ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です！と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この１年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。
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24/08/24
[PDF] Enzyme-like nanoparticle–engineered mesenchymal stem cell secreting HGF promotes visualized therapy for idiopathic pulmonary fibrosis in vivo
H Bao, M Wu, J Xing, Z Li, Y Zhang, A Wu, J Li - Science Advances, 2024
… Stem cell therapy is being explored as a potential treatment for idiopathic pulmonaryfibrosis (IPF), but its effectiveness is hindered by … biological behavior in IPF mice in vivo. Overall, this study provides an efficient and forward-looking …
- 酵素様ナノ粒子で設計されたHGF分泌間葉系幹細胞は、生体内での特発性肺線維症の可視化治療を促進する
[HTML] Evaluation of progressive pulmonary fibrosis in non-idiopathic pulmonary fibrosis-interstitial lung diseases: a cross-sectional study
Ö Erçen Diken, Ö Güngör, H Akkaya - BMC Pulmonary Medicine, 2024
… Three categories exist for ILD that progress to fibrosis: idiopathic interstitial fibrosis (IPF), non-IPF ILD, and unclassifiable ILD. While IPF is the most well-known and well-recognized group of ILDs associated with fibrosis development, non-IPF …
- 非特発性肺線維症-間質性肺疾患における進行性肺線維症の評価：横断的研究
[PDF] Evaluation of progressive pulmonary fibrosis in non-idiopathic pulmonary fibrosis-interstitial lung diseases: a cross-sectional study
ÖE Diken, Ö Güngör, H Akkaya - 2024
… Three categories exist for ILD that progress to fibrosis: idiopathic interstitial fibrosis (IPF), nonIPF ILD, and unclassifiable ILD. While IPF is the most well-known and well-recognized group of ILDs associated with fibrosis development, non-IPF …
- 非特発性肺線維症-間質性肺疾患における進行性肺線維症の評価：横断的研究
Affinity of Nintedanib Towards New Candidate Target for Idiopathic Pulmonary Fibrosis
HB Balasubramanian, S Biswas, M Talmon, F Patrucco… - Borneo Journal of Pharmacy, 2024
… Idiopathic pulmonary fibrosis (IPF) is a progressive disease due to aggregation of fibroblasts on lung parenchyma. Nintedanib, an indolinone-derived tyrosine kinase inhibitor (TKi) has been approved for the treatment of IPF … protein candidates for …
- 特発性肺線維症の新たな候補ターゲットに対するニンテダニブの親和性
Correction: Identification and validation of targets of swertiamarin on idiopathic pulmonary fibrosis through bioinformatics and molecular docking-based approach
J Chang, S Zou, Y Xiao, D Zhu - BMC Complementary Medicine and Therapies, 2024
A correction has been made to Fig. 5. The sub-image of GAPDH (the last western blot image of Fig. 5 A) was replicated and incorrectly uploaded instead of the sub-image for COL5A2 (the first line of the Fig. 5 A). This error does not affect the conclusion of …
- 訂正：バイオインフォマティクスと分子ドッキングに基づくアプローチによる特発性肺線維症に対するスウェルチアマリンの標的の特定と検証
Bronchoalveolar Lavage Fluid Cellular Analysis and Radiologic Patterns in Patients with Fibrotic Interstitial Lung Disease
A Grant-Orser, M Asmussen, DC Marinescu, CJ Hague… - CHEST
… evaluation and enrolled in the prospective Canadian Registry for Pulmonary Fibrosis were re-reviewed in a standardized multidisciplinary … Radiologists classified HRCTs according to guideline-defined patterns for idiopathicpulmonary …
- 線維性間質性肺疾患患者の気管支肺胞洗浄液細胞分析と放射線学的パターン
[PDF] Potential of phosphodiesterase 4B inhibitors in the treatment of interstitial lung disease associated with autoimmune diseases
FV Castelino, A Adegunsoye
