AIとIPFと癒しの音楽

特発性肺線維症 idiopathic pulmonary fibrosis (IPF)患者によるIPF関連学術情報の収集とシェア。癒しの音楽もお届けしています。

IPF Weekly Update

ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です!と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この1年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。

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24/01/25

 

[HTML] SGK1 aggravates idiopathic pulmonary fibrosis by triggering H3k27ac-mediated macrophage reprogramming and disturbing immune homeostasis

J Wu, L Gong, Y Li, T Liu, R Sun, K Jia, R Liu, F Dong… - International Journal of …, 2024

Idiopathic pulmonary fibrosis (IPF) is characterized by fibrotic matrix deposition and irreversible aberrant tissue remodeling. Their mechanisms of action are associated with the activation of macrophages and a disturbed immune environment. We aim to …

  • SGK1は、H3k27acを介したマクロファージの再プログラミングを引き起こし、免疫恒常性を妨害することにより、特発性肺線維症を悪化させる




[HTML] The Impact of Chronic Comorbidities on Outcomes in Acute Exacerbations of Idiopathic Pulmonary Fibrosis

SH Baig, EJ Yoo - Life, 2024

… : Idiopathic pulmonary fibrosis is a … of idiopathic pulmonary fibrosis (AE-IPF). Methods: This was a retrospective cohort study using the NIS database from 2016 to 2018. We included patients aged 60 and older hospitalized in academic medical …

  • 特発性肺線維症の急性増悪における転帰に対する慢性併存疾患の影響




Brg1/PRMT5 Nuclear Complex Epigenetically Regulates FOXO1 In IPF Mesenchymal Progenitor Cells

AH Jbeli, L Yang, H Xia, AJ Gilbertsen, PB Bitterman… - American Journal of …, 2024

… Epidemiology and survival of idiopathic 372 pulmonary fibrosis from national data in Canada. … A phase 3 trial of pirfenidone in patients with 395 idiopathic pulmonaryfibrosis. N Engl J … idiopathic pulmonaryfibrosis. The Journal of Clinical …

  • Brg1/PRMT5核複合体はIPF間葉前駆細胞のFOXO1をエピジェネティックに制御する




[HTML] New Insights in the Pathology of Chronic Thromboembolic Pulmonary Hypertension

S Sharma, S Antoniak - Basic to Translational Science, 2024

… pulmonary arterial hypertension (PAH) and patients with idiopathic pulmonary fibrosis(IPF) compared with healthy control subjects. This suggests … Interestingly, only TGFBI and STC2 protein expression were up-regulated in CTEPH compared …

  • 慢性血栓塞栓性肺高血圧症の病理学における新たな洞察



24/01/23

 

[HTML] A formula for predicting emphysema extent in combined idiopathic pulmonary fibrosis and emphysema

AU Wells, J Jacob, N Sverzellati, G Cross, J Barnett… - Respiratory Research, 2024

… of emphysema in idiopathic pulmonaryfibrosis (IPF). Without experienced radiologists, other methods are needed to determine emphysema extent. Here, we report the development and validation of a formula to predict emphysema extent in …

  • 特発性肺線維症と肺気腫を合併した場合の肺気腫の程度を予測する式




A novel model for predicting prognosis in patients with idiopathic pulmonary fibrosis based on endoplasmic reticulum stress‐related genes

B Liu, X Zhang, Z Liu, H Pan, H Yang, Q Wu, Y Lv… - Cell Biology International, 2024

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic disease of unknown pathogenic … was involved in the evolution and progression of IPF. In this study, we obtained transcriptome … Our results suggested that ERSRGs might play a critical …

  • 小胞体ストレス関連遺伝子に基づく特発性肺線維症患者の予後予測のための新しいモデル




Inhaled nanoparticles for treating idiopathic pulmonary fibrosis by inhibiting honeycomb cyst and alveoli interstitium remodeling

