ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です!と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この1年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。
<><><>
23/10/21
Proteomic Biomarkers of Survival in Idiopathic Pulmonary Fibrosis
JM Oldham, Y Huang, S Bose, SF Ma, JS Kim… - American Journal of …, 2023
… Idiopathic Pulmonary Fibrosis (IPF) is a … of IPF after phase III clinical trials demonstrated efficacy in slowing lung function decline.(4, 5) While these drugs may impact outcomes, any survival benefit appears modest.(6, 7) Lung transplantation …
- 特発性肺線維症における生存のプロテオミクスバイオマーカー
Five-Repetition Sit-to-Stand Test: Responsiveness and Minimal Important Difference in Idiopathic Pulmonary Fibrosis
P Trivedi, S Patel, G Edwards, T Jenkins, WDC Man… - Annals of the American …, 2023
… Participants were people with idiopathicpulmonary fibrosis (IPF) who were prospectively and consecutively recruited from the Harefield Pulmonary Rehabilitation Unit, United Kingdom between March 2012 and December 2019 …
- 5 回反復座位-立位テスト: 特発性肺線維症における反応性と重要な最小差
[PDF] The causal relationship between C-reactive protein and idiopathic pulmonary fibrosis: A univariate and multivariate Mendelian randomization study
Q Yang, X Chen, Y Zhang, Q Wu - 2023
… Our ndings support a causal relationship between CRP and IPF, emphasizing the importance of monitoring femoral neck IPF in patients with chronic in ammatory conditions. … These discoveries provide valuable insights into the pathogenesis …
- C 反応性タンパク質と特発性肺線維症の因果関係: 単変量および多変量メンデルランダム化研究
[PDF] Comparison of Longevity in Patients with Idiopathic Pulmonary Fibrosis Using Pirfenidone Versus Triple Therapy with Prednisolone, Azathioprine, and Acetylcysteine
M Soleimanian Asl, Z Motakef, N Behgam, S Attaran… - TANAFFOS (Respiration), 2023
… In this study, we aimed to compare life expectancy in patients with idiopathicpulmonary fibrosis using triple treatments of prednisolone, … diagnosis of IPF, recruited from a lung subspecialty clinic in Mashhad, between 2016 and 2020 …
[HTML] Risk factor analysis of the development of severe radiation pneumonitis in patients with non-small cell lung cancer treated with curative radiotherapy, with focus on …
H Kim, J Hwang, SM Kim, J Choi, DS Yang - BMC Cancer, 2023
… Idiopathic pulmonary fibrosis (IPF) as an underlying lung disease (P < 0.001) and clinical stage, regarded as the concurrent use of … In multivariate analyses adjusting confounding variables, the presence of IPF as an underlying disease was …
[HTML] Small-Molecule Activation of Protein Phosphatase 2A Counters Bleomycin-Induced Fibrosis in Mice
M Pillai, P Lafortune, A Dabo, H Yu, SS Park, H Taluru… - ACS Pharmacology & …, 2023
… -threonine phosphatase, is reduced in the lung fibroblasts of idiopathic pulmonaryfibrosis (IPF) patients. The objective of this study was to … In conclusion, our study indicates that the decrease in PP2A activity, which occurs in fibroblasts from the …
- プロテインホスファターゼ 2A の小分子活性化がマウスのブレオマイシン誘発性線維症に対抗する
[PDF] Relationship Between Helicobacter Pylori Infection and Chronic Respiratory Disease: A Two-sample Mendelian Randomization Study
G Jia, T Guo, C He - 2023
… The IVW method showed that idiopathicpulmonary brosis (IPF) was associated with a H. pylori infection risk reduction (OR = 0.97; p = 0.041), which was not … Our study also found that IPF is a protective factor for H. pylori infection, while H. pylori …
- ヘリコバクター ピロリ感染と慢性呼吸器疾患の関係: 2 サンプルのメンデルランダム化研究
Influence of pulmonary rehabilitation on symptoms of anxiety and depression in interstitial lung disease: A systematic review of randomized controlled trials
B Luu, A Gupta, N Fabiano, S Wong, JG Fiedorowicz… - Respiratory Medicine
… Idiopathic pulmonary fibrosis (IPF) was the most common type of ILD (k = 3). One study reported clinically-significant improvements in … Idiopathic pulmonary fibrosis (IPF) was the most commonly included type of ILD (k = 3, 60 %). All five studies used …
23/10/19
[HTML] Molecular and Genetic Biomarkers in Idiopathic Pulmonary Fibrosis: Where Are We Now?
