AIとIPFと癒しの音楽

特発性肺線維症 idiopathic pulmonary fibrosis (IPF)患者によるIPF関連学術情報の収集とシェア。癒しの音楽もお届けしています。

IPF Weekly Update

ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です!と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この1年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。

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23/01/06

[HTML] Development of a Novel Biomarker for the Progression of Idiopathic Pulmonary Fibrosis

HJ Yeo, M Ha, DH Shin, HR Lee, YH Kim, WH Cho - International Journal of …, 2024

… The progression of idiopathic pulmonaryfibrosis (IPF) is diverse and unpredictable. We identified and validated a new biomarker for IPF… assessed differentially expressed genes in patients with advanced IPF compared with early …

  • 特発性肺線維症の進行を示す新規バイオマーカーの開発



[HTML] Modelling bronchial epithelial-fibroblast cross-talk in idiopathic pulmonary fibrosis (IPF) using a human-derived in vitro air liquid interface (ALI) culture

SL Barron, O Wyatt, A O'Connor, D Mansfield… - Scientific Reports, 2024

Idiopathic Pulmonary Fibrosis (IPF) is a severe and aggressive form of pulmonaryfibrosis … is not without risk, and the prognosis of death from IPF remains at 3–4 years. One reason for the … Additionally, the most commonly used in vivo models of …

  • ヒト由来の in vitro 気液界面 (ALI) 培養を使用した特発性肺線維症 (IPF) における気管支上皮線維芽細胞クロストークのモデル化



[HTML] The impact of respiratory reactance in oscillometry on survival in patients with idiopathic pulmonary fibrosis

T Ishikawa, H Nishikiori, Y Mori, K Fujino, A Saito… - BMC Pulmonary Medicine, 2024

Idiopathic pulmonary fibrosis (IPF) is a progressive disease with a poor prognosis. Pulmonary function tests (PFTs) aid in evaluating the disease status of IPF. The clinical significance of oscillometry measurements in interstitial lung diseases has …

  • オシロメトリーにおける呼吸リアクタンスが特発性肺線維症患者の生存に及ぼす影響



[HTML] Traditional Chinese medicine inspired dual-drugs loaded inhalable nano-therapeutics alleviated idiopathic pulmonary fibrosis by targeting early inflammation and late …

M Zheng, K Liu, L Li, C Feng, G Wu - Journal of Nanobiotechnology, 2024

… The results of this study will provide a powerful inhaled drug for IPF treatment and will benefit the prognosis of IPF. In addition, this study demonstrated a progressive strategy for the use of compound Chinese medicine and small molecule …

  • 伝統的な中国医学にヒントを得た吸入可能なナノ治療薬を配合した二剤併用により、初期の炎症と後期の線維症を標的とすることで特発性肺線維症を軽減



Frequency and characteristics of refractory dyspnea in idiopathic fibrosing interstitial pneumonia

N Bautin, J Ferlin, G Terce, C Ternynck, V Valentin… - Respiratory Medicine, 2024

… Our study aimed to assess the frequency and characteristics of refractory dyspnea in dyspneic patients with idiopathic pulmonary fibrosis(IPF) and idiopathic nonspecific interstitial … Health-related quality of life in patients with idiopathic

  • 特発性線維化性間質性肺炎における難治性呼吸困難の頻度と特徴



A Rare Case of Primary Sjogren's Syndrome with Idiopathic Pulmonary Fibrosis with Variable Presentations: A case report

A Yadav, RB Nepali, AMJ Alam - Mymensingh medical journal: MMJ, 2024

… We diagnosed and treated a case of Primary SjoGren's Syndrome with Idiopathic PulmonaryFibrosis (IPF) in a 65 years old woman who … We finally diagnosed a case of Primary SjoGren's syndrome with IPF and the patient was treated with …

  • さまざまな症状を呈する特発性肺線維症を伴う原発性シェーグレン症候群の稀な症例:症例報告



[PDF] Screening for central targets and the commonalities between rheumatoid arthritis and idiopathic pulmonary fibrosis based on bioinformatics

KT Lei, Z Wang, Y Lu, W Zhu, Y Wang - 2024

idiopathic pulmonary brosis (IPF), The precise molecular processes that underlie this correlation are yet to be fully comprehended. Hence, the objective of this research was to investigate the molecular workings of RA in conjunction with IPF



Mechanisms and management of cough in interstitial lung disease

AZ Rasheed, ML Metersky, F Ghazal - Expert Review of Respiratory Medicine, 2024

… The purpose of this review is to highlight mechanisms of chronic cough and to present therapeutic evidence for its management in the most commonly occurring diffuse fibrosing lung diseases including idiopathic pulmonaryfibrosis (IPF) …

