AIとIPFと癒しの音楽

特発性肺線維症 idiopathic pulmonary fibrosis (IPF)患者によるIPF関連学術情報の収集とシェア。癒しの音楽もお届けしています。

IPF Weekly Update

ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です!と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この1年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。

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24/01/13

 

[PDF] Molecular mechanisms of idiopathic pulmonary fibrosis: Emerging therapeutic approaches

VS Araujo, AM de Paula Siqueira, CS Teixeira… - Seven Editora, 2024

Idiopathic Pulmonary Fibrosis (IPF) stands as one of the most puzzling interstitial lung diseases within respiratory medicine, marked by a relentless progression that impairs lung function. Despite its elusive etiology, recent breakthroughs in molecular …

  • 特発性肺線維症の分子機構:新たな治療アプローチ




Risk factors for progression of pulmonary fibrosis: a single-centered, retrospective study

J Gu, S Xiao, M Jia, G Han - Frontiers in Medicine

… associated with the prevalence of progressive pulmonary fibrosis (PPF) in interstitial … -idiopathic pulmonary fibrosis idiopathicinterstitial pneumonia (non-IPF IIP), and 35 (11.4%) had hypersensitivity pneumonitis (HP). Overall, 118 (38.4%) …

  • 肺線維症進行の危険因子:単一施設の後ろ向き研究




[HTML] GDF15 as a potential biomarker to distinguish fibrotic from non-fibrotic hypersensitivity pneumonitis

A Alarcon-Dionet, A Ruiz, L Chavez-Galan… - Scientific Reports, 2024

Hypersensitivity Pneumonitis (HP) is an immune-mediated interstitial lung disease (ILD) characterized by fibrotic HP (fHP) or non-fibrotic HP (non-fHP). Fibrosis is associated with poor prognosis, emphasizing the need for biomarkers to distinguish fHP from …

  • 線維性過敏性肺炎と非線維性過敏性肺炎を区別するための潜在的なバイオマーカーとしての GDF15




Diagnosis of interstitial lung diseases: from Averill A. Liebow to artificial intelligence

SY Eunhee, P Wawryko, JH Ryu - Journal of Pathology and Translational Medicine

… Histopathologic criteria of usual interstitial pneumonia (UIP)/idiopathic pulmonary fibrosis(IPF) were defined over the years and endorsed … of UIP/IPF. Two antifibrotic agents introduced in the mid-2010s opened a new era of therapeutic …

  • 間質性肺疾患の診断: アベリル・A・リーボーから人工知能まで




Gene Expression Meta-Analysis Reveals Aging and Cellular Senescence Signatures in Scleroderma-associated Interstitial Lung Disease

M Yang, S Lee, J Neely, M Hinchcliff, P Wolters… - Frontiers in Immunology

… Aging and cellular senescence are increasingly recognized as key contributors to pulmonary fibrosis. However, our understanding in the … TL in SSc-ILD was comparable to idiopathic pulmonary fibrosis, a disease of known aberrant aging …

  • 遺伝子発現メタアナリシスにより、強皮症関連間質性肺疾患における老化と細胞老化の特徴が明らかに




[PDF] The association of vitamin D and fibrotic disease: a Mendelian randomization Study

Q Xie, M Wang, X Zhao, Y Lu, M Li, X He, S Shuai - 2024

… with idiopathic pulmonary brosis (IPF) and the healthy control group. It is worth mentioning that in another two-sample Mendelian randomization analysis, a different database was used for the analysis, and it also reported no causal …

  • ビタミン D と線維性疾患の関連性: メンデルランダム化研究

 

 



24/01/11

 

[PDF] Use of Nintedanib and its Outcome among Post-COVID Pulmonary Fibrosis Patients Residing at High Altitudes: A Case Series

A Pal, AK Mishra, MK Yadav, RM Giri, KB Shah - Int Clinc Med Case Rep Jour. 2023; 2 (18) …

pulmonary fibrosis. Antifibrotic drugs, such as Nintedanib, have emerged as an early treatment option for prevention and during post-COVID-19 pulmonary fibrosis … unit (ICU) admission, at the dose of Idiopathic Pulmonaryfibrosis (IPF). The dose …