I Tomos, I Roussis, AM Matthaiou, K Dimakou - Biomedicines, 2023
… Idiopathic pulmonary fibrosis (IPF) represents a chronic progressive fibrotic interstitial lung … The identification of such blood biomarkers may also unravel novel drug targets against IPF … been investigated in IPF with various results …
- 特発性肺線維症における分子および遺伝的バイオマーカー: 私たちは今どこにいるか?
Implementing a PROM tool to improve the supportive care services referral patterns of adult idiopathic pulmonary fibrosis patients in a pulmonary clinic: A quality …
T FOWORA - 2023
… as Idiopathic pulmonary fibrosis (IPF) due to symptoms such as progressive dyspnea and fatigue, limitations on physical activities and social isolation [18]. The symptoms of IPF, … The American Thoracic Society (ATS) recommended a multi-faceted …
- 呼吸器クリニックにおける成人特発性肺線維症患者の支持療法サービス紹介パターンを改善するための PROM ツールの導入: 品質改善パイロット プロジェクト
[HTML] Outcomes and prognosis of progressive pulmonary fibrosis in patients with antineutrophil cytoplasmic antibody-positive interstitial lung disease
S Sakamoto, A Suzuki, S Homma, Y Usui, H Shimizu… - Scientific Reports, 2023
… Using data from the IIPs cohort at our institution, 63 patients with IPF and 79 with idiopathic nonspecific interstitial pneumonia (iNSIP) were identified and compared to those with ANCA-ILDs (ANCA-UIP, ANCA-NSIP). We also evaluated the …
- 抗好中球細胞質抗体陽性間質性肺疾患患者における進行性肺線維症の転帰と予後
Computational Models Of Extracellular Matrix Remodeling In Pulmonary Fibrosis
DT Casey - 2023
… Idiopathic pulmonary fibrosis (IPF) is a devastating, progressive and ultimately fatal … With few effective treatments, uncovering the pathogenesis of IPF may provide crucial information for … Here, we employ computational models to simulate …
- 肺線維症における細胞外マトリックス再構築の計算モデル
Heterogenous Intrapulmonary Distribution of Aerosolized Model Compounds in Mice with Bleomycin-Induced Pulmonary Fibrosis
K Togami, Y Kanehira, Y Yumita, H Ozaki, R Wang… - Journal of Aerosol Medicine …, 2023
… Background: A distinctive pathological feature of idiopathic pulmonary fibrosis (IPF) is the aberrant accumulation of extracellular matrix components in the alveoli in abnormal remodeling and reconstruction following scarring of the alveolar structure …
- ブレオマイシン誘発性肺線維症マウスにおけるエアロゾル化モデル化合物の肺内不均一分布
23/10/17
[PDF] Diagnostic approaches for idiopathic pulmonary fibrosis
JH Lee, JW Song - Tuberculosis and Respiratory Diseases, 2023
… of IPF is … IPF diagnosis process; the clinical probability of IPF is high if the suspected patient is 60 years or older, male, and has a history of cigarette smoking. Systemic assessment for connective tissue disease is essential in the initial …
- 特発性肺線維症の診断アプローチ
[HTML] Identification of Hub Genes in Idiopathic Pulmonary Fibrosis and Their Association with Lung Cancer by Bioinformatics Analysis
JM Velázquez-Enríquez, I Reyes-Avendaño… - Advances in Respiratory …, 2023
… Idiopathic pulmonary fibrosis (IPF) is a chronic disease of progressive and irreversible character. It is known as the most severe and common idiopathic interstitial pneumonia (IIP) [1,2]. To date, the pathogenesis of IPF has not been fully …
- バイオインフォマティクス解析による特発性肺線維症におけるハブ遺伝子の同定および肺がんとの関連
[HTML] Saikosaponin-d regulates angiogenesis in idiopathic pulmonary fibrosis through angiopoietin/Tie-2 pathway
Y Wu, J Zhang, X Wang, Y Xu, J Zheng - Acta Histochemica, 2023
… Idiopathic pulmonary fibrosis (IPF) is considered as a chronic interstitial lung disease with underlying mechanism of IPF remaining unclear, while there are no definitive … In recent years, scientists have gradually paid attention to the influence …
