ChatGPTを活用して業務のAI化を進めています。プロンプトエンジニアリングの専門家です！と、名乗れるレベルではありませんが、かなり色々使いこなしてきています。この１年、病気で失われた能力は、別な能力を発達させる、進化することで生き残っていこうと思います。
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24/03/30
Epidemiology and Prognostic Significance of Cough in Fibrotic Interstitial Lung Disease
YH Khor, KA Johannson, V Marcoux, JH Fisher… - American Journal of …, 2024
… persists and worsens over time in patients with idiopathic pulmonary fibrosis (IPF) and nonIPF fibrotic ILD irrespective of ILD-targeted therapy. … Methods: We included consecutive patients with idiopathic pulmonary fibrosis(IPF) and non-IPF …
- 線維性間質性肺疾患における咳の疫学と予後的意義
Interstitial lung disease: A review of classification, aetiology, epidemiology, clinical diagnosis, pharmacological and non-pharmacological treatment
MA Althobiani, AM Russell, J Jacob, Y Ranjan… - Frontiers in Medicine
… Idiopathic Pulmonary Fibrosis is the most aggressive form of ILD, causing progressive and permanent lung scarring. It causes a chronic and irreversible lung disease with a poor prognostic outcome with a median survival rate of 3-5 years post-diagnosis …
Imaging of the Spectrum of Acute Lung Injury
S Kligerman - Clinics in Chest Medicine, 2024
… patient morbidity and mortality as survivors of ALI can be left with severe and debilitating pulmonary fibrosis. In this article, the spectrum of radiologic findings with a brief discussion … However, this merely denotes that the cause has missed …
- 急性肺損傷のスペクトルの画像化
24/03/28
Inhaled nintedanib nanoparticles for enhanced efficacy in idiopathic pulmonary fibrosis (IPF) treatment–Evidence in disease-relevant in-vitro models
X Wang, M Goyal, D Gadhave, V Gupta - Journal of Drug Delivery Science and …, 2024
… Idiopathic pulmonary fibrosis (IPF) is a fatal and progressive interstitial lung disease with a high mortality rate due to limited … , idiopathicpulmonary fibrosis (IPF) stands as the prevailing and most severe form of PF with a median life expectancy of …
- 特発性肺線維症（IPF）治療における有効性を高める吸入ニンテダニブナノ粒子 – 疾患関連の in vitro モデルでの証拠
[HTML] Acute exacerbation of idiopathic pulmonary fibrosis disease: a diagnosis model in China
L Meng, J Xiao, L Wang, Z Huang - European Journal of Medical Research, 2024
… Idiopathic pulmonary fibrosis (IPF) is the most common of the idiopathic interstitial pneumonias, … For patients with AE-IPF, it would be beneficial to predict the likelihood of clinically significant … significant idiopathicpulmonary fibrosis patients …
- 特発性肺線維症疾患の急性増悪：中国の診断モデル
Identification of non-coding RNA signatures in idiopathic pulmonary fibrosis
A Elek, E Bozgeyik, H Caska, Z Gocer, I Bozgeyik - Irish Journal of Medical Science …, 2024
… with IPF. An evident characteristic of IPF is the development of fibroblastic foci representing active fibrotic areas. Most of the cells within these foci are believed to be myofibroblasts, which are thought to be the primary source of abnormal …
microRNA-Based Approaches Targeting Alveolar Epithelial Cells as Pro-Regenerative Treatment in Idiopathic Pulmonary Fibrosis
MC Volpe - 2024
… In idiopathic pulmonary fibrosis (IPF) ATIIs are damaged and therefore cannot trans-differentiate ATIs, contributing to the progressive lung function damage. Available treatments for IPF patients, Nintedanib and Pirfenidone only reduce the …
- 特発性肺線維症における再生促進治療として肺胞上皮細胞を標的とするマイクロRNAベースのアプローチ
[PDF] The Correlation Between Idiopathic Pulmonary Fibrosis and Lung Cancer
Y Liu - Transactions on Materials, Biotechnology and Life …, 2024
… condition known as idiopathic pulmonaryfibrosis (IPF) is defined with the repeated scarring of pulmonary tissues. About 3 million individuals are impacted globally, and that figure is only increasing. There are no effective treatments …
- 特発性肺線維症と肺がんの相関関係
Dissecting the role of microRNAs and cellular aging in the pathophysiology of Idiopathic Pulmonary Fibrosis
G Zandomenego - 2024
… Idiopathic pulmonary fibrosis is an interstitial lung disease, characterized by a progressive … To elucidate aging processes and miRNAs involved in the IPF’s pathogenesis, we performed a … Accordingly, both miRNAs scored upregulated in …