[HTML] Supporting self-management for patients with Interstitial Lung Diseases: Utility and acceptability of digital devices

MA Althobiani, R Shuttleworth, J Conway, J Dainton… - PLOS Digital Health, 2024

… The utilization of digital health tools to assist patients with ILD, specifically, idiopathicpulmonary fibrosis (IPF), has risen in the United … using home-monitoring devices in patients with idiopathic pulmonary fibrosis(IPF). European Respiratory …

  • 間質性肺疾患患者の自己管理のサポート:デジタルデバイスの有用性と受容性




MAIT cells protect against sterile lung injury

X Zhang, S Li, W Lason, M Greco, P Klenerman… - bioRxiv, 2024

… Human scRNA-seq data revealed that MAIT cells were activated, with increased cDC populations in idiopathic pulmonary fibrosispatients. Thus, MAIT cells enhance defence against sterile lung injury by fostering cDC1-driven anti-fibrotic pathways. …

  • MAIT 細胞は無菌肺損傷から保護




患者由来の筋線維芽細胞を用いた新規肺線維症治療法の探索

平木基也, 小川秀己, 三澤智子, 中村浩之, 巽浩一郎… - 日本薬理学会年会要旨集 第 …, 2023

Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease of unknown etiology. Under pathological conditions in lungs with IPF, … To develop effective therapeutic interventions against IPF, dedifferentiation of MyoF has recently attracted …

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口腔咽頭吸引法によるブレオマイシン誘発肺線維症モデルマウスの作製およびニンテダニブの薬効評価

松木菜保子, 樋川奈穂美, 守住孝輔, 片山誠一, 西勝英… - 日本薬理学会年会要旨集 第 …, 2023

Idiopathic pulmonary fibrosis (IPF) is a progressive disease that causes respiratory failure. However, treatment for IPF is limited because there … Since it has been known that bleomycin, an anticancer drug, causes pulmonary fibrosis, IPF



24/01/09

 

Antifibrotic effects of vitamin D3 on human lung fibroblasts derived from patients with idiopathic pulmonary fibrosis

T Voisin, A Joannes, C Morzadec… - The Journal of Nutritional …, 2024

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease. Up to now, no treatment can stop the progression of IPFIPF. In this context, we determined if VD can prevent the pro-fibrotic functions of human lung …

  • 特発性肺線維症患者由来のヒト肺線維芽細胞に対するビタミンD3の抗線維化効果




CXCL6 in idiopathic pulmonary fibrosis: a novel mediator in the complex epithelial–mesenchymal crosstalk

DG Helou, B Crestani - European Respiratory Journal, 2024

Idiopathic pulmonary fibrosis (IPF) is the prototypic progressive disease of pulmonaryfibrosis [1, 2]. In the 20th century, … In idiopathic pulmonary fibrosis (IPF), ectopic secretory cells are the main producers of CXCL6 within the transformed …

  • 特発性肺線維症におけるCXCL6:複雑な上皮間葉クロストークにおける新規メディエーター




[PDF] Pulmonary vascular dysfunction without pulmonary hypertension: A distinct phenotype in idiopathic pulmonary fibrosis

SD Nathan, B Tehrani, Q Zhao, R Arias, D Kim… - Pulmonary Circulation, 2024

… hypertension (PH) has been observed in patients with idiopathic pulmonary fibrosis(IPF). We describe the prevalence and etiology of … with IPF. Hemodynamic, echocardiographic, and functional respiratory imaging (FRI) data was compared …

  • 肺高血圧症を伴わない肺血管機能不全:特発性肺線維症における独特の表現型




[HTML] Genetic association analysis of dietary intake and idiopathic pulmonary fibrosis: a two-sample mendelian randomization study