  • 間質性肺疾患における咳のメカニズムと管理



Combined pulmonary fibrosis and emphysema

JD Caceres, A Venkata - Current Opinion in Pulmonary Medicine

… UIP is the radiologic pattern of idiopathicpulmonary fibrosis (IPF), and thus these patients were said to have emphysema plus IPF. The Cottin study specifically excluded patients with pulmonary fibrosis related to connective tissue disease. …



[HTML] Researching New Drug Combinations with Senolytic Activity Using Senescent Human Lung Fibroblasts MRC-5 Cell Line

MCX de Godoy, JA Macedo, A Gambero - Pharmaceuticals, 2024

… The combination of the drug dasatinib and the polyphenol quercetin is used in clinical trials as a senolytic, and the first results point to the relief of physical dysfunction in patients with idiopathicpulmonary fibrosis. In this work, we tested new …

  • 老化ヒト肺線維芽細胞MRC-5細胞株を使用した老化細胞破壊活性のある新薬の組み合わせの研究



24/01/03

 

[PDF] Inhibition of Pro-Fibrotic Molecules Expression in Idiopathic Pulmonary Fibrosis—Derived Lung Fibroblasts by Lactose-Modified Hyaluronic Acid Compounds

A Donato, A Di Stefano, N Freato, L Bertocchi, P Brun - Polymers, 2024

… Abstract: Idiopathic pulmonary fibrosis(IPF) is a chronic inflammatory and fibrotic pathological condition with undefined effective therapies … Primary human pulmonary fibroblasts obtained from normal and IPFsubjects activated with TGF-β …

  • 特発性肺線維症における線維化促進性分子の発現の阻害 - 乳糖修飾ヒアルロン酸化合物による肺線維芽細胞由来



[PDF] Herbal Remedies Effective on Treating Idiopathic Pulmonary Fibrosis

A Chaudhary, S Shukla, R Kumar, H Barti - Journal of Pharmaceutical Care, 2023

Idiopathic Pulmonary Fibrosis (IPF) poses a significant challenge in the realm of respiratory … This abstract delves into the efficacy of numerous herbal remedies in the treatment of IPF, … to improved oxygenation in individuals with IPF, offering …

  • 特発性肺線維症の治療に効果的な漢方薬



[HTML] First report of SAVI syndrome in Panama due variant of the STING1 gene in patient with emphysema and idiopathic pulmonary fibrosis

ED Austin-Ward, E Brid - Genetics and Clinical Genomics, 2023

Introduction: The STING gene (Stimulator of Interferon Genes) emerges as a key element in the understanding and management of hyperinflammation and autoimmune conditions. Case: We report an adolescent patient with a history of …

  • パナマにおける肺気腫および特発性肺線維症患者のSTING1遺伝子変異によるSAVI症候群の初報告



[PDF] circELP2 reverse‐splicing biogenesis and function as a pro‐fibrogenic factor by targeting mitochondrial quality control pathway

S Zhang, D Tu, W Liu, R Li, M Jiang, X Yuan, J Luan… - Journal of Cellular and …, 2023

Idiopathic pulmonary fibrosis (IPF) is an insidious and fatal interstitial lung disease accompanied by fibrotic response, including … mechanism of circELP2 in pulmonary fibrosisand evaluate the value of blocking circELP2- medicated signal …



The Impact of Air Pollution on Interstitial Lung Disease: A Systematic Review and Meta-analysis

D Lan, CC Fermoyle, LK Troy, LD Knibbs, TJ Corte - Frontiers in Medicine

… of the association between air pollution, and ILD, including idiopathic pulmonary fibrosis(IPF).We systematically searched from six online … We conducted meta-analyses to assess the estimated Risk Ratios (RRs) for acute exacerbations (AE)-IPF in …

  • 大気汚染が間質性肺疾患に及ぼす影響:系統的レビューとメタ分析



Multi-modal Learning and Its Application for Biomedical Data

J Liu, YD Zhang, H Cai - Frontiers in Medicine

… (3) differentiate between idiopathicpulmonary fibrosis (IPF) and non-IPF interstitial lung diseases (ILDs) in patients by multimodal analysis. Sato et al.(4) use multimodal learning to improve the quality of assessment for predicting the dose …

  • マルチモーダル学習と生体医療データへの応用



Progressive pulmonary fibrosis in myositis-specific antibody-positive interstitial pneumonia: a retrospective cohort study

H Wang, Y Wang, D Sun, S Yu, X Du, Q Ye - Frontiers in Medicine

… Objectives Idiopathic inflammatory myopathy (IIM) frequently coexists with interstitial pneumonia (IP) and is commonly the initial or sole … of progressive pulmonary fibrosis (PPF) and identify potential predictors influencing the …



[HTML] The Plastic Interplay between Lung Regeneration Phenomena and Fibrotic Evolution: Current Challenges and Novel Therapeutic Perspectives