- 特発性肺線維症の病態生理学におけるマイクロRNAと細胞老化の役割を詳しく分析する
Novel SASP factor mediates fibroblast reprogramming in aging-associated pulmonary fibrosis
MCM Narvaez, E Jain, T Suciu, S Asgharpour, Q Hu… - 2024
… and impaired regeneration found in idiopathicpulmonary fibrosis (IPF). However, molecular … Moreover, IPF lungs showed a significant increase in senescent cells (P16+) co-expressing … senescence-associated lung fibrosis as a potential therapeutical …
- 新規SASP因子は加齢に伴う肺線維症における線維芽細胞の再プログラミングを媒介
[HTML] Kefir peptides mitigate bleomycin-induced pulmonary fibrosis in mice through modulating oxidative stress, inflammation and gut microbiota
YW Lan, YC Chen, CC Yen, HL Chen, MC Tung… - Biomedicine & …, 2024
… Idiopathic pulmonary fibrosis (IPF) is a progressive and life-threatening lung disease with high mortality rates. The limited availability of effective drugs for IPF treatment, coupled with … This study aims to investigate the impact of KPs on …
- ケフィアペプチドは、酸化ストレス、炎症、腸内微生物叢を調節することにより、マウスのブレオマイシン誘発肺線維症を軽減
Anti-fibrotic effect of a FGF ligands trap in pulmonary fibrosis
C Scribe, D Gonçalves, P Dellugat, G Rignol, C Ghilain… - 2024
… Idiopathic Pulmonary Fibrosis (IPF) reuslts from dysfunctional wound repair involving … To better understand functions of FGFs on IPF, we evaluated the effect of a modified version … vitro on human lung fibroblasts from healthy and IPF …
- 肺線維症におけるFGFリガンドトラップの抗線維化効果
24/03/26
Subsolid Nodules: Significance and Current Understanding
L Azour, AS Oh, AE Prosper, D Toussie… - Clinics in Chest Medicine, 2024
Subsolid nodules (SSNs) include nonsolid ground-glass nodules (GGN), semisolid or partsolid nodules (PSN), and cystic nodules. Ground-glass attenuation allows visualization of the parenchymal bronchovasculature through the opacity, while solid …
- 亜固形結節: 重要性と現在の理解
24/03/25
Application of MSD on the lung cancer associated idiopathic pulmonary fibrosis
W Bao, YJ Li, JF Gu, CL Yang, YD Wang, TJ Bing… - Cancer Research, 2024
… Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible chronic disease that kill ten thousand of people in China every year. The risk of IPF is … of patients diagnosed as IPFis around 2.8 years which is less than several types of …
- 肺がん関連特発性肺線維症に対するMSDの応用
[PDF] Nintedanib in chronic fibrosing interstitial lung diseases. A case series
RG Sevila, JJA Jiménez, PV Casasempere, EN Pérez… - Heliyon, 2024
… to pulmonary fibrosis and inhibits key fibrotic processes [3,8]. Initially approved for the treatment of idiopathic pulmonary fibrosis(IPF), … the European Medicines Agency for the treatment of chronic fibrosing ILDs other than IPF. Its use in PPFs was …
- 慢性線維化性間質性肺疾患におけるニンテダニブ。 ケースシリーズ
Aberrant activation and perpetuation of lung wound response facilitates osteosarcoma metastasis
JB Reinecke, AC Gross, M Cam, LJ Garcia… - Cancer Research, 2024
… such as idiopathic pulmonary fibrosis (IPF). This process drives the accumulation of fibrotic epithelial cells and scar-associated macrophages confined within a dense fibronectin-based matrix. Anti-fibrotic tyrosine kinase inhibitors used to treat patients …
- 肺創傷反応の異常な活性化と永続が骨肉腫の転移を促進
Combining zelasudil, a small molecule ROCK2 inhibitor, with chemotherapy or immunotherapy improves response in preclinical models of pancreatic cancer
M Pajic, B McLean, DC Fajardo, S Porazinski… - Cancer Research, 2024
… of idiopathic pulmonary fibrosis (IPF) (NCT05570058). Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and therapeutically challenging disease with a dense and highly fibrotic tumor microenvironment which may limit efficacy of …
- 小分子ROCK2阻害剤であるゼラスジルと化学療法または免疫療法を組み合わせると、膵臓がんの前臨床モデルの反応が改善
24/03/23
[HTML] Identification and validation of mutual hub genes in idiopathic pulmonary fibrosis and rheumatoid arthritis-associated usual interstitial pneumonia
L Chen, H Lin, L Qin, G Zhang, D Huang, P Chen… - Heliyon, 2024