MM Han, L Tang, B Huang, XN Li, YF Fang, L Qi… - Journal of Controlled …, 2024

Idiopathic pulmonary fibrosis (IPF) is a lethal … IPF could be alleviated by repairing injured AEC II, inhibiting fibroblast overactivation and regulating dysregulated immune cells [[12], [13], [14], [15], [16], [17]]. However, with the further …

  • ハニカム嚢胞および肺胞間質のリモデリングを阻害することにより、特発性肺線維症を治療するための吸入ナノ粒子




Reply: Telomere length and immunosuppression in non-idiopathic pulmonary fibrosis interstitial lung disease

D Zhang, A Adegunsoye, JM Oldham, PJ Wolters… - European Respiratory …, 2024

… -idiopathic pulmonary fibrosis interstitial lung disease (ILD) patients [1]. Our findings suggest that shared genetic vulnerability to pulmonary fibrosis … diagnostic labels experience progression akin to idiopathicpulmonary fibrosis (IPF) [2, 3] …

  • 非特発性肺線維症間質性肺疾患におけるテロメア長と免疫抑制




Telomere length and immunosuppression in non-idiopathic pulmonary fibrosis interstitial lung disease

JA Mackintosh, DC Chambers - European Respiratory Journal, 2024

… , mirroring the authors’ previous post hoc analysis of the PANTHER-IPF data [2]. However, as in previous manuscripts [3, 4], the authors … Telomere length and use of immunosuppressive medications in idiopathic pulmonary fibrosis. Am J Respir …

  • 非特発性肺線維症間質性肺疾患におけるテロメア長と免疫抑制




Central processes and cough in idiopathic pulmonary fibrosis

K Hett - 2023

… Three studies have been performed to advance our understanding of the central processes involved in cough and IPF and lay a … in 17 patients with IPF and 16 matched controls. A cross-sectional questionnaire study was conducted in 120 …

  • 特発性肺線維症の中枢過程と咳




ErbB4 promotes M2 activation of macrophages in idiopathic pulmonary fibrosis

J Yu, S Jialin, Z Junhao, H Chunxiao, G Ruinan - Open Life Sciences, 2023

Idiopathic pulmonary fibrosis (IPF) is the most common and fatal diffuse fibrotic lung disease … members were increased in the serum of IPF patients. In mouse alveolar macrophage MH-S … Collectively, our data support that ErbB4 and M2 …

  • ErbB4 は特発性肺線維症におけるマクロファージの M2 活性化を促進




Risk factors for progression of pulmonary fibrosis: a single-centered, retrospective study

J Gu, S Xiao, M Jia, G Han - Frontiers in Medicine

… associated with the prevalence of progressive pulmonary fibrosis (PPF) in interstitial … -idiopathic pulmonary fibrosis idiopathicinterstitial pneumonia (non-IPF IIP), and 35 (11.4%) had hypersensitivity pneumonitis (HP). Overall, 118 (38.4%) …

  • 肺線維症進行の危険因子:単一施設の後ろ向き研究




Hospitalization Rates in Interstitial Lung Disease: An Analysis of the Pulmonary Fibrosis Foundation Registry

CS King, RV Ignacio, V Khangoora, A Nyquist… - American Journal of …, 2024

… -related interstitial lung disease and non-idiopathic pulmonary fibrosis idiopathicinterstitial pneumonias had higher transplant-free survival … how these events might be better leveraged in future clinical trials in both idiopathic pulmonary fibrosis

  • 間質性肺疾患の入院率: 肺線維症財団登録簿の分析




[HTML] The SIRT1/Nrf2 signaling pathway mediates the anti-pulmonary fibrosis effect of liquiritigenin

Q Hua, L Ren - Chinese Medicine, 2024

idiopathic pulmonary fibrosis are both limited and often come with severe side effects, emphasizing the pressing requirement for innovative therapeutic alternatives. Myofibroblasts, which hold a central role in pulmonary fibrosis… bleomycin-induced …

  • SIRT1/Nrf2 シグナル伝達経路はリキリチゲニンの抗肺線維症効果を媒介



 

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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。

当面、毎週アラートの内容をアップしていこうと思います。

 

癒しの音楽をお届けいたします。 

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