ChatGPTなどを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です！と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。
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25/01/03
Biomimetic Topological Micropattern Arrays Regulate the Heterogeneity of Cellular Fates in Lung Fibroblasts between Fibrosis and Invasion
X Zhu, S Mao, Y Yang, X Liu, Q Liu, N Zhang, Y Yang… - ACS Nano, 2025
… Idiopathic pulmonary fibrosis (IPF) is characterized by persistent tissue injury, dysregulated wound healing, and extracellular matrix (ECM) deposition by myofibroblasts (MFs) through the fibroblast-to-myofibroblast transition (FMT). Implicit …
- 生体模倣トポロジカルマイクロパターンアレイは、肺線維芽細胞における線維化と浸潤の間の細胞運命の不均一性を制御する
25/01/02
Serum cholesterol levels predict the survival in patients with idiopathic pulmonary fibrosis: A long-term follow up study
R Chen, G Zhong, T Ji, Q Xu, H Liu, Q Xu, L Chen… - Respiratory Medicine, 2024
… idiopathic pulmonary fibrosis (IPF) required to be explored. We aim to evaluate the association of serum lipid levels with mortality in patients with IPF… This study demonstrated that lower TC levels were associated with increased mortality in IPF …
- 血清コレステロール値は特発性肺線維症患者の生存を予測する：長期追跡調査
Effect of idiopathic pulmonary fibrosis on postoperative prognosis of patients with non-small cell lung cancer
LI Na, LI Xiaoli, LI Jing, J Wang - Chinese Journal of Clinical Medicine, 2024
… Abstract: Objective To investigate the effect of idiopathic pulmonary fibrosis (IPF) on the prognosis of patients with non-small cell lung … 2019 were selected, and were divided into the IPF group and the non-IPF group. The clinicpathological and …
- 特発性肺線維症が非小細胞肺癌患者の術後予後に及ぼす影響
Elucidating the causal associations and mechanisms between circulating immune cells and idiopathic pulmonary fibrosis: New insights from Mendelian randomization …
H Yang, X Wu, X Xiao, J Chen, X Yu, W Zhao, F Wang - Frontiers in Immunology
… an association between circulating immune cell phenotypes and idiopathic pulmonaryfibrosis (IPF). Although studies have attempted to … cells and IPF and to explore potential biomarkers. Methods: We first explored the bidirectional causal …
Investigation of the Electrochemical Behavior of the Drug Active Ingredient Pirfenidone and Its Analytical Application in Natural Samples
N Kökener, B Tunay, E Demir, NA Ozdogan, M Mısır - International Bulletin of …, 2024
… Pirfenidone is an active pharmaceutical ingredient used orally in the treatment of idiopathic pulmonary fibrosis and possesses antifibrotic, … , stabilizes lung function, and reduces the number of acute exacerbations in IPF patients. However, the drug is …
- 薬物有効成分ピルフェニドンの電気化学的挙動の調査と天然サンプルにおけるその分析への応用
[HTML] Peripheral nerve stimulation can reduce tremor symptoms
J Smith
LOS ANGELES–A noninvasive peripheral nerve stimulation device has been shown to reduce symptoms of hand tremor among people with essential tremor, offering a possible alternative to invasive treatments such as deep-brain stimulation. The …
- 末梢神経刺激は振戦症状を軽減できる
25/01/01
Discovery of novel capsaicin analogs as TRPV1 inhibitors for the treatment of idiopathic pulmonary fibrosis
Y Cao, Y Wen, Z Zhou, R Xi, W Shuai, J Zhang… - European Journal of …, 2024
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease for which few drugs are available in clinical practice. Here, we identified novel capsaicin analogs by combining in-house chemical library screening and further …