… The study aims at exploring common hub genes and pathways in idiopathic pulmonaryfibrosis (IPF) and … pulmonary fibrosis have discovered many mechanisms of IPF and other fibrotic ILDs [14]. Nowadays, we still don't fully …
- 特発性肺線維症および関節リウマチに伴う通常の間質性肺炎における相互ハブ遺伝子の同定と検証
[HTML] Exploring the causal relationship between immune cells and idiopathic pulmonary fibrosis: a bi-directional Mendelian randomization study
Z He, R Wang, C Song, J Liu, R Chen, M Zheng, W Liu… - BMC Pulmonary Medicine, 2024
… potential pathogenic mechanism of idiopathicpulmonary fibrosis is widely recognized to involve immune dysregulation. However, the current pool of studies has yet to establish a unanimous agreement regarding the correlation between …
- 免疫細胞と特発性肺線維症の因果関係の探求：双方向メンデルランダム化研究
[HTML] Respiratory oscillometry with CT image analysis in idiopathic pulmonary fibrosis following single lung transplant
JKY Wu, JJN Xu, A Vasileva, C Nohra, M Binnie… - Respiratory Medicine Case …, 2024
… Oscillometry was recently shown to be highly associated with disease severity in idiopathicpulmonary fibrosis (IPF). The usefulness of oscillometry after single lung transplant in IPFpatients is not well understood. Our study demonstrated that …
- 片肺移植後の特発性肺線維症における呼吸オシロメトリーとCT画像解析
Quantitative CT-analysis of over aerated lung tissue and correlation with fibrosis extent in patients with idiopathic pulmonary fibrosis
R Tonelli, MR Smit, I Castaniere, GD Casa, D Andrisani… - 2024
… INTRODUCTION The usual interstitial pneumonia (UIP) pattern, hallmark of idiopathicpulmonary fibrosis (IPF), may induce harmful local … Understanding the mechanical forces and aeration patterns in the lungs of IPF patients is crucial for …
- 特発性肺線維症患者における過通気肺組織の定量的 CT 解析と線維化の程度との相関
[HTML] Relative incidence of interstitial lung diseases in Brazil
SLK Matias, CAC Pereira, MR Soares, FCV Fernandes… - Jornal Brasileiro de …, 2024
… An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management. Am J … Chronic hypersensitivity pneumonitis in patients diagnosed with idiopathic pulmonaryfibrosis: a prospective …
- ブラジルにおける間質性肺疾患の相対的な発生率
Genetic factors for ILD—the path of precision medicine
G Raghu, JM Torres, RL Bennett - The Lancet Respiratory Medicine, 2024
… ILD encompasses a heterogeneous group of acute and chronic parenchymal lung diseases of known and unknown causes, including idiopathic pulmonary fibrosis (IPF). … Genetic evaluation and testing of patients and families with …
- ILDの遺伝的要因—精密医療への道
[HTML] Role of Sensory Nerves in Pulmonary Fibrosis
CE Norton - International Journal of Molecular Sciences, 2024
Pulmonary fibrosis results from the deposition and proliferation of extracellular matrix components in the lungs. Despite being an airway disorder, pulmonary fibrosis … nerve function in the context of pulmonary fibrosis as a potential tool to …
- 肺線維症における感覚神経の役割
[PDF] Effects of multi-walled carbon nanotubes on gene and microRNA expression in human hepatocarcinoma HepG2 cells
SF Thai, CP Jones, BL Robinette, H Ren, B Vallanat… - Materials Express, 2024
… The hepatic fibrosis/hepatic stellate cell activation and pulmonary fibrosis pathways were altered in all treatments. There are many reports showing lung fibrosis as one of the toxic end points of MWCNT-treated mice or rats [4, … 40 …
- ヒト肝癌 HepG2 細胞における遺伝子およびマイクロ RNA 発現に対する多層カーボンナノチューブの影響
[PDF] A Case of Tension Pneumomediastinum Treated With Mediastinal Drainage Using a Semi-flexible Fiberscope via a Subxiphoid Approach
Y Matsumoto, H Mizuuchi, K Honjo, M Hata… - Cureus, 2024
… Pneumomediastinum is a rare occurrence in patients with idiopathic pulmonary fibrosis(IPF). However, it is associated with an unfavorable outcome and can be considered a potential predictor of mortality in IPF [1]. In this report, we present a …
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特発性肺線維症( idiopathic pulmonary fibrosis (IPF) )関連の学術的情報収集してシェアしています。Google Scholar SearchのUpdateを定期的に掲載しています。GoogleのAIが一定の重み付けはしているとは思いますが、玉石混交です。
当面、毎週アラートの内容をアップしていこうと思います。
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