… In a phase II trial in patients with idiopathicpulmonary fibrosis, nerandomilast (given alone or on top of background antifibrotic therapy) prevented a decrease in lung function over 12 weeks with an acceptable safety and tolerability profile. The phase …
- 自己免疫疾患に関連する間質性肺疾患の治療におけるホスホジエステラーゼ4B阻害剤の可能性
24/08/23
EGR1 interacts with p-SMAD at the endothelin-1 gene promoter to regulate gene expression in TGFβ1-stimulated IMR-90 fibroblasts
TY Kim, H Yeo, E Jung, SY Shin - Biochemical and Biophysical Research …, 2024
… pulmonary fibrosis induced by intratracheal administration of bleomycin. These findings suggest that targeting EGR1 is a promising approach for treating pulmonary fibrosis, especially idiopathic pulmonary fibrosis… Idiopathic pulmonary fibrosis (IPF) …
- EGR1はエンドセリン1遺伝子プロモーターでp-SMADと相互作用し、TGFβ1刺激を受けたIMR-90線維芽細胞における遺伝子発現を制御する。
[PDF] Interstitial lung diseases with concomitant lung cancer: a data mining approach revealing a complex condition with gender and immune-associated specific …
F Perrotta, D Lacedonia, V D'Agnano, A Bianco… - 2024
… Global incidence and mortality of idiopathicpulmonary fibrosis: a systematic review. Eur … Idiopathic pulmonary fibrosis: a disease with similarities and links to cancer biology. Eur … Autoantibodies are associated with disease progression in …
- 肺癌を併発する間質性肺疾患：性別と免疫関連の特異的な意味合いを持つ複雑な病態を明らかにするデータマイニングアプローチ
[HTML] RIOK2 transcriptionally regulates TRiC and dyskerin complexes to prevent telomere shortening
S Ghosh, MT Nguyen, HE Choi, M Stahl, AL Kühn… - Nature Communications, 2024
… Syndromes (MDS) and IdiopathicPulmonary Fibrosis (IPF). Optimal telomerase activity … and IPF patients, and it strongly correlates with shortened telomeres in MDS patient-derived bone marrow cells. Importantly, ectopic expression of RIOK2 …
- RIOK2はTRiCとジスケリン複合体の転写を制御してテロメアの短縮を防ぐ
[HTML] Value of bronchoalveolar lavage fluid metagenomic next-generation sequencing in acute exacerbation of fibrosing interstitial lung disease: an individualized treatment …
S Zhan, S Li, Y Cao, D Liu, J Feng - BMC Pulmonary Medicine, 2024
… We defined AE-ILD with the same clinical criteria as AE-IPF, and including both triggered and idiopathic AE-ILDs. The included patients … Unclassifiable idiopathic interstitial pneumonia (uIIP), acute interstitial pneumonia (AIP), and idiopathic …
Study on the impact of Toll-like Receptor 4 (TLR4) modulation in rare inflammatory-fibrotic diseases
A Italia, A Franco, M Shaik, A Romerio, F Lami… - 2024
… Here it is proposed an in vitro screening on cellular models of fibrosis with TLR4 antagonists to identify new potential drugs targeting Idiopathic Pulmonary Fibrosis (IPF), a rare fibrotic pathology where a pivotal role of TLR4-mediated inflammation has …
- 希少炎症性線維性疾患におけるToll様受容体4（TLR4）調節の影響に関する研究
The Lymphatic Highway: How Lymphatics Drive Lung Health and Disease
X Zhang, X Du, Y Cui - Lung, 2024
… We highlight common pathological changes in lung lymphatics that actively drive disease progression in chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis(IPF), asthma, and lung transplant rejection. We also explore …
- リンパハイウェイ: リンパが肺の健康と病気に及ぼす影響
24/08/22
[PDF] Research progress on interferon and cellular senescence
D Wang, K Chen, Z Wang, H Wu, Y Li - The FASEB Journal, 2024
… Firstly, the comparison in tissues from idiopathic pulmonary fibrosis and … idiopathic pulmonary fibrosis, whereas I- IFN signaling showed an upregulation in populations with interstitial lung disease, and alveolar type I cells significantly …