- 特発性肺線維症の治療のためのTRPV1阻害剤としての新しいカプサイシン類似体の発見
[HTML] ANTI-PL-7/PL-12 ANTISYNTHETASE SYNDROME ASSOCIATED WITH INTERSTITIAL LUNG DISEASE FOLLOWING SARS-COV-2 INFECTION AND VACCINATION …
L García-Bravo, Á Villegas, B López, A Mariscal… - Heliyon, 2024
Cumulative evidence suggests a link between specific autoimmune diseases (AD), including idiopathic inflammatory myopathies (IIM), and SARS-CoV-2 infection or COVID-19 vaccination. Anti-synthetase syndrome (ASS), a subset of IIM, is defined …
24/12/30
[HTML] The density histograms-derived computerized integrated index (CII) predicts mortality in idiopathic pulmonary fibrosis
G Rea, R Lieto, D Bruzzese, PR Iovine, A Mazzocca… - Scientific Reports, 2024
… Idiopathic pulmonary fibrosis (IPF) remains the most aggressive form among interstitial lung … The prognosis of patients affected by IPF is severe with a median survival of 3–5 years in … The radiological assessment of the IPF patient represents …
- 密度ヒストグラムから導かれるコンピュータ統合指数（CII）は特発性肺線維症の死亡率を予測する
[HTML] Inhalable Carbonyl Sulfide Donor-Hybridized Selective Phosphodiesterase 10A Inhibitor for Treating Idiopathic Pulmonary Fibrosis by Inhibiting Tumor Growth Factor …
Q Wang, X Liu, H Yuan, F Zhang, J Wu, D Yang, J Qian… - ACS Pharmacology & …, 2024
Idiopathic pulmonary fibrosis (IPF) is a debilitating, incurable, and life-threatening disease that lacks effective therapy. The overexpression of phosphodiesterase 10A (PDE10A) plays a vital role in pulmonaryfibrosis (PF). However, the impact of selective …
- 腫瘍増殖因子を阻害することで特発性肺線維症を治療するための吸入可能な硫化カルボニル供与体ハイブリダイゼーション選択的ホスホジエステラーゼ 10A 阻害剤
Effect of CTMP1 gene on pulmonary fibrosis
H Nguyen, U Juang, S Gwon, W Jung, Q Huang, S Lee… - Toxicological Research, 2024
… Idiopathic pulmonary fibrosis (IPF) is an irreversible, chronic, progressive pulmonary disorder; the clinical treatment options are limited. Of the various experimental models, bleomycin-induced lung fibrosis is the most extensively …
- CTMP1遺伝子の肺線維症への影響
[PDF] Prevalence of Gastroesophageal Reflux in Interstitial Lung Diseases Clinic
N Akhter, KK Sumalani, D Chawla, N Rizvi, K Khan - Cureus, 2024
… to find the association of GERD with idiopathic pulmonary fibrosis (IPF) only. The aim of this … The etiology of idiopathicpulmonary fibrosis (IPF) remains unclear, while many other ILDs … Gastroesophageal reflux disease (GERD) has been linked …
- 間質性肺疾患クリニックにおける胃食道逆流症の有病率
[PDF] Innovations in Respiratory Therapy: Addressing Pulmonary Fibrosis with Inhalation Techniques
AS Albalawi, FS Alharbi, GH Alanazi, ABM Alabbad… - Journal of International …, 2024
… Pulmonary fibrosis (PF) is a debilitating condition with increasing incidence worldwide. Idiopathic pulmonary fibrosis (IPF) is the most common form of PF, characterized by progressive lung scarring and declining lung function. Current oral …
- 呼吸療法の革新：吸入技術による肺線維症への対処
[HTML] Obesity affects the ability to diagnose liver fibrosis
I Lacy
… idiopathic pulmonary fibrosis (IPF) by a private physician and started pirfenidone and oxygen therapy. Three months later the patient presented to the VA Caribbean Healthcare System in San Juan Puerto Rico when he developed an exacerbation of …
- 肥満は肝線維症の診断能力に影響を与える
24/12/29
[PDF] An important radiological clue in idiopathic pulmonary fibrosis: Diffuse pulmonary ossification