C Zhang, Y Xi, Y Zhang, P He, X Su, F Fan, M Wu… - BMC Pulmonary Medicine, 2024

IPF is a complex lung disease whose aetiology is not fully understood, but diet may have an impact on its development and progression. Therefore, we investigated the potential causal connection between dietary intake and IPF through TSMR to offer …

  • 食事摂取と特発性肺線維症の遺伝的関連分析: 2 サンプルのメンデルランダム化研究




[PDF] Assessing Causal Relationships Between Diabetes Mellitus and Idiopathic Pulmonary Fibrosis

ST Moss, C Minelli, OC Leavy, RJ Allen, N Oliver… - medRxiv, 2024

… What this study adds: Idiopathic pulmonaryfibrosis and diabetes mellitus are unlikely to be causally linked, suggesting … Idiopathicpulmonary fibrosis (IPF) is a chronic disease characterised by progressive and uncontrolled scarring of the lung …

  • 糖尿病と特発性肺線維症との因果関係の評価




Meaningful Endpoints for Idiopathic Pulmonary Fibrosis (IPF) Clinical Trials: Emphasis on'Feels, Functions, Survives'

G Raghu, M Ghazipura, TR Fleming, KI Aronson… - American Journal of …, 2024

Idiopathic pulmonary fibrosis: shifting the concept to irreversible pulmonary fibrosis of many … Idiopathic pulmonary fibrosis: lessons from clinical trials over the past 25 years. Eur Respir J … Laparoscopic anti-reflux surgery for the treatment of …

  • 特発性肺線維症(IPF)臨床試験の有意義なエンドポイント:「感触、機能、生存」に重点を置く




Real-world practice of idiopathic pulmonary fibrosis: Results from a 2000–2016 cohort

W Ying-Tso, S Te-Chun, L Cheng-Li, CY Tu, TC Hsia… - Open Medicine, 2023

… with idiopathic pulmonary fibrosis (IPF). We established an IPF cohort and a comparative cohort matched for sex, age, and the date of IPFdiagnosis. We … We included 921 patients in the IPF cohort and 3,677 individuals in the comparative …

  • 特発性肺線維症の実際の実践: 2000 ~ 2016 年のコホートの結果




[PDF] Predictive Biomarkers in Idiopathic Pulmonary Fibrosis: A Comprehensive Analysis for Early Diagnosis and Patient Stratification

DEN Rodriguez, KJL Romero, KA Ferrer, A Sam…

Abstract Idiopathic Pulmonary Fibrosis (IPF) presents a complex challenge in respiratory … diagnosis by unraveling distinct radiographic changes in IPF. Molecular biomarkers, such as … synthesis to comprehend the complexities of IPF

  • 特発性肺線維症の予測バイオマーカー: 早期診断と患者層別化のための包括的な分析




Extrapleural air secondary to idiopathic pulmonary fibrosis‐related pneumomediastinum

Y Nagata, T Watanabe, Y Tanabe, M Kato, T Shukuya… - Respirology Case Reports, 2024

… A 78‐year‐old man with a history of idiopathicpulmonary fibrosis was admitted to our hospital with a small left pneumothorax and mild pneumomediastinum. He was managed conservatively. Two weeks later, a chest x‐ray revealed a lesion …

  • 特発性肺線維症関連気縦隔症に続発する胸腔外空気




[HTML] ILD-GAP combined with the monocyte ratio could be a better prognostic prediction model than ILD-GAP in patients with interstitial lung diseases

M Hirata, Y Hara, H Fujii, K Murohashi, Y Saigusa… - BMC Pulmonary Medicine, 2024

… In ILD patients were included idiopathicpulmonary fibrosis (IPF), idiopathicnonspecific interstitial pneumonia (iNSIP), collagen vascular disease-related interstitial pneumonia (CVD-IP), chronic hypersensitivity pneumonitis (CHP), and …

  • ILD-GAPと単球比を組み合わせると、間質性肺疾患患者においてILD-GAPよりも優れた予後予測モデルとなる可能性

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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。

当面、毎週アラートの内容をアップしていこうと思います。

 

癒しの音楽をお届けいたします。 

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