmonary fibrosis (IPF). However, the material basis of the leech in the …
- ヒル抽出物はTGF-β1/Smad3シグナル伝達経路により特発性肺線維症を軽減
[HTML] Alpinetin ameliorates bleomycin-induced pulmonary fibrosis by repressing fibroblast differentiation and proliferation
H Chen, C Liu, Y Zhan, Y Wang, Q Hu, Z Zeng - Biomedicine & Pharmacotherapy, 2024
… Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible interstitial lung disease with a poor prognosis. Alpinetin (ALP), derived from Alpinia … However, the utilization of ALP in managing pulmonary fibrosis and its underlying mechanisms …
- アルピネチンは線維芽細胞の分化と増殖を抑制することでブレオマイシン誘発性肺線維症を改善
Opioids bring peace to patients with IPF cough
DL Sykes, SP Hart - The Lancet Respiratory Medicine, 2024
… There are now two positive, randomised, placebo-controlled phase 2 trials of opioid treatment for cough in patients with idiopathicpulmonary fibrosis (IPF). Opioids suppress cough by binding to several types of G protein-coupled endorphin …
- オピオイドはIPF咳患者に安らぎをもたらす
Ivermectin ameliorates bleomycin-induced lung fibrosis in male rats by inhibiting the inflammation and oxidative stress
F Habibi Razi, R Mohammad Jafari, MA Manavi… - Immunopharmacology and …, 2024
… Idiopathic pulmonary fibrosis (IPF) is a pulmonary fibrotic disease characterized by a poor prognosis, which its pathogenesis involves the accumulation of abnormal fibrous tissue, inflammation, and oxidative stress. Ivermectin, a positive allosteric …
- イベルメクチンは、炎症と酸化ストレスを阻害することにより、雄ラットのブレオマイシン誘発性肺線維症を改善します
[PDF] Massive saddle embolus following bilateral lung transplantation discovered with transesophageal echocardiogram
A Bui, J Hasoon, S Markan, A Nguyen - Anaesthesiology Intensive Therapy, 2024
… It has been performed for patients with end-stage chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, pulmonary … The patient had obesity, type 2 dia betes mellitus, hypertension, chronic kidney disease stage 2, and idiopathic …
- 両側肺移植後の大規模なサドル塞栓が経食道心エコー検査で発見
24/01/16
[HTML] Identification of cuproptosis-related diagnostic biomarkers in idiopathic pulmonary fibrosis
Q Wang, Y Shang, Y Li, X Li, X Wang, Y He, J Ma… - Medicine, 2024
… Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease with clinical and pathological heterogeneity. Recent studies … However, the role of cuproptosis-related genes in the pathogenesis of IPF is still unclear. Two IPF …
- 特発性肺線維症におけるキュプロトーシス関連の診断バイオマーカーの同定
[PDF] Treatment of idiopathic pulmonary fibrosis and progressive pulmonary fibrosis: A position statement from the Thoracic Society of Australia and New Zealand 2023 …
JA Mackintosh, G Keir, LK Troy, AE Holland, C Grainge… - Respirology, 2023
… of Idiopathic Pulmonary Fibrosis (IPF). This paper was published contemporaneously with access to subsidized anti-fibrotic therapy, for patients with IPF. … the recent subsidized listing of nintedanib for non-IPF progressive pulmonary …
- 特発性肺線維症および進行性肺線維症の治療：オーストラリアおよびニュージーランド胸部学会の2023年改訂版の見解表明
[PDF] Genome-wide SNP-sex interaction analysis of susceptibility to idiopathic pulmonary fibrosis
…, CleanUP-IPF Investigators of the Pulmonary Trials … - medRxiv, 2024
… Background Idiopathic pulmonary fibrosis(IPF) is a chronic lung condition that is more prevalent in males than females. The … IPFsusceptibility and assess whether there is a need to consider sex-specific effects when evaluating genetic risk in …
- 特発性肺線維症に対する感受性のゲノムワイドなSNP-性相互作用解析
Imaging of pulmonary fibrosis in children: A review, with proposed diagnostic criteria
EM DeBoer, JP Weinman, J Ley‐Zaporozhan, M Griese… - Pediatric Pulmonology, 2024
… A systematic approach to characterizing adult fibrosis, with incorporation of imaging-based phenotypes, was pivotal in the development of the antifibrotic treatments nintedanib and pirfenidone, which are approved for the treatment of …
- 小児における肺線維症の画像化: 提案された診断基準を含むレビュー
Appraising the influence of dietary factors on the risk of idiopathic pulmonary fibrosis: a Mendelian randomization study
D Wu, T Wang, X Zhang - Frontiers in Genetics
… Background: Idiopathic pulmonary fibrosis(IPF) is a chronic disease associated with aging. Diet is known to influence the risk of age-… dietary factors and IPF remains unclear. The aim of our study was to assess the potential causal impact of …
- 特発性肺線維症のリスクに対する食事要因の影響の評価: メンデルランダム化研究
Integrating Fecal Metabolomics and Intestinal Microbiota to Study the Mechanism of Cannabidiol in the Treatment of Idiopathic Pulmonary Fibrosis
M Sun, F Zhang, F Lu, D Yu, Y Wang, P Chen, S Liu - Frontiers in Pharmacology
… Idiopathic pulmonary fibrosis is a chronic interstitial lung disease characterized by excessive deposition of … pulmonary fibrosismodel, combined with UPLC-Q-TOF/MS metabolomics and 16S rDNA sequencing, to explore cannabidiol's mechanism in …
- 特発性肺線維症の治療におけるカンナビジオールのメカニズムを研究するための糞便メタボロミクスと腸内細菌叢の統合
Macrolides and Interstitial Lung Diseases
Y Hara, T Kaneko - Macrolides as Immunomodulatory Agents, 2024
… Mechanisms that lead to increased microbial burden and reduced diversity of microbiota in lungs with idiopathic pulmonary fibrosis (IPF). Reproduced from Ntolios P et al [13]. Composition of the lung microbiome has been reported to …
- マクロライドと間質性肺疾患
Analysis of Validation Performance of a Machine Learning Classifier in Interstitial Lung Disease Cases Without Definite or Probable Usual Interstitial Pneumonia …
M Chang, JJ Reicher, A Kalra, M Muelly, Y Ahmad - Journal of Imaging Informatics in …, 2024
… idiopathic pulmonary fibrosis (IPF) diagnosis. The system incorporates an automated deep learning algorithm that analyzes chest computed tomography (CT) imaging to assess for features associated with idiopathicpulmonary fibrosis. … UIP …
肺線維症に対する抗線維化薬開発: がんと線維化肺の接点を捉えたトランスレーショナルリサーチ
西岡安彦 - 医学のあゆみ, 2024
… Idiopathic pulmonary fibrosis(IPF)is a chronic and progressive lung fibrotic disease belonging to idiopathic interstitial pneumonias. The 5-year survival of IPF is poor to be 30 to 50%, and therefore novel therapy has been required. From the …
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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
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