S Lettieri, FR Bertuccio, L del Frate, F Perrotta… - International Journal of …, 2023

… The most prevalent kind of idiopathicinterstitial pneumonia is called idiopathicpulmonary fibrosis (IPF) [1,2], a chronic fibrotic illness of the lower respiratory tract that progresses relentlessly [1]. Usual interstitial pneumonia is the term used to …

  • 肺の再生現象と線維化の進展の間の可塑的相互作用: 現在の課題と新しい治療の展望



24/01/02

 

[HTML] A prospective cohort study of periostin as a serum biomarker in patients with idiopathic pulmonary fibrosis treated with nintedanib

M Okamoto, K Fujimoto, T Johkoh, A Kawaguchi… - Scientific Reports, 2023

… biomarker in patients with idiopathicpulmonary fibrosis (IPF) who received nintedanib. … Forty-three antifibrotic drug-naive patients with IPF described in previous studies were set as … and better therapeutic effectiveness in patients with …

  • ニンテダニブで治療を受けた特発性肺線維症患者における血清バイオマーカーとしてのペリオスチンの前向きコホート研究



[HTML] TRIOBP modulates β-catenin signaling by regulation of miR-29b in idiopathic pulmonary fibrosis

L Wang, W Zhao, C Xia, S Ma, Z Li, N Wang, L Ding… - Cellular and Molecular Life …, 2024

Idiopathic pulmonary fibrosis (IPF) is a fatal and devastating lung disease of unknown … In our previous study, we found that miR-29b has a therapeutic effect on pulmonary fibrosis. … might be a key anti-fibrotic axis in IPF to regulate lung …

  • TRIOBP は特発性肺線維症における miR-29b の制御により β-カテニンシグナル伝達を調節



AV Samarelli, R Tonelli, G Raineri, G Bruzzi… - Frontiers in Oncology

Idiopathic pulmonary fibrosis (IPF) severely affects the lung leading to aberrant deposition of extracellular matrix and … IPF lung tissue. The primary aim of this study was to explore the proteomic profiling yield of archived formalin-fixed paraffin-embedded …

  • ホルマリン固定パラフィン包埋組織のプロテオミクス解析により、特発性肺線維症の肺機能不全に関連する重要なタンパク質が明らかに



Real-life data in the treatment and follow-up of idiopathic pulmonary fibrosis: A single-center study.

F Üzer, S Akanlar, A Çilli - Tuberkuloz ve Toraks, 2023

… The aim of this study was to evaluate the real-life treatment and follow-up data of patients with idiopathic pulmonary fibrosis (IPF) in a … In this study evaluating patients with IPF under follow-up in our hospital, it was observed that the majority of …

  • 特発性肺線維症の治療と追跡調査における実際のデータ:単一施設研究。



Regulation of miRNA-155-5p ameliorates NETosis in pulmonary fibrosis rat model via inhibiting its target cytokines IL-1β, TNF-α and TGF-β1

RM Adel, H Helal, MA Fouad, SS Abd-Elhalem - International Immunopharmacology, 2024

Idiopathic pulmonary fibrosis (IPF) is an age-related inflammatory disease with no cure up till now. It is accompanied by neutrophils infiltration as the main responders to inflammation and fibrosis. Importantly, neutrophils release neutrophil extracellular …

  • miRNA-155-5pの制御は、標的サイトカインIL-1β、TNF-α、TGF-β1の阻害を介して肺線維症ラットモデルのNETosisを改善



[PDF] Clinical and Functional Characteristics of Interstitial Lung Disease in Algeria: A Single-Center Prospective Study

A Ketfi, F Selatni, C Djouadi, R Touahri - Journal of Respiration, 2024

… Patients with sarcoidosis, CTD, and hypersensitivity pneumonitis (HP) were younger, more often female, and often non-smokers compared to the group of patients with idiopathic pulmonary fibrosis (IPF) (Tables 2 and 3)]. Respiratory …

  • アルジェリアにおける間質性肺疾患の臨床的および機能的特徴:単一施設による前向き研究



[HTML] Unmasking a Silent Threat: Improving Pulmonary Hypertension Screening Methods for Interstitial Lung Disease Patients

V Averjanovaitė, L Gumbienė, I Zeleckienė… - Medicina, 2023

… To date, idiopathic pulmonary fibrosis (IPF) has been the most comprehensively investigated ILD in the context of PH. However, PH may … Comparison of radiological findings in idiopathicpulmonary fibrosis with thin-slices multi-detector …

  • 静かな脅威を明らかにする: 間質性肺疾患患者のための肺高血圧症スクリーニング方法の改善



 

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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。

当面、毎週アラートの内容をアップしていこうと思います。

 

癒しの音楽をお届けいたします。 

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