- インターフェロンと細胞老化に関する研究の進歩
24/08/20
[PDF] Significance of Systemic Scleroderma-Specific Autoantibodies in Idiopathic Interstitial Pneumonia
Y Murakami, H Wakabayashi, K Kaneko, K Takashima… - Cureus, 2024
… in IPF have been identified as age, male sex, lower predicted FVC, extensive ground-glass shadows or fibrosis lesions in HRCT, and malignancy. Risk factors for AE in IPF … The results in this study were similar to those for death and risk factors …
- 特発性間質性肺炎における全身性強皮症特異的自己抗体の重要性
NLRP3 inflammasome activation contributes to the development of the pro-fibrotic phenotype of lung fibroblasts
TH Nguyen, TD Nguyen, VTH Tran, HA Nguyen… - Biochemical Pharmacology, 2024
… Idiopathic pulmonary fibrosis (IPF) is an irreversible progressive interstitial lung disease of unknown cause. The poorly understood pathophysiology of IPF … increased in lung fibroblasts derived from individuals with pulmonary fibrosis and in …
- NLRP3インフラマソームの活性化は肺線維芽細胞の線維化促進表現型の発達に寄与する
24/08/19
[HTML] Higher body mass index was associated with a lower mortality of idiopathic pulmonary fibrosis: a meta-analysis
D Pan, Q Wang, B Yan, X Su - Journal of Health, Population and Nutrition, 2024
… a notable rise in the incidence and prevalence of idiopathic pulmonary fibrosis (IPF) on a global scale. A … IPF patients remains underexplored in the existing literature. We aim to shed light on this relationship and potentially offer novel insights into …
- 体格指数が高いほど特発性肺線維症の死亡率が低いことがメタ分析で判明
Correlations between blood vessel distribution, lung function and structural change in idiopathic pulmonary fibrosis
PW Hu, CK Chen, YH Hsiao, CY Weng, YC Lee, KC Su… - Respirology (Carlton, Vic.)
… with idiopathic pulmonary fibrosis (IPF) remain unclear. This study aimed to investigate the impacts of pulmonary blood-vessel distribution and the extent of fibrosis on the lung function and quality of life of patients with IPF. Methods: Patients …
- 特発性肺線維症における血管分布、肺機能および構造変化の相関関係
[PDF] The Prognostic Role of Advanced Lung Inflammation Index in Patients with Idiopathic Pulmonary FibrosisFibrosis
F Bozkuş, O Keskin - 2024
… Idiopathic Pulmonary Fibrosis (IPF) is a chronic and progressive lung disease characterized by irreversible deterioration of lung function and a short median survival time. It is associated with an age-standardized mortality rate ranging from …
- 特発性肺線維症患者における進行性肺炎症指数の予後予測における役割
[PDF] Mount Sinai Respiratory Institute Presents: Advances in Pulmonary Medicine 2024
M Kraft - 2024
… A keynote speaker will deliver a state-of-the-art lecture on current and future perspectives of idiopathic pulmonary fibrosis. To enhance practical skills, there will be workshops focusing on patient access, point-of-care diagnostics for sleep apnea …
- マウントサイナイ呼吸器研究所が発表: 2024 年の呼吸器医学の進歩
24/08/18
Imaging Approach to Pulmonary Hypertension
S Sridhar, S Ebrahimzadeh, H Ahn, C Lee, J Liu - Radiologic Clinics, 2024
… Restrictive lung disease such as pulmonaryfibrosis can cause coarse reticular opacities, traction … Pulmonary fibrosis may be detected on CT performed as part of the evaluation for PH. … is present in a greater proportion of patients who have …
- 肺高血圧症に対する画像診断アプローチ
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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
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