H Alper - Tuberk Toraks, 2024
… idiopathic pulmonary fibrosis (IPF) has been shown in the literature. We examined DPO, which is the supporting computed tomography (CT) finding of IPF… Idiopathic pulmonaryfibrosis (IPF) represents a clinical disease characterized by the …
- 特発性肺線維症における重要な放射線学的手がかり：びまん性肺骨化
Adaptive Chest Cavity Expansion Following Lung Allograft Oversizing in Idiopathic Pulmonary Fibrosis
DA Gouchoe, MM Botros, D Satija, SH Roberts… - Journal of Surgical …, 2025
… matching for patients with idiopathicpulmonary fibrosis (IPF) are lacking, and the question remains whether or not the IPF recipient chest can … and pulmonary function in recipients with IPF. We hypothesized that oversized allografts (OAs) could …
- 特発性肺線維症における肺移植後の適応性胸腔拡張
[HTML] Endothelial CD38-induced endothelial-to-mesenchymal transition is a pivotal driver in pulmonary fibrosis
M Hu, XH Guan, LF Wang, HM Xu, SF Ke, QY Yuan… - Cellular and Molecular Life …, 2025
… Obviously, our data should provide new insights in elucidation the role and underlying mechanism of CD38 in idiopathic pulmonaryfibrosis (IPF), suggesting that endothelial CD38 may be a potential therapeutic target for preventing and …
- 内皮CD38誘導による内皮間葉転換は肺線維症の重要な原因である
Wogonin Attenuates Bleomycin-Induced Pulmonary Fibrosis and Oxidative Stress Injury via the MAPK Signaling Pathway
B Bian, C Ge, F Wu, Y Fan, J Kong, K Li, H Bian… - … and Pharmaceutical Bulletin, 2024
… Idiopathic pulmonary fibrosis (PF) is an irreversible and chronic inflammatory condition with limited therapeutic options and a high mortality rate. We aimed to determine the possible role and mechanisms of wogonin (WGN) on PF. A rat model …
- ウォゴニンはMAPKシグナル経路を介してブレオマイシン誘発性肺線維症および酸化ストレス障害を軽減する
24/12/28
Machine Learning Potential Predictor of Idiopathic Pulmonary Fibrosis
C Ding, L Qiao, R Zuo, Z Shichao, Z Guo, Z Ye, J He… - Frontiers in Genetics
… Idiopathic pulmonary fibrosis (IPF) is a severe chronic respiratory disease characterized by … In this study, we obtained gene expression profiles and corresponding clinical data of IPF … This study highlights their potential for early …
MSR111 Using Patient-Level Simulation to Estimate Long-Term Survival in Idiopathic Pulmonary Fibrosis
K Johannesen, W Herring, P Chopra, B Elpers, O Dong - Value in Health, 2024
… Idiopathic pulmonary fibrosis (IPF) is a chronic and debilitating disease with poor long-term prognosis and survival. When assessing the long-term effectiveness and cost-effectiveness of IPF … IPF using patient-level simulation based on IPF-specific …
- MSR111 患者レベルのシミュレーションを用いた特発性肺線維症の長期生存の推定
RWD67 Practice Gaps and Variations in the Pharmacological Management of Interstitial Lung Disease (ILD): Real-World Insights From the AccessILD Registry in the …
O Efthymiadou, YH Chang, A Jina, P Molyneaux… - Value in Health, 2024
… completed the ePRO survey; 36% have Idiopathic Pulmonary Fibrosis (IPF) and 64% have non-IPF ILD, including “systemic disease with … while 7% of IPF patients report concomitant use of corticosteroid and antifibrotic therapy. Antifibrotics are …
- RWD67 間質性肺疾患（ILD）の薬理学的管理における実践のギャップとばらつき：英国の AccessILD レジストリからの実際の洞察
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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
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