- サイコサポニン d はアンジオポエチン/Tie-2 経路を介して特発性肺線維症における血管新生を調節する
[PDF] MicroRNA-124-3p alleviates repetitive bleomycin induced idiopathic pulmonary fibrosis in mouse by repressing Wnt/β-catenin signaling component AXIN1
D Jaggi, K Aggarwal, L Goyal - STEMedicine, 2023
… of idiopathic pulmonary fibrosis (IPF). Methods: Mouse IPF model was established using repetitive intratracheal bleomycin (BLM) dosing, … Repetitive intratracheal bleomycin models several features of idiopathicpulmonary fibrosis. Am …
- マイクロRNA-124-3pは、Wnt/β-カテニンシグナル伝達成分AXIN1を抑制することにより、マウスのブレオマイシン誘発性特発性肺線維症の反復性を軽減します。
[PDF] The causal effects of lipids and apolipoproteins on idiopathic pulmonary fibrosis: A Mendelian randomization study
YJ Qi, J ZHAO, Q Lyu, J Zhang, WL Zhu - 2023
… idiopathic pulmonary brosis (IPF) in some studies, but this has not been con rmed from a genetic perspective. Our aim was to assess the causal effect of lipid and apolipoprotein levels on IPF … between lipid and apolipoprotein levels and IPF …
- 特発性肺線維症に対する脂質とアポリポタンパク質の因果関係: メンデルランダム化研究
[PDF] Baricitinib improves the efficacy of nintedanib for the treatment of idiopathic pulmonary fibrosis
Q Wan, D Li, S Shang, H Wu, F Chen, Q Li - 2023
Background: Nintedanib has been approved to treat idiopathic pulmonary fibrosis (IPF) but with limited efficacy, while targeting Janus Kinases (JAK)/Transducer and signal activator of transcription (STAT) has emerged as a feasible strategy in this disease …
- バリシチニブは、特発性肺線維症の治療におけるニンテダニブの有効性を改善します
[HTML] Low Daily Step Count Associated with Small Erector Spine Muscle Area and Sarcopenia in Idiopathic Pulmonary Fibrosis
H Ohkubo, K Fujita, K Ito, A Nakano, M Horiuchi, Y Mori… - Internal Medicine, 2024
… idiopathic pulmonary fibrosis (IPF). However, the factors associated with this phenomenon are not yet fully understood. We therefore clarified its association with clinical parameters. Methods Fifty-nine patients with IPF… in idiopathic pulmonary …
- 特発性肺線維症における脊柱起立筋の面積が小さいこととサルコペニアに関連する一日の歩数の少なさ
[PDF] Machine Learning-Based Integration Identifies Plasma Cells-Related Gene Signature ST6GAL1 in Idiopathic Pulmonary Fibrosis and Its Pan-Cancer Analysis
F Lin, K Lin, DL Li, W Kong, X Wei, W He, T Xiao, H Zu… - 2023
… effector cell in IPF development and progression. The aim of this study is to identify biomarkers associated with plasma cells in IPFand initially … The ndings of this study are expected to help improve the clinical outcomes of IPF patients and …
Risk Factors Of Idiopathic Pulmonary Fibrosis In Pakistani Population: A Matched Case-Control Studyy.
SZ AB, U Rabbani, M Hassan, Z Fatmi, N Ahmed… - JPMA. The Journal of the …, 2023
… Subjects without idiopathic pulmonaryfibrosis but registered with the department of pulmonology of the two hospitalswere enrolledas controls. Datawas collectedusinga structuredquestionnaire, andanthropometricmeasurements were …
- パキスタン人集団における特発性肺線維症の危険因子:対照症例対照研究。
[PDF] From purpura to idiopathic purpura fulminans: a guidance in diagnosis and therapy
L De Cloedt, I Vanholder, C Arkaz, C Lafaire… - Belgian Journal of …, 2023
… can occur, varicella-associated idiopathicpurpura fulminans being one of them. Purpura … to be the cause of this form of PF, called idiopathic PF (IPF) (1-3). Early clinical recognition … We present a case of a previously healthy two-year-old girl …
- 紫斑病から特発性劇症紫斑病まで:診断と治療の指針
<><><>
特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
###